메뉴 건너뛰기




Volumn 431, Issue 3, 2013, Pages 530-534

Characteristics of nobiletin-mediated alteration of gene expression in cultured cell lines

Author keywords

Cell proliferation; Citrus peel; DNA microarray; Endoplasmic reticulum stress; Nobiletin; Oxidative stress

Indexed keywords

ASPARTATE AMMONIA LIGASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; NOBILETIN; THIOREDOXIN INTERACTING PROTEIN;

EID: 84873722140     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.01.024     Document Type: Article
Times cited : (29)

References (54)
  • 1
    • 27144554955 scopus 로고    scopus 로고
    • Nobiletin and its related flavonoids with CRE-dependent transcription-stimulating and neuritegenic activities
    • Nagase H., Omae N., Omori A., et al. Nobiletin and its related flavonoids with CRE-dependent transcription-stimulating and neuritegenic activities. Biochem. Biophys. Res. Commun. 2005, 337:1330-1336.
    • (2005) Biochem. Biophys. Res. Commun. , vol.337 , pp. 1330-1336
    • Nagase, H.1    Omae, N.2    Omori, A.3
  • 2
    • 33646261868 scopus 로고    scopus 로고
    • Nobiletin restoring β-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats
    • Matsuzaki K., Yamakuni T., Hashimoto M., et al. Nobiletin restoring β-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats. Neurosci. Lett. 2006, 400:230-234.
    • (2006) Neurosci. Lett. , vol.400 , pp. 230-234
    • Matsuzaki, K.1    Yamakuni, T.2    Hashimoto, M.3
  • 3
    • 34648824442 scopus 로고    scopus 로고
    • Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice
    • Nakajima A., Yamakuni T., Haraguchi M., et al. Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice. J. Pharmacol. Sci. 2007, 105:122-126.
    • (2007) J. Pharmacol. Sci. , vol.105 , pp. 122-126
    • Nakajima, A.1    Yamakuni, T.2    Haraguchi, M.3
  • 4
    • 34247246338 scopus 로고    scopus 로고
    • Nobiletin, a citrus flavonoid, reverses learning impairment associated with N-methyl-d-aspartate receptor antagonism by activation of extracellular signal-regulated kinase signaling
    • Nakajima A., Yamakuni T., Matsuzaki K., et al. Nobiletin, a citrus flavonoid, reverses learning impairment associated with N-methyl-d-aspartate receptor antagonism by activation of extracellular signal-regulated kinase signaling. J. Pharmacol. Exp. Ther. 2007, 321:784-790.
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 784-790
    • Nakajima, A.1    Yamakuni, T.2    Matsuzaki, K.3
  • 5
    • 37349106293 scopus 로고    scopus 로고
    • Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus
    • Matsuzaki K., Miyazaki K., Sakai S., et al. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. Eur. J. Pharmacol. 2008, 578:194-200.
    • (2008) Eur. J. Pharmacol. , vol.578 , pp. 194-200
    • Matsuzaki, K.1    Miyazaki, K.2    Sakai, S.3
  • 6
    • 53849087537 scopus 로고    scopus 로고
    • Nobiletin, a citrus flavonoid, improves memory impairment and Aβ pathology in a transgenic mouse model of Alzheimer's disease
    • Onozuka H., Nakajima A., Matsuzaki K., et al. Nobiletin, a citrus flavonoid, improves memory impairment and Aβ pathology in a transgenic mouse model of Alzheimer's disease. J. Pharmacol. Exp. Ther. 2008, 326:739-744.
    • (2008) J. Pharmacol. Exp. Ther. , vol.326 , pp. 739-744
    • Onozuka, H.1    Nakajima, A.2    Matsuzaki, K.3
  • 7
    • 70349260102 scopus 로고    scopus 로고
    • Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation
    • Yamamoto Y., Shioda N., Han F., et al. Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation. Brain Res. 2009, 1295:218-229.
