메뉴 건너뛰기




Volumn 10, Issue 3, 2008, Pages

Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; EUPATORIN; FLAVONOID; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; UNSPECIFIC MONOOXYGENASE;

EID: 55749110433     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr2090     Document Type: Article
Times cited : (108)

References (32)
  • 1
    • 34548305781 scopus 로고    scopus 로고
    • Breast cancer: trends, risks, treatments and effects
    • Draper L. Breast cancer: trends, risks, treatments and effects. AAOHN J 2006, 54:445-451.
    • (2006) AAOHN J , vol.54 , pp. 445-451
    • Draper, L.1
  • 2
    • 33846781391 scopus 로고    scopus 로고
    • Pharmacogenetics and oncology treatment for breast cancer
    • 10.1517/14656566.8.2.119, 17257083
    • Marsh S, McLeod HL. Pharmacogenetics and oncology treatment for breast cancer. Expert Opin Pharmacother 2007, 8:119-127. 10.1517/14656566.8.2.119, 17257083.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 119-127
    • Marsh, S.1    McLeod, H.L.2
  • 3
    • 33748988463 scopus 로고    scopus 로고
    • Addressing the soy and breast cancer relationship: review, commentary and workshop proceedings
    • Messina M, McCaskill-Stevens W, Lampe JW. Addressing the soy and breast cancer relationship: review, commentary and workshop proceedings. J Natl Cancer Inst 2006, 98:1275-1284.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1275-1284
    • Messina, M.1    McCaskill-Stevens, W.2    Lampe, J.W.3
  • 6
    • 0036637111 scopus 로고    scopus 로고
    • Antiproliferative constituents in plants 10. Flavones from the leaves of Lantana montevidensis Briq. and consideration of structure-activity relationship
    • 10.1248/bpb.25.875, 12132661
    • Nagao T, Abe F, Kinjo J, Okabe H. Antiproliferative constituents in plants 10. Flavones from the leaves of Lantana montevidensis Briq. and consideration of structure-activity relationship. Biol Pharm Bull 2002, 25:875-879. 10.1248/bpb.25.875, 12132661.
    • (2002) Biol Pharm Bull , vol.25 , pp. 875-879
    • Nagao, T.1    Abe, F.2    Kinjo, J.3    Okabe, H.4
  • 8
    • 4444223732 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes: novel options for cancer therapeutics
    • McFadyen MCE, Melvin WT, Murray GI. Cytochrome P450 enzymes: novel options for cancer therapeutics. Mol Cancer Ther 2004, 3:363-371.
    • (2004) Mol Cancer Ther , vol.3 , pp. 363-371
    • McFadyen, M.C.E.1    Melvin, W.T.2    Murray, G.I.3
  • 9
    • 2342429738 scopus 로고    scopus 로고
    • The role of cytochrome P450 in cytotoxic bioactivation: future therapeutic directions
    • 10.2174/1568009043333014, 15134533
    • Rooney PH, Telfer C, McFadyen MC, Melvin WT, Murray GI. The role of cytochrome P450 in cytotoxic bioactivation: future therapeutic directions. Curr Cancer Drug Targets 2004, 4:257-265. 10.2174/1568009043333014, 15134533.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 257-265
    • Rooney, P.H.1    Telfer, C.2    McFadyen, M.C.3    Melvin, W.T.4    Murray, G.I.5
  • 10
    • 18144383865 scopus 로고    scopus 로고
    • Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis
    • 10.1158/0008-5472.CAN-04-3771, 15867368
    • Leung YK, Lau KM, Mobley J, Jiang Z, Ho SM. Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis. Cancer Res 2005, 65:3726-3734. 10.1158/0008-5472.CAN-04-3771, 15867368.
    • (2005) Cancer Res , vol.65 , pp. 3726-3734
    • Leung, Y.K.1    Lau, K.M.2    Mobley, J.3    Jiang, Z.4    Ho, S.M.5
  • 11
    • 0028303823 scopus 로고
    • Cytochrome P450 expression in oesophageal cancer
    • 1374739, 8200549, 10.1136/gut.35.5.599
    • Murray GI, Shaw D, Weaver RJ, McKay JA, Ewen SW, Melvin WT, Burke MD. Cytochrome P450 expression in oesophageal cancer. Gut 1994, 35:599-603. 1374739, 8200549, 10.1136/gut.35.5.599.
