메뉴 건너뛰기




Volumn 38, Issue 2, 2011, Pages 318-328

Increased arginase activity contributes to airway remodelling in chronic allergic asthma

Author keywords

Airway hyperresponsiveness; Airway remodelling; Eosinophils; Fibrosis; Goblet cells; Polyamines

Indexed keywords

2 AMINO 6 BORONOHEXANOIC ACID; ARGINASE; CITRULLINE; HYDROLASE INHIBITOR; HYDROXYPROLINE; INTERLEUKIN 13; METHACHOLINE; ORNITHINE; OVALBUMIN; PUTRESCINE; UNCLASSIFIED DRUG;

EID: 80051531018     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00057710     Document Type: Article
Times cited : (84)

References (56)
  • 2
    • 33748046456 scopus 로고    scopus 로고
    • Mechanisms of airway hyperresponsiveness
    • DOI 10.1016/j.jaci.2006.07.012, PII S0091674906015119
    • Cockcroft DW, Davis BE. Mechanisms of airway hyperresponsiveness. J Allergy Clin Immunol 2006; 118: 551-559. (Pubitemid 44301418)
    • (2006) Journal of Allergy and Clinical Immunology , vol.118 , Issue.3 , pp. 551-559
    • Cockcroft, D.W.1    Davis, B.E.2
  • 3
    • 56149111462 scopus 로고    scopus 로고
    • Airway hyperresponsiveness in asthma: Lessons from in vitro model systems and animal models
    • Meurs H, Gosens R, Zaagsma J. Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models. Eur Respir J 2008; 32: 487-502.
    • (2008) Eur Respir J , vol.32 , pp. 487-502
    • Meurs, H.1    Gosens, R.2    Zaagsma, J.3
  • 4
    • 70350051180 scopus 로고    scopus 로고
    • Arginase: A key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives
    • Maarsingh H, Zaagsma J, Meurs H. Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives. Br J Pharmacol 2009; 158: 652-664.
    • (2009) Br J Pharmacol , vol.158 , pp. 652-664
    • Maarsingh, H.1    Zaagsma, J.2    Meurs, H.3
  • 5
    • 0032533159 scopus 로고    scopus 로고
    • Arginine metabolism: Nitric oxide and beyond
    • Wu G, Morris SM. Arginine metabolism: nitric oxide and beyond. Biochem J 1998; 336: 1-17. (Pubitemid 28532555)
    • (1998) Biochemical Journal , vol.336 , Issue.1 , pp. 1-17
    • Wu, G.1    Morris Jr., S.M.2
  • 6
    • 0031867925 scopus 로고    scopus 로고
    • Induction of arginase isoforms in the lung during hyperoxia
    • Que LG, Kantrow SP, Jenkinson CP, et al. Induction of arginase isoforms in the lung during hyperoxia. Am J Physiol 1998; 275: L96-L102.
    • (1998) Am J Physiol , vol.275
    • Que, L.G.1    Kantrow, S.P.2    Jenkinson, C.P.3
  • 8
    • 0347991779 scopus 로고    scopus 로고
    • Glucocorticoid inhibition of interleukin-4 (IL-4) and interleukin-13 (IL-13) induced up-regulation of arginase in rat airway fibroblasts
    • DOI 10.1007/s00210-003-0839-8
    • Lindemann D, Racke K. Glucocorticoid inhibition of interleukin-4 (IL-4) and interleukin-13 (IL-13) induced up-regulation of arginase in rat airway fibroblasts. Naunyn Schmiedebergs Arch Pharmacol 2003; 368: 546-550. (Pubitemid 38041319)
    • (2003) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.368 , Issue.6 , pp. 546-550
    • Lindemann, D.1    Racke, K.2
  • 11
    • 67049156045 scopus 로고    scopus 로고
    • Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma
    • North ML, Khanna N, Marsden PA, et al. Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma. Am J Physiol Lung Cell Mol Physiol 2009; 296: L911-L920.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296
    • North, M.L.1    Khanna, N.2    Marsden, P.A.3
  • 14
    • 32844458380 scopus 로고    scopus 로고
    • Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma
    • Maarsingh H, Leusink J, Bos IST, et al. Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma. Respir Res 2006; 7: 6.
    • (2006) Respir Res , vol.7 , pp. 6
    • Maarsingh, H.1    Leusink, J.2    Bos, I.S.T.3
  • 15
    • 69249138275 scopus 로고    scopus 로고
    • L-Arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction
    • Maarsingh H, Bossenga BE, Bos IST, et al. L-Arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction. Eur Respir J 2009; 34: 191-199.
    • (2009) Eur Respir J , vol.34 , pp. 191-199
