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Volumn 24, Issue 12, 2013, Pages 2961-2970

Higher serum uric acid is associated with higher bone mass, lower bone turnover, and lower prevalence of vertebral fracture in healthy postmenopausal women

Author keywords

antioxidant; bone density; osteoporosis; oxidative stress; uric acid

Indexed keywords

OSTEOCALCIN; PROCOLLAGEN; PROCOLLAGEN TYPE 1 C TERMINAL TELOPEPTIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; URIC ACID;

EID: 84890430219     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-013-2377-7     Document Type: Article
Times cited : (112)

References (44)
  • 2
    • 70350623839 scopus 로고    scopus 로고
    • Uric acid and risk of myocardial infarction, stroke and congestive heart failure in 417,734 men and women in the Apolipoprotein MOrtality RISk study (AMORIS)
    • 19563390 10.1111/j.1365-2796.2009.02133.x 1:CAS:528: DC%2BC3cXjsVGnsA%3D%3D
    • Holme I, Aastveit AH, Hammar N, Jungner I, Walldius G (2009) Uric acid and risk of myocardial infarction, stroke and congestive heart failure in 417,734 men and women in the Apolipoprotein MOrtality RISk study (AMORIS). J Intern Med 266:558-570
    • (2009) J Intern Med , vol.266 , pp. 558-570
    • Holme, I.1    Aastveit, A.H.2    Hammar, N.3    Jungner, I.4    Walldius, G.5
  • 3
    • 54949100735 scopus 로고    scopus 로고
    • Uric acid and cardiovascular risk
    • 18946066 10.1056/NEJMra0800885 1:CAS:528:DC%2BD1cXht12nu7bI
    • Feig DI, Kang DH, Johnson RJ (2008) Uric acid and cardiovascular risk. N Engl J Med 359:1811-1821
    • (2008) N Engl J Med , vol.359 , pp. 1811-1821
    • Feig, D.I.1    Kang, D.H.2    Johnson, R.J.3
  • 4
    • 34247498150 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome in individuals with hyperuricemia
    • 17466656 10.1016/j.amjmed.2006.06.040
    • Choi HK, Ford ES (2007) Prevalence of the metabolic syndrome in individuals with hyperuricemia. Am J Med 120:442-447
    • (2007) Am J Med , vol.120 , pp. 442-447
    • Choi, H.K.1    Ford, E.S.2
  • 5
    • 0027160479 scopus 로고
    • Towards the physiological function of uric acid
    • 8325534 10.1016/0891-5849(93)90143-I 1:CAS:528:DyaK3sXlslOqu7k%3D
    • Becker BF (1993) Towards the physiological function of uric acid. Free Radic Biol Med 14:615-631
    • (1993) Free Radic Biol Med , vol.14 , pp. 615-631
    • Becker, B.F.1
  • 6
    • 46749114345 scopus 로고    scopus 로고
    • Uric acid: The oxidant-antioxidant paradox
    • 18600514 10.1080/15257770802138558 1:CAS:528:DC%2BD1cXotFelt7c%3D
    • Sautin YY, Johnson RJ (2008) Uric acid: the oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids 27:608-619
    • (2008) Nucleosides Nucleotides Nucleic Acids , vol.27 , pp. 608-619
    • Sautin, Y.Y.1    Johnson, R.J.2
  • 7
    • 1642484244 scopus 로고    scopus 로고
    • Xanthine oxidoreductase and cardiovascular disease: Molecular mechanisms and pathophysiological implications
    • 14694147 10.1113/jphysiol.2003.055913 1:CAS:528:DC%2BD2cXivFCmsbs%3D
    • Berry CE, Hare JM (2004) Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications. J Physiol 555:589-606
    • (2004) J Physiol , vol.555 , pp. 589-606
    • Berry, C.E.1    Hare, J.M.2
  • 8
    • 38749102729 scopus 로고    scopus 로고
    • Is uric acid itself a player or a bystander in the pathophysiology of chronic heart failure?
