The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures

Journal of Biological Chemistry

Volumn 288, Issue 14, 2013, Pages 9860-9866

  Reddy, Kaalak ^a,b   Zamiri, Bita ^b   Stanley, Sabrina Y R ^b   Macgregor, Robert B ^b   Pearson, Christopher E ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DISEASE CONTROL; DNA SEQUENCES; NEURODEGENERATIVE DISEASES; OLIGONUCLEOTIDES; PROTEINS;

AMYOTROPHIC LATERAL SCLEROSIS; FRONTOTEMPORAL DEMENTIAS; G-QUADRUPLEX STRUCTURE; G-QUADRUPLEXES; GENETIC INSTABILITY; PROMOTER ACTIVITIES; QUADRUPLEX FORMATION; RNA SEQUENCES; SPLICING FACTORS; UNIMOLECULAR;

RNA;

PROTEIN MBNL1; SELF SPLICING RIBOSOMAL RNA; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; C9ORF72 GENE; CONTROLLED STUDY; FRONTOTEMPORAL DEMENTIA; G QUADRUPLEX STRUCTURE; GENE; GENE ACTIVITY; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; LONG TERMINAL REPEAT; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN RNA BINDING; RNA SEQUENCE; RNA STABILITY; RNA STRUCTURE; RNA TRANSCRIPTION; RNA TRANSLATION;

EID: 84875981640     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C113.452532     Document Type: Article

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