Oxidative damage to osteoblasts can be alleviated by early autophagy through the endoplasmic reticulum stress pathway - Implications for the treatment of osteoporosis

Free Radical Biology and Medicine

Volumn 77, Issue , 2014, Pages 10-20

  Yang, Yue Hua ^a   Li, Bo ^a   Zheng, Xin Feng ^a   Chen, Jiang Wei ^a   Chen, Ke ^a   Jiang, Sheng Dan ^a   Jiang, Lei Sheng ^a  

^a XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; Autophagy; Endoplasmic reticulum stress; Osteoblast; Oxidative stress

Indexed keywords

3 METHYLADENINE; 8 HYDROXYDEOXYGUANOSINE; BAFILOMYCIN A1; BECLIN 1; CELL MARKER; CELL PROTEIN; GLUCOSE REGULATED PROTEIN 78; HYDROGEN PEROXIDE; MALONALDEHYDE; PROTEIN KINASE; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGY; CELL DAMAGE; CELL LEVEL; CELL PROTECTION; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; DOSE RESPONSE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE OVEREXPRESSION; GENETIC TRANSFECTION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MURINAE; NONHUMAN; OSTEOBLAST; OSTEOPOROSIS; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RNA INTERFERENCE; ANIMAL; CELL LINE; CELL SURVIVAL; HUMAN; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; OSTEOBLASTS; OSTEOPOROSIS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84908413236     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.08.028     Document Type: Article

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