TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1

Human Molecular Genetics

Volumn 23, Issue 19, 2014, Pages 5036-5051

  He, Fang ^a   Krans, Amy ^a   Freibaum, Brian D ^b   Paul Taylor, J ^b   Todd, Peter K ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUSED IN SARCOMA PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2 B1; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 6; MESSENGER RNA; RAN PROTEIN; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; EPHRIN RECEPTOR; PROTEIN BINDING; PROTEIN TDP-43; TBPH PROTEIN, DROSOPHILA;

5' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CGG REPEAT; CONTROLLED STUDY; CYTOPLASM; DEGENERATIVE DISEASE; FRAGILE X ASSOCIATED TREMOR ATAXIA SYNDROME; FRUIT FLY MODEL; GENE STRUCTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; NEUROTOXICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA BINDING; RNA INTERFERENCE; ANIMAL; ATAXIA; CELL LINE; CHEMISTRY; DROSOPHILA; EYE; FRAGILE X SYNDROME; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PROTEIN DOMAIN; PROTEIN SYNTHESIS; TRANSGENIC ANIMAL; TREMOR; TRINUCLEOTIDE REPEAT;

ANIMALIA;

ALTERNATIVE SPLICING; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ATAXIA; CELL LINE; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EYE; FRAGILE X SYNDROME; GENE EXPRESSION; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HUMANS; MUTATION; NEURODEGENERATIVE DISEASES; PHENOTYPE; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECEPTORS, EPH FAMILY; TRANSCRIPTION, GENETIC; TREMOR; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84908323798     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu216     Document Type: Article

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