    • (1994) Gut , vol.35 , pp. 599-603
    • Murray, G.I.1    Shaw, D.2    Weaver, R.J.3    McKay, J.A.4    Ewen, S.W.5    Melvin, W.T.6    Burke, M.D.7
  • 12
    • 0029956982 scopus 로고    scopus 로고
    • Expression of cytochrome P450s and glutathione S-transferases in human esophagus with squamous cell carcinomas
    • 10.1093/carcin/17.7.1477, 8706252
    • Nakajima T, Wang RS, Nimura Y, Pin YM, He M, Vainio H, Murayama N, Aoyama T, Iida F. Expression of cytochrome P450s and glutathione S-transferases in human esophagus with squamous cell carcinomas. Carcinogenesis 1996, 17:1477-1481. 10.1093/carcin/17.7.1477, 8706252.
    • (1996) Carcinogenesis , vol.17 , pp. 1477-1481
    • Nakajima, T.1    Wang, R.S.2    Nimura, Y.3    Pin, Y.M.4    He, M.5    Vainio, H.6    Murayama, N.7    Aoyama, T.8    Iida, F.9
  • 15
    • 9444263203 scopus 로고    scopus 로고
    • Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolised, and bind to macromolecules in sensitive human cancer cells
    • 10.1124/dmd.104.001057, 15355884
    • Brantley E, Trapani V, Alley MC, Hose CD, Bradshaw TD, Stevens MF, Sausville EA, Stinson SF. Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolised, and bind to macromolecules in sensitive human cancer cells. Drug Metab Dispos 2004, 32:1392-1401. 10.1124/dmd.104.001057, 15355884.
    • (2004) Drug Metab Dispos , vol.32 , pp. 1392-1401
    • Brantley, E.1    Trapani, V.2    Alley, M.C.3    Hose, C.D.4    Bradshaw, T.D.5    Stevens, M.F.6    Sausville, E.A.7    Stinson, S.F.8
  • 16
    • 0036015562 scopus 로고    scopus 로고
    • Tumor cytochrome P450 and drug activation
    • 12052211, 10.2174/1381612023394502
    • Patterson LH, Murray GI. Tumor cytochrome P450 and drug activation. Curr Pharm Des. 2002, 8:1335-1347. 12052211, 10.2174/1381612023394502.
    • (2002) Curr Pharm Des. , vol.8 , pp. 1335-1347
    • Patterson, L.H.1    Murray, G.I.2
  • 18
    • 33746690306 scopus 로고    scopus 로고
    • Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity
    • 10.1016/j.bcp.2006.05.015, 16814747
    • Atherton K, Mutch E, Ford D. Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity. Biochem Pharmacol 2006, 72:624-631. 10.1016/j.bcp.2006.05.015, 16814747.
    • (2006) Biochem Pharmacol , vol.72 , pp. 624-631
    • Atherton, K.1    Mutch, E.2    Ford, D.3
  • 19
    • 27144443044 scopus 로고    scopus 로고
    • Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols
    • 10.1093/carcin/bgi127, 15905203
    • Wen X, Walle T. Preferential induction of CYP1B1 by benzo[a]pyrene in human oral epithelial cells: impact on DNA adduct formation and prevention by polyphenols. Carcinogenesis 2005, 26:1774-1781. 10.1093/carcin/bgi127, 15905203.
    • (2005) Carcinogenesis , vol.26 , pp. 1774-1781
    • Wen, X.1    Walle, T.2
  • 20
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principles of protein-dye binding
    • 10.1016/0003-2697(76)90527-3, 942051
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principles of protein-dye binding. Anal Biochem 1976, 72:248-254. 10.1016/0003-2697(76)90527-3, 942051.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 21
    • 0034599543 scopus 로고    scopus 로고
    • Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1
    • 10.1016/S0300-483X(99)00215-2, 10781868
    • Doostdar H, Burke MD, Mayer RT. Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. Toxicology 2000, 144:31-38. 10.1016/S0300-483X(99)00215-2, 10781868.
    • (2000) Toxicology , vol.144 , pp. 31-38
    • Doostdar, H.1    Burke, M.D.2    Mayer, R.T.3
  • 22
    • 0034665390 scopus 로고    scopus 로고
    • Role of CYP1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells
    • Chua MS, Kashiyama E, Bradshaw TD, Stinson SF, Brantley E, Sausville EA, Stevens MF. Role of CYP1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells. Cancer Res 2000, 60:5196-5203.
    • (2000) Cancer Res , vol.60 , pp. 5196-5203
    • Chua, M.S.1    Kashiyama, E.2    Bradshaw, T.D.3    Stinson, S.F.4    Brantley, E.5    Sausville, E.A.6    Stevens, M.F.7
  • 23
    • 0031426303 scopus 로고    scopus 로고
    • Mechanism of inhibition of MDA-MB 468 breast cancer cell growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • 10.1093/carcin/18.5.925, 9163677
    • Wang WL, Porter W, Burghardt R, Safe SH. Mechanism of inhibition of MDA-MB 468 breast cancer cell growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Carcinogenesis 1997, 18:925-933. 10.1093/carcin/18.5.925, 9163677.