    • Maarsingh, H.1    Bossenga, B.E.2    Bos, I.S.T.3
  • 16
    • 0034864110 scopus 로고    scopus 로고
    • Role of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigs
    • De Boer J, Meurs H, Flendrig L, et al. Role of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigs. Br J Pharmacol 2001; 133: 1235-1242. (Pubitemid 32783483)
    • (2001) British Journal of Pharmacology , vol.133 , Issue.8 , pp. 1235-1242
    • De Boer, J.1    Meurs, H.2    Flendrig, L.3    Koopal, M.4    Zaagsma, J.5
  • 18
    • 0031889192 scopus 로고    scopus 로고
    • Role of nitric oxide in the development and partial reversal of allergen-induced airway hyperreactivity in conscious, unrestrained guinea-pigs
    • DOI 10.1038/sj.bjp.0701738
    • Schuiling M, Zuidhof AB, Bonouvrie MA, et al. Role of nitric oxide in the development and partial reversal of allergen-induced airway hyperreactivity in conscious, unrestrained guinea-pigs. Br J Pharmacol 1998; 123: 1450-1456. (Pubitemid 28143147)
    • (1998) British Journal of Pharmacology , vol.123 , Issue.7 , pp. 1450-1456
    • Schuiling, M.1    Zuidhof, A.B.2    Bonouvrie, M.A.A.3    Venema, N.4    Zaagsma, J.5    Meurs, H.6
  • 19
    • 51849107399 scopus 로고    scopus 로고
    • Arginase inhibition protects against allergic airway obstruction, hyperresponsiveness and inflammation
    • Maarsingh H, Zuidhof AB, Bos IS, et al. Arginase inhibition protects against allergic airway obstruction, hyperresponsiveness and inflammation. Am J Respir Crit Care Med 2008; 178: 565-573.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 565-573
    • Maarsingh, H.1    Zuidhof, A.B.2    Bos, I.S.3
  • 20
    • 0032761976 scopus 로고    scopus 로고
    • Antiproliferative effects of NO and ANP in cultured human airway smooth muscle
    • Hamad AM, Johnson SR, Knox AJ. Antiproliferative effects of NO and ANP in cultured human airway smooth muscle. Am J Physiol 1999; 277: L910-L918.
    • (1999) Am J Physiol , vol.277
    • Hamad, A.M.1    Johnson, S.R.2    Knox, A.J.3
  • 21
    • 0035812908 scopus 로고    scopus 로고
    • Mechanisms mediating the antiproliferative effects of nitric oxide in cultured human airway smooth muscle cells
    • DOI 10.1016/S0014-5793(01)02883-6, PII S0014579301028836
    • Hamad AM, Knox AJ. Mechanisms mediating the antiproliferative effects of nitric oxide in cultured human airway smooth muscle cells. FEBS Lett 2001; 506: 91-96. (Pubitemid 32925206)
    • (2001) FEBS Letters , vol.506 , Issue.2 , pp. 91-96
    • Hamad, A.M.1    Knox, A.J.2
  • 22
    • 0032863165 scopus 로고    scopus 로고
    • Constitutive expressions of type I NOS in human airway smooth muscle cells: Evidence for an antiproliferative role
    • Patel HJ, Belvisi MG, Donnelly LE, et al. Constitutive expressions of type I NOS in human airway smooth muscle cells: evidence for an antiproliferative role. FASEB J 1999; 13: 1810-1816. (Pubitemid 29473343)
    • (1999) FASEB Journal , vol.13 , Issue.13 , pp. 1810-1816
    • Patel, H.J.1    Belvisi, M.G.2    Donnelly, L.E.3    Yacoub, M.H.4    Chung, K.F.5    Mitchell, J.A.6
  • 24
    • 34249001283 scopus 로고    scopus 로고
    • Nitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells
    • DOI 10.1515/BC.2007.056
    • Wani J, Carl M, Henger A, et al. Nitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells. Biol Chem 2007; 388: 497-506. (Pubitemid 46800261)
    • (2007) Biological Chemistry , vol.388 , Issue.5 , pp. 497-506
    • Wani, J.1    Carl, M.2    Henger, A.3    Nelson, P.J.4    Rupprecht, H.5
  • 25
    • 0041878667 scopus 로고    scopus 로고
    • Arginase and asthma: Novel insights into nitric oxide homeostasis and airway hyperresponsiveness
    • DOI 10.1016/S0165-6147(03)00227-X
    • Meurs H, Maarsingh H, Zaagsma J. Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness. Trends Pharmacol Sci 2003; 24: 450-455. (Pubitemid 37088169)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.9 , pp. 450-455
    • Meurs, H.1    Maarsingh, H.2    Zaagsma, J.3
  • 27