    • 17689199 10.1016/j.mehy.2007.06.018 1:CAS:528:DC%2BD1cXhslart7o%3D
    • Duan X, Ling F (2008) Is uric acid itself a player or a bystander in the pathophysiology of chronic heart failure? Med Hypotheses 70:578-581
    • (2008) Med Hypotheses , vol.70 , pp. 578-581
    • Duan, X.1    Ling, F.2
  • 9
    • 0037058827 scopus 로고    scopus 로고
    • Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: Role of xanthine-oxidase and extracellular superoxide dismutase
    • 12473554 10.1161/01.CIR.0000041431.57222.AF 1:CAS:528: DC%2BD38XptFKgsLo%3D
    • Landmesser U, Spiekermann S, Dikalov S, Tatge H, Wilke R, Kohler C, Harrison DG, Hornig B, Drexler H (2002) Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase. Circulation 106:3073-3078
    • (2002) Circulation , vol.106 , pp. 3073-3078
    • Landmesser, U.1    Spiekermann, S.2    Dikalov, S.3    Tatge, H.4    Wilke, R.5    Kohler, C.6    Harrison, D.G.7    Hornig, B.8    Drexler, H.9
  • 11
    • 0037024270 scopus 로고    scopus 로고
    • Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: Results from 2 placebo-controlled studies
    • 12045167 10.1161/01.CIR.0000017502.58595.ED 1:CAS:528: DC%2BD38XltFantr0%3D
    • Doehner W, Schoene N, Rauchhaus M, Leyva-Leon F, Pavitt DV, Reaveley DA, Schuler G, Coats AJ, Anker SD, Hambrecht R (2002) Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies. Circulation 105:2619-2624
    • (2002) Circulation , vol.105 , pp. 2619-2624
    • Doehner, W.1    Schoene, N.2    Rauchhaus, M.3    Leyva-Leon, F.4    Pavitt, D.V.5    Reaveley, D.A.6    Schuler, G.7    Coats, A.J.8    Anker, S.D.9    Hambrecht, R.10
  • 12
    • 0034888485 scopus 로고    scopus 로고
    • Systemic uric acid administration increases serum antioxidant capacity in healthy volunteers
    • 10.1097/00005344-200109000-00005 1:CAS:528:DC%2BD3MXmtFKktLY%3D
    • Waring WS, Webb DJ, Maxwell SRJ (2001) Systemic uric acid administration increases serum antioxidant capacity in healthy volunteers. J Cardiovasc Pharm 38:365-371
    • (2001) J Cardiovasc Pharm , vol.38 , pp. 365-371
    • Waring, W.S.1    Webb, D.J.2    Maxwell, S.R.J.3
  • 14
    • 84867330990 scopus 로고    scopus 로고
    • Uric acid levels predict survival in men with amyotrophic lateral sclerosis
    • 22323210 10.1007/s00415-012-6440-7 1:CAS:528:DC%2BC38XhtlWqs7jF
    • Paganoni S, Zhang M, Quiroz Zarate A, Jaffa M, Yu H, Cudkowicz ME, Wills AM (2012) Uric acid levels predict survival in men with amyotrophic lateral sclerosis. J Neurol 259:1923-1928
    • (2012) J Neurol , vol.259 , pp. 1923-1928
    • Paganoni, S.1    Zhang, M.2    Quiroz Zarate, A.3    Jaffa, M.4    Yu, H.5    Cudkowicz, M.E.6    Wills, A.M.7
  • 15
    • 0025236484 scopus 로고
    • Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo
    • 2312718 10.1172/JCI114485 1:CAS:528:DyaK3cXhslaktrs%3D
    • Garrett IR, Boyce BF, Oreffo RO, Bonewald L, Poser J, Mundy GR (1990) Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest 85:632-639
    • (1990) J Clin Invest , vol.85 , pp. 632-639
    • Garrett, I.R.1    Boyce, B.F.2    Oreffo, R.O.3    Bonewald, L.4    Poser, J.5    Mundy, G.R.6
  • 16
    • 8644225111 scopus 로고    scopus 로고
    • Reactive oxygen species mediate RANK signaling in osteoclasts
    • 15530848 10.1016/j.yexcr.2004.07.035 1:CAS:528:DC%2BD2cXpsVOksLw%3D
    • Ha H, Kwak HB, Lee SW, Jin HM, Kim HM, Kim HH, Lee ZH (2004) Reactive oxygen species mediate RANK signaling in osteoclasts. Exp Cell Res 301:119-127
    • (2004) Exp Cell Res , vol.301 , pp. 119-127
    • Ha, H.1    Kwak, H.B.2    Lee, S.W.3    Jin, H.M.4    Kim, H.M.5    Kim, H.H.6    Lee, Z.H.7
