Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids

Journal of Biological Chemistry

Volumn 282, Issue 37, 2007, Pages 27285-27297

  Almeida, Maria ^a   Han, Li ^a   Martin Millan, Marta ^a   Plotkin, Lilian I ^a   Stewart, Scott A ^a   Roberson, Paula K ^b   Kousteni, Stavroula ^a,c   O'Brien, Charles A ^a   Bellido, Teresita ^a   Parfitt, A Michael ^a   Weinstein, Robert S ^a   Jilka, Robert L ^a   Manolagas, Stavros C ^a,d  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CELL DEATH; OSTEOBLASTS; OXIDATIVE STRESS; PATHOGENS; PHOSPHORYLATION;

BONE MINERAL DENSITY; PIVOTAL PATHOGENETIC MECHANISM; SEX STEROIDS; SKELETAL INVOLUTION;

HORMONES;

ANDROGEN; CATALASE; CORTICOSTERONE; ESTROGEN; GLUCOCORTICOID; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN P53; PROTEIN P66; REACTIVE OXYGEN METABOLITE; SEX HORMONE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR FOXO;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BONE DENSITY; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; ENZYME ACTIVITY; FEMALE; FEMUR; GONADECTOMY; HOMEOSTASIS; MALE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCYTE; OSTEOLYSIS; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPINE; WESTERN BLOTTING;

AGING; ANDROGENS; ANIMALS; ANTIOXIDANTS; BONE AND BONES; BONE DENSITY; BONE REMODELING; ESTROGENS; FEMALE; GONADAL STEROID HORMONES; MALE; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; OVARIECTOMY; OXIDATIVE STRESS; PHOSPHORYLATION;

MUS;

EID: 34848878406     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702810200     Document Type: Article

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