-
2
-
-
0036955117
-
CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: Comparison with aromatic/hydrophobic adduct formation
-
K Alexandrove I Cascorbi M Rojas G Bouvier E Kriek H Bartsch 2002 CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation Carcinogenesis 23 1969 1977
-
(2002)
Carcinogenesis
, vol.23
, pp. 1969-1977
-
-
Alexandrove, K.1
Cascorbi, I.2
Rojas, M.3
Bouvier, G.4
Kriek, E.5
Bartsch, H.6
-
3
-
-
0020508747
-
Dietary carcinogens and anticarcinogens-oxygen radicals and degenerative diseases
-
BN Ames 1983 Dietary carcinogens and anticarcinogens-oxygen radicals and degenerative diseases Science 221 1256 1264
-
(1983)
Science
, vol.221
, pp. 1256-1264
-
-
Ames, B.N.1
-
4
-
-
14344267019
-
Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health
-
C Atkinson CL Frankenfeld JW Lampe 2005 Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health Exp Biol Med 230 155 170
-
(2005)
Exp Biol Med
, vol.230
, pp. 155-170
-
-
Atkinson, C.1
Frankenfeld, C.L.2
Lampe, J.W.3
-
5
-
-
33645999638
-
Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5- fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells
-
E Brantley S Antony G Kohlhagen LH Meng K Agama SF Stinson EA Sausville Y Pommier 2006 Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5- fluorobenzothiazole induces single-strand breaks and DNA-protein cross-links in sensitive MCF-7 breast cancer cells Cancer Chemother Pharmacol 58 62 72
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 62-72
-
-
Brantley, E.1
Antony, S.2
Kohlhagen, G.3
Meng, L.H.4
Agama, K.5
Stinson, S.F.6
Sausville, E.A.7
Pommier, Y.8
-
7
-
-
0016333916
-
Ethoxyresorufin-direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene
-
MD Burke RT Mayer 1974 Ethoxyresorufin-direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene Drug Metab Dispos 2 583 588
-
(1974)
Drug Metab Dispos
, vol.2
, pp. 583-588
-
-
Burke, M.D.1
Mayer, R.T.2
-
8
-
-
0041561001
-
A potential protective mechanism of soya isoflavones against tumour initiation
-
HY Chan LK Leung 2003 A potential protective mechanism of soya isoflavones against tumour initiation Brit J Nutr 90 457 465
-
(2003)
Brit J Nutr
, vol.90
, pp. 457-465
-
-
Chan, H.Y.1
Leung, L.K.2
-
9
-
-
34047225839
-
Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract
-
T Chen LP Li XY Lu HD Jiang S Zeng 2007 Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract J Agri Food Chem 55 273 277
-
(2007)
J Agri Food Chem
, vol.55
, pp. 273-277
-
-
Chen, T.1
Li, L.P.2
Lu, X.Y.3
Jiang, H.D.4
Zeng, S.5
-
11
-
-
0033659280
-
Antineoplastic agents from natural sources: Achievements and future directions
-
GM Cragg DJ Newman 2000 Antineoplastic agents from natural sources: achievements and future directions Expert Opin Investig Drugs 9 2783 2797
-
(2000)
Expert Opin Investig Drugs
, vol.9
, pp. 2783-2797
-
-
Cragg, G.M.1
Newman, D.J.2
-
12
-
-
25144471825
-
Hormone replacement therapy: Pathobiological aspects of hormone-sensitive cancers in women relevant to epidemiological studies on HRT: A mini-review
-
M Dietel MA Lewis S Shapiro 2005 Hormone replacement therapy: pathobiological aspects of hormone-sensitive cancers in women relevant to epidemiological studies on HRT: a mini-review Hum Repr 20 2052 2060
-
(2005)
Hum Repr
, vol.20
, pp. 2052-2060
-
-
Dietel, M.1
Lewis, M.A.2
Shapiro, S.3
-
14
-
-
0142124242
-
Phytoestrogens: Potential benefits and implications for breast cancer survivors
-
