Plasminogen activation by airway smooth muscle is regulated by type I collagen

American Journal of Respiratory Cell and Molecular Biology

Volumn 44, Issue 6, 2011, Pages 831-839

  Schuliga, Michael ^a   Harris, Trudi ^a   Stewart, Alastair G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Asthma; Fibrosis; Integrin; Plasmin; Urokinase

Indexed keywords

BETA1 INTEGRIN COLLAGEN RECEPTOR; COLLAGEN TYPE 1; PLASMIN; PLASMINOGEN; RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UROKINASE;

AIRWAY SMOOTH MUSCLE CELL; ARTICLE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER;

ANTIGENS, CD29; ASTHMA; CASEINS; COLLAGEN TYPE I; FIBRINOLYSIN; GENE EXPRESSION REGULATION; HUMANS; MODELS, BIOLOGICAL; MUSCLE, SMOOTH; PLASMINOGEN; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 80051563924     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0469OC     Document Type: Article

References (61)

1. Holgate ST, Holloway J, Wilson S, Howarth PH, Haitchi HM, Babu S, Davies DE. Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities. J Allergy Clin Immunol 2006;117:496-506, quiz 507.
2. Amin K, Ludviksdottir D, Janson C, Nettelbladt O, Bjornsson E, Roomans GM, Boman G, Seveus L, Venge P. Inflammation and structural changes in the airways of patients with atopic and nonatopic asthma. BHR group. Am J Respir Crit Care Med 2000;162:2295-2301. (Pubitemid 32051703)
3. Redington AE. Airway fibrosis in asthma: mechanisms, consequences, and potential for therapeutic intervention. Monaldi Arch Chest Dis 2000;55:317-323.
4. Wilson JW, Li X, Pain MC. The lack of distensibility of asthmatic airways. Am Rev Respir Dis 1993;148:806-809. (Pubitemid 23263796)
5. Parameswaran K, Willems-Widyastuti A, Alagappan VK, Radford K, Kranenburg AR, Sharma HS. Role of extracellular matrix and its regulators in human airway smooth muscle biology. Cell Biochem Biophys 2006;44:139-146. (Pubitemid 43099578)
6. Bai TR, Knight DA. Structural changes in the airways in asthma: observations and consequences. Clin Sci (Lond) 2005;108:463-477. (Pubitemid 40827554)
7. Stewart AG, Tomlinson PR, Wilson J. Airway wall remodelling in asthma: a novel target for the development of anti-asthma drugs. Trends Pharmacol Sci 1993;14:275-279. (Pubitemid 23204246)
8. Fay WP, Garg N, Sunkar M. Vascular functions of the plasminogen activation system. Arterioscler Thromb Vasc Biol 2007;27:1231-1237. (Pubitemid 46809410)
9. Hajjar KA, Deora A. New concepts in fibrinolysis and angiogenesis. Curr Atheroscler Rep 2000;2:417-421.
10. Lijnen HR. Elements of the fibrinolytic system. Ann N Y Acad Sci 2001;936:226-236. (Pubitemid 32613910)
11. Khor YH, Teoh AK, Lam SM, Mo DC,Weston S, Reid DW, Walters EH. Increased vascular permeability precedes cellular inflammation as asthma control deteriorates. Clin Exp Allergy 2009;39:1659-1667.
12. Kowal K, Zukowski S, Moniuszko M, Bodzenta-Lukaszyk A. Plasminogen activator inhibitor-1 (PAI-1) and urokinase plasminogen activator (uPA) in sputum of allergic asthma patients. Folia Histochem Cytobiol 2008;46:193-198.
13. Cho SH, Tam SW, Demissie-Sanders S, Filler SA, Oh CK. Production of plasminogen activator inhibitor-1 by human mast cells and its possible role in asthma. J Immunol 2000;165:3154-3161.
14. Wagers S, Lundblad LK, Ekman M, Irvin CG, Bates JH. The allergic mouse model of asthma: normal smooth muscle in an abnormal lung? J Appl Physiol 2004;96:2019-2027. (Pubitemid 38661478)
15. Kuramoto E, Nishiuma T, Kobayashi K, YamamotoM, Kono Y, Funada Y, Kotani Y, Sisson TH, Simon RH, Nishimura Y. Inhalation of urokinasetype plasminogen activator reduces airway remodeling in a murine asthma model. Am J Physiol Lung CellMol Physiol 2009;296:L337-L346.
16. Jarjour NN, Enhorning G. Antigen-induced airway inflammation in atopic subjects generates dysfunction of pulmonary surfactant. Am J Respir Crit Care Med 1999;160:336-341. (Pubitemid 29326109)
17. Ishida T, Tsukada H, Hasegawa T, Yoshizawa H, Gejyo F. Matrix metalloproteinase-1 activation via plasmin generated on alveolar epithelial cell surfaces. Lung 2006;184:15-19.
