Integrins: Therapeutic targets in airway hyperresponsiveness and remodelling?

Trends in Pharmacological Sciences

Volumn 35, Issue 11, 2014, Pages 567-574

  Wright, David B ^a,b   Meurs, Herman ^a,b   Dekkers, Bart G J ^b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

airway fibroblast; airway hyperresponsiveness; airway remodeling; airway smooth muscle; integrin

Indexed keywords

ALPHAVBETA5 INTEGRIN; BETA1 INTEGRIN; INTEGRIN; VITRONECTIN RECEPTOR; ANTIASTHMATIC AGENT; BRONCHODILATING AGENT;

AIRWAY REMODELING; BINDING AFFINITY; CELL INTERACTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; LUNG ALVEOLUS WALL; MAST CELL; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; REVIEW; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; ANIMAL; ASTHMA; BRONCHIAL HYPERREACTIVITY; DRUG EFFECTS; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

AIRWAY REMODELING; ANIMALS; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHODILATOR AGENTS; HUMANS; INTEGRINS; MOLECULAR TARGETED THERAPY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84908371488     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2014.09.006     Document Type: Review

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