    • (1997) Carcinogenesis , vol.18 , pp. 925-933
    • Wang, W.L.1    Porter, W.2    Burghardt, R.3    Safe, S.H.4
  • 24
    • 0031927210 scopus 로고    scopus 로고
    • Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells
    • 10.1093/carcin/19.2.291, 9498279
    • Spink DC, Spink BC, Cao JQ, DePasquale JA, Pentecost BT, Fasco MJ, Li Y, Sutter TR. Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells. Carcinogenesis 1998, 19:291-298. 10.1093/carcin/19.2.291, 9498279.
    • (1998) Carcinogenesis , vol.19 , pp. 291-298
    • Spink, D.C.1    Spink, B.C.2    Cao, J.Q.3    DePasquale, J.A.4    Pentecost, B.T.5    Fasco, M.J.6    Li, Y.7    Sutter, T.R.8
  • 25
    • 0031694273 scopus 로고    scopus 로고
    • Selectivity of polycyclic inhibitors for human cytochromes P450 1A1, 1A2 and 1B1
    • 10.1021/tx980090+, 9760279
    • Shimada T, Yamazaki H, Foroozesh M, Hopkins NE, Alworth WL, Guengerich FP. Selectivity of polycyclic inhibitors for human cytochromes P450 1A1, 1A2 and 1B1. Chem Res Toxicol 1998, 11:1048-1056. 10.1021/tx980090+, 9760279.
    • (1998) Chem Res Toxicol , vol.11 , pp. 1048-1056
    • Shimada, T.1    Yamazaki, H.2    Foroozesh, M.3    Hopkins, N.E.4    Alworth, W.L.5    Guengerich, F.P.6
  • 27
    • 33745642100 scopus 로고    scopus 로고
    • Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzothiazoles
    • 10.1021/jm060359j, 16789754
    • Vasselin DA, Westwell AD, Matthews CS, Bradshaw TD, Stevens MF. Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzothiazoles. J Med Chem 2006, 49:3973-3981. 10.1021/jm060359j, 16789754.
    • (2006) J Med Chem , vol.49 , pp. 3973-3981
    • Vasselin, D.A.1    Westwell, A.D.2    Matthews, C.S.3    Bradshaw, T.D.4    Stevens, M.F.5
  • 28
    • 0036229022 scopus 로고    scopus 로고
    • In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids
    • 10.1016/S0278-6915(01)00125-9, 11955666
    • Breinholt VM, Offord EA, Brouwer C, Nielsen SE, Brøsen K, Friedberg T. In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids. Food Chem Toxicol 2002, 40:609-616. 10.1016/S0278-6915(01)00125-9, 11955666.
    • (2002) Food Chem Toxicol , vol.40 , pp. 609-616
    • Breinholt, V.M.1    Offord, E.A.2    Brouwer, C.3    Nielsen, S.E.4    Brøsen, K.5    Friedberg, T.6
  • 29
    • 0036146585 scopus 로고    scopus 로고
    • Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2 and CYP2C9
    • 10.1124/dmd.30.2.103, 11792676
    • Otake Y, Walle T. Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2 and CYP2C9. Drug Metab Dispos 2002, 30:103-105. 10.1124/dmd.30.2.103, 11792676.
    • (2002) Drug Metab Dispos , vol.30 , pp. 103-105
    • Otake, Y.1    Walle, T.2
  • 31
    • 13244249141 scopus 로고    scopus 로고
    • G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.)
    • 10.1016/j.canlet.2004.01.012, 15105046
    • Kobayakawa J, Sato-Nishimori F, Moriyasu M, Matsukawa Y. G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.). Cancer Lett 2004, 208:59-64. 10.1016/j.canlet.2004.01.012, 15105046.
    • (2004) Cancer Lett , vol.208 , pp. 59-64
    • Kobayakawa, J.1    Sato-Nishimori, F.2    Moriyasu, M.3    Matsukawa, Y.4
  • 32
    • 33749609344 scopus 로고    scopus 로고
    • Effects of α-substitutions on structure and biological activity of anticancer chalcones
    • 10.1016/j.bmcl.2006.08.065, 16949281
    • Lawrence NJ, Patterson RP, Ooi LL, Cook D, Ducki S. Effects of α-substitutions on structure and biological activity of anticancer chalcones. Bioorg Med Chem Lett 2006, 16:5844-5848. 10.1016/j.bmcl.2006.08.065, 16949281.
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 5844-5848
    • Lawrence, N.J.1    Patterson, R.P.2    Ooi, L.L.3    Cook, D.4    Ducki, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.