Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways

Nature Immunology

Volumn 14, Issue 6, 2013, Pages 611-618

  Kim, Jiyeon S ^a,b   Sklarz, Tammarah ^a   Banks, Lauren B ^a,b   Gohil, Mercy ^a   Waickman, Adam T ^c   Skuli, Nicolas ^a   Krock, Bryan L ^a   Luo, Chong T ^d   Hu, Weihong ^e   Pollizzi, Kristin N ^c   Li, Ming O ^d   Rathmell, Jeffrey C ^e   Birnbaum, Morris J ^b   Powell, Jonathan D ^c   Jordan, Martha S ^f   Koretzky, Gary A ^a,f  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 17; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B; PROTEIN KINASE B BETA; S6 KINASE; TRANSCRIPTION FACTOR FOXO; AKT1 PROTEIN, MOUSE; AKT2 PROTEIN, MOUSE; ARNT PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1BETA; MTOR PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 1; TOR COMPLEX 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL SUBPOPULATION; CONTROLLED STUDY; FLOW CYTOMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TH17 CELL; ANIMAL; C57BL MOUSE; GENETICS; HUMAN; IMMUNOBLOTTING; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; INTERLEUKIN-17; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MULTIPROTEIN COMPLEXES; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TH17 CELLS; TOR SERINE-THREONINE KINASES;

MLCS; MLOWN;

EID: 84878238075     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2607     Document Type: Article

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