    • (2009) Brain Res. , vol.1295 , pp. 218-229
    • Yamamoto, Y.1    Shioda, N.2    Han, F.3
  • 8
    • 78049500586 scopus 로고    scopus 로고
    • Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin
    • Yi L.T., Xu H.L., Feng J., et al. Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin. Physiol. Behav. 2011, 102:1-6.
    • (2011) Physiol. Behav. , vol.102 , pp. 1-6
    • Yi, L.T.1    Xu, H.L.2    Feng, J.3
  • 9
    • 0034665123 scopus 로고    scopus 로고
    • Inhibitory effect of citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice
    • Murakami A., Nakamura Y., Torikai K., et al. Inhibitory effect of citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice. Cancer Res. 2000, 60:5059-5066.
    • (2000) Cancer Res. , vol.60 , pp. 5059-5066
    • Murakami, A.1    Nakamura, Y.2    Torikai, K.3
  • 10
    • 0036173982 scopus 로고    scopus 로고
    • Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells
    • Sato T., Koike L., Miyata Y., et al. Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells. Cancer Res. 2002, 62:1025-1029.
    • (2002) Cancer Res. , vol.62 , pp. 1025-1029
    • Sato, T.1    Koike, L.2    Miyata, Y.3
  • 11
    • 0036035557 scopus 로고    scopus 로고
    • Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells
    • Zheng Q., Hirose Y., Yoshimi N., et al. Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells. J. Cancer Res. Clin. Oncol. 2002, 128:539-546.
    • (2002) J. Cancer Res. Clin. Oncol. , vol.128 , pp. 539-546
    • Zheng, Q.1    Hirose, Y.2    Yoshimi, N.3
  • 12
    • 4444331025 scopus 로고    scopus 로고
    • 2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin
    • 2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin. Mol. Cancer Ther. 2004, 3:839-847.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 839-847
    • Miyata, Y.1    Sato, T.2    Yano, M.3    Ito, A.4
  • 13
    • 19944427056 scopus 로고    scopus 로고
    • Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo
    • Ohnishi H., Asamoto M., Tujimura K., et al. Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo. Cancer Sci. 2004, 95:936-942.
    • (2004) Cancer Sci. , vol.95 , pp. 936-942
    • Ohnishi, H.1    Asamoto, M.2    Tujimura, K.3
  • 14
    • 34247137191 scopus 로고    scopus 로고
    • Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells
    • Morley K.L., Ferguson P.J., Koropatnick J. Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells. Cancer Lett. 2007, 251:168-178.
    • (2007) Cancer Lett. , vol.251 , pp. 168-178
    • Morley, K.L.1    Ferguson, P.J.2    Koropatnick, J.3
  • 15
    • 34147146571 scopus 로고    scopus 로고
    • Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells
    • Tang M., Ogawa K., Asamoto M., et al. Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells. Cancer Sci. 2007, 98:471-477.
    • (2007) Cancer Sci. , vol.98 , pp. 471-477
    • Tang, M.1    Ogawa, K.2    Asamoto, M.3
  • 16
    • 40949149451 scopus 로고    scopus 로고
    • Interactive effects of polymethoxy flavones from Citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells
    • Akao Y., Itoh T., Ohguchi K., et al. Interactive effects of polymethoxy flavones from Citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells. Bioorg. Med. Chem. 2008, 16:2803-2810.
    • (2008) Bioorg. Med. Chem. , vol.16 , pp. 2803-2810
    • Akao, Y.1    Itoh, T.2    Ohguchi, K.3
  • 17
    • 56149116774 scopus 로고    scopus 로고
    • Apoptotic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo
    • Luo G., Guan X., Zhou L. Apoptotic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo. Cancer Biol. Ther. 2008, 7:966-973.
    • (2008) Cancer Biol. Ther. , vol.7 , pp. 966-973
    • Luo, G.1    Guan, X.2    Zhou, L.3
  • 18
    • 47249110701 scopus 로고    scopus 로고
    • Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice
    • Miyamoto S., Yasui Y., Tanaka T., et al. Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice. Carcinogenesis 2008, 29:1057-1063.