C Duffy M Cyr 2003 Phytoestrogens: Potential benefits and implications for breast cancer survivors J Women Health 12 617 631
-
(2003)
J Women Health
, vol.12
, pp. 617-631
-
-
Duffy, C.1
Cyr, M.2
-
15
-
-
3142727692
-
Absorption of kaempferol from endive, a source of kaempferol-3- glucuronide, in humans
-
MS DuPont AJ Day RN Bennett FA Mellon PA Kroon 2004 Absorption of kaempferol from endive, a source of kaempferol-3-glucuronide, in humans Eur J Clin Nutr 58 947 954
-
(2004)
Eur J Clin Nutr
, vol.58
, pp. 947-954
-
-
Dupont, M.S.1
Day, A.J.2
Bennett, R.N.3
Mellon, F.A.4
Kroon, P.A.5
-
16
-
-
33947595267
-
Effect of flavonoids on glutathione level, lipid peroxidation and cytochrome P450CYP1A1 expression in human laryngeal carcinoma cell lines
-
K Durgo L Vukovic G Rusak M Osmak JF Colic 2007 Effect of flavonoids on glutathione level, lipid peroxidation and cytochrome P450CYP1A1 expression in human laryngeal carcinoma cell lines Food Tech Biotech 45 69 79
-
(2007)
Food Tech Biotech
, vol.45
, pp. 69-79
-
-
Durgo, K.1
Vukovic, L.2
Rusak, G.3
Osmak, M.4
Colic, J.F.5
-
17
-
-
10044246299
-
Review of the flavonoids quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability, and epidemiology
-
I Erlund 2004 Review of the flavonoids quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability, and epidemiology Nutri Res 24 851 874
-
(2004)
Nutri Res
, vol.24
, pp. 851-874
-
-
Erlund, I.1
-
18
-
-
0021276662
-
Use of potato disk and brine shrimp bioassays to detect activity and isolate piceatannol as the antileukemic principle from the seeds of Euphorbia-lagascae
-
NR Ferrigni JL Mclaughlin RG Powell CR Smith 1984 Use of potato disk and brine shrimp bioassays to detect activity and isolate piceatannol as the antileukemic principle from the seeds of Euphorbia-lagascae J Nat Prod 47 347 352
-
(1984)
J Nat Prod
, vol.47
, pp. 347-352
-
-
Ferrigni, N.R.1
McLaughlin, J.L.2
Powell, R.G.3
Smith, C.R.4
-
19
-
-
1542544380
-
Cytochrome P450 1B1 (CYP1B1) is overexpressed in human colon adenocarcinomas relative to normal colon: Implications for drug development
-
P Gibson JH Gill PA Khan JM Seargent SW Martin PA Batman J Griffith C Bradley JA Double MC Bibby PM Loadman 2003 Cytochrome P450 1B1 (CYP1B1) is overexpressed in human colon adenocarcinomas relative to normal colon: Implications for drug development Mol Cancer Ther 2 527 53
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 527-53
-
-
Gibson, P.1
Gill, J.H.2
Khan, P.A.3
Seargent, J.M.4
Martin, S.W.5
Batman, P.A.6
Griffith, J.7
Bradley, C.8
Double, J.A.9
Bibby, M.C.10
Loadman, P.M.11
-
21
-
-
0034176645
-
The antioxidant paradox
-
B Halliwell 2000 The antioxidant paradox The Lancet 335 1179 1180
-
(2000)
The Lancet
, vol.335
, pp. 1179-1180
-
-
Halliwell, B.1
-
22
-
-
33845580481
-
Dietary polyphenols: Good, bad, or indifferent for your health?
-
B Halliwell 2007 Dietary polyphenols: Good, bad, or indifferent for your health? Cardiovascular Res 73 341 347
-
(2007)
Cardiovascular Res
, vol.73
, pp. 341-347
-
-
Halliwell, B.1
-
23
-
-
13844298231
-
Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: Direct or indirect effects? Antioxidant or not?
-
Halliwell B, Rafter J, Jenner A (2005) Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not? Am J Clin Nutr 81:268S-276S
-
(2005)
Am J Clin Nutr
, vol.81
-
-
Halliwell, B.1
Rafter, J.2
Jenner, A.3
-
24
-
-
34047217681
-
Toxicological aspects of flavonoid interaction with biomacromolecules.
