Endoplasmic Reticulum Stress Signaling Is Involved in Mitomycin C(MMC)-Induced Apoptosis in Human Fibroblasts via PERK Pathway

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Shi, Kun ^a   Wang, Daode ^a   Cao, Xiaojian ^a   Ge, Yingbin ^b  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; BIM PROTEIN; CASPASE 3; CELL ENZYME; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; MITOMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE R LIKE ENDOPLASMIC RETICULUM KINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; C EBP HOMOLOGOUS PROTEIN GENE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GENE SILENCING; GLUCOSE REGULATED PROTEIN 78 GENE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIPID PEROXIDATION; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FIBROBLASTS; HEAT-SHOCK PROTEINS; HUMANS; IN SITU NICK-END LABELING; LIPID PEROXIDATION; MEMBRANE PROTEINS; MITOMYCIN; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 84875294392     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059330     Document Type: Article

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