Isolation and characterization of Dek, a Drosophila Eph receptor protein tyrosine kinase

Molecular and Cellular Neurosciences

Volumn 13, Issue 5, 1999, Pages 337-347

  Scully, Audra L ^a   McKeown, Mike ^a   Thomas, John B ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR;

ARTICLE; DROSOPHILA; ENZYME ANALYSIS; ENZYME ISOLATION; IMMUNOHISTOCHEMISTRY; INTERNEURON; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

EID: 0032993165     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1999.0752     Document Type: Article

References (49)

1. Ashburner M. Drosophila: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
2. Bourgouin C., Lundgren S. E., Thomas J. B. apterous is a Drosophila LIM domain gene required for the development of a subset of embryonic muscles. Neuron. 9:1992;549-561.
3. Brand A. H., Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:1993;401-415.
4. Brown N. H., Kafatos F. C. Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203:1988;425-437.
5. Brückner K., Klein R. Signaling by Eph receptors and their ephrin ligands. Curr. Opin. Neurobiol. 8:1998;375-382.
6. Callahan C. A., Thomas J. B. Tau-beta-galactosidase, an axon-targeted fusion protein. Proc. Natl. Acad. Sci. USA. 91:1994;5972-5976.
7. Cavener D. R. Comparison of consensus flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res. 15:1987;1353-1361.
8. Chen J., Nachabah A., Scherer C., Ganju P., Reith A., Bronson R., Ruley H. E. Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion. Oncogene. 12:1996;979-988.
9. Dottori M., Hartley L., Galea M., Paxinos G., Polizzotto M., Kilpatrick T., Bartlett P. F., Murphy M., Kontgen F., Boyd A. W. EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. Proc. Natl. Acad. Sci. USA. 95:1998;13248-13253.
10. Doyle D. A., Lee A., Lewis J., Kim E., Sheng M., MacKinnon R. Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ. Cell. 85:1996;1067-1076.
11. Drescher U. The Eph family in the patterning of neural development. Curr. Biol. 7:1997;R799-807.
12. Drescher U., Bonhoeffer F., Muller B. K. The Eph family in retinal axon guidance. Curr. Opin. Neurobiol. 7:1997;75-80.
13. Ellis C., Kasmi F., Ganju P., Walls E., Panayotou G., Reith A. D. A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn. Oncogene. 12:1996;1727-1736.
14. Evan G. I., Lewis G. K., Ramsay G., Bishop J. M. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5:1985;3610-3616.
15. George S. E., Simokat K., Hardin J., Chisholm A. D. The VAB-1 Eph receptor tyrosine kinase functions in neural and epithelial morphogenesis in C. elegans. Cell. 92:1998;633-643.
16. Giebel L. B., Spritz R. A. Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism. Proc. Natl. Acad. Sci. USA. 88:1991;8696-8699.
17. Hay B. A., Wolff T., Rubin G. M. Expression of baculovirus p35 prevents cell death in Drosophila. Development. 120:1994;2121-2129.
18. Henkemeyer M., Orioli D., Henderson J. T., Saxton T. M., Roder J., Pawson T., Klein R. Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell. 86:1996;35-46.
19. Hock B., Böhme B., Karn T., Yamamoto T., Kaibuchi K., Holtrich U., Holland S., Pawson T., Rübsamen-Waigmann H., Strebhardt K. PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor. Proc. Natl. Acad. Sci. USA. 95:1998;9779-9784.
20. Holland S. J., Gale N. W., Gish G. D., Roth R. A., Songyang Z., Cantley L. C., Henkemeyer M., Yancopoulos G. D., Pawson T. Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells. EMBO J. 16:1997;3877-3888.
21. Holland S. J., Peles E., Pawson T., Schlessinger J. Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta. Curr. Opin. Neurobiol. 8:1998;117-127.
22. Klaes A., Menne T., Stollewerk A., Scholz H., Klambt C. The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS. Cell. 78:1994;149-160.
23. Lai C., Lemke G. An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron. 6:1991;691-704.