    • (2008) Carcinogenesis , vol.29 , pp. 1057-1063
    • Miyamoto, S.1    Yasui, Y.2    Tanaka, T.3
  • 19
    • 37349052385 scopus 로고    scopus 로고
    • A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells
    • Miyata Y., Sato T., Imada K., et al. A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells. Biochem. Biophys. Res. Commun. 2008, 366:168-173.
    • (2008) Biochem. Biophys. Res. Commun. , vol.366 , pp. 168-173
    • Miyata, Y.1    Sato, T.2    Imada, K.3
  • 20
    • 77958611254 scopus 로고    scopus 로고
    • Nobiletin, a citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo
    • Kunimasa K., Ikekita M., Sato M., et al. Nobiletin, a citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo. Cancer Sci. 2010, 101:2462-2469.
    • (2010) Cancer Sci. , vol.101 , pp. 2462-2469
    • Kunimasa, K.1    Ikekita, M.2    Sato, M.3
  • 21
    • 72149105299 scopus 로고    scopus 로고
    • Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice
    • Miyamoto S., Yasui Y., Ohigashi H., et al. Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice. Chem. Biol. Interact. 2010, 183:276-283.
    • (2010) Chem. Biol. Interact. , vol.183 , pp. 276-283
    • Miyamoto, S.1    Yasui, Y.2    Ohigashi, H.3
  • 22
    • 78651303014 scopus 로고    scopus 로고
    • Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells
    • Lee Y.C., Cheng T.H., Lee J.S., et al. Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells. Mol. Cell. Biochem. 2011, 347:103-115.
    • (2011) Mol. Cell. Biochem. , vol.347 , pp. 103-115
    • Lee, Y.C.1    Cheng, T.H.2    Lee, J.S.3
  • 23
    • 79951884253 scopus 로고    scopus 로고
    • Effects of nobiletin on PhIP-induced prostate and colon carcinogenesis in F344 rats
    • Tang M.X., Ogawa K., Asamoto M., et al. Effects of nobiletin on PhIP-induced prostate and colon carcinogenesis in F344 rats. Nutr. Cancer 2011, 63:227-233.
    • (2011) Nutr. Cancer , vol.63 , pp. 227-233
    • Tang, M.X.1    Ogawa, K.2    Asamoto, M.3
  • 24
    • 34247101939 scopus 로고    scopus 로고
    • Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes
    • Saito T., Abe D., Sekiya K. Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 2007, 357:371-376.
    • (2007) Biochem. Biophys. Res. Commun. , vol.357 , pp. 371-376
    • Saito, T.1    Abe, D.2    Sekiya, K.3
  • 25
    • 61849093805 scopus 로고    scopus 로고
    • Identification of nobiletin, a polymethoxyflavonoid, as an enhancer of adiponectin secretion
    • Kunimasa K., Kuranuki S., Matsuura N., et al. Identification of nobiletin, a polymethoxyflavonoid, as an enhancer of adiponectin secretion. Bioorg. Med. Chem. Lett. 2009, 19:2062-2064.
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 2062-2064
    • Kunimasa, K.1    Kuranuki, S.2    Matsuura, N.3
  • 26
    • 77950078871 scopus 로고    scopus 로고
    • Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice
    • Lee Y.S., Cha B.Y., Saito K., et al. Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice. Biochem. Pharmacol. 2010, 79:1674-1683.
