LC3 binds externalized cardiolipin on injured mitochondria to signal mitophagy in neurons: Implications for Parkinson disease

Autophagy

Volumn 10, Issue 2, 2014, Pages 376-378

  Chu, Charleen T ^a   Bayir, Hülya ^b,c   Kagan, Valerian E ^c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

6 Hydroxydopamine; Autophagy; Cardiolipin; Cargo recognition; MAP1 LC3; Mitophagy; Neurodegenerative diseases; Neurons; Parkinson; Rotenone

Indexed keywords

CARDIOLIPIN; LIGHT CHAIN 3 PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1; OXIDOPAMINE; PROTEIN; ROTENONE; UNCLASSIFIED DRUG;

AUTOPHAGOSOME; BRAIN CELL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON TRANSPORT; HUMAN; INTRACELLULAR SIGNALING; LIPIDOMICS; LYSOSOME; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION DAMAGE; MITOPHAGY; PARKINSON DISEASE; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SHORT SURVEY; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

6-HYDROXYDOPAMINE; AUTOPHAGY; CARDIOLIPIN; CARGO RECOGNITION; MAP1-LC3; MITOPHAGY; NEURODEGENERATIVE DISEASES; NEURONS; PARKINSON; ROTENONE;

ANIMALS; AUTOPHAGY; CARDIOLIPINS; CELLS, CULTURED; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; NEURONS; PARKINSON DISEASE; PROTEIN BINDING; RATS; SIGNAL TRANSDUCTION;

EID: 84894490723     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.27191     Document Type: Short Survey

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