Stereoselective conjugation, transport and bioactivity of S- and R-hesperetin enantiomers in vitro

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 10, 2010, Pages 6119-6125

  Brand, Walter ^a,b   Shao, Jia ^a   Hoek Van Den Hil, Elisabeth F ^a   Van Elk, Kathelijn N ^a   Spenkelink, Bert ^a   De Haan, Laura H J ^a   Rein, Maarit J ^b   Dionisi, Fabiola ^b   Williamson, Gary ^b,c   Van Bladeren, Peter J ^a,b   Rietjens, Ivonne M C M ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Chirality; Conjugation; Flavonoid; HPLC; Stereoselectivity

Indexed keywords

GLUCURONIDE; HESPERETIN; HESPERIDIN; SULFONIC ACID DERIVATIVE;

ANIMAL; ARTICLE; CELL STRAIN CACO 2; CHEMISTRY; CYTOSOL; DNA RESPONSIVE ELEMENT; DRUG EFFECT; FRUIT; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HUMAN; LIVER MICROSOME; LIVER TUMOR; METABOLISM; MOUSE; SMALL INTESTINE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SWEET ORANGE; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; ULTRASTRUCTURE; CACO 2 CELL LINE; DRUG EFFECTS; EXPERIMENTAL LIVER NEOPLASM;

ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL LINE, TUMOR; CITRUS SINENSIS; CYTOSOL; FRUIT; GENE EXPRESSION; GLUCURONIDES; HESPERIDIN; HUMANS; INTESTINE, SMALL; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICROSOMES, LIVER; RESPONSE ELEMENTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS; TRANSFECTION;

CITRUS SINENSIS;

EID: 77952646388     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf1008617     Document Type: Article

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