Role of antioxidant systems, lipid peroxidation, and nitric oxide in postmenopausal osteoporosis

Molecular and Cellular Biochemistry

Volumn 295, Issue 1-2, 2007, Pages 45-52

  Ozgocmen, Salih ^a   Kaya, Huseyin ^a   Fadillioglu, Ersin ^b   Aydogan, Rabia ^a   Yilmaz, Zumrut ^c  

^a FIRAT UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

^c INONU UNIVERSITY   (Turkey)

Author keywords

Antioxidant enzyme; Malon dialdehyde; Nitric oxide; Post menopausal osteoporosis

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; CATALASE; FREE RADICAL; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; NITRATE; NITRIC OXIDE; NITRITE; SUPEROXIDE DISMUTASE;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; BONE DENSITY; BONE MASS; CONTROLLED STUDY; CORRELATION ANALYSIS; DAILY LIFE ACTIVITY; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME ACTIVITY; ERYTHROCYTE; ERYTHROCYTE LEVEL; FEMALE; FEMUR; HUMAN; INDEPENDENCE; LIPID PEROXIDATION; LUMBAR SPINE; MAJOR CLINICAL STUDY; MENTAL FUNCTION; METABOLIC PARAMETERS; OSTEOLYSIS; OXIDATIVE STRESS; PAIN; POSTMENOPAUSE OSTEOPOROSIS; QUALITY OF LIFE; SOCIAL STATUS;

ADULT; AGED; ANTIOXIDANTS; BONE DENSITY; CASE-CONTROL STUDIES; DEMOGRAPHY; ERYTHROCYTES; FEMALE; HUMANS; LIPID PEROXIDATION; MIDDLE AGED; NITRIC OXIDE; ORGAN SIZE; OSTEOPOROSIS, POSTMENOPAUSAL; OXIDATIVE STRESS;

EID: 33846546145     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9270-z     Document Type: Article

References (39)

