메뉴 건너뛰기




Volumn 50, Issue 2, 2014, Pages 559-573

Roles for the TGFβ Superfamily in the Development and Survival of Midbrain Dopaminergic Neurons

Author keywords

BMP family; Development; Midbrain dopaminergic neurons; Neurogenesis; TGF superfamily

Indexed keywords

ACTIVIN; ARTEMIN; BONE MORPHOGENETIC PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GROWTH DIFFERENTIATION FACTOR; GROWTH DIFFERENTIATION FACTOR 5; NEUROTROPHIC FACTOR; NEURTURIN; PERSEPHIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; NERVE GROWTH FACTOR;

EID: 84911002300     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8639-3     Document Type: Review
Times cited : (29)

References (190)
  • 1
    • 34848896595 scopus 로고    scopus 로고
    • Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells
    • PID: 17670789, COI: 1:CAS:528:DC%2BD2sXhtFKqs7zN
    • Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, Kumai M, Hamaguchi A, Nishimura M, Inoue Y, Hayashi H, Takahashi J, Imai T (2007) Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development 134(17):3213–3225
    • (2007) Development , vol.134 , Issue.17 , pp. 3213-3225
    • Ono, Y.1    Nakatani, T.2    Sakamoto, Y.3    Mizuhara, E.4    Minaki, Y.5    Kumai, M.6    Hamaguchi, A.7    Nishimura, M.8    Inoue, Y.9    Hayashi, H.10    Takahashi, J.11    Imai, T.12
  • 2
    • 0001989283 scopus 로고
    • Evidence for the existence of monoamine-containing neurons in the central nervous system. I. demonstration of monoamines in the cell bodies of brain stem neurons
    • Dahlstroem A, Fuxe K (1964) Evidence for the existence of monoamine-containing neurons in the central nervous system. I. demonstration of monoamines in the cell bodies of brain stem neurons. Acta Physiol Scand Suppl 232:231–255
    • (1964) Acta Physiol Scand Suppl , vol.232 , pp. 231-255
    • Dahlstroem, A.1    Fuxe, K.2
  • 3
    • 34247469020 scopus 로고    scopus 로고
    • Dopamine neuron systems in the brain: an update
    • PID: 17408759
    • Bjorklund A, Dunnett SB (2007) Dopamine neuron systems in the brain: an update. Trends Neurosci 30(5):194–202
    • (2007) Trends Neurosci , vol.30 , Issue.5 , pp. 194-202
    • Bjorklund, A.1    Dunnett, S.B.2
  • 4
    • 48349136909 scopus 로고    scopus 로고
    • Progress in Parkinson’s disease—where do we stand?
    • PID: 18582530
    • Toulouse A, Sullivan AM (2008) Progress in Parkinson’s disease—where do we stand? Prog Neurobiol 85(4):376–392
    • (2008) Prog Neurobiol , vol.85 , Issue.4 , pp. 376-392
    • Toulouse, A.1    Sullivan, A.M.2
  • 5
    • 66949152096 scopus 로고    scopus 로고
    • Parkinson’s disease
    • PID: 19524782, COI: 1:CAS:528:DC%2BD1MXnt1ans7w%3D
    • Lees AJ, Hardy J, Revesz T (2009) Parkinson’s disease. Lancet 373(9680):2055–2066
    • (2009) Lancet , vol.373 , Issue.9680 , pp. 2055-2066
    • Lees, A.J.1    Hardy, J.2    Revesz, T.3
  • 7
    • 0027305458 scopus 로고
    • The neural basis of drug craving: an incentive-sensitization theory of addiction
    • PID: 8401595, COI: 1:CAS:528:DyaK3sXlsFWnu78%3D
    • Robinson TE, Berridge KC (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev 18(3):247–291
    • (1993) Brain Res Brain Res Rev , vol.18 , Issue.3 , pp. 247-291
    • Robinson, T.E.1    Berridge, K.C.2
  • 8
    • 33745919520 scopus 로고    scopus 로고
    • Epidemiology of Parkinson’s disease
    • PID: 16713924
    • de Lau LM, Breteler MM (2006) Epidemiology of Parkinson’s disease. Lancet Neurol 5(6):525–535
    • (2006) Lancet Neurol , vol.5 , Issue.6 , pp. 525-535
    • de Lau, L.M.1    Breteler, M.M.2
  • 9
    • 80052337005 scopus 로고    scopus 로고
    • Neurotrophic factors for the treatment of Parkinson’s disease
    • Sullivan AM, Toulouse A (2011) Neurotrophic factors for the treatment of Parkinson’s disease. Cytokine Growth Factor Rev 22(3):157–165
    • (2011) Cytokine Growth Factor Rev , vol.22 , Issue.3 , pp. 157-165
    • Sullivan, A.M.1    Toulouse, A.2
  • 10
    • 41249088472 scopus 로고    scopus 로고
    • Treatment of Parkinson's disease with trophic factors
    • PID: 18394569, COI: 1:CAS:528:DC%2BD1cXmtFOltbo%3D
    • Peterson AL, Nutt JG (2008) Treatment of Parkinson's disease with trophic factors. Neurotherapeutics 5(2):270–280
    • (2008) Neurotherapeutics , vol.5 , Issue.2 , pp. 270-280
    • Peterson, A.L.1    Nutt, J.G.2
  • 11
    • 0033773180 scopus 로고    scopus 로고
    • The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions
    • PID: 11080174, COI: 1:CAS:528:DC%2BD3cXotFKgtb0%3D
    • Bottner M, Krieglstein K, Unsicker K (2000) The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions. J Neurochem 75(6):2227–2240
    • (2000) J Neurochem , vol.75 , Issue.6 , pp. 2227-2240
    • Bottner, M.1    Krieglstein, K.2    Unsicker, K.3
  • 12
    • 20044376614 scopus 로고    scopus 로고
    • The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson’s disease treatment
    • PID: 16185246, COI: 1:CAS:528:DC%2BD2MXhtFSnsb%2FF
    • Sullivan AM, O’Keeffe GW (2005) The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson’s disease treatment. J Anat 207(3):219–226
    • (2005) J Anat , vol.207 , Issue.3 , pp. 219-226
    • Sullivan, A.M.1    O’Keeffe, G.W.2
  • 13
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGF-beta/Smad signaling system
    • PID: 10775259, COI: 1:CAS:528:DC%2BD3cXivVKlsbo%3D
    • Massague J, Wotton D (2000) Transcriptional control by the TGF-beta/Smad signaling system. EMBO J 19(8):1745–1754
    • (2000) EMBO J , vol.19 , Issue.8 , pp. 1745-1754
    • Massague, J.1    Wotton, D.2
  • 14
    • 0030461022 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptors
    • PID: 8968021, COI: 1:CAS:528:DyaK2sXpt1Wksw%3D%3D
    • Yamashita H, Ten Dijke P, Heldin CH, Miyazono K (1996) Bone morphogenetic protein receptors. Bone 19(6):569–574
    • (1996) Bone , vol.19 , Issue.6 , pp. 569-574
    • Yamashita, H.1    Ten Dijke, P.2    Heldin, C.H.3    Miyazono, K.4
  • 15
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • PID: 12809600, COI: 1:CAS:528:DC%2BD3sXkvVekt7o%3D
    • Shi Y, Massague J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113(6):685–700
    • (2003) Cell , vol.113 , Issue.6 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 16
    • 0346996450 scopus 로고    scopus 로고
    • Signal transduction of bone morphogenetic protein receptors
    • PID: 14687659, COI: 1:CAS:528:DC%2BD3sXpvVaisL0%3D
    • Nohe A, Keating E, Knaus P, Petersen NO (2004) Signal transduction of bone morphogenetic protein receptors. Cell Signal 16(3):291–299
    • (2004) Cell Signal , vol.16 , Issue.3 , pp. 291-299
    • Nohe, A.1    Keating, E.2    Knaus, P.3    Petersen, N.O.4
  • 17
    • 79151473137 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: a critical review
    • PID: 20959140, COI: 1:CAS:528:DC%2BC3MXht1yrtbw%3D
    • Bragdon B, Moseychuk O, Saldanha S, King D, Julian J, Nohe A (2011) Bone morphogenetic proteins: a critical review. Cell Signal 23(4):609–620
    • (2011) Cell Signal , vol.23 , Issue.4 , pp. 609-620
    • Bragdon, B.1    Moseychuk, O.2    Saldanha, S.3    King, D.4    Julian, J.5    Nohe, A.6
  • 18
    • 70649083092 scopus 로고    scopus 로고
    • Recent advances in BMP receptor signaling
    • PID: 19897402, COI: 1:CAS:528:DC%2BD1MXhsV2ms7fK
    • Sieber C, Kopf J, Hiepen C, Knaus P (2009) Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev 20(5–6):343–355
    • (2009) Cytokine Growth Factor Rev , vol.20 , Issue.5-6 , pp. 343-355
    • Sieber, C.1    Kopf, J.2    Hiepen, C.3    Knaus, P.4
  • 19
    • 0035032914 scopus 로고    scopus 로고
    • Divergence and convergence of TGF-beta/BMP signaling
    • PID: 11319750, COI: 1:CAS:528:DC%2BD3MXjtF2isbk%3D
    • Miyazono K, Kusanagi K, Inoue H (2001) Divergence and convergence of TGF-beta/BMP signaling. J Cell Physiol 187(3):265–276
    • (2001) J Cell Physiol , vol.187 , Issue.3 , pp. 265-276
    • Miyazono, K.1    Kusanagi, K.2    Inoue, H.3
  • 20
    • 84866742560 scopus 로고    scopus 로고
    • TGFbeta signalling in context
    • PID: 22992590, COI: 1:CAS:528:DC%2BC38XhtlKrs73I
    • Massague J (2012) TGFbeta signalling in context. Nat Rev Mol Cell Biol 13(10):616–630
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.10 , pp. 616-630
    • Massague, J.1
  • 21
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-beta signal transduction
    • PID: 11792802, COI: 1:CAS:528:DC%2BD38XnvFKmtw%3D%3D
    • Moustakas A, Souchelnytskyi S, Heldin CH (2001) Smad regulation in TGF-beta signal transduction. J Cell Sci 114(Pt 24):4359–4369
    • (2001) J Cell Sci , vol.114 , pp. 4359-4369
    • Moustakas, A.1    Souchelnytskyi, S.2    Heldin, C.H.3
  • 22
    • 0141428794 scopus 로고    scopus 로고
    • Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways
    • PID: 14522471, COI: 1:CAS:528:DC%2BD3sXns12mtbs%3D
    • Goumans MJ, Lebrin F, Valdimarsdottir G (2003) Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways. Trends Cardiovasc Med 13(7):301–307
    • (2003) Trends Cardiovasc Med , vol.13 , Issue.7 , pp. 301-307
    • Goumans, M.J.1    Lebrin, F.2    Valdimarsdottir, G.3
  • 23
    • 0034533657 scopus 로고    scopus 로고
    • Signaling of transforming growth factor-beta family members through Smad proteins
    • PID: 11106403, COI: 1:CAS:528:DC%2BD3MXis1Kntg%3D%3D
    • Itoh S, Itoh F, Goumans MJ, Ten Dijke P (2000) Signaling of transforming growth factor-beta family members through Smad proteins. Eur J Biochem 267(24):6954–6967
    • (2000) Eur J Biochem , vol.267 , Issue.24 , pp. 6954-6967
    • Itoh, S.1    Itoh, F.2    Goumans, M.J.3    Ten Dijke, P.4
  • 24
    • 0036910425 scopus 로고    scopus 로고
    • Two major Smad pathways in TGF-beta superfamily signalling
    • PID: 12485160, COI: 1:CAS:528:DC%2BD3sXhtV2htg%3D%3D
    • Miyazawa K, Shinozaki M, Hara T, Furuya T, Miyazono K (2002) Two major Smad pathways in TGF-beta superfamily signalling. Genes Cells 7(12):1191–1204
    • (2002) Genes Cells , vol.7 , Issue.12 , pp. 1191-1204
    • Miyazawa, K.1    Shinozaki, M.2    Hara, T.3    Furuya, T.4    Miyazono, K.5
  • 25
    • 21344455768 scopus 로고    scopus 로고
    • BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk
    • PID: 15871923, COI: 1:CAS:528:DC%2BD2MXlsl2rtL0%3D
    • Miyazono K, Maeda S, Imamura T (2005) BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev 16(3):251–263
    • (2005) Cytokine Growth Factor Rev , vol.16 , Issue.3 , pp. 251-263
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 26
    • 0027285510 scopus 로고
    • GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • PID: 8493557, COI: 1:CAS:528:DyaK2cXks1Gguw%3D%3D
    • Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260(5111):1130–1132
    • (1993) Science , vol.260 , Issue.5111 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 27
    • 0028986656 scopus 로고
    • TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP + toxicity
    • PID: 7882977, COI: 1:CAS:528:DyaK2MXktF2ms7g%3D
    • Krieglstein K, Suter-Crazzolara C, Fischer WH, Unsicker K (1995) TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP + toxicity. EMBO J 14(4):736–742
    • (1995) EMBO J , vol.14 , Issue.4 , pp. 736-742
    • Krieglstein, K.1    Suter-Crazzolara, C.2    Fischer, W.H.3    Unsicker, K.4
  • 28
    • 0033927161 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor stimulates the morphological differentiation of cultured ventral mesencephalic calbindin- and calretinin-expressing neurons
    • PID: 10877917, COI: 1:CAS:528:DC%2BD3cXksVaqsL0%3D
    • Widmer HR, Schaller B, Meyer M, Seiler RW (2000) Glial cell line-derived neurotrophic factor stimulates the morphological differentiation of cultured ventral mesencephalic calbindin- and calretinin-expressing neurons. Exp Neurol 164(1):71–81
    • (2000) Exp Neurol , vol.164 , Issue.1 , pp. 71-81
    • Widmer, H.R.1    Schaller, B.2    Meyer, M.3    Seiler, R.W.4
  • 29
    • 0029552813 scopus 로고
    • GDNF reduces apoptosis in dopaminergic neurons in vitro
    • PID: 8742438, COI: 1:CAS:528:DyaK28XitVygtrs%3D
    • Clarkson ED, Zawada WM, Freed CR (1995) GDNF reduces apoptosis in dopaminergic neurons in vitro. Neuroreport 7(1):145–149
    • (1995) Neuroreport , vol.7 , Issue.1 , pp. 145-149
    • Clarkson, E.D.1    Zawada, W.M.2    Freed, C.R.3
  • 30
    • 0030740377 scopus 로고    scopus 로고
    • GDNF improves survival and reduces apoptosis in human embryonic dopaminergic neurons in vitro
    • PID: 9211823, COI: 1:CAS:528:DyaK2sXltFersbo%3D
    • Clarkson ED, Zawada WM, Freed CR (1997) GDNF improves survival and reduces apoptosis in human embryonic dopaminergic neurons in vitro. Cell Tissue Res 289(2):207–210
    • (1997) Cell Tissue Res , vol.289 , Issue.2 , pp. 207-210
    • Clarkson, E.D.1    Zawada, W.M.2    Freed, C.R.3
  • 31
    • 0033962594 scopus 로고    scopus 로고
    • Neuroprotective mechanism of glial cell line-derived neurotrophic factor in mesencephalic neurons
    • PID: 10693950, COI: 1:CAS:528:DC%2BD3cXhtlChsbs%3D
    • Sawada H, Ibi M, Kihara T, Urushitani M, Nakanishi M, Akaike A, Shimohama S (2000) Neuroprotective mechanism of glial cell line-derived neurotrophic factor in mesencephalic neurons. J Neurochem 74(3):1175–1184
    • (2000) J Neurochem , vol.74 , Issue.3 , pp. 1175-1184
    • Sawada, H.1    Ibi, M.2    Kihara, T.3    Urushitani, M.4    Nakanishi, M.5    Akaike, A.6    Shimohama, S.7
  • 32
    • 84876539226 scopus 로고    scopus 로고
    • Calcitriol imparts neuroprotection in vitro to midbrain dopaminergic neurons by upregulating GDNF expression
    • PID: 23626767, COI: 1:CAS:528:DC%2BC3sXntVKqsbY%3D
    • Orme RP, Bhangal MS, Fricker RA (2013) Calcitriol imparts neuroprotection in vitro to midbrain dopaminergic neurons by upregulating GDNF expression. PLoS One 8(4):e62040
    • (2013) PLoS One , vol.8 , Issue.4 , pp. e62040
    • Orme, R.P.1    Bhangal, M.S.2    Fricker, R.A.3
  • 33
    • 34347269143 scopus 로고    scopus 로고
    • Differential effects of glial cell line-derived neurotrophic factor on A9 and A10 dopamine neuron survival in vitro
    • PID: 17583436, COI: 1:CAS:528:DC%2BD2sXntFygtLY%3D
    • Borgal L, Hong M, Sadi D, Mendez I (2007) Differential effects of glial cell line-derived neurotrophic factor on A9 and A10 dopamine neuron survival in vitro. Neuroscience 147(3):712–719
    • (2007) Neuroscience , vol.147 , Issue.3 , pp. 712-719
    • Borgal, L.1    Hong, M.2    Sadi, D.3    Mendez, I.4
  • 34
    • 0031905828 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor improves intrastriatal graft survival of stored dopaminergic cells
    • PID: 9460746, COI: 1:CAS:528:DyaK1cXjslSlsg%3D%3D
    • Apostolides C, Sanford E, Hong M, Mendez I (1998) Glial cell line-derived neurotrophic factor improves intrastriatal graft survival of stored dopaminergic cells. Neuroscience 83(2):363–372
    • (1998) Neuroscience , vol.83 , Issue.2 , pp. 363-372
    • Apostolides, C.1    Sanford, E.2    Hong, M.3    Mendez, I.4
  • 35
    • 0033949290 scopus 로고    scopus 로고
    • Increased survival of dopaminergic neurons in striatal grafts of fetal ventral mesencephalic cells exposed to neurotrophin-3 or glial cell line-derived neurotrophic factor
    • PID: 10784066, COI: 1:STN:280:DC%2BD3c3ksVKmsA%3D%3D
    • Espejo M, Cutillas B, Arenas TE, Ambrosio S (2000) Increased survival of dopaminergic neurons in striatal grafts of fetal ventral mesencephalic cells exposed to neurotrophin-3 or glial cell line-derived neurotrophic factor. Cell Transplant 9(1):45–53
    • (2000) Cell Transplant , vol.9 , Issue.1 , pp. 45-53
    • Espejo, M.1    Cutillas, B.2    Arenas, T.E.3    Ambrosio, S.4
  • 36
    • 8544253929 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor improves survival of ventral mesencephalic grafts to the 6-hydroxydopamine lesioned striatum
    • PID: 9305812, COI: 1:CAS:528:DyaK2sXltlaisLg%3D
    • Granholm AC, Mott JL, Bowenkamp K, Eken S, Henry S, Hoffer BJ, Lapchak PA, Palmer MR, van Horne C, Gerhardt GA (1997) Glial cell line-derived neurotrophic factor improves survival of ventral mesencephalic grafts to the 6-hydroxydopamine lesioned striatum. Exp Brain Res 116(1):29–38
    • (1997) Exp Brain Res , vol.116 , Issue.1 , pp. 29-38
    • Granholm, A.C.1    Mott, J.L.2    Bowenkamp, K.3    Eken, S.4    Henry, S.5    Hoffer, B.J.6    Lapchak, P.A.7    Palmer, M.R.8    van Horne, C.9    Gerhardt, G.A.10
  • 37
    • 0032192007 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue
    • PID: 9784279, COI: 1:CAS:528:DyaK1cXnsVWqsrw%3D
    • Yurek DM (1998) Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue. Exp Neurol 153(2):195–202
    • (1998) Exp Neurol , vol.153 , Issue.2 , pp. 195-202
    • Yurek, D.M.1
  • 38
    • 0032457981 scopus 로고    scopus 로고
    • Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease
    • Sullivan AM, Pohl J, Blunt SB (1998) Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease. Eur J Neurosci 10(12):3681–3688
    • (1998) Eur J Neurosci , vol.10 , Issue.12 , pp. 3681-3688
    • Sullivan, A.M.1    Pohl, J.2    Blunt, S.B.3
  • 39
    • 0037713538 scopus 로고    scopus 로고
    • Postnatal developmental programmed cell death in dopamine neurons
    • PID: 12846975, COI: 1:CAS:528:DC%2BD3sXmtVCkurs%3D
    • Burke RE (2003) Postnatal developmental programmed cell death in dopamine neurons. Ann N Y Acad Sci 991:69–79
    • (2003) Ann N Y Acad Sci , vol.991 , pp. 69-79
    • Burke, R.E.1
  • 40
    • 1642546572 scopus 로고    scopus 로고
    • Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets
    • PID: 15044553, COI: 1:CAS:528:DC%2BD2cXjtFWmsL4%3D
    • Kholodilov N, Yarygina O, Oo TF, Zhang H, Sulzer D, Dauer W, Burke RE (2004) Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets. J Neurosci 24(12):3136–3146
    • (2004) J Neurosci , vol.24 , Issue.12 , pp. 3136-3146
    • Kholodilov, N.1    Yarygina, O.2    Oo, T.F.3    Zhang, H.4    Sulzer, D.5    Dauer, W.6    Burke, R.E.7
  • 41
    • 0034192597 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons
    • PID: 10777782, COI: 1:CAS:528:DC%2BD3cXivFKht7g%3D
    • Granholm AC, Reyland M, Albeck D, Sanders L, Gerhardt G, Hoernig G, Shen L, Westphal H, Hoffer B (2000) Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons. J Neurosci 20(9):3182–3190
    • (2000) J Neurosci , vol.20 , Issue.9 , pp. 3182-3190
    • Granholm, A.C.1    Reyland, M.2    Albeck, D.3    Sanders, L.4    Gerhardt, G.5    Hoernig, G.6    Shen, L.7    Westphal, H.8    Hoffer, B.9
  • 42
    • 0028912424 scopus 로고
    • Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat
    • PID: 7781171, COI: 1:CAS:528:DyaK2MXkvFWltbk%3D
    • Choi-Lundberg DL, Bohn MC (1995) Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Brain Res Dev Brain Res 85(1):80–88
    • (1995) Brain Res Dev Brain Res , vol.85 , Issue.1 , pp. 80-88
    • Choi-Lundberg, D.L.1    Bohn, M.C.2
  • 43
    • 84892643401 scopus 로고    scopus 로고
    • Sullivan AM (2013) 6-Hydroxydopamine induces distinct alterations in GDF5 and GDNF mRNA expression in the rat nigrostriatal system in vivo
    • Gavin AM, Walsh S, Wyatt SL, O’Keeffe GW, Sullivan AM (2013) 6-Hydroxydopamine induces distinct alterations in GDF5 and GDNF mRNA expression in the rat nigrostriatal system in vivo. Neurosci Lett 561:176–181
    • Neurosci Lett , vol.561 , pp. 176-181
    • Gavin, A.M.1    Walsh, S.2    Wyatt, S.L.3    O’Keeffe, G.W.4
  • 44
    • 84876133967 scopus 로고    scopus 로고
    • Dopamine D2 receptor activation leads to an up-regulation of glial cell line-derived neurotrophic factor via Gbetagamma-Erk1/2-dependent induction of Zif268
    • Ahmadiantehrani S, Ron D (2013) Dopamine D2 receptor activation leads to an up-regulation of glial cell line-derived neurotrophic factor via Gbetagamma-Erk1/2-dependent induction of Zif268. J Neurochem 125(2):193–204
    • (2013) J Neurochem , vol.125 , Issue.2 , pp. 193-204
    • Ahmadiantehrani, S.1    Ron, D.2
  • 45
    • 0033575432 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor protects dopaminergic neurons from 6-hydroxydopamine toxicity in vitro
    • PID: 10454161, COI: 1:CAS:528:DyaK1MXktVGqu78%3D
    • Eggert K, Schlegel J, Oertel W, Wurz C, Krieg JC, Vedder H (1999) Glial cell line-derived neurotrophic factor protects dopaminergic neurons from 6-hydroxydopamine toxicity in vitro. Neurosci Lett 269(3):178–182