-
2
-
P Hodek P Hanustiak J Krizkova R Mikelova S Krizkova M Stiborova L Trnkova A Horna M Beklova R Kizek 2006 Toxicological aspects of flavonoid interaction with biomacromolecules. Neuroendocrin Lett 27 2 14 17
-
(2006)
Neuroendocrin Lett
, vol.27
, pp. 14-17
-
-
Hodek, P.1
Hanustiak, P.2
Krizkova, J.3
Mikelova, R.4
Krizkova, S.5
Stiborova, M.6
Trnkova, L.7
Horna, A.8
Beklova, M.9
Kizek, R.10
-
25
-
-
0031561513
-
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
-
MS Jang EN Cai GO Udeani KV Slowing CF Thomas CWW Beecher HHS Fong NR Farnsworth AD Kinghorn RG Mehta RC Moon JM Pezzuto 1997 Cancer chemopreventive activity of resveratrol, a natural product derived from grapes Science 275 218 220
-
(1997)
Science
, vol.275
, pp. 218-220
-
-
Jang, M.S.1
Cai, E.N.2
Udeani, G.O.3
Slowing, K.V.4
Thomas, C.F.5
Beecher, C.W.W.6
Fong, H.H.S.7
Farnsworth, N.R.8
Kinghorn, A.D.9
Mehta, R.G.10
Moon, R.C.11
Pezzuto, J.M.12
-
26
-
-
0032994292
-
Cancer chemopreventive activity of resveratrol
-
M Jang JM Pezzuto 1999 Cancer chemopreventive activity of resveratrol Drug Exp Clin Res 25 65 77
-
(1999)
Drug Exp Clin Res
, vol.25
, pp. 65-77
-
-
Jang, M.1
Pezzuto, J.M.2
-
27
-
-
0037305385
-
Cancer chemopreventive agents discovered by activity-guided fractionation: An update
-
AD Kinghorn BN Su D Lee JQ Gu JM Pezzuto 2003 Cancer chemopreventive agents discovered by activity-guided fractionation: An update Curr Org Chem 7 213 226
-
(2003)
Curr Org Chem
, vol.7
, pp. 213-226
-
-
Kinghorn, A.D.1
Su, B.N.2
Lee, D.3
Gu, J.Q.4
Pezzuto, J.M.5
-
28
-
-
4444372747
-
Natural inhibitors of carcinogenesis
-
AD Kinghorn BN Su DS Jang LC Chang D Lee JQ Gu EJ Carcache-Blanco AD Powlus SK Lee EJ Park M Cuendet JJ Gills K Bhat HS Park E Mata-Greenwood LL Song MH Jong JM Pezzuto 2004 Natural inhibitors of carcinogenesis Planta Medica 70 691 705
-
(2004)
Planta Medica
, vol.70
, pp. 691-705
-
-
Kinghorn, A.D.1
Su, B.N.2
Jang, D.S.3
Chang, L.C.4
Lee, D.5
Gu, J.Q.6
Carcache-Blanco, E.J.7
Powlus, A.D.8
Lee, S.K.9
Park, E.J.10
Cuendet, M.11
Gills, J.J.12
Bhat, K.13
Park, H.S.14
Mata-Greenwood, E.15
Song, L.L.16
Jong, M.H.17
Pezzuto, J.M.18
-
32
-
-
0035711406
-
Vegetables, fruit, antioxidants and cancer: A review of Italian studies
-
C La Vecchia A Altieri A Tavani 2001 Vegetables, fruit, antioxidants and cancer: a review of Italian studies Eur J Nutr 40 261 267
-
(2001)
Eur J Nutr
, vol.40
, pp. 261-267
-
-
La Vecchia, C.1
Altieri, A.2
Tavani, A.3
-
33
-
-
0035116497
-
Resveratrol analogue 3,4,5,4′-tetrahydroxystilbene differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts
-
J Lu C Ho G Ghai KJ Chen 2001 Resveratrol analogue 3,4,5,4′- tetrahydroxystilbene differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts Carcinogenesis 22 321 328
-
(2001)
Carcinogenesis
, vol.22
, pp. 321-328
-
-
Lu, J.1
Ho, C.2
Ghai, G.3
Chen, K.J.4
-
34
-
-
4444223732
-
Cytochrome P450 enzymes: Novel options for cancer therapeutics
-
MCE McFadyen WT Melvin GI Murray 2004 Cytochrome P450 enzymes: Novel options for cancer therapeutics Mol Cancer Ther 3 363 371
