[Pt(O,O′-acac)(γ-acac)(DMS)] alters SH-SY5Y cell migration and invasion by the inhibition of Na+/H+ exchanger isoform 1 occurring through a PKC-ε/ERK/mTOR pathway

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Muscella, Antonella ^a   Vetrugno, Carla ^b   Calabriso, Nadia ^a   Cossa, Luca Giulio ^a   De Pascali, Sandra Angelica ^a   Fanizzi, Francesco Paolo ^a   Marsigliante, Santo ^a  

^a UNIVERSITY OF SALENTO   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CISPLATIN; GELATINASE A; GELATINASE B; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATINUM COMPLEX; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN S6; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; S6 KINASE; SMALL INTERFERING RNA; SODIUM PROTON EXCHANGE PROTEIN 1; WORTMANNIN; ZONIPORIDE; CATION TRANSPORT PROTEIN; ISOPROTEIN; MTOR PROTEIN, HUMAN; PLATINUM DERIVATIVE; PRKCE PROTEIN, HUMAN; SLC9A1 PROTEIN, HUMAN; SODIUM PROTON EXCHANGE PROTEIN; TARGET OF RAPAMYCIN KINASE; TUMOR PROTEIN;

ALKALINIZATION; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; CELL ASSAY; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; FILTERS AND MEMBRANES; HUMAN; HUMAN CELL; LETHALITY; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SH SY5Y CELL LINE; SIGNAL TRANSDUCTION; TUMOR INVASION; WESTERN BLOTTING; CELL MOTION; DRUG EFFECTS; GENETICS; METABOLISM; NEUROBLASTOMA; PATHOLOGY; TUMOR CELL LINE;

CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CELL MOVEMENT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MAP KINASE SIGNALING SYSTEM; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEUROBLASTOMA; PLATINUM COMPOUNDS; PROTEIN ISOFORMS; PROTEIN KINASE C-EPSILON; SODIUM-HYDROGEN ANTIPORTER; TOR SERINE-THREONINE KINASES;

EID: 84910644323     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112186     Document Type: Article

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