Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells

Cell Death and Disease

Volumn 4, Issue 4, 2013, Pages

  Yang, Y C ^a,b,c   Fu, H C ^a,b,c   Hsiao, B L ^b,d   Sobue, G ^e   Adachi, H ^e   Huang, F J ^c   Hsuuw, Y D ^f   Wei, K T ^b   Chang, C ^g   Huang, K E ^b,c   Kang, H Y ^a,b,d  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^e NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^g UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Androgen receptor; Embryonic stem cells; GRP78 BiP; Polyglutamine; Spinal bulbar muscular atrophy

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ANDROGEN; ANDROGEN RECEPTOR; CASPASE 3; CHAPERONE; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CULTURAL ANTHROPOLOGY; CYTOPATHOLOGY; EMBRYOID BODY; EMBRYONIC STEM CELL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE OVEREXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; MOUSE; MUSCLE ATROPHY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN ISOLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA ISOLATION; STRESS; UBIQUITINATION; UPREGULATION; VIRUS INFECTION;

ACTIVATING TRANSCRIPTION FACTOR 6; ANDROGENS; ANIMALS; APOPTOSIS; CASPASE 3; CELL DIFFERENTIATION; CELL LINE; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS; MICE; MICE, TRANSGENIC; RECEPTORS, ANDROGEN; RNA INTERFERENCE; RNA, SMALL INTERFERING; UBIQUITINATION;

MUS MUSCULUS;

EID: 84876912984     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.122     Document Type: Article

References (36)