    • (1999) Neurosci Lett , vol.269 , Issue.3 , pp. 178-182
    • Eggert, K.1    Schlegel, J.2    Oertel, W.3    Wurz, C.4    Krieg, J.C.5    Vedder, H.6
  • 46
    • 0030031116 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium
    • PID: 8522992, COI: 1:CAS:528:DyaK2MXhtVSns7rL
    • Hou JG, Lin LF, Mytilineou C (1996) Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium. J Neurochem 66(1):74–82
    • (1996) J Neurochem , vol.66 , Issue.1 , pp. 74-82
    • Hou, J.G.1    Lin, L.F.2    Mytilineou, C.3
  • 47
    • 0028834063 scopus 로고
    • Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
    • PID: 7830766, COI: 1:CAS:528:DyaK2MXjtlygtbc%3D
    • Tomac A, Lindqvist E, Lin LF, Ogren SO, Young D, Hoffer BJ, Olson L (1995) Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373(6512):335–339
    • (1995) Nature , vol.373 , Issue.6512 , pp. 335-339
    • Tomac, A.1    Lindqvist, E.2    Lin, L.F.3    Ogren, S.O.4    Young, D.5    Hoffer, B.J.6    Olson, L.7
  • 49
    • 0035004246 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration
    • PID: 11312561, COI: 1:CAS:528:DC%2BD3MXivVeiurg%3D
    • Connor B, Kozlowski DA, Unnerstall JR, Elsworth JD, Tillerson JL, Schallert T, Bohn MC (2001) Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration. Exp Neurol 169(1):83–95
    • (2001) Exp Neurol , vol.169 , Issue.1 , pp. 83-95
    • Connor, B.1    Kozlowski, D.A.2    Unnerstall, J.R.3    Elsworth, J.D.4    Tillerson, J.L.5    Schallert, T.6    Bohn, M.C.7
  • 50
    • 0033767704 scopus 로고    scopus 로고
    • Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections
    • PID: 11031079, COI: 1:CAS:528:DC%2BD3cXnt1WjsLg%3D
    • Kozlowski DA, Connor B, Tillerson JL, Schallert T, Bohn MC (2000) Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections. Exp Neurol 166(1):1–15
    • (2000) Exp Neurol , vol.166 , Issue.1 , pp. 1-15
    • Kozlowski, D.A.1    Connor, B.2    Tillerson, J.L.3    Schallert, T.4    Bohn, M.C.5
  • 51
    • 0032514206 scopus 로고    scopus 로고
    • GDNF administration induces recovery of the nigrostriatal dopaminergic system both in young and aged parkinsonian mice
    • PID: 9694229, COI: 1:CAS:528:DyaK1cXltVKlt7k%3D
    • Date I, Aoi M, Tomita S, Collins F, Ohmoto T (1998) GDNF administration induces recovery of the nigrostriatal dopaminergic system both in young and aged parkinsonian mice. Neuroreport 9(10):2365–2369
    • (1998) Neuroreport , vol.9 , Issue.10 , pp. 2365-2369
    • Date, I.1    Aoi, M.2    Tomita, S.3    Collins, F.4    Ohmoto, T.5
  • 53
    • 0035970762 scopus 로고    scopus 로고
    • Neuroprotective effects of GDNF against 6-OHDA in young and aged rats
    • PID: 11277973, COI: 1:CAS:528:DC%2BD3MXitF2rsbk%3D
    • Fox CM, Gash DM, Smoot MK, Cass WA (2001) Neuroprotective effects of GDNF against 6-OHDA in young and aged rats. Brain Res 896(1–2):56–63
    • (2001) Brain Res , vol.896 , Issue.1-2 , pp. 56-63
    • Fox, C.M.1    Gash, D.M.2    Smoot, M.K.3    Cass, W.A.4
  • 54
    • 42249112992 scopus 로고    scopus 로고
    • Getting connected in the dopamine system
    • PID: 18304718
    • Van den Heuvel DM, Pasterkamp RJ (2008) Getting connected in the dopamine system. Prog Neurobiol 85(1):75–93
    • (2008) Prog Neurobiol , vol.85 , Issue.1 , pp. 75-93
    • Van den Heuvel, D.M.1    Pasterkamp, R.J.2
  • 56
    • 14844311296 scopus 로고    scopus 로고
    • Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
    • PID: 15739547, COI: 1:CAS:528:DC%2BD2MXhslygs7s%3D
    • Slevin JT, Gerhardt GA, Smith CD, Gash DM, Kryscio R, Young B (2005) Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 102(2):216–222
    • (2005) J Neurosurg , vol.102 , Issue.2 , pp. 216-222
    • Slevin, J.T.1    Gerhardt, G.A.2    Smith, C.D.3    Gash, D.M.4    Kryscio, R.5    Young, B.6
  • 58
    • 77955662358 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity
    • PID: 20471698, COI: 1:CAS:528:DC%2BC3cXhtVKhu7zJ
    • Xing B, Xin T, Zhao L, Hunter RL, Chen Y, Bing G (2010) Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity. J Neuroimmunol 225(1–2):43–51
    • (2010) J Neuroimmunol , vol.225 , Issue.1-2 , pp. 43-51
    • Xing, B.1    Xin, T.2    Zhao, L.3    Hunter, R.L.4    Chen, Y.5    Bing, G.6
  • 59
    • 84859107546 scopus 로고    scopus 로고
    • Contributions of central and systemic inflammation to the pathophysiology of Parkinson’s disease
    • PID: 22361232, COI: 1:CAS:528:DC%2BC38XjtF2itb4%3D
    • Collins LM, Toulouse A, Connor TJ, Nolan YM (2012) Contributions of central and systemic inflammation to the pathophysiology of Parkinson’s disease. Neuropharmacology 62(7):2154–2168
    • (2012) Neuropharmacology , vol.62 , Issue.7 , pp. 2154-2168
    • Collins, L.M.1    Toulouse, A.2    Connor, T.J.3    Nolan, Y.M.4
  • 60
    • 84875243183 scopus 로고    scopus 로고
    • Parkinson’s disease in the nuclear age of neuroinflammation
    • PID: 23318001, COI: 1:CAS:528:DC%2BC3sXjsFygsLs%3D
    • Nolan YM, Sullivan AM, Toulouse A (2013) Parkinson’s disease in the nuclear age of neuroinflammation. Trends Mol Med 19(3):187–196
    • (2013) Trends Mol Med , vol.19 , Issue.3 , pp. 187-196
    • Nolan, Y.M.1    Sullivan, A.M.2    Toulouse, A.3
  • 61
    • 84858667311 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson’s disease
    • PID: 22166438
    • Hirsch EC, Vyas S, Hunot S (2012) Neuroinflammation in Parkinson’s disease. Parkinsonism Relat Disord 18(Suppl 1):S210–S212
    • (2012) Parkinsonism Relat Disord , vol.18 , pp. S210-S212
    • Hirsch, E.C.1    Vyas, S.2    Hunot, S.3
  • 62
    • 84878867659 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development
    • PID: 23603197, COI: 1:CAS:528:DC%2BC3sXnsVGntL0%3D
    • Hegarty SV, Sullivan AM, O’Keeffe GW (2013) Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development. Dev Biol 379(2):123–138
    • (2013) Dev Biol , vol.379 , Issue.2 , pp. 123-138
    • Hegarty, S.V.1    Sullivan, A.M.2    O’Keeffe, G.W.3
  • 63
    • 80052173590 scopus 로고    scopus 로고
    • Signaling of glial cell line-derived neurotrophic factor and its receptor GFRalpha1 induce Nurr1 and Pitx3 to promote survival of grafted midbrain-derived neural stem cells in a rat model of Parkinson disease
    • PID: 21865882, COI: 1:CAS:528:DC%2BC3MXhtV2itbnE
    • Lei Z, Jiang Y, Li T, Zhu J, Zeng S (2011) Signaling of glial cell line-derived neurotrophic factor and its receptor GFRalpha1 induce Nurr1 and Pitx3 to promote survival of grafted midbrain-derived neural stem cells in a rat model of Parkinson disease. J Neuropathol Exp Neurol 70(9):736–747
    • (2011) J Neuropathol Exp Neurol , vol.70 , Issue.9 , pp. 736-747
    • Lei, Z.1    Jiang, Y.2    Li, T.3    Zhu, J.4    Zeng, S.5
  • 64
    • 2342533103 scopus 로고    scopus 로고
    • GDNF promotes neuronal differentiation and dopaminergic development of mouse mesencephalic neurospheres
    • PID: 15135891, COI: 1:CAS:528:DC%2BD2cXjvVGlsbk%3D
    • Roussa E, Krieglstein K (2004) GDNF promotes neuronal differentiation and dopaminergic development of mouse mesencephalic neurospheres. Neurosci Lett 361(1–3):52–55
    • (2004) Neurosci Lett , vol.361 , Issue.1-3 , pp. 52-55
    • Roussa, E.1    Krieglstein, K.2
  • 65
    • 80052585299 scopus 로고    scopus 로고
    • Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons
    • PID: 21900559, COI: 1:CAS:528:DC%2BC3MXhtFOhtrzJ
    • Peng C, Aron L, Klein R, Li M, Wurst W, Prakash N, Le W (2011) Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons. J Neurosci 31(36):12802–12815
    • (2011) J Neurosci , vol.31 , Issue.36 , pp. 12802-12815
    • Peng, C.1    Aron, L.2    Klein, R.3    Li, M.4    Wurst, W.5    Prakash, N.6    Le, W.7
  • 66
    • 1642363250 scopus 로고    scopus 로고
    • Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3
    • PID: 14973278, COI: 1:CAS:528:DC%2BD2cXis1emsrc%3D
    • Smidt MP, Smits SM, Bouwmeester H, Hamers FP, van der Linden AJ, Hellemons AJ, Graw J, Burbach JP (2004) Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3. Development 131(5):1145–1155
    • (2004) Development , vol.131 , Issue.5 , pp. 1145-1155
    • Smidt, M.P.1    Smits, S.M.2    Bouwmeester, H.3    Hamers, F.P.4    van der Linden, A.J.5    Hellemons, A.J.6    Graw, J.7    Burbach, J.P.8
  • 67
    • 0037390135 scopus 로고    scopus 로고
    • Pitx3 is required for development of substantia nigra dopaminergic neurons
    • PID: 12655058, COI: 1:CAS:528:DC%2BD3sXivFWjsL8%3D
    • Nunes I, Tovmasian LT, Silva RM, Burke RE, Goff SP (2003) Pitx3 is required for development of substantia nigra dopaminergic neurons. Proc Natl Acad Sci U S A 100(7):4245–4250
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.7 , pp. 4245-4250
    • Nunes, I.1    Tovmasian, L.T.2    Silva, R.M.3    Burke, R.E.4    Goff, S.P.5
  • 68
    • 0037786542 scopus 로고    scopus 로고
    • Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice
    • PID: 12829322, COI: 1:CAS:528:DC%2BD3sXkvVCltr0%3D
    • Hwang DY, Ardayfio P, Kang UJ, Semina EV, Kim KS (2003) Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice. Brain Res Mol Brain Res 114(2):123–131
    • (2003) Brain Res Mol Brain Res , vol.114 , Issue.2 , pp. 123-131
    • Hwang, D.Y.1    Ardayfio, P.2    Kang, U.J.3    Semina, E.V.4    Kim, K.S.5
  • 70
    • 0031805754 scopus 로고    scopus 로고
    • Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene
    • PID: 9608532, COI: 1:CAS:528:DyaK1cXjsFWgsbk%3D
    • Castillo SO, Baffi JS, Palkovits M, Goldstein DS, Kopin IJ, Witta J, Magnuson MA, Nikodem VM (1998) Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Mol Cell Neurosci 11(1–2):36–46
    • (1998) Mol Cell Neurosci , vol.11 , Issue.1-2 , pp. 36-46
    • Castillo, S.O.1    Baffi, J.S.2    Palkovits, M.3    Goldstein, D.S.4    Kopin, I.J.5    Witta, J.6    Magnuson, M.A.7    Nikodem, V.M.8
  • 71
    • 0035971910 scopus 로고    scopus 로고
    • Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain-derived neurotrophic factor and glial-cell derived neurotrophic factor
    • PID: 11334998, COI: 1:CAS:528:DC%2BD3MXjtFGisb8%3D
    • Theofilopoulos S, Goggi J, Riaz SS, Jauniaux E, Stern GM, Bradford HF (2001) Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain-derived neurotrophic factor and glial-cell derived neurotrophic factor. Brain Res Dev Brain Res 127(2):111–122