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 1674-1683
    • Lee, Y.S.1    Cha, B.Y.2    Saito, K.3
  • 27
    • 84255197158 scopus 로고    scopus 로고
    • Nobiletin suppresses adipogenesis by regulating the expression of adipogenic transcription factors and the activation of AMP-activated protein kinase (AMPK)
    • Choi Y., Kim Y., Ham H., et al. Nobiletin suppresses adipogenesis by regulating the expression of adipogenic transcription factors and the activation of AMP-activated protein kinase (AMPK). J. Agric. Food Chem. 2011, 59:12843-12849.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 12843-12849
    • Choi, Y.1    Kim, Y.2    Ham, H.3
  • 28
    • 79955681996 scopus 로고    scopus 로고
    • Molecular structures of citrus flavonoids determine their effects on lipid metabolism in HepG2 cells by primarily suppressing apoB secretion
    • Lin Y., Vermeer M.A., Bos W., et al. Molecular structures of citrus flavonoids determine their effects on lipid metabolism in HepG2 cells by primarily suppressing apoB secretion. J. Agric. Food Chem. 2011, 59:4496-4503.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 4496-4503
    • Lin, Y.1    Vermeer, M.A.2    Bos, W.3
  • 29
    • 79952700752 scopus 로고    scopus 로고
    • Regulation of adipocytokine secretion and adipocyte hypertrophy by polymethoxyflavonoids, nobiletin and tangeretin
    • Miyata Y., Tanaka H., Shimada A., et al. Regulation of adipocytokine secretion and adipocyte hypertrophy by polymethoxyflavonoids, nobiletin and tangeretin. Life Sci. 2011, 88:613-618.
    • (2011) Life Sci. , vol.88 , pp. 613-618
    • Miyata, Y.1    Tanaka, H.2    Shimada, A.3
  • 30
    • 84857340432 scopus 로고
    • Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction
    • Kanda K., Nishi K., Kadota A., et al. Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction. Biochim. Biophys. Acta. 1820, 2012:461-468.
    • (1820) Biochim. Biophys. Acta. , vol.2012 , pp. 461-468
    • Kanda, K.1    Nishi, K.2    Kadota, A.3
  • 31
    • 0038054004 scopus 로고    scopus 로고
    • Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages
    • Lin N., Sato T., Takayama Y., et al. Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages. Biochem. Pharmacol. 2003, 65:2065-2071.
    • (2003) Biochem. Pharmacol. , vol.65 , pp. 2065-2071
    • Lin, N.1    Sato, T.2    Takayama, Y.3
  • 32
    • 3042785880 scopus 로고    scopus 로고
    • Prevention of UVB-induced photoinflammation and photoaging by a polymethoxy flavonoid, nobiletin, in human keratinocytes in vivo and in vitro
    • Tanaka S., Sato T., Akimoto N., et al. Prevention of UVB-induced photoinflammation and photoaging by a polymethoxy flavonoid, nobiletin, in human keratinocytes in vivo and in vitro. Biochem. Pharmacol. 2004, 68:433-439.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 433-439
    • Tanaka, S.1    Sato, T.2    Akimoto, N.3
  • 33
    • 34447503642 scopus 로고    scopus 로고
    • Nobiletin from citrus fruit peel inhibits the DNA-binding activity of NF-κB and ROS production in LPS-activated RAW 264.7 cells
    • Choi S.Y., Hwang J.H., Ko H.C., et al. Nobiletin from citrus fruit peel inhibits the DNA-binding activity of NF-κB and ROS production in LPS-activated RAW 264.7 cells. J. Ethnopharmacol. 2007, 113:149-155.
    • (2007) J. Ethnopharmacol. , vol.113 , pp. 149-155
    • Choi, S.Y.1    Hwang, J.H.2    Ko, H.C.3
  • 34
    • 34147139570 scopus 로고    scopus 로고
    • Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits
    • Choi S.Y., Ko H.C., Ko S.Y., et al. Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits. Biol. Pharm. Bull. 2007, 30:772-778.
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 772-778
    • Choi, S.Y.1    Ko, H.C.2    Ko, S.Y.3
  • 35
    • 40649085017 scopus 로고    scopus 로고
    • Sp1 is an essential transcription factor for LPS-induced tissue factor expression in THP-1 monocytic cells, and nobiletin represses the expression through inhibition of NF-κB, AP-1, and Sp1 activation
    • Hirata Y., Masuda Y., Kakutani H., et al. Sp1 is an essential transcription factor for LPS-induced tissue factor expression in THP-1 monocytic cells, and nobiletin represses the expression through inhibition of NF-κB, AP-1, and Sp1 activation. Biochem. Pharmacol. 2008, 75:1504-1514.