  • 17
    • 0347356247 scopus 로고    scopus 로고
    • Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-kappa B
    • 10.1016/j.bbrc.2003.12.073 1:CAS:528:DC%2BD2cXjtVeisA%3D%3D
    • Bai XC, Lu D, Bai J, Zheng H, Ke ZY, Li XM, Luo SQ (2004) Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-kappa B. Biochem Bioph Res Co 314:197-207
    • (2004) Biochem Bioph Res Co , vol.314 , pp. 197-207
    • Bai, X.C.1    Lu, D.2    Bai, J.3    Zheng, H.4    Ke, Z.Y.5    Li, X.M.6    Luo, S.Q.7
  • 18
    • 26444485498 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in hydrogen peroxide-induced cell death in osteoblastic cells
    • 16125295 10.1016/j.tox.2005.07.003 1:CAS:528:DC%2BD2MXhtVymsbjL
    • Park BG, Yoo CI, Kim HT, Kwon CH, Kim YK (2005) Role of mitogen-activated protein kinases in hydrogen peroxide-induced cell death in osteoblastic cells. Toxicology 215:115-125
    • (2005) Toxicology , vol.215 , pp. 115-125
    • Park, B.G.1    Yoo, C.I.2    Kim, H.T.3    Kwon, C.H.4    Kim, Y.K.5
  • 20
    • 38849088768 scopus 로고    scopus 로고
    • Oxidative stress as a risk factor for osteoporosis in elderly Mexicans as characterized by antioxidant enzymes
    • 18088440 10.1186/1471-2474-8-124
    • Sánchez-Rodríguez M, Ruiz-Ramos M, Correa-Muñoz E, Mendoza-Núñez V (2007) Oxidative stress as a risk factor for osteoporosis in elderly Mexicans as characterized by antioxidant enzymes. BMC Musculoskelet Disord 8:124
    • (2007) BMC Musculoskelet Disord , vol.8 , pp. 124
    • Sánchez-Rodríguez, M.1    Ruiz-Ramos, M.2    Correa-Muñoz, E.3    Mendoza-Núñez, V.4
  • 21
    • 0036184271 scopus 로고    scopus 로고
    • A duality in the roles of reactive oxygen species with respect to bone metabolism
    • 11880125 10.1016/S0009-8981(01)00766-5 1:CAS:528:DC%2BD38XhslWjtrg%3D
    • Sontakke AN, Tare RS (2002) A duality in the roles of reactive oxygen species with respect to bone metabolism. Clin Chim Acta 318:145-148
    • (2002) Clin Chim Acta , vol.318 , pp. 145-148
    • Sontakke, A.N.1    Tare, R.S.2
  • 22
    • 0031865039 scopus 로고    scopus 로고
    • The relation of dietary vitamin C intake to bone mineral density: Results from the PEPI study
    • 9701620 10.1007/s002239900512 1:CAS:528:DyaK1cXlvFWks7s%3D
    • Hall SL, Greendale GA (1998) The relation of dietary vitamin C intake to bone mineral density: results from the PEPI study. Calcif Tissue Int 63:183-189
    • (1998) Calcif Tissue Int , vol.63 , pp. 183-189
    • Hall, S.L.1    Greendale, G.A.2
  • 23
    • 0345390062 scopus 로고    scopus 로고
    • Smoking, antioxidant vitamins, and the risk of hip fracture
    • 9893075 10.1359/jbmr.1999.14.1.129 1:STN:280:DyaK1M7htFaksA%3D%3D
    • Melhus H, Michaelsson K, Holmberg L, Wolk A, Ljunghall S (1999) Smoking, antioxidant vitamins, and the risk of hip fracture. J Bone Miner Res 14:129-135
    • (1999) J Bone Miner Res , vol.14 , pp. 129-135
    • Melhus, H.1    Michaelsson, K.2    Holmberg, L.3    Wolk, A.4    Ljunghall, S.5
  • 24
    • 33845352241 scopus 로고    scopus 로고
    • Lycopene consumption decreases oxidative stress and bone resorption markers in postmenopausal women
    • 10.1007/s00198-006-0205-z 1:CAS:528:DC%2BD28Xht1OhtrfN
    • Rao L, Mackinnon E, Josse R, Murray T, Strauss A, Rao A (2007) Lycopene consumption decreases oxidative stress and bone resorption markers in postmenopausal women. Osteoporosis Int 18:109-115
    • (2007) Osteoporosis Int , vol.18 , pp. 109-115
    • Rao, L.1    Mackinnon, E.2    Josse, R.3    Murray, T.4    Strauss, A.5    Rao, A.6
