Functional expression of choline transporter-like protein 1 (CTL1) in human neuroblastoma cells and its link to acetylcholine synthesis

Neurochemistry International

Volumn 58, Issue 3, 2011, Pages 354-365

  Yamada, Tomoko ^a   Inazu, Masato ^a   Tajima, Hirohisa ^a   Matsumiya, Teruhiko ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Acetylcholine; Choline; Choline transporter like protein; High affinity choline transporter; Na + H + exchanger; Neuroblastoma; Transporter

Indexed keywords

ACETYLCHOLINE; CATION; CHOLINE TRANSPORTER LIKE PROTEIN 1; CHOLINERGIC RECEPTOR; HEMICHOLINIUM 3; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 1; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL MEMBRANE; CHOLINE UPTAKE; CHOLINERGIC NERVE CELL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MALE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SODIUM TRANSPORT; SYNTHESIS; WESTERN BLOTTING;

ACETYLCHOLINE; ANIMALS; ANTIGENS, CD; BRAIN NEOPLASMS; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; NEUROBLASTOMA; NEURONS; ORGAN CULTURE TECHNIQUES; ORGANIC CATION TRANSPORT PROTEINS; RATS; RATS, WISTAR;

EID: 79951579758     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2010.12.011     Document Type: Article

References (41)