1. Smith MA, Seibel NL, Altekruse SF, Ries LA, Melbert DL, O'Leary M et al. Outcomes for children and adolescents with cancer: Challenges for the twenty-first century. J Clin Oncol 2010; 28: 2625-2634
2. Dreifaldt AC, Carlberg M, Hardell L. Increasing incidence rates of childhood malignant diseases in Sweden during the period 1960-1998. Eur J Cancer 2004; 40: 1351-1360
3. Rosychuk RJ, Witol A, Wilson B, Stobart K. Central nervous system (CNS) tumor trends in children in a western Canadian province: A population-based 22-year retrospective study. J Neurol 2012; 259: 1131-1136
4. Gatta G, Capocaccia R, Stiller C, Kaatsch P, Berrino F, Terenziani M. Childhood cancer survival trends in Europe: A EUROCARE Working Group study. J Clin Oncol 2005; 23: 3742-3751
5. Magnani C, Pastore G, Coebergh JW, Viscomi S, Spix C, Steliarova-Foucher E. Trends in survival after childhood cancer in Europe, 1978-1997: Report from the Automated Childhood Cancer Information System project (ACCIS). Eur J Cancer 2006; 42: 1981-2005
6. Lannering B, Marky I, Lundberg A, Olsson E. Long-Term sequelae after pediatric brain tumors: Their effect on disability and quality of life. Med Pediatr Oncol 1990; 18: 304-310
7. Lannering B, Marky I, Nordborg C. Brain tumors in childhood and adolescence in west Sweden 1970-1984. Epidemiology and survival. Cancer 1990; 66: 604-609
8. Hall P, Adami HO, Trichopoulos D, Pedersen NL, Lagiou P, Ekbom A et al. Effect of low doses of ionising radiation in infancy on cognitive function in adulthood: Swedish population based cohort study. BMJ 2004; 328: 19
9. Fukuda H, Fukuda A, Zhu C, Korhonen L, Swanpalmer J, Hertzman S et al. Irradiationinduced progenitor cell death in the developing brain is resistant to erythropoietin treatment and caspase inhibition. Cell Death Differ 2004; 11: 1166-1178
10. Monje ML, Mizumatsu S, Fike JR, Palmer TD. Irradiation induces neural precursor-cell dysfunction. Nat Med 2002; 8: 955-962
11. Raber J, Rola R, LeFevour A, Morhardt D, Curley J, Mizumatsu S et al. Radiation-Induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis. Radiat Res 2004; 162: 39-47
12. Rola R, Raber J, Rizk A, Otsuka S, VandenBerg SR, Morhardt DR et al. Radiation-Induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice. Exp Neurol 2004; 188: 316-330
13. Naylor AS, Bull C, Nilsson MK, Zhu C, Bjork-Eriksson T, Eriksson PS et al. Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain. Proc Natl Acad Sci USA 2008; 105: 14632-14637
14. Karlsson N, Kalm M, Nilsson MK, Mallard C, Bjork-Eriksson T, Blomgren K. Learning and activity after irradiation of the young mouse brain analyzed in adulthood using unbiased monitoring in a home cage environment. Radiat Res 2011; 175: 336-346
15. Roughton K, Kalm M, Blomgren K. Sex-dependent differences in behavior and hippocampal neurogenesis after irradiation to the young mouse brain. Eur J Neurosci 2012; 36: 2763-2772
16. Fukuda A, Fukuda H, Swanpalmer J, Hertzman S, Lannering B, Marky I et al. Age-dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells. J Neurochem 2005; 92: 569-584
17. Hellstrom NA, Bjork-Eriksson T, Blomgren K, Kuhn HG. Differential recovery of neural stem cells in the subventricular zone and dentate gyrus after ionizing radiation. Stem Cells 2009; 27: 634-641
18. van't Hooft I, Norberg AL. SMART cognitive training combined with a parental coaching programme for three children treated for medulloblastoma. NeuroRehabilitation 2010; 26: 105-113
19. Acharya MM, Christie LA, Lan ML, Donovan PJ, Cotman CW, Fike Jr. et al. Rescue of radiation-Induced cognitive impairment through cranial transplantation of human embryonic stem cells. Proc Natl Acad Sci USA 2009; 106: 19150-19155
20. Kalm M, Fukuda A, Fukuda H, Ohrfelt A, Lannering B, Bjork-Eriksson T et al. Transient inflammation in neurogenic regions after irradiation of the developing brain. Radiat Res 2009; 171: 66-76
21. Kalm M, Lannering B, Bjork-Eriksson T, Blomgren K. Irradiation-Induced loss of microglia in the young brain. J Neuroimmunol 2009; 206: 70-75
22. Monje ML, Toda H, Palmer TD. Inflammatory blockade restores adult hippocampal neurogenesis. Science 2003; 302: 1760-1765
23. Belmadani A, Tran PB, Ren D, Miller RJ. Chemokines regulate the migration of neural progenitors to sites of neuroinflammation. J Neurosci 2006; 26: 3182-3191
24. Yang HY, Mitchell K, Keller JM, Iadarola MJ. Peripheral inflammation increases Scya2 expression in sensory ganglia and cytokine and endothelial related gene expression in inflamed tissue. J Neurochem 2007; 103: 1628-1643
25. Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci USA 2004; 101: 18117-18122
26. Nakamura M, Houghtling RA, MacArthur L, Bayer BM, Bregman BS. Differences in cytokine gene expression profile between acute and secondary injury in adult rat spinal cord. Exp Neurol 2003; 184: 313-325
27. Okada S, Ishii K, Yamane J, Iwanami A, Ikegami T, Katoh H et al. In vivo imaging of engrafted neural stem cells: Its application in evaluating the optimal timing of transplantation for spinal cord injury. FASEB J 2005; 19: 1839-1841
28. Rosenblum S, Wang N, Smith TN, Pendharkar AV, Chua JY, Birk H et al. Timing of intraarterial neural stem cell transplantation after hypoxia-Ischemia influences cell engraftment, survival, and differentiation. Stroke 2012; 43: 1624-1631
29. Gage FH, Coates PW, Palmer TD, Kuhn HG, Fisher LJ, Suhonen JO et al. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci USA 1995; 92: 11879-11883
30. Vietje BP, Wells J. Selective lesions of granule cells by fluid injections into the dentate gyrus. Exp Neurol 1989; 106: 275-282
31. Cassel JC, Ballough GP, Kelche C, Hofferer E, Cassel S, Will B. Injections of fluid or septal cell suspension grafts into the dentate gyrus of rats induce granule cell degeneration. Neurosci Lett 1993; 150: 89-94
32. Hofferer E, Cassel JC, Kelche C, Millemann P, Will B. Morphological and behavioural effects of granule cell degeneration induced by intrahippocampal fluid injections in intact and fimbria-fornix lesioned rats. Behav Brain Res 1994; 63: 167-176
33. Peissner W, Kocher M, Treuer H, Gillardon F. Ionizing radiation-Induced apoptosis of proliferating stem cells in the dentate gyrus of the adult rat hippocampus. Brain Res Mol Brain Res 1999; 71: 61-68
34. Fukuda A, Fukuda H, Jonsson M, Swanpalmer J, Hertzman S, Lannering Bet al. Progenitor cell injury after irradiation to the developing brain can be modulated by mild hypothermia or hyperthermia. J Neurochem 2005; 94: 1604-1619
35. Ray J, Gage FH. Differential properties of adult rat and mouse brain-derived neural stem/ progenitor cells. Mol Cell Neurosci 2006; 31: 560-573
36. Fowler JF. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 1989; 62: 679-694