  • 25
    • 79953329381 scopus 로고    scopus 로고
    • Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type i collagen in postmenopausal women
    • 10.1007/s00198-010-1308-0 1:CAS:528:DC%2BC3MXisFersL8%3D
    • Mackinnon E, Rao A, Josse R, Rao L (2011) Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type I collagen in postmenopausal women. Osteoporosis Int 22:1091-1101
    • (2011) Osteoporosis Int , vol.22 , pp. 1091-1101
    • Mackinnon, E.1    Rao, A.2    Josse, R.3    Rao, L.4
  • 27
    • 77958476361 scopus 로고    scopus 로고
    • Moderate levels of plasma uric acid could promote fracture healing
    • 20800369 10.1016/j.mehy.2010.07.054 1:CAS:528:DC%2BC3cXhtlCgtr3M
    • Donghui MM (2010) Moderate levels of plasma uric acid could promote fracture healing. Med Hypotheses 75:682
    • (2010) Med Hypotheses , vol.75 , pp. 682
    • Donghui, M.M.1
  • 28
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • 1244564 10.1159/000180580 1:STN:280:DyaE28%2FnsF2isw%3D%3D
    • Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16:31-41
    • (1976) Nephron , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 29
    • 0028902387 scopus 로고
    • Assessing vertebral fractures. National Osteoporosis Foundation Working Group on Vertebral Fractures
    • 7610921 1:STN:280:DyaK2MzjsFejsg%3D%3D
    • Kiel D (1995) Assessing vertebral fractures. National Osteoporosis Foundation Working Group on Vertebral Fractures. J Bone Miner Res 10:518-523
    • (1995) J Bone Miner Res , vol.10 , pp. 518-523
    • Kiel, D.1
  • 30
    • 0027219544 scopus 로고
    • Vertebral fracture assessment using a semiquantitative technique
    • 8237484 10.1002/jbmr.5650080915 1:STN:280:DyaK2c%2FlsFyhuw%3D%3D
    • Genant HK, Wu CY, van Kuijk C, Nevitt MC (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8:1137-1148
    • (1993) J Bone Miner Res , vol.8 , pp. 1137-1148
    • Genant, H.K.1    Wu, C.Y.2    Van Kuijk, C.3    Nevitt, M.C.4
  • 31
    • 0021108985 scopus 로고
    • Parathyroid function and uric acid metabolism
    • 6667755 1:STN:280:DyaL2c7jt1Ogtw%3D%3D
    • Yoneda M, Takatsuki K, Tomita A (1983) Parathyroid function and uric acid metabolism. Nihon Naibunpi Gakkai Zasshi 59:1738-1751
    • (1983) Nihon Naibunpi Gakkai Zasshi , vol.59 , pp. 1738-1751
    • Yoneda, M.1    Takatsuki, K.2    Tomita, A.3
  • 32
    • 84862793024 scopus 로고    scopus 로고
    • The independent association between parathyroid hormone levels and hyperuricemia: A national population study
    • 10.1186/ar3769 22405053 10.1186/ar3769 1:CAS:528:DC%2BC38XnsV2nsbo%3D
    • Hui JY, Choi JW, Mount DB, Zhu Y, Zhang Y, Choi HK (2012) The independent association between parathyroid hormone levels and hyperuricemia: a national population study. Arthritis Res Ther 14:R56. doi: 10.1186/ar3769
    • (2012) Arthritis Res Ther , vol.14 , pp. 56
    • Hui, J.Y.1    Choi, J.W.2    Mount, D.B.3    Zhu, Y.4    Zhang, Y.5    Choi, H.K.6
  • 33
    • 44849091923 scopus 로고    scopus 로고
    • Safety of parathyroid hormone for the treatment of osteoporosis
    • 18430395 10.1007/s11914-008-0003-y
    • Miller PD (2008) Safety of parathyroid hormone for the treatment of osteoporosis. Curr Osteoporos Rep 6:12-16
    • (2008) Curr Osteoporos Rep , vol.6 , pp. 12-16
    • Miller, P.D.1
  • 34
    • 0031934648 scopus 로고    scopus 로고
    • Decreased serum concentrations of 1,25(OH)2-vitamin D3 in patients with gout
    • 9500573 10.1016/S0026-0495(98)90267-0 1:CAS:528:DyaK1cXhsFynsbo%3D