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 363-371
-
-
McFadyen, M.C.E.1
Melvin, W.T.2
Murray, G.I.3
-
35
-
-
30644456411
-
Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism
-
YJ Moon XD Wang ME Morris 2006 Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism Toxicol In Vitro 20 187 210
-
(2006)
Toxicol in Vitro
, vol.20
, pp. 187-210
-
-
Moon, Y.J.1
Wang, X.D.2
Morris, M.E.3
-
37
-
-
0035036154
-
Regulation, function, and tissuespecific expression of cytochrome P450 CYP1B1
-
GI Murray WT Melvin WF Greenlee MD Burke 2001 Regulation, function, and tissuespecific expression of cytochrome P450 CYP1B1 Annu Rev Pharmacol Toxicol 41 297 316
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 297-316
-
-
Murray, G.I.1
Melvin, W.T.2
Greenlee, W.F.3
Burke, M.D.4
-
40
-
-
32544453858
-
CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines
-
LJ Pobst MM Ames 2006 CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines Cancer Chemother Pharmacol 57 569 576
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 569-576
-
-
Pobst, L.J.1
Ames, M.M.2
-
41
-
-
33846513021
-
Cytochrome p450 1A1 expression and activity in Caco-2 cells: Modulation by apple juice extract and certain apple polyphenols
-
C Pohl F Will H Dietrich D Schrenk 2006 Cytochrome p450 1A1 expression and activity in Caco-2 cells: Modulation by apple juice extract and certain apple polyphenols J Agric Food Chem 54 10262 10268
-
(2006)
J Agric Food Chem
, vol.54
, pp. 10262-10268
-
-
Pohl, C.1
Will, F.2
Dietrich, H.3
Schrenk, D.4
-
42
-
-
48449085440
-
3,4-Methylenedioxy-substituted chalcones as therapeutic agents
-
Patent Application Publication US2004/0254149 A1
-
Potter GA, Butler PC (2004) 3,4-Methylenedioxy-substituted chalcones as therapeutic agents. Patent Application Publication US2004/0254149 A1
-
(2004)
-
-
Potter, G.A.1
Butler, P.C.2
-
43
-
-
18344372908
-
The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1
-
GA Potter LH Patterson E Wanogho PJ Perry PC Butler T Ijaz KC Ruparelia JH Lamb PB Farmer LA Stanley MD Burke 2002 The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1 Brit J Cancer 86 774 778
-
(2002)
Brit J Cancer
, vol.86
, pp. 774-778
-
-
Potter, G.A.1
Patterson, L.H.2
Wanogho, E.3
Perry, P.J.4
Butler, P.C.5
Ijaz, T.6
Ruparelia, K.C.7
Lamb, J.H.8
Farmer, P.B.9
Stanley, L.A.10
Burke, M.D.11
-
44
-
-
0029777340
-
Dose dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed
-
SE Rickard LJ Orcheson MM Seidl L Luyengi HHS Fong LU Thompson 1996 Dose dependent production of mammalian lignans in rats and in vitro from the purified precursor secoisolariciresinol diglycoside in flaxseed J Nutr 126 2012 2019
-
(1996)
J Nutr
, vol.126
, pp. 2012-2019
-
-
Rickard, S.E.1
Orcheson, L.J.2
Seidl, M.M.3
Luyengi, L.4
Fong, H.H.S.5
Thompson, L.U.6
-
47
-
-
10744229260
-
Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene
-
S Sale RD Verschoyle D Boocock DJL Jones N Wilsher KC Ruparelia GA Potter PB Farmer WP Steward AJ Gescher 2004 Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene Brit J Cancer 90 736 744
