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Volumn 1830, Issue 2, 2013, Pages 2297-2306

On the role of Wnt/β-catenin signaling in stem cells

Author keywords

Embryonic stem cells; Intestinal stem cells; Wnt signaling

Indexed keywords

BETA CATENIN; DICKKOPF 1 PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR 7 LIKE 1; WNT PROTEIN;

EID: 84872498040     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.08.010     Document Type: Review
Times cited : (85)

References (123)
  • 1
    • 84862207240 scopus 로고    scopus 로고
    • Three decades of Wnts: A personal perspective on how a scientific field developed
    • R. Nusse, and H. Varmus Three decades of Wnts: a personal perspective on how a scientific field developed EMBO J. 31 2012 2670 2684
    • (2012) EMBO J. , vol.31 , pp. 2670-2684
    • Nusse, R.1    Varmus, H.2
  • 4
    • 33947213491 scopus 로고    scopus 로고
    • Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling
    • M. Kurayoshi, H. Yamamoto, S. Izumi, and A. Kikuchi Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling Biochem. J. 402 2007 515 523
    • (2007) Biochem. J. , vol.402 , pp. 515-523
    • Kurayoshi, M.1    Yamamoto, H.2    Izumi, S.3    Kikuchi, A.4
  • 5
    • 0024972122 scopus 로고
    • A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
    • C.R. Vinson, S. Conover, and P.N. Adler A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains Nature 338 1989 263 264
    • (1989) Nature , vol.338 , pp. 263-264
    • Vinson, C.R.1    Conover, S.2    Adler, P.N.3
  • 8
    • 54249096215 scopus 로고    scopus 로고
    • Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase
    • Y. Liu, B. Rubin, P.V. Bodine, and J. Billiard Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase J. Cell. Biochem. 105 2008 497 502
    • (2008) J. Cell. Biochem. , vol.105 , pp. 497-502
    • Liu, Y.1    Rubin, B.2    Bodine, P.V.3    Billiard, J.4
  • 9
    • 0037431230 scopus 로고    scopus 로고
    • Wnt-mediated axon guidance via the Drosophila derailed receptor
    • S. Yoshikawa, R.D. McKinnon, M. Kokel, and J.B. Thomas Wnt-mediated axon guidance via the Drosophila derailed receptor Nature 422 2003 583 588
    • (2003) Nature , vol.422 , pp. 583-588
    • Yoshikawa, S.1    McKinnon, R.D.2    Kokel, M.3    Thomas, J.B.4
  • 10
    • 78650150896 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. LXXX. The class Frizzled receptors
    • G. Schulte International Union of Basic and Clinical Pharmacology. LXXX. The class Frizzled receptors Pharmacol. Rev. 62 2010 632 667
    • (2010) Pharmacol. Rev. , vol.62 , pp. 632-667
    • Schulte, G.1
  • 11
    • 39749147015 scopus 로고    scopus 로고
    • From individual Wnt pathways towards a Wnt signalling network
    • H.A. Kestler, and M. Kuhl From individual Wnt pathways towards a Wnt signalling network Philos. Trans. R. Soc. Lond. B Biol. Sci. 363 2008 1333 1347
    • (2008) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.363 , pp. 1333-1347
    • Kestler, H.A.1    Kuhl, M.2
  • 12
    • 4243067196 scopus 로고    scopus 로고
    • The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
    • E. Lee, A. Salic, R. Kruger, R. Heinrich, and M.W. Kirschner The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway PLoS Biol. 1 2003 E10
    • (2003) PLoS Biol. , vol.1 , pp. 10
    • Lee, E.1    Salic, A.2    Kruger, R.3    Heinrich, R.4    Kirschner, M.W.5
  • 14
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • C. Liu, Y. Li, M. Semenov, C. Han, G.H. Baeg, Y. Tan, Z. Zhang, X. Lin, and X. He Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism Cell 108 2002 837 847
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.H.5    Tan, Y.6    Zhang, Z.7    Lin, X.8    He, X.9
  • 17
    • 69249147832 scopus 로고    scopus 로고
    • Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl
    • Y. Qin, L. Li, W. Pan, and D. Wu Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl J. Biol. Chem. 284 2009 22544 22548
    • (2009) J. Biol. Chem. , vol.284 , pp. 22544-22548
    • Qin, Y.1    Li, L.2    Pan, W.3    Wu, D.4
  • 19
    • 78751559473 scopus 로고    scopus 로고
    • Wnt signalling: The case of the 'missing' G-protein