    • (2001) Brain Res Dev Brain Res , vol.127 , Issue.2 , pp. 111-122
    • Theofilopoulos, S.1    Goggi, J.2    Riaz, S.S.3    Jauniaux, E.4    Stern, G.M.5    Bradford, H.F.6
  • 74
    • 0029901727 scopus 로고    scopus 로고
    • Renal agenesis and the absence of enteric neurons in mice lacking GDNF
    • PID: 8657306, COI: 1:CAS:528:DyaK28XjvFKjsr0%3D
    • Sanchez MP, Silos-Santiago I, Frisen J, He B, Lira SA, Barbacid M (1996) Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382(6586):70–73
    • (1996) Nature , vol.382 , Issue.6586 , pp. 70-73
    • Sanchez, M.P.1    Silos-Santiago, I.2    Frisen, J.3    He, B.4    Lira, S.A.5    Barbacid, M.6
  • 75
    • 1542329691 scopus 로고    scopus 로고
    • Spatially and temporally restricted chemoattractive and chemorepulsive cues direct the formation of the nigro-striatal circuit
    • PID: 15009130
    • Gates MA, Coupe VM, Torres EM, Fricker-Gates RA, Dunnett SB (2004) Spatially and temporally restricted chemoattractive and chemorepulsive cues direct the formation of the nigro-striatal circuit. Eur J Neurosci 19(4):831–844
    • (2004) Eur J Neurosci , vol.19 , Issue.4 , pp. 831-844
    • Gates, M.A.1    Coupe, V.M.2    Torres, E.M.3    Fricker-Gates, R.A.4    Dunnett, S.B.5
  • 76
    • 0034214196 scopus 로고    scopus 로고
    • Local directional cues control growth polarity of dopaminergic axons along the rostrocaudal axis
    • PID: 10818146, COI: 1:CAS:528:DC%2BD3cXjsFelurw%3D
    • Nakamura S, Ito Y, Shirasaki R, Murakami F (2000) Local directional cues control growth polarity of dopaminergic axons along the rostrocaudal axis. J Neurosci 20(11):4112–4119
    • (2000) J Neurosci , vol.20 , Issue.11 , pp. 4112-4119
    • Nakamura, S.1    Ito, Y.2    Shirasaki, R.3    Murakami, F.4
  • 77
    • 0030884756 scopus 로고    scopus 로고
    • Intrastriatal glial cell line-derived neurotrophic factor promotes sprouting of spared nigrostriatal dopaminergic afferents and induces recovery of function in a rat model of Parkinson’s disease
    • PID: 9483509, COI: 1:CAS:528:DyaK2sXmvFCrsLg%3D
    • Rosenblad C, Martinez-Serrano A, Bjorklund A (1998) Intrastriatal glial cell line-derived neurotrophic factor promotes sprouting of spared nigrostriatal dopaminergic afferents and induces recovery of function in a rat model of Parkinson’s disease. Neuroscience 82(1):129–137
    • (1998) Neuroscience , vol.82 , Issue.1 , pp. 129-137
    • Rosenblad, C.1    Martinez-Serrano, A.2    Bjorklund, A.3
  • 78
    • 0033792547 scopus 로고    scopus 로고
    • Inhibition of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum
    • PID: 11029615, COI: 1:STN:280:DC%2BD3M%2Fjtlegtg%3D%3D
    • Batchelor PE, Liberatore GT, Porritt MJ, Donnan GA, Howells DW (2000) Inhibition of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum. Eur J Neurosci 12(10):3462–3468
    • (2000) Eur J Neurosci , vol.12 , Issue.10 , pp. 3462-3468
    • Batchelor, P.E.1    Liberatore, G.T.2    Porritt, M.J.3    Donnan, G.A.4    Howells, D.W.5
  • 79
    • 0033802514 scopus 로고    scopus 로고
    • GDNF enhances the synaptic efficacy of dopaminergic neurons in culture
    • PID: 10998101, COI: 1:STN:280:DC%2BD3M%2FhslWhtA%3D%3D
    • Bourque MJ, Trudeau LE (2000) GDNF enhances the synaptic efficacy of dopaminergic neurons in culture. Eur J Neurosci 12(9):3172–3180
    • (2000) Eur J Neurosci , vol.12 , Issue.9 , pp. 3172-3180
    • Bourque, M.J.1    Trudeau, L.E.2
  • 80
    • 0030593912 scopus 로고    scopus 로고
    • Intranigral or intrastriatal injections of GDNF: effects on monoamine levels and behavior in rats
    • PID: 8997607, COI: 1:CAS:528:DyaK28XnsFSntrg%3D
    • Martin D, Miller G, Cullen T, Fischer N, Dix D, Russell D (1996) Intranigral or intrastriatal injections of GDNF: effects on monoamine levels and behavior in rats. Eur J Pharmacol 317(2–3):247–256
    • (1996) Eur J Pharmacol , vol.317 , Issue.2-3 , pp. 247-256
    • Martin, D.1    Miller, G.2    Cullen, T.3    Fischer, N.4    Dix, D.5    Russell, D.6
  • 81
    • 0036751973 scopus 로고    scopus 로고
    • Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged rhesus monkeys
    • PID: 12392792, COI: 1:CAS:528:DC%2BD38XotVChsro%3D
    • Maswood N, Grondin R, Zhang Z, Stanford JA, Surgener SP, Gash DM, Gerhardt GA (2002) Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged rhesus monkeys. Neurobiol Aging 23(5):881–889
    • (2002) Neurobiol Aging , vol.23 , Issue.5 , pp. 881-889
    • Maswood, N.1    Grondin, R.2    Zhang, Z.3    Stanford, J.A.4    Surgener, S.P.5    Gash, D.M.6    Gerhardt, G.A.7
  • 82
    • 33750607459 scopus 로고    scopus 로고
    • A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra
    • PID: 16889771, COI: 1:CAS:528:DC%2BD28Xht1ShtbfL
    • Boger HA, Middaugh LD, Huang P, Zaman V, Smith AC, Hoffer BJ, Tomac AC, Granholm AC (2006) A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra. Exp Neurol 202(2):336–347
    • (2006) Exp Neurol , vol.202 , Issue.2 , pp. 336-347
    • Boger, H.A.1    Middaugh, L.D.2    Huang, P.3    Zaman, V.4    Smith, A.C.5    Hoffer, B.J.6    Tomac, A.C.7    Granholm, A.C.8
  • 84
    • 0033038785 scopus 로고    scopus 로고
    • Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons
    • PID: 10386956, COI: 1:CAS:528:DyaK1MXktVelsbw%3D
    • Akerud P, Alberch J, Eketjall S, Wagner J, Arenas E (1999) Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. J Neurochem 73(1):70–78
    • (1999) J Neurochem , vol.73 , Issue.1 , pp. 70-78
    • Akerud, P.1    Alberch, J.2    Eketjall, S.3    Wagner, J.4    Arenas, E.5
  • 85
    • 0032102162 scopus 로고    scopus 로고
    • Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy
    • PID: 9665607, COI: 1:CAS:528:DyaK1cXktFygurc%3D
    • Tseng JL, Bruhn SL, Zurn AD, Aebischer P (1998) Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy. Neuroreport 9(8):1817–1822
    • (1998) Neuroreport , vol.9 , Issue.8 , pp. 1817-1822
    • Tseng, J.L.1    Bruhn, S.L.2    Zurn, A.D.3    Aebischer, P.4
  • 86
    • 0032751734 scopus 로고    scopus 로고
    • Differential in vivo effects of neurturin and glial cell-line-derived neurotrophic factor
    • PID: 10630208, COI: 1:CAS:528:DyaK1MXotVOktbk%3D
    • Hoane MR, Gulwadi AG, Morrison S, Hovanesian G, Lindner MD, Tao W (1999) Differential in vivo effects of neurturin and glial cell-line-derived neurotrophic factor. Exp Neurol 160(1):235–243
    • (1999) Exp Neurol , vol.160 , Issue.1 , pp. 235-243
    • Hoane, M.R.1    Gulwadi, A.G.2    Morrison, S.3    Hovanesian, G.4    Lindner, M.D.5    Tao, W.6
  • 87
    • 0037199818 scopus 로고    scopus 로고
    • Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson’s disease
    • PID: 12176170, COI: 1:CAS:528:DC%2BD38XmtlCltb8%3D
    • Oiwa Y, Yoshimura R, Nakai K, Itakura T (2002) Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson’s disease. Brain Res 947(2):271–283
    • (2002) Brain Res , vol.947 , Issue.2 , pp. 271-283
    • Oiwa, Y.1    Yoshimura, R.2    Nakai, K.3    Itakura, T.4
  • 88
    • 33845993229 scopus 로고    scopus 로고
    • Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys
    • PID: 17192932, COI: 1:CAS:528:DC%2BD2sXhsFeqtLY%3D
    • Kordower JH, Herzog CD, Dass B, Bakay RA, Stansell J 3rd, Gasmi M, Bartus RT (2006) Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys. Ann Neurol 60(6):706–715
    • (2006) Ann Neurol , vol.60 , Issue.6 , pp. 706-715
    • Kordower, J.H.1    Herzog, C.D.2    Dass, B.3    Bakay, R.A.4    Stansell, J.5    Gasmi, M.6    Bartus, R.T.7
  • 89
    • 34447572589 scopus 로고    scopus 로고
    • Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys
    • PID: 17443702
    • Herzog CD, Dass B, Holden JE, Stansell J 3rd, Gasmi M, Tuszynski MH, Bartus RT, Kordower JH (2007) Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys. Mov Disord 22(8):1124–1132
    • (2007) Mov Disord , vol.22 , Issue.8 , pp. 1124-1132
    • Herzog, C.D.1    Dass, B.2    Holden, J.E.3    Stansell, J.4    Gasmi, M.5    Tuszynski, M.H.6    Bartus, R.T.7    Kordower, J.H.8
  • 90
    • 41949110690 scopus 로고    scopus 로고
    • Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson’s disease: an open-label, phase I trial
    • PID: 18387850
    • Marks WJ Jr, Ostrem JL, Verhagen L, Starr PA, Larson PS, Bakay RA, Taylor R, Cahn-Weiner DA, Stoessl AJ, Olanow CW, Bartus RT (2008) Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson’s disease: an open-label, phase I trial. Lancet Neurol 7(5):400–408
    • (2008) Lancet Neurol , vol.7 , Issue.5 , pp. 400-408
    • Marks, W.J.1    Ostrem, J.L.2    Verhagen, L.3    Starr, P.A.4    Larson, P.S.5    Bakay, R.A.6    Taylor, R.7    Cahn-Weiner, D.A.8    Stoessl, A.J.9    Olanow, C.W.10    Bartus, R.T.11
  • 94
    • 0032408664 scopus 로고    scopus 로고
    • Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex
    • PID: 9883723, COI: 1:CAS:528:DyaK1MXntV2nsA%3D%3D
    • Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, Leitner ML, Araki T, Johnson EM Jr, Milbrandt J (1998) Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron 21(6):1291–1302
    • (1998) Neuron , vol.21 , Issue.6 , pp. 1291-1302
    • Baloh, R.H.1    Tansey, M.G.2    Lampe, P.A.3    Fahrner, T.J.4    Enomoto, H.5    Simburger, K.S.6    Leitner, M.L.7    Araki, T.8    Johnson, E.M.9    Milbrandt, J.10
  • 95
    • 0036432028 scopus 로고    scopus 로고
    • Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson’s disease
    • PID: 12401443, COI: 1:CAS:528:DC%2BD38XnvFKgsbY%3D
    • Akerud P, Holm PC, Castelo-Branco G, Sousa K, Rodriguez FJ, Arenas E (2002) Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson’s disease. Mol Cell Neurosci 21(2):205–222
    • (2002) Mol Cell Neurosci , vol.21 , Issue.2 , pp. 205-222
    • Akerud, P.1    Holm, P.C.2    Castelo-Branco, G.3    Sousa, K.4    Rodriguez, F.J.5    Arenas, E.6
  • 96
    • 33749557162 scopus 로고    scopus 로고
    • Protection by GDNF and other trophic factors against the dopamine-depleting effects of neurotoxic doses of methamphetamine
    • PID: 17105923, COI: 1:CAS:528:DC%2BD28XhtFGgs7zL
