Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): Effects of the novel and specific RSK inhibitor fmk on responses to α1-adrenergic stimulation

Molecular Pharmacology

Volumn 71, Issue 3, 2007, Pages 799-806

  Cuello, Friederike ^a   Snabaitis, Andrew K ^a   Cohen, Michael S ^b   Taunton, Jack ^b   Avkiran, Metin ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROMETHYL KETONE; PROTEIN SERINE THREONINE KINASE INHIBITOR; PROTON; S6 KINASE; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG;

ALPHA ADRENERGIC STIMULATION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ISOLATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; HEART STIMULATION; HEART VENTRICLE WALL; HUMAN; HUMAN CELL; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; CATION TRANSPORT PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RIBOSOMAL PROTEIN S6 KINASES; SODIUM-HYDROGEN ANTIPORTER;

EID: 33847122150     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.029900     Document Type: Article

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