    • C.C. Malbon Wnt signalling: the case of the 'missing' G-protein Biochem. J. 433 2011 e3 e5
    • (2011) Biochem. J. , vol.433
    • Malbon, C.C.1
  • 20
    • 78751483422 scopus 로고    scopus 로고
    • Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins
    • A. Koval, and V.L. Katanaev Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins Biochem. J. 433 2011 435 440
    • (2011) Biochem. J. , vol.433 , pp. 435-440
    • Koval, A.1    Katanaev, V.L.2
  • 21
    • 33645837037 scopus 로고    scopus 로고
    • Kinases and G proteins join the Wnt receptor complex
    • T. Quaiser, R. Anton, and M. Kuhl Kinases and G proteins join the Wnt receptor complex Bioessays 28 2006 339 343
    • (2006) Bioessays , vol.28 , pp. 339-343
    • Quaiser, T.1    Anton, R.2    Kuhl, M.3
  • 22
    • 33749535905 scopus 로고    scopus 로고
    • Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery
    • S. Angers, T. Li, X. Yi, M.J. MacCoss, R.T. Moon, and N. Zheng Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery Nature 443 2006 590 593
    • (2006) Nature , vol.443 , pp. 590-593
    • Angers, S.1    Li, T.2    Yi, X.3    MacCoss, M.J.4    Moon, R.T.5    Zheng, N.6
  • 24
    • 77951233751 scopus 로고    scopus 로고
    • Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets
    • A. Weise, K. Bruser, S. Elfert, B. Wallmen, Y. Wittel, S. Wohrle, and A. Hecht Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets Nucleic Acids Res. 38 2010 1964 1981
    • (2010) Nucleic Acids Res. , vol.38 , pp. 1964-1981
    • Weise, A.1    Bruser, K.2    Elfert, S.3    Wallmen, B.4    Wittel, Y.5    Wohrle, S.6    Hecht, A.7
  • 25
    • 34247589181 scopus 로고    scopus 로고
    • Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway
    • A. Schambony, and D. Wedlich Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway Dev. Cell 12 2007 779 792
    • (2007) Dev. Cell , vol.12 , pp. 779-792
    • Schambony, A.1    Wedlich, D.2
  • 27
    • 0034214847 scopus 로고    scopus 로고
    • The Wnt/Ca2 + pathway: A new vertebrate Wnt signaling pathway takes shape
    • M. Kuhl, L.C. Sheldahl, M. Park, J.R. Miller, and R.T. Moon The Wnt/Ca2 + pathway: a new vertebrate Wnt signaling pathway takes shape Trends Genet. 16 2000 279 283
    • (2000) Trends Genet. , vol.16 , pp. 279-283
    • Kuhl, M.1    Sheldahl, L.C.2    Park, M.3    Miller, J.R.4    Moon, R.T.5
  • 28
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
    • X. Wu, X. Tu, K.S. Joeng, M.J. Hilton, D.A. Williams, and F. Long Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling Cell 133 2008 340 353
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5    Long, F.6
  • 29
    • 0034920494 scopus 로고    scopus 로고
    • Antagonistic regulation of convergent extension movements in Xenopus by Wnt/beta-catenin and Wnt/Ca2 + signaling
    • M. Kuhl, K. Geis, L.C. Sheldahl, T. Pukrop, R.T. Moon, and D. Wedlich Antagonistic regulation of convergent extension movements in Xenopus by Wnt/beta-catenin and Wnt/Ca2 + signaling Mech. Dev. 106 2001 61 76
    • (2001) Mech. Dev. , vol.106 , pp. 61-76
    • Kuhl, M.1    Geis, K.2    Sheldahl, L.C.3    Pukrop, T.4    Moon, R.T.5    Wedlich, D.6
  • 31
    • 61449249121 scopus 로고    scopus 로고
    • Selective activation mechanisms of Wnt signaling pathways
    • A. Kikuchi, H. Yamamoto, and A. Sato Selective activation mechanisms of Wnt signaling pathways Trends Cell Biol. 19 2009 119 129
    • (2009) Trends Cell Biol. , vol.19 , pp. 119-129
    • Kikuchi, A.1    Yamamoto, H.2    Sato, A.3
  • 32
    • 2942592798 scopus 로고    scopus 로고
    • Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase
    • S. Kishida, H. Yamamoto, and A. Kikuchi Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase Mol. Cell. Biol. 24 2004 4487 4501
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4487-4501
    • Kishida, S.1    Yamamoto, H.2    Kikuchi, A.3
  • 33
    • 0030941498 scopus 로고    scopus 로고
    • A member of the Frizzled protein family mediating axis induction by Wnt-5A
    • X. He, J.P. Saint-Jeannet, Y. Wang, J. Nathans, I. Dawid, and H. Varmus A member of the Frizzled protein family mediating axis induction by Wnt-5A Science 275 1997 1652 1654
