[Pt(O,O′-acac)(γ-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway

British Journal of Pharmacology

Volumn 153, Issue 1, 2008, Pages 34-49

  Muscella, A ^a   Calabriso, N ^a   Fanizzi, F P ^a   De Pascali, S A ^a   Urso, L ^a   Ciccarese, A ^a   Migoni, D ^a   Marsigliante, S ^a  

^a UNIVERSITY OF SALENTO   (Italy)

Author keywords

Pt(O,O acac)( acac)(DMS) ; Bcl 2; Bid; Breast; Caspases; Cisplatin; MCF 7; Mitochondrial apoptotic pathway

Indexed keywords

CASPASE 7; CASPASE 9; CISPLATIN; CYTOCHROME C; DIMETHYL SULFIDE; PLATINUM COMPLEX; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID;

APOPTOSIS; ARTICLE; CELL STRAIN MCF 7; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SPECTROFLUOROMETRY; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CISPLATIN; FEMALE; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; ORGANOPLATINUM COMPOUNDS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 37849021234     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707576     Document Type: Article

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