Loss of TDP-43 causes age-dependent progressive motor neuron degeneration

Brain

Volumn 136, Issue 5, 2013, Pages 1371-1382

  Iguchi, Yohei ^a   Katsuno, Masahisa ^a   Niwa, Jun Ichi ^b   Takagi, Shinnosuke ^a   Ishigaki, Shinsuke ^a   Ikenaka, Kensuke ^a   Kawai, Kaori ^a   Watanabe, Hirohisa ^a   Yamanaka, Koji ^c,d   Takahashi, Ryosuke ^e   Misawa, Hidemi ^f   Sasaki, Shoichi ^g   Tanaka, Fumiaki ^a,h   Sobue, Gen ^a,d  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b AICHI MEDICAL UNIVERSITY   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f KEIO UNIVERSITY   (Japan)

^g TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^h YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

amyotrophic lateral sclerosis; autophagosome; axonal degeneration; transactive response DNA binding protein 43

Indexed keywords

TAR DNA BINDING PROTEIN;

AGING; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; CONTROLLED STUDY; CRANIAL NERVE; DISEASE COURSE; ELECTRON MICROSCOPY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; MUSCLE ATROPHY; MUSCLE DENERVATION; NERVE DEGENERATION; NEUROLOGIC EXAMINATION; NEUROMUSCULAR SYNAPSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; ROTAROD TEST; SKELETAL MUSCLE; WEIGHT REDUCTION;

EID: 84877292537     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt029     Document Type: Article

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