    • Cass WA, Peters LE, Harned ME, Seroogy KB (2006) Protection by GDNF and other trophic factors against the dopamine-depleting effects of neurotoxic doses of methamphetamine. Ann N Y Acad Sci 1074:272–281
    • (2006) Ann N Y Acad Sci , vol.1074 , pp. 272-281
    • Cass, W.A.1    Peters, L.E.2    Harned, M.E.3    Seroogy, K.B.4
  • 97
    • 28144450560 scopus 로고    scopus 로고
    • The GDNF family members neurturin, artemin and persephin promote the morphological differentiation of cultured ventral mesencephalic dopaminergic neurons
    • PID: 16325003, COI: 1:CAS:528:DC%2BD2MXht1OlsLvE
    • Zihlmann KB, Ducray AD, Schaller B, Huber AW, Krebs SH, Andres RH, Seiler RW, Meyer M, Widmer HR (2005) The GDNF family members neurturin, artemin and persephin promote the morphological differentiation of cultured ventral mesencephalic dopaminergic neurons. Brain Res Bull 68(1–2):42–53
    • (2005) Brain Res Bull , vol.68 , Issue.1-2 , pp. 42-53
    • Zihlmann, K.B.1    Ducray, A.D.2    Schaller, B.3    Huber, A.W.4    Krebs, S.H.5    Andres, R.H.6    Seiler, R.W.7    Meyer, M.8    Widmer, H.R.9
  • 100
    • 0037130466 scopus 로고    scopus 로고
    • Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons
    • PID: 12160745, COI: 1:CAS:528:DC%2BD38XlvVCmu70%3D
    • Honma Y, Araki T, Gianino S, Bruce A, Heuckeroth R, Johnson E, Milbrandt J (2002) Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons. Neuron 35(2):267–282
    • (2002) Neuron , vol.35 , Issue.2 , pp. 267-282
    • Honma, Y.1    Araki, T.2    Gianino, S.3    Bruce, A.4    Heuckeroth, R.5    Johnson, E.6    Milbrandt, J.7
  • 101
    • 0032403377 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor requires transforming growth factor-beta for exerting its full neurotrophic potential on peripheral and CNS neurons
    • PID: 9822741, COI: 1:CAS:528:DyaK1cXnslyqsrw%3D
    • Krieglstein K, Henheik P, Farkas L, Jaszai J, Galter D, Krohn K, Unsicker K (1998) Glial cell line-derived neurotrophic factor requires transforming growth factor-beta for exerting its full neurotrophic potential on peripheral and CNS neurons. J Neurosci 18(23):9822–9834
    • (1998) J Neurosci , vol.18 , Issue.23 , pp. 9822-9834
    • Krieglstein, K.1    Henheik, P.2    Farkas, L.3    Jaszai, J.4    Galter, D.5    Krohn, K.6    Unsicker, K.7
  • 102
    • 33846294812 scopus 로고    scopus 로고
    • GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action
    • PID: 17141511, COI: 1:CAS:528:DC%2BD2sXpvVKksw%3D%3D
    • Schober A, Peterziel H, von Bartheld CS, Simon H, Krieglstein K, Unsicker K (2007) GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action. Neurobiol Dis 25(2):378–391
    • (2007) Neurobiol Dis , vol.25 , Issue.2 , pp. 378-391
    • Schober, A.1    Peterziel, H.2    von Bartheld, C.S.3    Simon, H.4    Krieglstein, K.5    Unsicker, K.6
  • 103
    • 0037078123 scopus 로고    scopus 로고
    • TGFbeta induces GDNF responsiveness in neurons by recruitment of GFRalpha1 to the plasma membrane
    • PID: 12370242, COI: 1:CAS:528:DC%2BD38XnvFGkt7Y%3D
    • Peterziel H, Unsicker K, Krieglstein K (2002) TGFbeta induces GDNF responsiveness in neurons by recruitment of GFRalpha1 to the plasma membrane. J Cell Biol 159(1):157–167
    • (2002) J Cell Biol , vol.159 , Issue.1 , pp. 157-167
    • Peterziel, H.1    Unsicker, K.2    Krieglstein, K.3
  • 104
    • 0030051749 scopus 로고    scopus 로고
    • Expression, localization, and function of transforming growth factor-beta s in embryonic chick spinal cord, hindbrain, and dorsal root ganglia
    • PID: 8821181, COI: 1:CAS:528:DyaK28XhsFWitLY%3D
    • Unsicker K, Meier C, Krieglstein K, Sartor BM, Flanders KC (1996) Expression, localization, and function of transforming growth factor-beta s in embryonic chick spinal cord, hindbrain, and dorsal root ganglia. J Neurobiol 29(2):262–276
    • (1996) J Neurobiol , vol.29 , Issue.2 , pp. 262-276
    • Unsicker, K.1    Meier, C.2    Krieglstein, K.3    Sartor, B.M.4    Flanders, K.C.5
  • 106
    • 0028172053 scopus 로고
    • Transforming growth factor-beta promotes survival of midbrain dopaminergic neurons and protects them against N-methyl-4-phenylpyridinium ion toxicity
    • PID: 7700516, COI: 1:CAS:528:DyaK2MXisFynsLo%3D
    • Krieglstein K, Unsicker K (1994) Transforming growth factor-beta promotes survival of midbrain dopaminergic neurons and protects them against N-methyl-4-phenylpyridinium ion toxicity. Neuroscience 63(4):1189–1196
    • (1994) Neuroscience , vol.63 , Issue.4 , pp. 1189-1196
    • Krieglstein, K.1    Unsicker, K.2
  • 107
    • 0038452606 scopus 로고    scopus 로고
    • Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo
    • PID: 12832542, COI: 1:CAS:528:DC%2BD3sXltlentLs%3D
    • Farkas LM, Dunker N, Roussa E, Unsicker K, Krieglstein K (2003) Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. J Neurosci 23(12):5178–5186
    • (2003) J Neurosci , vol.23 , Issue.12 , pp. 5178-5186
    • Farkas, L.M.1    Dunker, N.2    Roussa, E.3    Unsicker, K.4    Krieglstein, K.5
  • 109
    • 33749186818 scopus 로고    scopus 로고
    • Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon
    • PID: 16741229, COI: 1:CAS:528:DC%2BD28XhtFKgs7zM
    • Roussa E, Wiehle M, Dunker N, Becker-Katins S, Oehlke O, Krieglstein K (2006) Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. Stem Cells 24(9):2120–2129
    • (2006) Stem Cells , vol.24 , Issue.9 , pp. 2120-2129
    • Roussa, E.1    Wiehle, M.2    Dunker, N.3    Becker-Katins, S.4    Oehlke, O.5    Krieglstein, K.6
  • 110
    • 62149114885 scopus 로고    scopus 로고
    • Ventral mesencephalon astrocytes are more efficient than those of other regions in inducing dopaminergic neurons through higher expression level of TGF-beta3
    • PID: 18982456, COI: 1:CAS:528:DC%2BD1MXpsl2ltg%3D%3D
    • Li K, Xue B, Wang Y, Wang X, Wang H (2009) Ventral mesencephalon astrocytes are more efficient than those of other regions in inducing dopaminergic neurons through higher expression level of TGF-beta3. J Mol Neurosci 37(3):288–300
    • (2009) J Mol Neurosci , vol.37 , Issue.3 , pp. 288-300
    • Li, K.1    Xue, B.2    Wang, Y.3    Wang, X.4    Wang, H.5
  • 111
    • 32244442041 scopus 로고    scopus 로고
    • Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion
    • PID: 16243537, COI: 1:CAS:528:DC%2BD28Xhtlalu7g%3D
    • Castelo-Branco G, Sousa KM, Bryja V, Pinto L, Wagner J, Arenas E (2006) Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Mol Cell Neurosci 31(2):251–262
    • (2006) Mol Cell Neurosci , vol.31 , Issue.2 , pp. 251-262
    • Castelo-Branco, G.1    Sousa, K.M.2    Bryja, V.3    Pinto, L.4    Wagner, J.5    Arenas, E.6
  • 112
    • 55049122063 scopus 로고    scopus 로고
    • Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction
    • PID: 18420832, COI: 1:CAS:528:DC%2BD1cXpvV2murk%3D
    • Roussa E, Oehlke O, Rahhal B, Heermann S, Heidrich S, Wiehle M, Krieglstein K (2008) Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction. Stem Cells 26(7):1683–1694
    • (2008) Stem Cells , vol.26 , Issue.7 , pp. 1683-1694
    • Roussa, E.1    Oehlke, O.2    Rahhal, B.3    Heermann, S.4    Heidrich, S.5    Wiehle, M.6    Krieglstein, K.7
  • 113
    • 0030609894 scopus 로고    scopus 로고
    • TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
    • PID: 9217007, COI: 1:CAS:528:DyaK2sXks1artbk%3D
    • Sanford LP, Ormsby I, Gittenberger-de Groot AC, Sariola H, Friedman R, Boivin GP, Cardell EL, Doetschman T (1997) TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development 124(13):2659–2670
    • (1997) Development , vol.124 , Issue.13 , pp. 2659-2670
    • Sanford, L.P.1    Ormsby, I.2    Gittenberger-de Groot, A.C.3    Sariola, H.4    Friedman, R.5    Boivin, G.P.6    Cardell, E.L.7    Doetschman, T.8
  • 114
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction
    • PID: 7493022, COI: 1:CAS:528:DyaK2MXpvVCksLk%3D
    • Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J (1995) Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 11(4):415–421
    • (1995) Nat Genet , vol.11 , Issue.4 , pp. 415-421
    • Kaartinen, V.1    Voncken, J.W.2    Shuler, C.3    Warburton, D.4    Bu, D.5    Heisterkamp, N.6    Groffen, J.7
  • 115
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
    • PID: 1436033, COI: 1:CAS:528:DyaK3sXjslSqtw%3D%3D
    • Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D et al (1992) Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359(6397):693–699
    • (1992) Nature , vol.359 , Issue.6397 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3    Pawlowski, S.4    Diebold, R.J.5    Yin, M.6    Allen, R.7    Sidman, C.8    Proetzel, G.9    Calvin, D.10
  • 116
    • 58249086387 scopus 로고    scopus 로고
    • In vivo requirement of TGF-beta/GDNF cooperativity in mouse development: focus on the neurotrophic hypothesis
    • PID: 18824086, COI: 1:CAS:528:DC%2BD1MXhtFSnt78%3D
    • Rahhal B, Heermann S, Ferdinand A, Rosenbusch J, Rickmann M, Krieglstein K (2009) In vivo requirement of TGF-beta/GDNF cooperativity in mouse development: focus on the neurotrophic hypothesis. Int J Dev Neurosci 27(1):97–102
    • (2009) Int J Dev Neurosci , vol.27 , Issue.1 , pp. 97-102
    • Rahhal, B.1    Heermann, S.2    Ferdinand, A.3    Rosenbusch, J.4    Rickmann, M.5    Krieglstein, K.6
  • 117
    • 33244470664 scopus 로고    scopus 로고
    • Transforming growth factor beta2 haploinsufficient mice develop age-related nigrostriatal dopamine deficits
    • PID: 16257223, COI: 1:CAS:528:DC%2BD28Xhslyhtr0%3D
    • Andrews ZB, Zhao H, Frugier T, Meguro R, Grattan DR, Koishi K, McLennan IS (2006) Transforming growth factor beta2 haploinsufficient mice develop age-related nigrostriatal dopamine deficits. Neurobiol Dis 21(3):568–575
    • (2006) Neurobiol Dis , vol.21 , Issue.3 , pp. 568-575
    • Andrews, Z.B.1    Zhao, H.2    Frugier, T.3    Meguro, R.4    Grattan, D.R.5    Koishi, K.6    McLennan, I.S.7
  • 119
    • 77954541850 scopus 로고    scopus 로고
    • Aged Tgfbeta2/Gdnf double-heterozygous mice show no morphological and functional alterations in the nigrostriatal system
    • PID: 20458508
