Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS)

Journal of Biological Chemistry

Volumn 285, Issue 15, 2010, Pages 11068-11072

  Hanson, Keith A ^a   Kim, Sang Hwa ^a   Wassarman, David A ^a   Tibbetts, Randal S ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; AUTOPHAGY; CO-EXPRESSION; CYTOSOLIC; DNA-BINDING PROTEIN; DOSE-DEPENDENT; DROSOPHILA MELANOGASTER; LIFE SPAN; MOTOR NEURONS; NEUROTOXICITY; NUCLEAR FUNCTION; PROTEASOMES; UBIQUILIN; UBIQUITIN; WILD TYPES;

BRAIN; NEURONS;

PROTEINS;

BINDING PROTEIN; PROTEASOME; TAR DNA BINDING PROTEIN; UBIQUILIN 1; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CYTOSOL; DISEASE SEVERITY; DROSOPHILA MELANOGASTER; LIFESPAN; MICROSCOPY; MOTONEURON; MOTOR DYSFUNCTION; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SURVIVAL;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CELL NUCLEUS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; HUMANS; MODELS, BIOLOGICAL; MOTOR NEURONS; NEURONS; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; TIME FACTORS; TRANSGENES; UBIQUITIN;

DROSOPHILA MELANOGASTER;

EID: 77951236534     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C109.078527     Document Type: Article

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