Aryl hydrocarbon receptor activation by aminoflavone: New molecular target for renal cancer treatment

International Journal of Oncology

Volumn 41, Issue 1, 2012, Pages 125-134

  Callero, Mariana A ^a   Suárez, Guadalupe V ^a   Luzzani, Gabriela ^a   Itkin, Boris ^b   Nguyen, Binh ^c   Loaiza Perez, Andrea I ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b HOSPITAL JUAN A FERNÁNDEZ   (Argentina)

^c Tigris Pharmaceuticals Inc   (United States)

Author keywords

Apoptosis; Aryl hydrocarbon receptor; Cytochrome P450 1A1; Renal cancer

Indexed keywords

5 AMINO 6,8 DIFLUORO 2 (3 FLUOROPHENYL) 7 METHYL 4H 1 BENZOPYRAN 4 ONE; AFP 464; ALPHA NAPHTHOFLAVONE; AMINOFLAVONE; ANTINEOPLASTIC AGENT; AROMATIC HYDROCARBON RECEPTOR; CASPASE 3; CYTOCHROME P450 1A1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NSC 710464; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INDUCTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; KIDNEY CANCER; MOLECULARLY TARGETED THERAPY; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ARYL HYDROCARBON HYDROXYLASES; CARCINOMA, PAPILLARY; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CYTOCHROME P-450 CYP1A1; FLAVONOIDS; GENES, REPORTER; HUMANS; KIDNEY NEOPLASMS; LUCIFERASES; MOLECULAR TARGETED THERAPY; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; TRANSCRIPTIONAL ACTIVATION;

EID: 84862845975     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1427     Document Type: Article

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