Nerve growth factor inhibits Na+/H+ exchange and HCO3- absorption through parallel phosphatidylinositol 3-kinase-mTOR and ERK pathways in thick ascending limb

Journal of Biological Chemistry

Volumn 283, Issue 39, 2008, Pages 26602-26611

  Good, David W ^a   George, Thampi ^a   Watts III, Bruns A ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION; BIOACTIVITY; CELL GROWTH; CELL MEMBRANES; CHEMICAL ACTIVATION; GROWTH (MATERIALS); GROWTH KINETICS; ION EXCHANGE; MAMMALS; PEPTIDES; PHOSPHORYLATION; PIGMENTS; SODIUM;

ACTIN CYTOSKELETON; BASOLATERAL MEMBRANES; EXTRACELLULAR SIGNALS; LY294002; MAMMALIAN TARGET OF RAPAMYCIN; MEDULLARY THICK ASCENDING LIMBS; NERVE GROWTH FACTORS; PHOSPHATIDYLINOSITOL; RAPAMYCIN; REGULATED KINASES; S6 KINASES; SIGNALING PATHWAYS; SPECIFIC INHIBITORS; TUMORIGENESIS; WORTMANNIN;

ANTIBIOTICS;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; AMILORIDE; BICARBONATE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; SODIUM PROTON EXCHANGE PROTEIN 1; WORTMANNIN; ENZYME INHIBITOR; PROTEIN KINASE; SLC9A1 PROTEIN, RAT; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 3; SODIUM-HYDROGEN EXCHANGER 3;

ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; LIMB; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; ABSORPTION; ANIMAL; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ABSORPTION; ANIMALS; BICARBONATES; CELL PROLIFERATION; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MALE; MAP KINASE SIGNALING SYSTEM; NERVE GROWTH FACTOR; PHOSPHORYLATION; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SODIUM-HYDROGEN ANTIPORTER;

EID: 55549133627     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803019200     Document Type: Article

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