    • Heermann S, Opazo F, Falkenburger B, Krieglstein K, Spittau B (2010) Aged Tgfbeta2/Gdnf double-heterozygous mice show no morphological and functional alterations in the nigrostriatal system. J Neural Transm 117(6):719–727
    • (2010) J Neural Transm , vol.117 , Issue.6 , pp. 719-727
    • Heermann, S.1    Opazo, F.2    Falkenburger, B.3    Krieglstein, K.4    Spittau, B.5
  • 121
    • 0032029606 scopus 로고    scopus 로고
    • Signal transduction by bone morphogenetic proteins
    • PID: 9720756, COI: 1:CAS:528:DyaK1cXks1Cjtbs%3D
    • Kawabata M, Imamura T, Miyazono K (1998) Signal transduction by bone morphogenetic proteins. Cytokine Growth Factor Rev 9(1):49–61
    • (1998) Cytokine Growth Factor Rev , vol.9 , Issue.1 , pp. 49-61
    • Kawabata, M.1    Imamura, T.2    Miyazono, K.3
  • 122
    • 84884589234 scopus 로고    scopus 로고
    • BMP-Smad 1/5/8 signalling in the development of the nervous system
    • Hegarty SV, O’Keeffe GW, Sullivan AM (2013) BMP-Smad 1/5/8 signalling in the development of the nervous system. Prog Neurobiol 109C:28–41
    • (2013) Prog Neurobiol , vol.109C , pp. 28-41
    • Hegarty, S.V.1    O’Keeffe, G.W.2    Sullivan, A.M.3
  • 123
    • 0028860775 scopus 로고
    • Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons
    • PID: 8600306, COI: 1:CAS:528:DyaK2MXpvVWltbw%3D
    • Krieglstein K, Suter-Crazzolara C, Hotten G, Pohl J, Unsicker K (1995) Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-beta superfamily, on midbrain dopaminergic neurons. J Neurosci Res 42(5):724–732
    • (1995) J Neurosci Res , vol.42 , Issue.5 , pp. 724-732
    • Krieglstein, K.1    Suter-Crazzolara, C.2    Hotten, G.3    Pohl, J.4    Unsicker, K.5
  • 124
    • 3042789545 scopus 로고    scopus 로고
    • Expression of growth differentiation factor-5 in the developing and adult rat brain
    • PID: 15246706
    • O’Keeffe GW, Hanke M, Pohl J, Sullivan AM (2004) Expression of growth differentiation factor-5 in the developing and adult rat brain. Brain Res Dev Brain Res 151(1–2):199–202
    • (2004) Brain Res Dev Brain Res , vol.151 , Issue.1-2 , pp. 199-202
    • O’Keeffe, G.W.1    Hanke, M.2    Pohl, J.3    Sullivan, A.M.4
  • 125
    • 0028232724 scopus 로고
    • Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily
    • PID: 8145850, COI: 1:CAS:528:DyaK2cXkvVShsrs%3D
    • Storm EE, Huynh TV, Copeland NG, Jenkins NA, Kingsley DM, Lee SJ (1994) Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily. Nature 368(6472):639–643
    • (1994) Nature , vol.368 , Issue.6472 , pp. 639-643
    • Storm, E.E.1    Huynh, T.V.2    Copeland, N.G.3    Jenkins, N.A.4    Kingsley, D.M.5    Lee, S.J.6
  • 126
    • 20044366223 scopus 로고    scopus 로고
    • Effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro
    • PID: 15906156
    • O’Keeffe GW, Dockery P, Sullivan AM (2004) Effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro. J Neurocytol 33(5):479–488
    • (2004) J Neurocytol , vol.33 , Issue.5 , pp. 479-488
    • O’Keeffe, G.W.1    Dockery, P.2    Sullivan, A.M.3
  • 127
    • 21844474854 scopus 로고    scopus 로고
    • Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain
    • PID: 15880784, COI: 1:CAS:528:DC%2BD2MXkvF2nurk%3D
    • Wood TK, McDermott KW, Sullivan AM (2005) Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain. J Neurosci Res 80(6):759–766
    • (2005) J Neurosci Res , vol.80 , Issue.6 , pp. 759-766
    • Wood, T.K.1    McDermott, K.W.2    Sullivan, A.M.3
  • 128
    • 35448998785 scopus 로고    scopus 로고
    • Differential effects of GDF5 on the medial and lateral rat ventral mesencephalon
    • PID: 17935884, COI: 1:CAS:528:DC%2BD2sXht1Kjsb3I
    • Clayton KB, Sullivan AM (2007) Differential effects of GDF5 on the medial and lateral rat ventral mesencephalon. Neurosci Lett 427(3):132–137
    • (2007) Neurosci Lett , vol.427 , Issue.3 , pp. 132-137
    • Clayton, K.B.1    Sullivan, A.M.2
  • 129
    • 77952243958 scopus 로고    scopus 로고
    • Effects of GDF5 overexpression on embryonic rat dopaminergic neurones in vitro and in vivo
    • PID: 20349094
    • O’Sullivan DB, Harrison PT, Sullivan AM (2010) Effects of GDF5 overexpression on embryonic rat dopaminergic neurones in vitro and in vivo. J Neural Transm 117(5):559–572
    • (2010) J Neural Transm , vol.117 , Issue.5 , pp. 559-572
    • O’Sullivan, D.B.1    Harrison, P.T.2    Sullivan, A.M.3
  • 130
    • 0032983894 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons are protected from radical induced damage by GDF-5 application. Short communication
    • PID: 10226934, COI: 1:CAS:528:DyaK1MXksVaksrg%3D
    • Lingor P, Unsicker K, Krieglstein K (1999) Midbrain dopaminergic neurons are protected from radical induced damage by GDF-5 application. Short communication. J Neural Transm 106(2):139–144
    • (1999) J Neural Transm , vol.106 , Issue.2 , pp. 139-144
    • Lingor, P.1    Unsicker, K.2    Krieglstein, K.3
  • 131
    • 20044366223 scopus 로고    scopus 로고
    • Effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro
    • PID: 15906156
    • O’Keeffe GW, Dockery P, Sullivan AM (2004) Effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro. J Neurocytol 33(5):479–488
    • (2004) J Neurocytol , vol.33 , Issue.5 , pp. 479-488
    • O’Keeffe, G.W.1    Dockery, P.2    Sullivan, A.M.3
  • 132
    • 84880931569 scopus 로고    scopus 로고
    • BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons
    • Hegarty SV, Sullivan AM, O’Keeffe GW (2013) BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons. Mol Cell Neurosci 56C:263–271
    • (2013) Mol Cell Neurosci , vol.56C , pp. 263-271
    • Hegarty, S.V.1    Sullivan, A.M.2    O’Keeffe, G.W.3
  • 133
    • 0029831660 scopus 로고    scopus 로고
    • Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5
    • PID: 8702914, COI: 1:CAS:528:DyaK28XlsVWqt7w%3D
    • Nishitoh H, Ichijo H, Kimura M, Matsumoto T, Makishima F, Yamaguchi A, Yamashita H, Enomoto S, Miyazono K (1996) Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5. J Biol Chem 271(35):21345–21352
    • (1996) J Biol Chem , vol.271 , Issue.35 , pp. 21345-21352
    • Nishitoh, H.1    Ichijo, H.2    Kimura, M.3    Matsumoto, T.4    Makishima, F.5    Yamaguchi, A.6    Yamashita, H.7    Enomoto, S.8    Miyazono, K.9
  • 134
    • 34047191826 scopus 로고    scopus 로고
    • Midbrain dopamine neuron differentiation: factors and fates
    • PID: 17331494, COI: 1:CAS:528:DC%2BD2sXjvFeht7g%3D
    • Abeliovich A, Hammond R (2007) Midbrain dopamine neuron differentiation: factors and fates. Dev Biol 304(2):447–454
    • (2007) Dev Biol , vol.304 , Issue.2 , pp. 447-454
    • Abeliovich, A.1    Hammond, R.2
  • 135
    • 0343683400 scopus 로고    scopus 로고
    • Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson’s disease
    • PID: 9350835, COI: 1:CAS:528:DyaK2sXmtlCiu7Y%3D
    • Sullivan AM, Opacka-Juffry J, Hotten G, Pohl J, Blunt SB (1997) Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson’s disease. Neurosci Lett 233(2–3):73–76
    • (1997) Neurosci Lett , vol.233 , Issue.2-3 , pp. 73-76
    • Sullivan, A.M.1    Opacka-Juffry, J.2    Hotten, G.3    Pohl, J.4    Blunt, S.B.5
  • 136
    • 0033528280 scopus 로고    scopus 로고
    • Neuroprotective effects of growth/differentiation factor 5 depend on the site of administration
    • PID: 9914454, COI: 1:CAS:528:DyaK1MXmtVGjsg%3D%3D
    • Sullivan AM, Opacka-Juffry J, Pohl J, Blunt SB (1999) Neuroprotective effects of growth/differentiation factor 5 depend on the site of administration. Brain Res 818(1):176–179
    • (1999) Brain Res , vol.818 , Issue.1 , pp. 176-179
    • Sullivan, A.M.1    Opacka-Juffry, J.2    Pohl, J.3    Blunt, S.B.4
  • 137
    • 0346373878 scopus 로고    scopus 로고
    • Neuroprotective effects of delayed administration of growth/differentiation factor-5 in the partial lesion model of Parkinson’s disease
    • PID: 14736509, COI: 1:CAS:528:DC%2BD2cXltVGjsQ%3D%3D
    • Hurley FM, Costello DJ, Sullivan AM (2004) Neuroprotective effects of delayed administration of growth/differentiation factor-5 in the partial lesion model of Parkinson’s disease. Exp Neurol 185(2):281–289
    • (2004) Exp Neurol , vol.185 , Issue.2 , pp. 281-289
    • Hurley, F.M.1    Costello, D.J.2    Sullivan, A.M.3
  • 138
    • 84866747289 scopus 로고    scopus 로고
    • Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson’s disease
    • PID: 22436046, COI: 1:CAS:528:DC%2BC38XhvVOis7bL
    • Costello DJ, O’Keeffe GW, Hurley FM, Sullivan AM (2012) Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson’s disease. J Cell Mol Med 16(10):2451–2460
    • (2012) J Cell Mol Med , vol.16 , Issue.10 , pp. 2451-2460
    • Costello, D.J.1    O’Keeffe, G.W.2    Hurley, F.M.3    Sullivan, A.M.4
  • 139
    • 0031840772 scopus 로고    scopus 로고
    • Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line- derived neurotrophic factor against 6hydroxydopamine in vivo
    • Sullivan AM, Opacka-Juffry J, Blunt SB (1998) Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line- derived neurotrophic factor against 6hydroxydopamine in vivo. Eur J Neurosci 10(1):57–63
    • (1998) Eur J Neurosci , vol.10 , Issue.1 , pp. 57-63
    • Sullivan, A.M.1    Opacka-Juffry, J.2    Blunt, S.B.3
  • 140
    • 85052609997 scopus 로고    scopus 로고
    • Nigrostriatal alterations in bone morphogenetic protein receptor II dominant negative mice
    • PID: 18642641, COI: 1:STN:280:DC%2BD1cvmsFKktQ%3D%3D
    • Chou J, Harvey BK, Ebendal T, Hoffer B, Wang Y (2008) Nigrostriatal alterations in bone morphogenetic protein receptor II dominant negative mice. Acta Neurochir Suppl 101:93–98
    • (2008) Acta Neurochir Suppl , vol.101 , pp. 93-98
    • Chou, J.1    Harvey, B.K.2    Ebendal, T.3    Hoffer, B.4    Wang, Y.5
  • 141
    • 84901362605 scopus 로고    scopus 로고
    • O’Keeffe GW: Canonical BMP-Smad signalling promotes neurite growth in midbrain dopaminergic neurons. NeuroMolecular Med
    • Hegarty SV, Collins LM, Gavin AM, Roche SL, Wyatt SL, Sullivan AM, O’Keeffe GW (2014) Canonical BMP-Smad signalling promotes neurite growth in midbrain dopaminergic neurons. NeuroMolecular Med (in revision)
    • (2014) Sullivan AM
    • Hegarty, S.V.1    Collins, L.M.2    Gavin, A.M.3    Roche, S.L.4    Wyatt, S.L.5