    • 40749116960 scopus 로고    scopus 로고
    • Functional role and species-specific contribution of arginases in pulmonary fibrosis
    • Kitowska K, Zakrzewicz D, Konigshoff M, et al. Functional role and species-specific contribution of arginases in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 2007; 294: L34-L45.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Kitowska, K.1    Zakrzewicz, D.2    Konigshoff, M.3
  • 28
    • 70350075426 scopus 로고    scopus 로고
    • Increased arginase activity underlies airway hyperresponsiveness in a guinea pig model of chronic allergic asthma
    • Maarsingh H, Bos IST, Westerhof-Humblot FJ, et al. Increased arginase activity underlies airway hyperresponsiveness in a guinea pig model of chronic allergic asthma. Am J Respir Crit Care Med 2007; 175: A522.
    • (2007) Am J Respir Crit Care Med , vol.175
    • Maarsingh, H.1    Bos, I.S.T.2    Westerhof-Humblot, F.J.3
  • 29
    • 34548751788 scopus 로고    scopus 로고
    • A guinea pig model of acute and chronic asthma using permanently instrumented and unrestrained animals
    • Meurs H, Santing RE, Remie R, et al. A guinea pig model of acute and chronic asthma using permanently instrumented and unrestrained animals. Nat Protoc 2006; 1: 840-847.
    • (2006) Nat Protoc , vol.1 , pp. 840-847
    • Meurs, H.1    Santing, R.E.2    Remie, R.3
  • 33
    • 0023902325 scopus 로고
    • Osmotic stimuli induce epithelial-dependent relaxation in the guinea pig trachea
    • Munakata M, Mitzner W, Menkes H. Osmotic stimuli induce epithelial-dependent relaxation in guinea pig trachea. J Appl Physiol 1988; 64: 466-471. (Pubitemid 18042269)
    • (1988) Journal of Applied Physiology , vol.64 , Issue.1 , pp. 466-471
    • Munakata, M.1    Mitzner, W.2    Menkes, H.3
  • 34
    • 77749324374 scopus 로고    scopus 로고
    • The integrin-blocking peptide RGDS inhibits airway smooth muscle remodeling in a guinea pig model of allergic asthma
    • Dekkers BG, Bos IS, Gosens R, et al. The integrin-blocking peptide RGDS inhibits airway smooth muscle remodeling in a guinea pig model of allergic asthma. Am J Respir Crit Care Med 2010; 181: 556-565.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 556-565
    • Dekkers, B.G.1    Bos, I.S.2    Gosens, R.3
  • 36
    • 0035891664 scopus 로고    scopus 로고
    • Remodeling in asthma and chronic obstructive lung disease
    • Jeffery PK. Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 2001; 164: S28-S38.
    • (2001) Am J Respir Crit Care Med , vol.164
    • Jeffery, P.K.1
  • 37
    • 33745855449 scopus 로고    scopus 로고
    • Remodeling in asthma and chronic obstructive pulmonary disease
    • DOI 10.1513/pats.200601-006AW
    • Postma DS, Timens W. Remodeling in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3: 434-439. (Pubitemid 44033359)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.5 , pp. 434-439
    • Postma, D.S.1    Timens, W.2
  • 38
    • 77953522851 scopus 로고    scopus 로고
    • Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model
    • Takahashi N, Ogino K, Takemoto K, et al. Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model. Am J Physiol Lung Cell Mol Physiol 2010; 299: L17-L24.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299
    • Takahashi, N.1    Ogino, K.2    Takemoto, K.3
  • 39
    • 74849084373 scopus 로고    scopus 로고
    • Airway structural components drive airway smooth muscle remodeling in asthma
    • Dekkers BG, Maarsingh H, Meurs H, et al. Airway structural components drive airway smooth muscle remodeling in asthma. Proc Am Thorac Soc 2009; 6: 683-692.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 683-692
    • Dekkers, B.G.1    Maarsingh, H.2    Meurs, H.3
  • 44
    • 57049148700 scopus 로고    scopus 로고
    • Peroxynitrite augments fibroblast-mediated tissue remodeling via myofibroblast differentiation
    • Ichikawa T, Sugiura H, Koarai A, et al. Peroxynitrite augments fibroblast-mediated tissue remodeling via myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol 2008; 295: L800-L808.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295