1. Raisz LG (2005) Pathogenesis of osteoporosis: Concepts, conflicts and prospects J Clin Invest 115:3318-3325
2. Garrett IR, Boyce BF, Oreffo ROC, Bonewald L, Poser J, Mundy GR (1990) Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo J Clin Invest 85:632-639
3. Bax BE, Alam ASMT, Banerji B, Bax CMR, Bevis PJR, Stevens CR, Moonga BS, Blake DR, Zaidi M (1992) Stimulation of osteoclastic bone resorption by hydrogen peroxide Biochem Biophys Res Commun 183:1153-1158
4. Lean JM, Davies JT, Fuller K, Jagger CJ, Kirstein B, Partington GA, Urry ZL, Chambers TJ (2003) A crucial role for thiol antioxidants in estrogen-deficiency bone loss J Clin Invest 112:915-923
5. Lean JM, Jagger CJ, Kirstein B, Fuller K, Chambers TJ (2005) Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclasts formation Endocrinology 146:728-735
6. Bai XC, Lu D, Bai J, Zheng H, Ke ZY, Li XM, Luo SQ (2004) Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-β Biochem Biophys Res Commun 314:197-207
7. Park GB, Yoo CI, Kim HT, Kwon CH, Kim YK (2005) Role of mitogen-activated protein kinases in hydrogen peroxide-induced cell death in osteoblastic cells Toxicology 215:115-125
8. Varanasi SS, Francis RM, Berger CEM, Papiha SS, Datta HK (1999) Mitochondrial DNA deletion associated oxidative stress and severe male osteoporosis Osteop Int 10:143-149
9. Melhus H, Michaelsson K, Holmberg L, Wolk A, Ljunghall S (1999) Smoking, antioxidant vitamins and risk of hip fracture J Bone Miner Res 14:129-135
10. Basu S, Michaelsson K, Olofsson H, Johansson S, Melhus H (2001) Association between oxidative stress and bone mineral density Biochem Biophys Res Commun 288:275-279
11. Sontakke AN, Tare RS (2002) A duality in the roles of reactive oxygen species with respect to bone metabolism Clin Chim Acta 318:145-148
12. Maggio D, Barabani B, Pierandrei M, Polidori MC, Catani M, Mecocci P, Senin U, Pacifici R, Cherubini A (2003) Marked decrease in plasma antioxidants in aged osteoporotic women. Results of a cross-sectional study JCEM 88:1523-1527
13. Yalin S, Bagis S, Polat G, Dogruer N, Aksit SC, Hatungil R, Erdogan C (2005) Is there a role of free oxygen radicals in primary male osteoporosis Clin Exp Rheumatol 23:689-692
14. Kigwell BA (2000) Nitric oxide-mediated metabolic regulation during exercise: Effect of training in health and cardiovascular disease FASEB J 14:1685-1696
15. Akyol O, Zoroglu SS, Armutcu F, Sahin S, Gurel A (2004) Nitric oxide as a physiopathological factor in neuropsychiatric disorders In vivo 18:377-390
16. van't Hof RJ, Ralston SH (2001) Nitric oxide and bone Immunology 103:255-261
17. Aguirre J, Buttery L, O'Shaughnessy M, Afzal F, Fernandez DMI, Hukkanen M, Huang P, MacIntyre I, Polak J (2001) Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity Am J Pathol 158:247-257
18. van't Hof RJ, Armour KJ, Smith LM, Armour KE, Wei XQ, Liew FY, Ralston SH (2000) Requirement of the inducible nitric oxide synthase pathway for IL-1-induced osteoclastic bone resorption Proc Nat Acad Sci USA 97:7993-7998
19. Caballero-Alias AM, Loveridge N, Lyon A, Das-Gupta V, Pitsillides A, Reeve J (2004) NOS isoforms in adult human osteocytes: Multiple pathways of NO regulation? Calcif Tissue Int 75:78-84
20. Leidig-Bruckner G, Genant HK, Minne HW, Storm T, Thamsborg G, Bruckner T, Sauer P, Schilling T, Soerensen OH, Ziegler R (1994) Comparison of a semiquantitative and a quantitative method for assessing vertebral fractures in osteoporosis Osteoporos Int 4:154-161
21. Cerrahoglu L, Duruoz MT, Tikiz C, Olcenler S, Tulukoglu N, Susin A (2002) Postmenopozal kadinlarda diyetle kalsiyum alimi ile kemik mineral yogunlugu arasindaki iliski Ozteoporoz Dunyasindan 8:173-177
22. Kocyigit H, Gulseren S, Erol A, Hizli N, Memis A (2003) The reliability and validity of the Turkish version of Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO) Clin Rheumatol 22:18-23
23. Aebi H (1974) Catalase. In: Bergmeyer HU (ed) Methods of Enzymatic Analysis. Academic Press, New York, pp. 673-677
24. Paglia DE, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J Lab Clin Med 70:158-170
25. Esterbauer H, Cheeseman KH (1990) Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. In: Packer L, Glazer AN (eds) Methods in Enzymology: V 186, Oxygen Radicals in Biological Systems. Academic Press, California, pp. 407-421
26. Sun Y, Oberley LW, Li Y (1988) A simple method for clinical assay of superoxide dismutase Clin Chem 34:497-500
27. Cortas NK, Wakid NW (1990) Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method Clin Chem 36:1440-1443
28. Hall TJ, Schaueblin M, Jeker H, Fuller K, Chambers TJ (1995) The role of reactive oxygen intermediates in osteoclastic bone resorption Biochem Biophys Res Commun 207:280-287
29. Steinbeck MJ, Appel WH Jr, Verhoeven AJ, Karnovsky MJ (1994) NADPHoxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone J Cell Biol 126:765-772
30. Muthusami S, Ramachandran I, Muthusamy B, Vasudevan G, Prabhu V, Subramaniam V, Jagadeesan A, Narasimhan S (2005) Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats Clin Chim Acta 360:81-86
31. Jagger CJ, Lean JM, Davies JT, Chambers TJ (2005) Tumor necrosis factor-mediates osteopenia caused by depletion of antioxidants Endocrinology 146:113-118
32. Kim HJ, Chang EJ, Kim HM, Lee SB, Kim HD, Kim GS, Kim HH (2006) Antioxidant α-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-β DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-β ligand and tumor necrosis factor-α Free Rad Bio Med 40:1483-1493
33. Wolf RL, Cauley JA, Pettinger M, Jackson R, Lacroix A, Leboff MS, Lewis CE, Nevitt MC, Simon JA, Stone KL, Wactawski-Wende J (2005) Lack of a relation between vitamin and mineral antioxidants and bone mineral density: Results from the Women's Health Initiative Am J Clin Nutr 82:581-588
34. Hao YJ, Tang Y, Chen FB, Pei FX (2005) Different doses of nitric oxide donor prevent osteoporosis in ovariectomized rats Clin Orthop Rel Res 435:226-231
35. van't Hof RJ, Macphee J, Libouban H, Helfrich MH, Ralston SH (2004) Regulation of bone mass and bone turnover by neuronal nitric oxide synthase Endocrinology 145:5068-5074
36. Caballero-Alias AM, Loveridge N, Lyon A, Das-Gupta V, Pitsillides A, Reeve J (2004) NOS isoforms in adult human osteocytes: Multiple pathways of NO regulation? Calcif Tissue Int 75:78-84
37. Jamal SA, Browner WS, Bauer DC, Cummings SR (1998) Intermittent use of nitrates increases bone mineral density: The study of osteoporotic fractures J Bone Miner Res 13:1755-1759
38. Wimalawansa SJ (2000) Nitroglycerin therapy is as efficacious as standard estrogen replacement therapy (premarin) in prevention of oophorectomy-induced bone loss: A human pilot clinical study J Bone Miner Res 15:2240-2244
39. Baecker N, Boese A, Schoenau E, Gerzer R, Heer M (2005) L-arginine, the natural precursor of NO, is not effective for preventing bone loss in postmenopausal women J Bone Miner Res 20:471-479