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 1504-1514
    • Hirata, Y.1    Masuda, Y.2    Kakutani, H.3
  • 36
    • 27144472889 scopus 로고    scopus 로고
    • Mechanism of neurotrophic action of nobiletin in PC12D cells
    • Nagase H., Yamakuni T., Matsuzaki K., et al. Mechanism of neurotrophic action of nobiletin in PC12D cells. Biochemistry 2005, 44:13683-13691.
    • (2005) Biochemistry , vol.44 , pp. 13683-13691
    • Nagase, H.1    Yamakuni, T.2    Matsuzaki, K.3
  • 37
    • 1842843855 scopus 로고    scopus 로고
    • Roles of CHOP/GADD153 in endoplasmic reticulum stress
    • Oyadomari S., Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11:381-389.
    • (2004) Cell Death Differ. , vol.11 , pp. 381-389
    • Oyadomari, S.1    Mori, M.2
  • 38
    • 58849102749 scopus 로고    scopus 로고
    • DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis
    • Jakobsen C.H., Storvold G.L., Bremseth H., et al. DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis. J. Lipid Res. 2008, 49:2089-2100.
    • (2008) J. Lipid Res. , vol.49 , pp. 2089-2100
    • Jakobsen, C.H.1    Storvold, G.L.2    Bremseth, H.3
  • 39
    • 79952264011 scopus 로고    scopus 로고
    • Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
    • Tabas I., Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat. Cell Biol. 2011, 13:184-190.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 184-190
    • Tabas, I.1    Ron, D.2
  • 40
    • 77954214884 scopus 로고    scopus 로고
    • Anti-oxidative, anti-cancer and anti-inflammatory actions by thioredoxin 1 and thioredoxin-binding protein-2
    • Watanabe R., Nakamura H., Masutani H., Yodoi J. Anti-oxidative, anti-cancer and anti-inflammatory actions by thioredoxin 1 and thioredoxin-binding protein-2. Pharmacol. Ther. 2010, 127:261-270.
    • (2010) Pharmacol. Ther. , vol.127 , pp. 261-270
    • Watanabe, R.1    Nakamura, H.2    Masutani, H.3    Yodoi, J.4
  • 41
    • 80255134542 scopus 로고    scopus 로고
    • TXNIP (VDUP-1, TBP-2): A major redox regulator commonly suppressed in cancer by epigenetic mechanisms
    • Zhou J., Yu Q., Chng W.J. TXNIP (VDUP-1, TBP-2): A major redox regulator commonly suppressed in cancer by epigenetic mechanisms. Int. J. Biochem. Cell Biol. 2011, 43:1668-1673.
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 1668-1673
    • Zhou, J.1    Yu, Q.2    Chng, W.J.3
  • 42
    • 84855415247 scopus 로고    scopus 로고
    • Thioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins in cancer and diabetes mellitus
    • Masutani H., Yoshihara E., Masaki S., Chen Z., Yodoi J. Thioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins in cancer and diabetes mellitus. J. Clin. Biochem. Nutr. 2012, 50:23-34.
    • (2012) J. Clin. Biochem. Nutr. , vol.50 , pp. 23-34
    • Masutani, H.1    Yoshihara, E.2    Masaki, S.3    Chen, Z.4    Yodoi, J.5
  • 43
    • 77953196716 scopus 로고    scopus 로고
    • Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity
    • Chutkow W.A., Birkenfeld A.L., Brown J.D., et al. Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity. Diabetes 2010, 59:1424-1434.
    • (2010) Diabetes , vol.59 , pp. 1424-1434
    • Chutkow, W.A.1    Birkenfeld, A.L.2    Brown, J.D.3
  • 44
    • 84859761969 scopus 로고    scopus 로고
    • The complexity of sporadic Alzheimer's disease pathogenesis: The role of RAGE as therapeutic target to promote neuroprotection by inhibiting neurovascular dysfunction
    • Perrone L., Sbai O., Nawroth P.P., Bierhaus A. The complexity of sporadic Alzheimer's disease pathogenesis: The role of RAGE as therapeutic target to promote neuroprotection by inhibiting neurovascular dysfunction. Int. J. Alzheimer's Dis. 2012, 2012:734956.