    • (1997) Science , vol.275 , pp. 1652-1654
    • He, X.1    Saint-Jeannet, J.P.2    Wang, Y.3    Nathans, J.4    Dawid, I.5    Varmus, H.6
  • 34
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
    • A.J. Mikels, and R. Nusse Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context PLoS Biol. 4 2006 e115
    • (2006) PLoS Biol. , vol.4 , pp. 115
    • Mikels, A.J.1    Nusse, R.2
  • 35
    • 0038497887 scopus 로고    scopus 로고
    • Frizzled receptor dimerization is sufficient to activate the Wnt/beta-catenin pathway
    • C. Carron, A. Pascal, A. Djiane, J.C. Boucaut, D.L. Shi, and M. Umbhauer Frizzled receptor dimerization is sufficient to activate the Wnt/beta-catenin pathway J. Cell Sci. 116 2003 2541 2550
    • (2003) J. Cell Sci. , vol.116 , pp. 2541-2550
    • Carron, C.1    Pascal, A.2    Djiane, A.3    Boucaut, J.C.4    Shi, D.L.5    Umbhauer, M.6
  • 40
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • A. Glinka, W. Wu, H. Delius, A.P. Monaghan, C. Blumenstock, and C. Niehrs Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction Nature 391 1998 357 362
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1    Wu, W.2    Delius, H.3    Monaghan, A.P.4    Blumenstock, C.5    Niehrs, C.6
  • 41
    • 66049117813 scopus 로고    scopus 로고
    • Naive and primed pluripotent states
    • J. Nichols, and A. Smith Naive and primed pluripotent states Cell Stem Cell 4 2009 487 492
    • (2009) Cell Stem Cell , vol.4 , pp. 487-492
    • Nichols, J.1    Smith, A.2
  • 42
    • 69649084228 scopus 로고    scopus 로고
    • The transcriptional foundation of pluripotency
    • I. Chambers, and S.R. Tomlinson The transcriptional foundation of pluripotency Development 136 2009 2311 2322
    • (2009) Development , vol.136 , pp. 2311-2322
    • Chambers, I.1    Tomlinson, S.R.2
  • 43
    • 79958263080 scopus 로고    scopus 로고
    • Pluripotency factors in embryonic stem cells regulate differentiation into germ layers
    • M. Thomson, S.J. Liu, L.N. Zou, Z. Smith, A. Meissner, and S. Ramanathan Pluripotency factors in embryonic stem cells regulate differentiation into germ layers Cell 145 2011 875 889
    • (2011) Cell , vol.145 , pp. 875-889
    • Thomson, M.1    Liu, S.J.2    Zou, L.N.3    Smith, Z.4    Meissner, A.5    Ramanathan, S.6
  • 44
    • 69249153489 scopus 로고    scopus 로고
    • Smad, PI3K/Akt, and Wnt-dependent signaling pathways are involved in BMP-4-induced ESC self-renewal
    • M.Y. Lee, H.W. Lim, S.H. Lee, and H.J. Han Smad, PI3K/Akt, and Wnt-dependent signaling pathways are involved in BMP-4-induced ESC self-renewal Stem Cells 27 2009 1858 1868
    • (2009) Stem Cells , vol.27 , pp. 1858-1868
    • Lee, M.Y.1    Lim, H.W.2    Lee, S.H.3    Han, H.J.4
  • 45
    • 53349091628 scopus 로고    scopus 로고
    • Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling
    • T. Sumi, N. Tsuneyoshi, N. Nakatsuji, and H. Suemori Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling Development 135 2008 2969 2979
    • (2008) Development , vol.135 , pp. 2969-2979
    • Sumi, T.1    Tsuneyoshi, N.2    Nakatsuji, N.3    Suemori, H.4
  • 46
    • 39649111114 scopus 로고    scopus 로고
    • Intracellular signaling pathways regulating pluripotency of embryonic stem cells
    • K. Okita, and S. Yamanaka Intracellular signaling pathways regulating pluripotency of embryonic stem cells Curr. Stem Cell Res. Ther. 1 2006 103 111
    • (2006) Curr. Stem Cell Res. Ther. , vol.1 , pp. 103-111
    • Okita, K.1    Yamanaka, S.2
  • 47
    • 77956540297 scopus 로고    scopus 로고
    • FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3beta signaling
    • V.M. Ding, L. Ling, S. Natarajan, M.G. Yap, S.M. Cool, and A.B. Choo FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3beta signaling J. Cell. Physiol. 225 2010 417 428
    • (2010) J. Cell. Physiol. , vol.225 , pp. 417-428
    • Ding, V.M.1    Ling, L.2    Natarajan, S.3    Yap, M.G.4    Cool, S.M.5    Choo, A.B.6
  • 48
    • 53049092465 scopus 로고    scopus 로고
    • Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states
    • K. Hayashi, S.M. Lopes, F. Tang, and M.A. Surani Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states Cell Stem Cell 3 2008 391 401