    • Ichikawa, T.1    Sugiura, H.2    Koarai, A.3
  • 45
    • 20544468146 scopus 로고    scopus 로고
    • Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway
    • DOI 10.1111/j.1600-6143.2005.00876.x
    • Liu H, Drew P, Gaugler AC, et al. Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway. Am J Transplant 2005; 5: 1256-1263. (Pubitemid 40839413)
    • (2005) American Journal of Transplantation , vol.5 , Issue.6 , pp. 1256-1263
    • Liu, H.1    Drew, P.2    Gaugler, A.C.3    Cheng, Y.4    Visner, G.A.5
  • 48
    • 0043065288 scopus 로고    scopus 로고
    • Susceptibility to ovalbumin-induced airway inflammation and fibrosis in inducible nitric oxide synthetase-deficient mice: Mechanisms and consequences
    • DOI 10.1016/S0041-008X(03)00227-8
    • Kenyon NJ, Gohil K, Last JA. Susceptibility to ovalbumin-induced airway inflammation and fibrosis in inducible nitric oxide synthetase-deficient mice: mechanisms and consequences. Toxicol Appl Pharmacol 2003; 191: 2-11. (Pubitemid 36959959)
    • (2003) Toxicology and Applied Pharmacology , vol.191 , Issue.1 , pp. 2-11
    • Kenyon, N.J.1    Gohil, K.2    Last, J.A.3
  • 49
    • 33646243784 scopus 로고    scopus 로고
    • Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice
    • Ten Broeke R, De Crom R, Van Haperen R, et al. Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice. Respir Res 2006; 7: 58.
    • (2006) Respir Res , vol.7 , pp. 58
    • Ten Broeke, R.1    De Crom, R.2    Van Haperen, R.3
  • 50
    • 58649121269 scopus 로고    scopus 로고
    • Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin
    • Bratt JM, Franzi LM, Linderholm AL, et al. Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin. Toxicol Appl Pharmacol 2009; 234: 273-280.
    • (2009) Toxicol Appl Pharmacol , vol.234 , pp. 273-280
    • Bratt, J.M.1    Franzi, L.M.2    Linderholm, A.L.3
  • 51
    • 56149107742 scopus 로고    scopus 로고
    • Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration
    • Ckless K, Lampert A, Reiss J, et al. Inhibition of arginase activity enhances inflammation in mice with allergic airway disease, in association with increases in protein S-nitrosylation and tyrosine nitration. J Immunol 2008; 181: 4255-4264.
    • (2008) J Immunol , vol.181 , pp. 4255-4264
    • Ckless, K.1    Lampert, A.2    Reiss, J.3
  • 52
    • 67649604532 scopus 로고    scopus 로고
    • Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice
    • Niese KA, Collier AR, Hajek AR, et al. Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. BMC Immunol 2009; 10: 33.
    • (2009) BMC Immunol , vol.10 , pp. 33
    • Niese, K.A.1    Collier, A.R.2    Hajek, A.R.3
  • 53
    • 36749077948 scopus 로고    scopus 로고
    • Physiology of airway mucus secretion and pathophysiology of hypersecretion
    • Rogers DF. Physiology of airway mucus secretion and pathophysiology of hypersecretion. Respir Care 2007; 52: 1134-1146.
    • (2007) Respir Care , vol.52 , pp. 1134-1146
    • Rogers, D.F.1
  • 55
    • 0029767883 scopus 로고    scopus 로고
    • Nitric oxide inhibition of basal and neurogenic mucus secretion in ferret trachea in vitro
    • Ramnarine SI, Khawaja AM, Barnes PJ, et al. Nitric oxide inhibition of basal and neurogenic mucus secretion in ferret trachea in vitro. Br J Pharmacol 1996; 118: 998-1002. (Pubitemid 26261274)
    • (1996) British Journal of Pharmacology , vol.118 , Issue.4 , pp. 998-1002
    • Ramnarine, S.I.1    Khawaja, A.M.2    Barnes, P.J.3    Rogers, D.F.4
  • 56
    • 0036009464 scopus 로고    scopus 로고
    • Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species
    • Fischer BM, Voynow JA. Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species. Am J Respir Cell Mol Biol 2002; 26: 447-452. (Pubitemid 34253929)
    • (2002) American Journal of Respiratory Cell and Molecular Biology , vol.26 , Issue.4 , pp. 447-452
    • Fischer, B.M.1    Voynow, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.