    • (2012) Int. J. Alzheimer's Dis. , vol.2012 , pp. 734956
    • Perrone, L.1    Sbai, O.2    Nawroth, P.P.3    Bierhaus, A.4
  • 45
    • 33749521100 scopus 로고    scopus 로고
    • Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation
    • Oakley H., Cole S.L., Logan S., et al. Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation. J. Neurosci. 2006, 26:10129-10140.
    • (2006) J. Neurosci. , vol.26 , pp. 10129-10140
    • Oakley, H.1    Cole, S.L.2    Logan, S.3
  • 46
    • 84873708294 scopus 로고    scopus 로고
    • Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer
    • in press
    • Zhou J., Chng W.J. Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer. Mitochondrion 2013, in press, http://dx.doi.org/10.1016/j.mito.2012.06.004.
    • (2013) Mitochondrion
    • Zhou, J.1    Chng, W.J.2
  • 47
    • 33745170043 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in Txnip-deficient mice
    • Sheth S.S., Bodnar J.S., Ghazalpour A., et al. Hepatocellular carcinoma in Txnip-deficient mice. Oncogene 2006, 25:3528-3536.
    • (2006) Oncogene , vol.25 , pp. 3528-3536
    • Sheth, S.S.1    Bodnar, J.S.2    Ghazalpour, A.3
  • 48
    • 77958133863 scopus 로고    scopus 로고
    • 3 up-regulated protein 1 suppresses TNF-α-induced NF-κB activation in hepatocarcinogenesis
    • 3 up-regulated protein 1 suppresses TNF-α-induced NF-κB activation in hepatocarcinogenesis. J. Immunol. 2010, 185:3980-3989.
    • (2010) J. Immunol. , vol.185 , pp. 3980-3989
    • Kwon, H.J.1    Won, Y.S.2    Suh, H.W.3
  • 49
    • 80053165531 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein suppresses bladder carcinogenesis
    • Nishizawa K., Nishiyama H., Matsui Y., et al. Thioredoxin-interacting protein suppresses bladder carcinogenesis. Carcinogenesis 2011, 32:1459-1466.
    • (2011) Carcinogenesis , vol.32 , pp. 1459-1466
    • Nishizawa, K.1    Nishiyama, H.2    Matsui, Y.3
  • 50
    • 34848853584 scopus 로고    scopus 로고
    • Involvement of upregulation of DEPDC1 (DEP domain containing 1) in bladder carcinogenesis
    • Kanehira M., Harada Y., Takata R., et al. Involvement of upregulation of DEPDC1 (DEP domain containing 1) in bladder carcinogenesis. Oncogene 2007, 26:6448-6455.
    • (2007) Oncogene , vol.26 , pp. 6448-6455
    • Kanehira, M.1    Harada, Y.2    Takata, R.3
  • 51
    • 77955018234 scopus 로고    scopus 로고
    • Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells
    • Harada Y., Kanehira M., Fujisawa Y., et al. Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells. Cancer Res. 2010, 70:5829-5839.
    • (2010) Cancer Res. , vol.70 , pp. 5829-5839
    • Harada, Y.1    Kanehira, M.2    Fujisawa, Y.3
  • 52
    • 84855369366 scopus 로고    scopus 로고
    • Identification of genes up-regulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas
    • Okayama H., Kohno T., Ishii Y., et al. Identification of genes up-regulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas. Cancer Res. 2012, 72:100-111.
    • (2012) Cancer Res. , vol.72 , pp. 100-111
    • Okayama, H.1    Kohno, T.2    Ishii, Y.3
  • 53
    • 76549124435 scopus 로고    scopus 로고
    • E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation
    • Deng Q., Wang Q., Zong W.Y., et al. E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation. Cancer Res. 2010, 70:782-791.
    • (2010) Cancer Res. , vol.70 , pp. 782-791
    • Deng, Q.1    Wang, Q.2    Zong, W.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.