18. Pins GD, Collins-Pavao ME, Van De Water L, Yarmush ML, Morgan JR. Plasmin triggers rapid contraction and degradation of fibroblast-populated collagen lattices. J Invest Dermatol 2000;114:647-653. (Pubitemid 30226995)
19. Laumonnier Y, Syrovets T, Burysek L, Simmet T. Identification of the annexin A2 heterotetramer as a receptor for the plasmin-induced signaling in human peripheral monocytes. Blood 2006;107:3342-3349.
20. Li Q, Laumonnier Y, Syrovets T, Simmet T. Plasmin triggers cytokine induction in human monocyte-derived macrophages. Arterioscler Thromb Vasc Biol 2007;27:1383-1389. (Pubitemid 46809429)
21. Kim J, Hajjar KA. Annexin II: a plasminogen-plasminogen activator coreceptor. Front Biosci 2002;7:d341-d348.
22. Swaisgood CM, Aronica MA, Swaidani S, Plow EF. Plasminogen is an important regulator in the pathogenesis of a murine model of asthma. Am J Respir Crit Care Med 2007;176:333-342. (Pubitemid 47267466)
23. Begin P, Tremblay K, Daley D, Lemire M, Claveau S, Salesse C, Kacel S, Montpetit A, Becker A, Chan-Yeung M, et al. Association of urokinase-type plasminogen activator with asthma and atopy. Am J Respir Crit Care Med 2007;175:1109-1116. (Pubitemid 46855451)
24. Barton SJ, Koppelman GH, Vonk JM, Browning CA, Nolte IM, Stewart CE, Bainbridge S, Mutch S, Rose-Zerilli MJ, Postma DS, et al. PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline. J Allergy Clin Immunol 2009;123:1391-1400.
25. Cesarman GM, Guevara CA, Hajjar KA. An endothelial cell receptor for plasminogen/tissue plasminogen activator (t-PA). II. Annexin II-mediated enhancement of t-PA-dependent plasminogen activation. J Biol Chem 1994;269:21198-21203.
26. Kwon M, Caplan JF, Filipenko NR, Choi KS, Fitzpatrick SL, Zhang L, Waisman DM. Identification of annexin II heterotetramer as a plasmin reductase. J Biol Chem 2002;277:10903-10911. (Pubitemid 34952845)
27. Schuliga M, Ong SC, Soon L, Zal F, Harris T, Stewart AG. Airway smooth muscle remodels pericellular collagen fibrils: implications for proliferation. Am J Physiol 2010;298:L584-L592.
28. Stewart CE, Sayers I. Characterisation of urokinase plasminogen activator receptor variants in human airway and peripheral cells. BMC Mol Biol 2009;10:75.
29. Horowitz JC, Rogers DS, Simon RH, Sisson TH, Thannickal VJ. Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis. Am J Respir Cell Mol Biol 2008;38:78-87.
30. Fernandes D, Guida E, Koutsoubos V, Harris T, Vadiveloo P, Wilson JW, Stewart AG. Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. Am J Respir Cell Mol Biol 1999;21:77-88. (Pubitemid 129508630)
31. Chandrakasan G, Torchia DA, Piez KA. Preparation of intact monomeric collagen from rat tail tendon and skin and the structure of the nonhelical ends in solution. J Biol Chem 1976;251:6062-6067.
32. Schuliga MJ, See I, Ong SC, Soon L, Camoretti-Mercado B, Harris T, Stewart AG. Fibrillar collagen clamps lung mesenchymal cells in a nonproliferative and noncontractile phenotype. Am J Respir Cell Mol Biol 2009;41:731-741.
33. Diaz VM, Hurtado M, Thomson TM, Reventos J, Paciucci R. Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro. Gut 2004;53:993-1000. (Pubitemid 38824158)
34. Bok RA, Hansell EJ, Nguyen TP, Greenberg NM, McKerrow JH, Shuman MA. Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model. Prostate Cancer Prostatic Dis 2003;6:272-280. (Pubitemid 38088188)
35. Kucharewicz I, Kowal K, Buczko W, Bodzenta-Lukaszyk A. The plasmin system in airway remodeling. Thromb Res 2003;112:1-7. (Pubitemid 38167577)
36. Levin EG, Loskutoff DJ. Comparative studies of the fibrinolytic activity of cultured vascular cells. Thromb Res 1979;15:869-878. (Pubitemid 10237151)
37. Rossignol P, Angles-Cano E, Lijnen HR. Plasminogen activator inhibitor-1 impairs plasminogen activation-mediated vascular smooth muscle cell apoptosis. Thromb Haemost 2006;96:665-670. (Pubitemid 44782548)
38. Nicholl SM, Roztocil E, Galaria II, Davies MG. Plasmin induces smooth muscle cell proliferation. J Surg Res 2005;127:39-45. (Pubitemid 40814628)
39. Chu EK, Cheng J, Foley JS, Mecham BH, Owen CA, Haley KJ, Mariani TJ, Kohane IS, Tschumperlin DJ, Drazen JM. Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells. Am J Respir Cell Mol Biol 2006;35:628-638. (Pubitemid 44901852)
