CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome

Neuron

Volumn 78, Issue 3, 2013, Pages 440-455

  Todd, Peter K ^a   Oh, SeokYoon ^a   Krans, Amy ^a   He, Fang ^a   Sellier, Chantal ^c,d   Frazer, Michelle ^a   Renoux, Abigail J ^a,b   Chen, Kai chun ^a   Scaglione, K Matthew ^a   Basrur, Venkatesha ^a   Elenitoba Johnson, Kojo ^a   Vonsattel, Jean P ^e   Louis, Elan D ^e   Sutton, Michael A ^b   Taylor, J Paul ^f   Mills, Ryan E ^b   Charlet Berguerand, Nicholas ^c   Paulson, Henry L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d sous section pédiatrie   (France)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FMRPOLYG PROTEIN; FRAGILE X MENTAL RETARDATION PROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA; CELL NUCLEUS INCLUSION BODY; CEREBELLUM; CGG REPEAT; CONTROLLED STUDY; DNA STRUCTURE; DROSOPHILA; FRAGILE X ASSOCIATED TREMOR ATAXIA SYNDROME; FRAGILE X SYNDROME; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; HUMAN CELL; MOUSE; NERVE DEGENERATION; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; RAN TRANSLATION; RIBOSOME; RNA TRANSLATION; TRANSLATION INITIATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ATAXIA; BRAIN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DROSOPHILA; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; HUMANS; NERVE DEGENERATION; NEURONS; PROTEIN BIOSYNTHESIS; TREMOR; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84877331220     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2013.03.026     Document Type: Article

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