Sublethal concentrations of the platinum(II) complex [Pt(O,O′-acac) (γ-acac)(DMS)] alter the motility and induce anoikis in MCF-7 cells

British Journal of Pharmacology

Volumn 160, Issue 6, 2010, Pages 1362-1377

  Muscella, Antonella ^a   Calabriso, Nadia ^a   Vetrugno, Carla ^a   Urso, Loredana ^a   Fanizzi, Francesco Paolo ^a   De Pascali, Sandra Angelica ^a   Marsigliante, Santo ^a  

^a UNIVERSITY OF SALENTO   (Italy)

Author keywords

anoikis; MCF 7; motility; p38MAPK; PKC ; ROS; Pt(O,O acac)( acac)(DMS)

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATINUM COMPLEX; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; ROTTLERIN; ANTINEOPLASTIC AGENT; PT(O,O'-ACAC)(GAMMA-ACAC)(DMS);

ANCHORAGE INDEPENDENT GROWTH; ANOIKIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL STRAIN MCF 7; COLONY FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; METASTASIS INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; BREAST NEOPLASMS; CELL MOTION; DRUG EFFECTS; FEMALE; METABOLISM; NEOPLASM METASTASIS; PATHOLOGY; TUMOR CELL LINE;

ANOIKIS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM METASTASIS; ORGANOPLATINUM COMPOUNDS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 77954041608     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00782.x     Document Type: Article

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