    • Takahashi S, Yamamoto T, Moriwaki Y, Tsutsumi Z, Yamakita J, Higashino K (1998) Decreased serum concentrations of 1,25(OH)2-vitamin D3 in patients with gout. Metabolism 47:336-338
    • (1998) Metabolism , vol.47 , pp. 336-338
    • Takahashi, S.1    Yamamoto, T.2    Moriwaki, Y.3    Tsutsumi, Z.4    Yamakita, J.5    Higashino, K.6
  • 35
    • 0027671797 scopus 로고
    • Effect of uric acid on plasma levels of 1,25(OH)2D in renal failure
    • 8286711 1:STN:280:DyaK2c7hsVyrtg%3D%3D
    • Vanholder R, Patel S, Hsu CH (1993) Effect of uric acid on plasma levels of 1,25(OH)2D in renal failure. J Am Soc Nephrol 4:1035-1038
    • (1993) J Am Soc Nephrol , vol.4 , pp. 1035-1038
    • Vanholder, R.1    Patel, S.2    Hsu, C.H.3
  • 37
    • 12344281693 scopus 로고    scopus 로고
    • Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation
    • 15528306 10.1210/en.2004-1021 1:CAS:528:DC%2BD2MXotlWhtw%3D%3D
    • Lean JM, Jagger CJ, Kirstein B, Fuller K, Chambers TJ (2005) Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation. Endocrinology 146:728-735
    • (2005) Endocrinology , vol.146 , pp. 728-735
    • Lean, J.M.1    Jagger, C.J.2    Kirstein, B.3    Fuller, K.4    Chambers, T.J.5
  • 38
    • 84859593877 scopus 로고    scopus 로고
    • Effects of vitamin e on bone turnover markers among US postmenopausal women
    • 22308007 10.1002/jbmr.1566 1:CAS:528:DC%2BC38XntFSgsro%3D
    • Hamidi MS, Corey PN, Cheung AM (2012) Effects of vitamin E on bone turnover markers among US postmenopausal women. J Bone Miner Res 27:1368-1380
    • (2012) J Bone Miner Res , vol.27 , pp. 1368-1380
    • Hamidi, M.S.1    Corey, P.N.2    Cheung, A.M.3
  • 40
    • 11144248825 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha mediates osteopenia caused by depletion of antioxidants
    • 15388652 10.1210/en.2004-1058 1:CAS:528:DC%2BD2cXhtFGmt7jL
    • Jagger CJ, Lean JM, Davies JT, Chambers TJ (2005) Tumor necrosis factor-alpha mediates osteopenia caused by depletion of antioxidants. Endocrinology 146:113-118
    • (2005) Endocrinology , vol.146 , pp. 113-118
    • Jagger, C.J.1    Lean, J.M.2    Davies, J.T.3    Chambers, T.J.4
  • 42
    • 84868678259 scopus 로고    scopus 로고
    • Serum uric acid plays a protective role for bone loss in peri- and postmenopausal women: A longitudinal study
    • 23111314 10.1016/j.bone.2012.10.025 1:CAS:528:DC%2BC38XhvVSlt77J
    • Makovey J, Macara M, Chen JS, Hayward CS, March L, Seibel MJ, Sambrook PN (2013) Serum uric acid plays a protective role for bone loss in peri- and postmenopausal women: a longitudinal study. Bone 52:400-406
    • (2013) Bone , vol.52 , pp. 400-406
    • Makovey, J.1    Macara, M.2    Chen, J.S.3    Hayward, C.S.4    March, L.5    Seibel, M.J.6    Sambrook, P.N.7
  • 43
    • 67349152809 scopus 로고    scopus 로고
    • Bone turnover markers in the management of postmenopausal osteoporosis
    • 19362543 10.1016/j.clinbiochem.2009.04.001 1:CAS:528:DC%2BD1MXnt1emt74%3D
    • Brown JP, Albert C, Nassar BA et al (2009) Bone turnover markers in the management of postmenopausal osteoporosis. Clin Biochem 42:929-942
    • (2009) Clin Biochem , vol.42 , pp. 929-942
    • Brown, J.P.1    Albert, C.2    Nassar, B.A.3
  • 44
    • 84859861002 scopus 로고    scopus 로고
    • The prevalence and risk factors of vertebral fractures in Korea
    • 21773702 10.1007/s00774-011-0300-x
    • Shin CS, Kim MJ, Shim SM et al (2012) The prevalence and risk factors of vertebral fractures in Korea. J Bone Miner Metab 30:183-192
    • (2012) J Bone Miner Metab , vol.30 , pp. 183-192
    • Shin, C.S.1    Kim, M.J.2    Shim, S.M.3


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