  • 142
    • 0036903815 scopus 로고    scopus 로고
    • Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan
    • PID: 12414995, COI: 1:CAS:528:DC%2BD38XpvVSqtLs%3D
    • Barnett MW, Fisher CE, Perona-Wright G, Davies JA (2002) Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan. J Cell Sci 115(Pt 23):4495–4503
    • (2002) J Cell Sci , vol.115 , pp. 4495-4503
    • Barnett, M.W.1    Fisher, C.E.2    Perona-Wright, G.3    Davies, J.A.4
  • 143
    • 24944520789 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells
    • PID: 16086701, COI: 1:CAS:528:DC%2BD2MXhtVaksbrM
    • Iwase T, Jung CG, Bae H, Zhang M, Soliven B (2005) Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells. J Neurochem 94(6):1488–1499
    • (2005) J Neurochem , vol.94 , Issue.6 , pp. 1488-1499
    • Iwase, T.1    Jung, C.G.2    Bae, H.3    Zhang, M.4    Soliven, B.5
  • 145
    • 0036935247 scopus 로고    scopus 로고
    • Bone morphogenetic proteins but not growth differentiation factors induce dopaminergic differentiation in mesencephalic precursors
    • PID: 12498780, COI: 1:CAS:528:DC%2BD38Xps12rsb0%3D
    • Brederlau A, Faigle R, Kaplan P, Odin P, Funa K (2002) Bone morphogenetic proteins but not growth differentiation factors induce dopaminergic differentiation in mesencephalic precursors. Mol Cell Neurosci 21(3):367–378
    • (2002) Mol Cell Neurosci , vol.21 , Issue.3 , pp. 367-378
    • Brederlau, A.1    Faigle, R.2    Kaplan, P.3    Odin, P.4    Funa, K.5
  • 146
    • 0030875989 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells
    • PID: 9283824, COI: 1:STN:280:DyaK2svivFCktg%3D%3D
    • Jordan J, Bottner M, Schluesener HJ, Unsicker K, Krieglstein K (1997) Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. Eur J Neurosci 9(8):1699–1709
    • (1997) Eur J Neurosci , vol.9 , Issue.8 , pp. 1699-1709
    • Jordan, J.1    Bottner, M.2    Schluesener, H.J.3    Unsicker, K.4    Krieglstein, K.5
  • 147
    • 0345517087 scopus 로고    scopus 로고
    • Localized expression of BMP and GDF mRNA in the rodent brain
    • PID: 10369215, COI: 1:CAS:528:DyaK1MXjs1ehurY%3D
    • Soderstrom S, Ebendal T (1999) Localized expression of BMP and GDF mRNA in the rodent brain. J Neurosci Res 56(5):482–492
    • (1999) J Neurosci Res , vol.56 , Issue.5 , pp. 482-492
    • Soderstrom, S.1    Ebendal, T.2
  • 148
    • 0344443258 scopus 로고    scopus 로고
    • Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals
    • PID: 14642451, COI: 1:CAS:528:DC%2BD3sXpt1els7s%3D
    • Chen HL, Lein PJ, Wang JY, Gash D, Hoffer BJ, Chiang YH (2003) Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals. Brain Res 994(1):81–90
    • (2003) Brain Res , vol.994 , Issue.1 , pp. 81-90
    • Chen, H.L.1    Lein, P.J.2    Wang, J.Y.3    Gash, D.4    Hoffer, B.J.5    Chiang, Y.H.6
  • 149
    • 0032947640 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 promotes dissociated effects on the number and differentiation of cultured ventral mesencephalic dopaminergic neurons
    • PID: 10022564, COI: 1:CAS:528:DyaK1MXhtVejtbg%3D
    • Reiriz J, Espejo M, Ventura F, Ambrosio S, Alberch J (1999) Bone morphogenetic protein-2 promotes dissociated effects on the number and differentiation of cultured ventral mesencephalic dopaminergic neurons. J Neurobiol 38(2):161–170
    • (1999) J Neurobiol , vol.38 , Issue.2 , pp. 161-170
    • Reiriz, J.1    Espejo, M.2    Ventura, F.3    Ambrosio, S.4    Alberch, J.5
  • 150
    • 0032832116 scopus 로고    scopus 로고
    • Exposure of foetal mesencephalic cells to bone morphogenetic protein-2 enhances the survival of dopaminergic neurones in rat striatal grafts
    • PID: 10554973, COI: 1:CAS:528:DyaK1MXmvVGqurk%3D
    • Espejo M, Cutillas B, Ventura F, Ambrosio S (1999) Exposure of foetal mesencephalic cells to bone morphogenetic protein-2 enhances the survival of dopaminergic neurones in rat striatal grafts. Neurosci Lett 275(1):13–16
    • (1999) Neurosci Lett , vol.275 , Issue.1 , pp. 13-16
    • Espejo, M.1    Cutillas, B.2    Ventura, F.3    Ambrosio, S.4
  • 151
    • 0041699722 scopus 로고    scopus 로고
    • Erythropoietin and bone morphogenetic protein 7 mediate ascorbate-induced dopaminergic differentiation from embryonic mesencephalic precursors
    • PID: 12876482, COI: 1:CAS:528:DC%2BD3sXlvF2rsLk%3D
    • Lee JY, Koh HC, Chang MY, Park CH, Lee YS, Lee SH (2003) Erythropoietin and bone morphogenetic protein 7 mediate ascorbate-induced dopaminergic differentiation from embryonic mesencephalic precursors. Neuroreport 14(10):1401–1404
    • (2003) Neuroreport , vol.14 , Issue.10 , pp. 1401-1404
    • Lee, J.Y.1    Koh, H.C.2    Chang, M.Y.3    Park, C.H.4    Lee, Y.S.5    Lee, S.H.6
  • 152
    • 4444279516 scopus 로고    scopus 로고
    • Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson’s disease
    • PID: 15353217, COI: 1:CAS:528:DC%2BD2cXntlSmsrY%3D
    • Harvey BK, Mark A, Chou J, Chen GJ, Hoffer BJ, Wang Y (2004) Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson’s disease. Brain Res 1022(1–2):88–95
    • (2004) Brain Res , vol.1022 , Issue.1-2 , pp. 88-95
    • Harvey, B.K.1    Mark, A.2    Chou, J.3    Chen, G.J.4    Hoffer, B.J.5    Wang, Y.6
  • 153
    • 37849022387 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 reduces toxicity induced by high doses of methamphetamine in rodents
    • PID: 18082966, COI: 1:CAS:528:DC%2BD1cXlsFehtg%3D%3D
    • Chou J, Luo Y, Kuo CC, Powers K, Shen H, Harvey BK, Hoffer BJ, Wang Y (2008) Bone morphogenetic protein-7 reduces toxicity induced by high doses of methamphetamine in rodents. Neuroscience 151(1):92–103
    • (2008) Neuroscience , vol.151 , Issue.1 , pp. 92-103
    • Chou, J.1    Luo, Y.2    Kuo, C.C.3    Powers, K.4    Shen, H.5    Harvey, B.K.6    Hoffer, B.J.7    Wang, Y.8
  • 155
    • 43049159817 scopus 로고    scopus 로고
    • Transcriptional regulation of mesencephalic dopaminergic neurons: the full circle of life and death
    • PID: 18044702
    • Alavian KN, Scholz C, Simon HH (2008) Transcriptional regulation of mesencephalic dopaminergic neurons: the full circle of life and death. Mov Disord 23(3):319–328
    • (2008) Mov Disord , vol.23 , Issue.3 , pp. 319-328
    • Alavian, K.N.1    Scholz, C.2    Simon, H.H.3
  • 156
    • 0030878045 scopus 로고    scopus 로고
    • Xmsx-1 modifies mesodermal tissue pattern along dorsoventral axis in Xenopus laevis embryo
    • PID: 9216997, COI: 1:CAS:528:DyaK2sXks1artLk%3D
    • Maeda R, Kobayashi A, Sekine R, Lin JJ, Kung H, Maeno M (1997) Xmsx-1 modifies mesodermal tissue pattern along dorsoventral axis in Xenopus laevis embryo. Development 124(13):2553–2560
    • (1997) Development , vol.124 , Issue.13 , pp. 2553-2560
    • Maeda, R.1    Kobayashi, A.2    Sekine, R.3    Lin, J.J.4    Kung, H.5    Maeno, M.6
  • 157
    • 0346505182 scopus 로고    scopus 로고
    • Regulation of Msx genes by a Bmp gradient is essential for neural crest specification
    • PID: 14627721, COI: 1:CAS:528:DC%2BD2cXitlCjtA%3D%3D
    • Tribulo C, Aybar MJ, Nguyen VH, Mullins MC, Mayor R (2003) Regulation of Msx genes by a Bmp gradient is essential for neural crest specification. Development 130(26):6441–6452
    • (2003) Development , vol.130 , Issue.26 , pp. 6441-6452
    • Tribulo, C.1    Aybar, M.J.2    Nguyen, V.H.3    Mullins, M.C.4    Mayor, R.5
  • 158
    • 3042812309 scopus 로고    scopus 로고
    • Control of roof plate formation by Lmx1a in the developing spinal cord (Lmx1a + BMPs)
    • PID: 15148302, COI: 1:CAS:528:DC%2BD2cXltlajt74%3D
    • Chizhikov VV, Millen KJ (2004) Control of roof plate formation by Lmx1a in the developing spinal cord (Lmx1a + BMPs). Development 131(11):2693–2705
    • (2004) Development , vol.131 , Issue.11 , pp. 2693-2705
    • Chizhikov, V.V.1    Millen, K.J.2
  • 159
    • 1642303128 scopus 로고    scopus 로고
    • Distinct activities of Msx1 and Msx3 in dorsal neural tube development
    • PID: 14973289, COI: 1:CAS:528:DC%2BD2cXis1enu7Y%3D
    • Liu Y, Helms AW, Johnson JE (2004) Distinct activities of Msx1 and Msx3 in dorsal neural tube development. Development 131(5):1017–1028
    • (2004) Development , vol.131 , Issue.5 , pp. 1017-1028
    • Liu, Y.1    Helms, A.W.2    Johnson, J.E.3
  • 160
    • 5444275563 scopus 로고    scopus 로고
    • Induction and specification of midbrain dopaminergic cells: focus on SHH, FGF8, and TGF-beta
    • PID: 15322912, COI: 1:CAS:528:DC%2BD2cXos1aqsbw%3D
    • Roussa E, Krieglstein K (2004) Induction and specification of midbrain dopaminergic cells: focus on SHH, FGF8, and TGF-beta. Cell Tissue Res 318(1):23–33
    • (2004) Cell Tissue Res , vol.318 , Issue.1 , pp. 23-33
    • Roussa, E.1    Krieglstein, K.2
  • 162
    • 0031901224 scopus 로고    scopus 로고
    • Neural crest induction in Xenopus: evidence for a two-signal model
    • PID: 9609823, COI: 1:CAS:528:DyaK1cXkvFansLo%3D
    • LaBonne C, Bronner-Fraser M (1998) Neural crest induction in Xenopus: evidence for a two-signal model. Development 125(13):2403–2414
    • (1998) Development , vol.125 , Issue.13 , pp. 2403-2414
    • LaBonne, C.1    Bronner-Fraser, M.2
  • 163
    • 13344285959 scopus 로고    scopus 로고
    • Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction
    • PID: 15691759, COI: 1:CAS:528:DC%2BD2MXhsFOiu78%3D
    • Monsoro-Burq AH, Wang E, Harland R (2005) Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction. Dev Cell 8(2):167–178
    • (2005) Dev Cell , vol.8 , Issue.2 , pp. 167-178
    • Monsoro-Burq, A.H.1    Wang, E.2    Harland, R.3
  • 164
    • 28644440157 scopus 로고    scopus 로고
    • Bone morphogenetic protein signalling and vertebrate nervous system development
    • PID: 16340955, COI: 1:CAS:528:DC%2BD2MXht12ntbvK
    • Liu A, Niswander LA (2005) Bone morphogenetic protein signalling and vertebrate nervous system development. Nat Rev Neurosci 6(12):945–954
    • (2005) Nat Rev Neurosci , vol.6 , Issue.12 , pp. 945-954
    • Liu, A.1    Niswander, L.A.2
  • 165
    • 53449085169 scopus 로고    scopus 로고
    • Integrating positional information at the level of Smad1/5/8
    • PID: 18590818, COI: 1:CAS:528:DC%2BD1cXht1KmtbfM