1. S. Apparsundaram, S.M. Ferguson, George A.L.Jr., and R.D. Blakely Molecular cloning of a human, hemicholinium-3-sensitive choline transporter Biochem. Biophys. Res. Commun. 276 2000 862 867
2. S. Apparsundaram, S.M. Ferguson, and R.D. Blakely Molecular cloning and characterization of a murine hemicholinium-3-sensitive choline transporter Biochem. Soc. Trans. 29 2001 711 716 (Pubitemid 33131767)
3. + exchanger (NHE5) highly expressed in brain J. Biol. Chem. 274 1999 4383 4388
4. + exchanger isoform 5 by protein kinases A and C and cell shrinkage Am. J. Physiol. Cell Physiol. 281 2001 C1146 C1157
5. + exchanger isoform 5 (NHE5) from human brain J. Biol. Chem. 274 1999 4377 4382
6. J.L. Biedler, S. Roffler-Tarlov, M. Schachner, and L.S. Freedman Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones Cancer Res. 38 1978 3751 3757 (Pubitemid 9045201)
7. J.K. Blusztajn, and R.J. Wurtman Choline and cholinergic neurons Science 221 1983 614 620 (Pubitemid 13026078)
8. Y.H. Che, T. Yamashita, H. Higuchi, and M. Tohyama Changes in mRNA for choline transporter-like protein following facial nerve transection Brain Res. Mol. Brain Res. 101 2002 122 125 (Pubitemid 34465568)
9. Y. Cheng, and W.H. Prusoff Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (IC50) of an enzymatic reaction Biochem. Pharmacol. 22 1973 3099 3108
10. V. Dolezal, S. Tucek, and S. Hynie Effects of pertussis toxin suggest a role for G-proteins in the inhibition of acetylcholine release from rat myenteric plexus by opioid and presynaptic muscarinic receptors Eur. J. Neurosci. 1 1989 127 131 (Pubitemid 19148390)
11. S.M. Ferguson, M. Bazalakova, V. Savchenko, J.C. Tapia, J. Wright, and R.D. Blakely Lethal impairment of cholinergic neurotransmission in hemicholinium-3-sensitive choline transporter knockout mice Proc. Natl. Acad. Sci. U. S. A. 101 2004 8762 8767 (Pubitemid 38745845)
12. A. Friedrich, R.L. George, C.C. Bridges, P.D. Prasad, and V. Ganapathy Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4) Biochim. Biophys. Acta 1512 2001 299 307 (Pubitemid 32530777)
13. +-independent choline transport in primary cultures of neurons from mouse cerebral cortex Neurosci. Lett. 393 2005 216 221
14. M.D. Fullerton, L. Wagner, Z. Yuan, and M. Bakovic Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages Am. J. Physiol. Cell Physiol. 290 2006 C1230 C1238
15. +-independent choline transporter in rat astrocytes J. Neurochem. 94 2005 1427 1437 (Pubitemid 41232598)
16. J.W. Jonker, and A.H. Schinkel Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3) J. Pharmacol. Exp. Ther. 308 2004 2 9 (Pubitemid 38090693)
17. R. Kekuda, P.D. Prasad, X. Wu, H. Wang, Y.J. Fei, F.H. Leibach, and V. Ganapathy Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta J. Biol. Chem. 273 1998 15971 15979 (Pubitemid 28311362)
18. + exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2 Am. J. Physiol. Cell Physiol. 289 2005 C934 C945
19. J. Klein, A. Köppen, K. Löffelholz, and J. Schmitthenner Uptake and metabolism of choline by rat brain after acute choline administration J. Neurochem. 58 1992 870 876
20. J. Klein, R. Gonzalez, A. Köppen, and K. Löffelholz Free choline and choline metabolites in rat brain and body fluids: sensitive determination and implications for choline supply to the brain Neurochem. Int. 22 1993 293 300
21. H. Kouji, M. Inazu, T. Yamada, H. Tajima, T. Aoki, and T. Matsumiya Molecular and functional characterization of choline transporter in human colon carcinoma HT-29 cells Arch. Biochem. Biophys. 483 2009 90 98
22. E. Machova, S. O'Regan, J. Newcombe, F.M. Meunier, J. Prentice, R. Dove, and V. Dolezal Detection of choline transporter-like 1 protein CTL1 in neuroblastoma × glioma cells and in the CNS, and its role in choline uptake J. Neurochem. 110 2009 1297 1309
23. V. Michel, Z. Yuan, S. Ramsubir, and M. Bakovic Choline transport for phospholipid synthesis Exp. Biol. Med. (Maywood) 231 2006 490 504
24. H. Misawa, K. Nakata, J. Matsuura, M. Nagao, T. Okuda, and T. Haga Distribution of the high-affinity choline transporter in the central nervous system of the rat Neuroscience 105 2001 87 98 (Pubitemid 32722096)
25. T.S. Nair, K.E. Kozma, N.L. Hoefling, P.K. Kommareddi, Y. Ueda, T.W. Gong, M.I. Lomax, C.D. Lansford, S.A. Telian, B. Satar, H.A. Arts, H.K. El-Kashlan, W.E. Berryhill, Y. Raphael, and T.E. Carey Identification and characterization of choline transporter-like protein 2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss J. Neurosci. 24 2004 1772 1779 (Pubitemid 38240975)
26. T. Nakamura, R. Fujiwara, N. Ishiguro, M. Oyabu, T. Nakanishi, Y. Shirasaka, T. Maeda, and I. Tamai Involvement of choline transporter-like proteins, CTL1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine synthesis via increased choline uptake Biol. Pharm. Bull. 33 2010 691 696
27. T. Okuda, T. Haga, Y. Kanai, H. Endou, T. Ishihara, and I. Katsura Identification and characterization of the high-affinity choline transporter Nat. Neurosci. 3 2000 120 125 (Pubitemid 30126326)
28. S. O'Regan, E. Traiffort, M. Ruat, N. Cha, D. Compaore, and F.M. Meunier An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins Proc. Natl. Acad. Sci. U. S. A. 97 2000 1835 1840 (Pubitemid 30118529)
29. J. Orlowski Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger J. Biol. Chem. 268 1993 16369 16377 (Pubitemid 23229940)
30. J. Orlowski, and S. Grinstein Diversity of the mammalian sodium/proton exchanger SLC9 gene family Pflugers Arch. Eur. J. Physiol. 447 2004 549 565 (Pubitemid 38241440)
31. M.A. Prado, R.A. Reis, V.F. Prado, M.C. de Mello, M.V. Gomez, and F.G. de Mello Regulation of acetylcholine synthesis and storage Neurochem. Int. 41 2002 291 299
32. F.M. Ribeiro, M. Pinthong, S.A. Black, A.C. Gordon, V.F. Prado, M.A. Prado, R.J. Rylett, and S.S. Ferguson Regulated recycling and plasma membrane recruitment of the high-affinity choline transporter Eur. J. Neurosci. 26 2007 3437 3448 (Pubitemid 350243538)
33. U.I. Richardson, M. Liscovitch, and J.K. Blusztajn Acetylcholine synthesis and secretion by LA-N-2 human neuroblastoma cells Brain Res. 476 1989 323 331 (Pubitemid 19012601)
34. A. Roos, and W.F. Boron Intracellular pH Physiol. Rev. 61 1981 296 434
35. R.A. Ross, B.A. Spengler, and J.L. Biedler Coordinate morphological and biochemical interconversion of human neuroblastoma cells J. Natl. Cancer Inst. 71 1983 741 747 (Pubitemid 14232388)
36. 3H]pirenzepine binding associated with hydrolysis of phosphatidylinositols J. Neurochem. 50 1988 1513 1521
37. E. Traiffort, M. Ruat, S. O'Regan, and F.M. Meunier Molecular characterization of the family of choline transporter-like proteins and their splice variants J. Neurochem. 92 2005 1116 1125 (Pubitemid 40344302)
38. Y. Uchida, M. Inazu, H. Takeda, T. Yamada, H. Tajima, and T. Matsumiya Expression and functional characterization of choline transporter in human keratinocytes J. Pharmacol. Sci. 109 2009 102 109
39. Y. Urakami, M. Okuda, S. Masuda, H. Saito, and K.I. Inui Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs J. Pharmacol. Exp. Ther. 287 1998 800 805 (Pubitemid 29133685)
40. + ionophore Cancer Res. 37 1977 1372 1376 (Pubitemid 8104874)
41. M. Yabuki, M. Inazu, T. Yamada, H. Tajima, and T. Matsumiya Molecular and functional characterization of choline transporter in rat renal tubule epithelial NRK-52E cells Arch. Biochem. Biophys. 485 2009 88 96