-
(2004)
Brit J Cancer
, vol.90
, pp. 736-744
-
-
Sale, S.1
Verschoyle, R.D.2
Boocock, D.3
Jones, D.J.L.4
Wilsher, N.5
Ruparelia, K.C.6
Potter, G.A.7
Farmer, P.B.8
Steward, W.P.9
Gescher, A.J.10
-
48
-
-
0031738302
-
Intestinal absorption of luteolin and luteolin 7-O-L-glucoside in rats and humans
-
K Shimoi H Okada M Furugori T Goda S Takase M Suzuki Y Hara H Yamamoto N Kinae 1998 Intestinal absorption of luteolin and luteolin 7-O-L-glucoside in rats and humans FEBS Lett 438 220 224
-
(1998)
FEBS Lett
, vol.438
, pp. 220-224
-
-
Shimoi, K.1
Okada, H.2
Furugori, M.3
Goda, T.4
Takase, S.5
Suzuki, M.6
Hara, Y.7
Yamamoto, H.8
Kinae, N.9
-
49
-
-
33747745146
-
Cytochrome P450 CYP1B1 in colon tumorigenesis
-
Stanley LA, Ball MT, Eaden J, Potter GA, Rolls S, Burke MD (2001a) Cytochrome P450 CYP1B1 in colon tumorigenesis. Drug Metab Rev 33(Suppl 1):62
-
(2001)
Drug Metab Rev
, vol.33
, Issue.SUPPL. 1
, pp. 62
-
-
Stanley, L.A.1
Ball, M.T.2
Eaden, J.3
Potter, G.A.4
Rolls, S.5
Burke, M.D.6
-
50
-
-
48449084438
-
CYP1B1 expression in human cervical abnormalities
-
Stanley LA, Ball MT, Butler PC, Hoang TTV, Potter GA & Burke MD (2001b) CYP1B1 expression in human cervical abnormalities. Drug Metab Rev 33(Suppl 1):77
-
(2001)
Drug Metab Rev
, vol.33
, Issue.SUPPL. 1
, pp. 77
-
-
Stanley, L.A.1
Ball, M.T.2
Butler, P.C.3
Hoang, T.T.V.4
Potter, G.A.5
Burke, M.D.6
-
51
-
-
12944312687
-
50 Years of Preclinical anticancer drug screening: Empirical to target-driven approaches
-
M Suggitt C Bibby 2005 50 Years of Preclinical anticancer drug screening: Empirical to target-driven approaches Clin Cancer Res 11 971 981
-
(2005)
Clin Cancer Res
, vol.11
, pp. 971-981
-
-
Suggitt, M.1
Bibby, C.2
-
52
-
-
23844494772
-
Cytochrome P450-mediated metabolism of estrogens and its regulation in human
-
Y Tsuchiya M Nakajima T Yokoi 2005 Cytochrome P450-mediated metabolism of estrogens and its regulation in human Cancer Lett 227 115 124
-
(2005)
Cancer Lett
, vol.227
, pp. 115-124
-
-
Tsuchiya, Y.1
Nakajima, M.2
Yokoi, T.3
-
53
-
-
33747890916
-
Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids
-
PA Tsuji T Walle 2006 Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids Carcinogenesis 27 1579 1585
-
(2006)
Carcinogenesis
, vol.27
, pp. 1579-1585
-
-
Tsuji, P.A.1
Walle, T.2
-
54
-
-
33645000494
-
Pharmaceutical prospects of phytoestrogens
-
T Usui 2006 Pharmaceutical prospects of phytoestrogens Endocr J 53 7 20
-
(2006)
Endocr J
, vol.53
, pp. 7-20
-
-
Usui, T.1
-
56
-
-
0346365445
-
Smart drugs in prostate cancer
-
HG van der Poel 2004 Smart drugs in prostate cancer Eur Urol 45 1 17
-
(2004)
Eur Urol
, vol.45
, pp. 1-17
-
-
Van Der Poel, H.G.1
-
57
-
-
33845348869
-
Xenobiotic-metabolizing enzymes in human lung
-
JY Zhang Y Wang C Prakash 2006 Xenobiotic-metabolizing enzymes in human lung Curr Drug Metab 7 939 948
-
(2006)
Curr Drug Metab
, vol.7
, pp. 939-948
-
-
Zhang, J.Y.1
Wang, Y.2
Prakash, C.3
|