    • Eivers E, Fuentealba LC, De Robertis EM (2008) Integrating positional information at the level of Smad1/5/8. Curr Opin Genet Dev 18(4):304–310
    • (2008) Curr Opin Genet Dev , vol.18 , Issue.4 , pp. 304-310
    • Eivers, E.1    Fuentealba, L.C.2    De Robertis, E.M.3
  • 166
    • 36248995245 scopus 로고    scopus 로고
    • Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
    • PID: 18045539, COI: 1:CAS:528:DC%2BD2sXhsVCnur7L
    • Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM (2007) Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 131(5):980–993
    • (2007) Cell , vol.131 , Issue.5 , pp. 980-993
    • Fuentealba, L.C.1    Eivers, E.2    Ikeda, A.3    Hurtado, C.4    Kuroda, H.5    Pera, E.M.6    De Robertis, E.M.7
  • 167
    • 46749154758 scopus 로고    scopus 로고
    • Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors
    • PID: 18351630
    • Bonilla S, Hall AC, Pinto L, Attardo A, Gotz M, Huttner WB, Arenas E (2008) Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. Glia 56(8):809–820
    • (2008) Glia , vol.56 , Issue.8 , pp. 809-820
    • Bonilla, S.1    Hall, A.C.2    Pinto, L.3    Attardo, A.4    Gotz, M.5    Huttner, W.B.6    Arenas, E.7
  • 168
    • 70449625586 scopus 로고    scopus 로고
    • Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics
    • PID: 19330857
    • Hebsgaard JB, Nelander J, Sabelstrom H, Jonsson ME, Stott S, Parmar M (2009) Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. Glia 57(15):1648–1658
    • (2009) Glia , vol.57 , Issue.15 , pp. 1648-1658
    • Hebsgaard, J.B.1    Nelander, J.2    Sabelstrom, H.3    Jonsson, M.E.4    Stott, S.5    Parmar, M.6
  • 169
    • 0035213755 scopus 로고    scopus 로고
    • Neural patterning in the vertebrate embryo
    • PID: 11131523, COI: 1:STN:280:DC%2BD3M7ivVyquw%3D%3D
    • Altmann CR, Brivanlou AH (2001) Neural patterning in the vertebrate embryo. Int Rev Cytol 203:447–482
    • (2001) Int Rev Cytol , vol.203 , pp. 447-482
    • Altmann, C.R.1    Brivanlou, A.H.2
  • 170
    • 36849036401 scopus 로고    scopus 로고
    • Morphogens and the control of cell proliferation and patterning in the spinal cord
    • PID: 17912034, COI: 1:CAS:528:DC%2BD1cXhsFyktw%3D%3D
    • Ulloa F, Briscoe J (2007) Morphogens and the control of cell proliferation and patterning in the spinal cord. Cell Cycle 6(21):2640–2649
    • (2007) Cell Cycle , vol.6 , Issue.21 , pp. 2640-2649
    • Ulloa, F.1    Briscoe, J.2
  • 171
    • 0034303585 scopus 로고    scopus 로고
    • Neuronal specification in the spinal cord: inductive signals and transcriptional codes
    • PID: 11262869, COI: 1:CAS:528:DC%2BD3cXotlGls78%3D
    • Jessell TM (2000) Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nat Rev Genet 1(1):20–29
    • (2000) Nat Rev Genet , vol.1 , Issue.1 , pp. 20-29
    • Jessell, T.M.1
  • 172
    • 14844300927 scopus 로고    scopus 로고
    • The floor plate: multiple cells, multiple signals
    • PID: 15738958, COI: 1:CAS:528:DC%2BD2MXhslSisbw%3D
    • Placzek M, Briscoe J (2005) The floor plate: multiple cells, multiple signals. Nat Rev Neurosci 6(3):230–240
    • (2005) Nat Rev Neurosci , vol.6 , Issue.3 , pp. 230-240
    • Placzek, M.1    Briscoe, J.2
  • 173
    • 33748951151 scopus 로고    scopus 로고
    • Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development
    • PID: 16988653, COI: 1:CAS:528:DC%2BD28Xpslamurc%3D
    • Fuccillo M, Joyner AL, Fishell G (2006) Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development. Nat Rev Neurosci 7(10):772–783
    • (2006) Nat Rev Neurosci , vol.7 , Issue.10 , pp. 772-783
    • Fuccillo, M.1    Joyner, A.L.2    Fishell, G.3
  • 174
    • 0028093078 scopus 로고
    • Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS
    • PID: 7925022, COI: 1:CAS:528:DyaK2MXktFeqsw%3D%3D
    • Echelard Y, Vassileva G, McMahon AP (1994) Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development 120(8):2213–2224
    • (1994) Development , vol.120 , Issue.8 , pp. 2213-2224
    • Echelard, Y.1    Vassileva, G.2    McMahon, A.P.3
  • 176
    • 4043064327 scopus 로고    scopus 로고
    • Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1
    • PID: 15294143, COI: 1:CAS:528:DC%2BD2cXmvFOisLc%3D
    • Zervas M, Millet S, Ahn S, Joyner AL (2004) Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron 43(3):345–357
    • (2004) Neuron , vol.43 , Issue.3 , pp. 345-357
    • Zervas, M.1    Millet, S.2    Ahn, S.3    Joyner, A.L.4
  • 178
    • 4644360723 scopus 로고    scopus 로고
    • Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity
    • PID: 15385163, COI: 1:CAS:528:DC%2BD2cXnvVyru7c%3D
    • Chesnutt C, Burrus LW, Brown AM, Niswander L (2004) Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity. Dev Biol 274(2):334–347
    • (2004) Dev Biol , vol.274 , Issue.2 , pp. 334-347
    • Chesnutt, C.1    Burrus, L.W.2    Brown, A.M.3    Niswander, L.4
  • 179
    • 9444264776 scopus 로고    scopus 로고
    • Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord
    • PID: 15469980, COI: 1:CAS:528:DC%2BD2cXhtVCjs7fM
    • Wine-Lee L, Ahn KJ, Richardson RD, Mishina Y, Lyons KM, Crenshaw EB 3rd (2004) Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development 131(21):5393–5403
    • (2004) Development , vol.131 , Issue.21 , pp. 5393-5403
    • Wine-Lee, L.1    Ahn, K.J.2    Richardson, R.D.3    Mishina, Y.4    Lyons, K.M.5    Crenshaw, E.B.6
  • 180
    • 0036805782 scopus 로고    scopus 로고
    • Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system
    • PID: 12351192, COI: 1:CAS:528:DC%2BD38Xnt1Krtb4%3D
    • Failli V, Bachy I, Retaux S (2002) Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system. Mech Dev 118(1–2):225–228
    • (2002) Mech Dev , vol.118 , Issue.1-2 , pp. 225-228
    • Failli, V.1    Bachy, I.2    Retaux, S.3
  • 182
    • 79955942391 scopus 로고    scopus 로고
    • Generation of knockout mice expressing a GFP-reporter under the control of the Lmx1a locus
    • PID: 21440093, COI: 1:CAS:528:DC%2BC3MXmtFCqurc%3D
    • Griesel G, Krug C, Yurlova L, Diaconu M, Mansouri A (2011) Generation of knockout mice expressing a GFP-reporter under the control of the Lmx1a locus. Gene Expr Patterns 11(5–6):345–348
    • (2011) Gene Expr Patterns , vol.11 , Issue.5-6 , pp. 345-348
    • Griesel, G.1    Krug, C.2    Yurlova, L.3    Diaconu, M.4    Mansouri, A.5
  • 183
    • 0033363492 scopus 로고    scopus 로고
    • Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells
    • PID: 10448218, COI: 1:CAS:528:DyaK1MXjsFSis74%3D
    • Alder J, Lee KJ, Jessell TM, Hatten ME (1999) Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells. Nat Neurosci 2(6):535–540
    • (1999) Nat Neurosci , vol.2 , Issue.6 , pp. 535-540
    • Alder, J.1    Lee, K.J.2    Jessell, T.M.3    Hatten, M.E.4
  • 184
    • 33644538315 scopus 로고    scopus 로고
    • Genetic analyses demonstrate that bone morphogenetic protein signaling is required for embryonic cerebellar development
    • PID: 16481421, COI: 1:CAS:528:DC%2BD28XitVans7o%3D
    • Qin L, Wine-Lee L, Ahn KJ, Crenshaw EB 3rd (2006) Genetic analyses demonstrate that bone morphogenetic protein signaling is required for embryonic cerebellar development. J Neurosci 26(7):1896–1905
    • (2006) J Neurosci , vol.26 , Issue.7 , pp. 1896-1905
    • Qin, L.1    Wine-Lee, L.2    Ahn, K.J.3    Crenshaw, E.B.4
  • 185
    • 0032963512 scopus 로고    scopus 로고
    • Differential patterning of ventral midline cells by axial mesoderm is regulated by BMP7 and chordin
    • PID: 9847252, COI: 1:CAS:528:DyaK1MXhsFChs74%3D
    • Dale K, Sattar N, Heemskerk J, Clarke JD, Placzek M, Dodd J (1999) Differential patterning of ventral midline cells by axial mesoderm is regulated by BMP7 and chordin. Development 126(2):397–408
    • (1999) Development , vol.126 , Issue.2 , pp. 397-408
    • Dale, K.1    Sattar, N.2    Heemskerk, J.3    Clarke, J.D.4    Placzek, M.5    Dodd, J.6
  • 186
    • 0037058936 scopus 로고    scopus 로고
    • Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species
    • PID: 12461181, COI: 1:CAS:528:DC%2BD38Xps1entrs%3D
    • Yung SY, Gokhan S, Jurcsak J, Molero AE, Abrajano JJ, Mehler MF (2002) Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species. Proc Natl Acad Sci U S A 99(25):16273–16278
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.25 , pp. 16273-16278
    • Yung, S.Y.1    Gokhan, S.2    Jurcsak, J.3    Molero, A.E.4    Abrajano, J.J.5    Mehler, M.F.6
  • 187
    • 0020636924 scopus 로고
    • Development of the serotonergic system in the rat embryo: an immunocytochemical study
    • PID: 6344960, COI: 1:STN:280:DyaL3s3jt1entQ%3D%3D
    • Wallace JA, Lauder JM (1983) Development of the serotonergic system in the rat embryo: an immunocytochemical study. Brain Res Bull 10(4):459–479
    • (1983) Brain Res Bull , vol.10 , Issue.4 , pp. 459-479
    • Wallace, J.A.1    Lauder, J.M.2
  • 188
    • 0034175873 scopus 로고    scopus 로고
    • An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo
    • PID: 10801412, COI: 1:CAS:528:DC%2BD3cXislylt7g%3D
    • Wilson SI, Graziano E, Harland R, Jessell TM, Edlund T (2000) An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo. Curr Biol 10(8):421–429
    • (2000) Curr Biol , vol.10 , Issue.8 , pp. 421-429
    • Wilson, S.I.1    Graziano, E.2    Harland, R.3    Jessell, T.M.4    Edlund, T.5
  • 189
    • 0034612499 scopus 로고    scopus 로고
    • Initiation of neural induction by FGF signalling before gastrulation
    • Streit A, Berliner AJ, Papanayotou C, Sirulnik A, Stern CD (2000) Initiation of neural induction by FGF signalling before gastrulation. Nature 406(6791):74–78
    • (2000) Nature , vol.406 , Issue.6791 , pp. 74-78
    • Streit, A.1    Berliner, A.J.2    Papanayotou, C.3    Sirulnik, A.4    Stern, C.D.5
  • 190
    • 0346594337 scopus 로고    scopus 로고
    • Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction
    • PID: 14701872, COI: 1:CAS:528:DC%2BD2cXhs1ShsA%3D%3D
    • Pera EM, Ikeda A, Eivers E, De Robertis EM (2003) Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev 17(24):3023–3028
    • (2003) Genes Dev , vol.17 , Issue.24 , pp. 3023-3028
    • Pera, E.M.1    Ikeda, A.2    Eivers, E.3    De Robertis, E.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.