40. Coutts A, Chen G, Stephens N, Hirst S, Douglas D, Eichholtz T, Khalil N. Release of biologically active TGF-beta from airway smooth muscle cells induces autocrine synthesis of collagen. Am J Physiol 2001;280:L999-L1008.
41. Zhang L, Seiffert D, Fowler BJ, Jenkins GR, Thinnes TC, Loskutoff DJ, Parmer RJ, Miles LA. Plasminogen has a broad extrahepatic distribution. Thromb Haemost 2002;87:493-501. (Pubitemid 34232492)
42. Cederholm-Williams SA. Concentration of plasminogen and antiplasmin in plasma and serum. J Clin Pathol 1981;34:979-981. (Pubitemid 11062203)
43. Clowes AW, Clowes MM, Au YP, Reidy MA, Belin D. Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery. Circ Res 1990;67:61-67. (Pubitemid 20223727)
44. Araujo BB, Dolhnikoff M, Silva LF, Elliot J, Lindeman JH, Ferreira DS, Mulder A, Gomes HA, Fernezlian SM, James A, et al. Extracellular matrix components and regulators within the airway smooth muscle in asthma. Eur Respir J 2008;32:61-69.
45. Henderson N, Markwick LJ, Elshaw SR, Freyer AM, Knox AJ, Johnson SR. Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration. Am J Physiol 2007;292:L1030-L1038. (Pubitemid 46608250)
46. Oh CK, Ariue B, Alban RF, Shaw B, Cho SH. PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model. Biochem Biophys Res Commun 2002;294:1155-1160. (Pubitemid 34687171)
47. Perumal S, Antipova O, Orgel JP. Collagen fibril architecture, domain organization, and triple-helical conformation govern its proteolysis. Proc Natl Acad Sci USA 2008;105:2824-2829. (Pubitemid 351723628)
48. Burgess JK, Ceresa C, Johnson SR, Kanabar V, Moir LM, Nguyen TT, Oliver BG, Schuliga M, Ward J. Tissue and matrix influences on airway smooth muscle function. Pulm Pharmacol Ther 2009;22:379-387.
49. Bourke JE, Li X, Foster SR,Wee E, Dagher H, Ziogas J, Harris T, Bonacci JV, Stewart AG. Collagen remodelling by airway smooth muscle is resistant to steroids and fbetag2-agonists. Eur Respir J 2010 Jul 1 [Epub ahead of print].
50. Wang N, Planus E, Pouchelet M, Fredberg JJ, Barlovatz-Meimon G. Urokinase receptor mediates mechanical force transfer across the cell surface. Am J Physiol 1995;268:C1062-C1066.
51. Carlin SM, Resink TJ, Tamm M, Roth M. Urokinase signal transduction and its role in cell migration. FASEB J 2005;19:195-202. (Pubitemid 40189260)
52. Fixman ED, Stewart A, Martin JG. Basic mechanisms of development of airway structural changes in asthma. Eur Respir J 2007;29:379-389. (Pubitemid 46231919)
53. Ivaska J, Reunanen H, Westermarck J, Koivisto L, Kahari VM, Heino J. Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail. J Cell Biol 1999;147:401-416.
54. Koyama H, Raines EW, Bornfeldt KE, Roberts JM, Ross R. Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of CDK2 inhibitors. Cell 1996;87:1069-1078. (Pubitemid 26427990)
55. Hornebeck W, Maquart FX. Proteolyzed matrix as a template for the regulation of tumor progression. Biomed Pharmacother 2003;57:223-230. (Pubitemid 36903199)
56. Holgate ST, Holloway J, Wilson S, Bucchieri F, Puddicombe S, Davies DE. Epithelial-mesenchymal communication in the pathogenesis of chronic asthma. Proc Am Thorac Soc 2004;1:93-98.
57. Pampuch A, Kowal K, Bodzenta-Lukaszyk A, Di Castelnuovo A, Chyczewski L, Donati MB, Iacoviello L. The 2675 4G/5G plasminogen activator inhibitor-1 promoter polymorphism in house dust mite-sensitive allergic asthma patients. Allergy 2006;61:234-238. (Pubitemid 43381836)
58. Cervella P, Silengo L, Pastore C, Altruda F. Human beta 1-integrin gene expression is regulated by two promoter regions. J Biol Chem 1993;268:5148-5155. (Pubitemid 23081642)
59. Huang SS, Huang JS. TGF-beta control of cell proliferation. J Cell Biochem 2005;96:447-462.
60. Stewart CE, Hall IP, Parker SG, Moffat MF, Wardlaw AJ, Connolly MJ, Ruse C, Sayers I. PLAUR polymorphisms and lung function in UK smokers. BMC Med Genet 2009;10:112.
61. Huang CM, Chen CL, Tsai JJ, Tsai CH, Tsai FJ. Association between urokinase gene 39-UTR T/C polymorphism and Chinese patients with rheumatoid arthritis in Taiwan. Clin Exp Rheumatol 2004;22:219-222. (Pubitemid 38444812)