Phytoestrogens as natural prodrugs in cancer prevention: towards a mechanistic model

Phytochemistry Reviews

Volumn 13, Issue 4, 2014, Pages 853-866

  Arroo, Randolph R J ^a   Beresford, Kenneth ^a   Bhambra, Avninder S ^a   Boarder, Mike ^a   Budriesi, Roberta ^b   Cheng, Zhong ^c   Micucci, Matteo ^b   Ruparelia, Ketan C ^a   Surichan, Somchaiya ^d   Androutsopoulos, Vasilis P ^e  

^a DE MONTFORT UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c PEKING UNION MEDICAL COLLEGE   (China)

^d Department of Livestock Development   (Thailand)

^e UNIVERSITY OF CRETE   (Greece)

Author keywords

Cancer; Cell signalling; Chemoprevention; Cytochrome P450; Flavonoids; Polymethoxy flavones

Indexed keywords

6 HYDROXY LUTEOLIN; APIGENIN; BAICALEIN; CHRYSIN; CIRSILIOL; COUMESTAN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; DIOSMETIN; EUPATORIN; FLAVONE DERIVATIVE; FLAVONOL DERIVATIVE; GENKWANIN; ISOFLAVONE; KAEMPFERIDE; KAEMPFEROL; LIGNAN; LUTEOLIN; MITOGEN ACTIVATED PROTEIN KINASE; MYRICETIN; NOBILETIN; PHYTOESTROGEN; POLYPHENOL; QUERCETAGETIN; QUERCETIN; SINENSETIN; TAMARIXETIN; TANGERETIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; BLOOD LEVEL; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CITRUS; COLON CANCER; DEALKYLATION; DETOXIFICATION; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SUBSTRATE; FOOD INTAKE; FRUIT; HUMAN; HYDROXYLATION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MALIGNANT NEOPLASTIC DISEASE; MAMMAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; SULFONATION; TUMOR GROWTH; UTERINE CERVIX CANCER; VEGETABLE;

EID: 84912047766     PISSN: 15687767     EISSN: 1572980X     Source Type: Journal    
DOI: 10.1007/s11101-014-9355-3     Document Type: Review

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