24. Lin D. M., Goodman C. S. Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance. Neuron. 13:1994;507-523.
25. Luo L., Liao Y. J., Jan L. Y., Jan Y. N. Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes Dev. 8:1994;1787-1802.
26. Moller D. E., Flier J. S. Insulin resistance - Mechanisms, syndromes, and implications [see comments]. N. Engl. J. Med. 325:1991;938-948.
27. Orioli D., Henkemeyer M., Lemke G., Klein R., Pawson T. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 15:1996;6035-6049.
28. Park S., Frisen J., Barbacid M. Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors. EMBO J. 16:1997;3106-3114.
29. Ponting C. P. SAM: A novel motif in yeast sterile and Drosophila polyhomeotic proteins. Protein Sci. 4:1995;1928-1930.
30. Rubin G. M., Spradling A. C. Genetic transformation of Drosophila with transposable element vectors. Science. 218:1982;348-353.
31. Ruvkun G., Hobert O. The taxonomy of developmental control in Caenorhabditis elegans. Science. 282:1998;2033-2041.
32. Schultz J., Ponting C. P., Hofmann K., Bork P. SAM as a protein interaction domain involved in developmental regulation. Protein Sci. 6:1997;249-253.
33. Sheng M. PDZs and receptor/channel clustering: Rounding up the latest suspects. Neuron. 17:1996;575-578.
34. Songyang Z., Fanning A. S., Fu C., Xu J., Marfatia S. M., Chishti A. H., Crompton A., Chan A. C., Anderson J. M., Cantley L. C. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science. 275:1997;73-77.
35. Stein E., Cerretti D. P., Daniel T. O. Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells. J. Biol. Chem. 271:1996;23588-23593.
36. Stein E., Huynh-Do U., Lane A. A., Cerretti D. P., Daniel T. O. Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase. J. Biol. Chem. 273:1998a;1303-1308.
37. Stein E., Lane A. A., Cerretti D. P., Schoecklmann H. O., Schroff A. D., Van Etten R. L., Daniel T. O. Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses. Genes Dev. 12:1998b;667-678.
38. Tamkun J. W., Deuring R., Scott M. P., Kissinger M., Pattatucci A. M., Kaufman T. C., Kennison J. A. brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell. 68:1992;561-572.
39. Tan J. C., Nocka K., Ray P., Traktman P., Besmer P. The dominant W42 spotting phenotype results from a missense mutation in the c-kit receptor kinase. Science. 247:1990;209-212.
40. Thomas J. B., Bastiani M. J., Bate C. M., Goodman C. S. From grasshopper to Drosophila: A common plan for neuronal development. Nature. 310:1984;203-207.
41. Thor S., Andersson S. G., Tomlinson A., Thomas J. B. A LIM-homeodomain combinatorial code for motor-neuron pathway selection. Nature. 397:1999;76-80.
42. Thor S., Thomas J. B. The Drosophila islet gene governs axon pathfinding and neurotransmitter identity. Neuron. 18:1997;397-409.
43. Tsunoda S., Sierralta J., Sun Y., Bodner R., Suzuki E., Becker A., Socolich M., Zuker C. S. A multivalent PDZ-domain protein assembles signaling complexes in a G-protein-coupled cascade. Nature. 388:1997;243-249.
44. Turner D. L., Weintraub H. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev. 8:1994;1434-1447.
45. Vaillancourt R. R., Gardner A. M., Kazlauskas A., Johnson G. L. The kinase-inactive PDGF beta-receptor mediates activation of the MAP kinase cascade via the endogenous PDGF alpha-receptor in HepG2 cells. Oncogene. 13:1996;151-159.
46. van der Geer P., Hunter T., Lindberg R. A. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 10:1994;251-337.
47. Van Vactor D., Sink H., Fambrough D., Tsoo R., Goodman C. S. Genes that control neuromuscular specificity in Drosophila. Cell. 73:1993;1155-1164.
48. Wallrath L. L., Elgin S. C. Position effect variegation in Drosophila is associated with an altered chromatin structure. Genes Dev. 9:1995;1263-1277.
49. Zisch A. H., Kalo M. S., Chong L. D., Pasquale E. B. Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region. Oncogene. 16:1998;2657-2670.