    • (2008) Cell Stem Cell , vol.3 , pp. 391-401
    • Hayashi, K.1    Lopes, S.M.2    Tang, F.3    Surani, M.A.4
  • 50
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • N. Sato, L. Meijer, L. Skaltsounis, P. Greengard, and A.H. Brivanlou Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor Nat. Med. 10 2004 55 63
    • (2004) Nat. Med. , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 51
    • 33750442483 scopus 로고    scopus 로고
    • Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm
    • R.C. Lindsley, J.G. Gill, M. Kyba, T.L. Murphy, and K.M. Murphy Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm Development 133 2006 3787 3796
    • (2006) Development , vol.133 , pp. 3787-3796
    • Lindsley, R.C.1    Gill, J.G.2    Kyba, M.3    Murphy, T.L.4    Murphy, K.M.5
  • 52
    • 35748984680 scopus 로고    scopus 로고
    • Generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustained Wnt pathway activation
    • M.M. Bakre, A. Hoi, J.C. Mong, Y.Y. Koh, K.Y. Wong, and L.W. Stanton Generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustained Wnt pathway activation J. Biol. Chem. 282 2007 31703 31712
    • (2007) J. Biol. Chem. , vol.282 , pp. 31703-31712
    • Bakre, M.M.1    Hoi, A.2    Mong, J.C.3    Koh, Y.Y.4    Wong, K.Y.5    Stanton, L.W.6
  • 54
    • 77956195155 scopus 로고    scopus 로고
    • Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos
    • M. Gertsenstein, L.M. Nutter, T. Reid, M. Pereira, W.L. Stanford, J. Rossant, and A. Nagy Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos PLoS One 5 2010 e11260
    • (2010) PLoS One , vol.5 , pp. 11260
    • Gertsenstein, M.1    Nutter, L.M.2    Reid, T.3    Pereira, M.4    Stanford, W.L.5    Rossant, J.6    Nagy, A.7
  • 55
    • 77952031756 scopus 로고    scopus 로고
    • Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability
    • H. Kiyonari, M. Kaneko, S. Abe, and S. Aizawa Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability Genesis 48 2010 317 327
    • (2010) Genesis , vol.48 , pp. 317-327
    • Kiyonari, H.1    Kaneko, M.2    Abe, S.3    Aizawa, S.4
  • 56
    • 70349177792 scopus 로고    scopus 로고
    • Stable generation of serum- and feeder-free embryonic stem cell-derived mice with full germline-competency by using a GSK3 specific inhibitor
    • H. Sato, K. Amagai, R. Shimizukawa, and Y. Tamai Stable generation of serum- and feeder-free embryonic stem cell-derived mice with full germline-competency by using a GSK3 specific inhibitor Genesis 47 2009 414 422
    • (2009) Genesis , vol.47 , pp. 414-422
    • Sato, H.1    Amagai, K.2    Shimizukawa, R.3    Tamai, Y.4
  • 58
    • 58049192815 scopus 로고    scopus 로고
    • Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors
    • W. Li, W. Wei, S. Zhu, J. Zhu, Y. Shi, T. Lin, E. Hao, A. Hayek, H. Deng, and S. Ding Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors Cell Stem Cell 4 2009 16 19
    • (2009) Cell Stem Cell , vol.4 , pp. 16-19
    • Li, W.1    Wei, W.2    Zhu, S.3    Zhu, J.4    Shi, Y.5    Lin, T.6    Hao, E.7    Hayek, A.8    Deng, H.9    Ding, S.10
  • 59
    • 35548941791 scopus 로고    scopus 로고
    • Beta-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells
    • R. Anton, H.A. Kestler, and M. Kuhl Beta-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells FEBS Lett. 581 2007 5247 5254
    • (2007) FEBS Lett. , vol.581 , pp. 5247-5254
    • Anton, R.1    Kestler, H.A.2    Kuhl, M.3
  • 61
    • 20744445658 scopus 로고    scopus 로고
    • Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development
    • C. Kemp, E. Willems, S. Abdo, L. Lambiv, and L. Leyns Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development Dev. Dyn. 233 2005 1064 1075
    • (2005) Dev. Dyn. , vol.233 , pp. 1064-1075
    • Kemp, C.1    Willems, E.2    Abdo, S.3    Lambiv, L.4    Leyns, L.5
  • 63
    • 79551594937 scopus 로고    scopus 로고
    • Beta-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
    • K.F. Kelly, D.Y. Ng, G. Jayakumaran, G.A. Wood, H. Koide, and B.W. Doble Beta-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism Cell Stem Cell 8 2011 214 227
    • (2011) Cell Stem Cell , vol.8 , pp. 214-227
    • Kelly, K.F.1    Ng, D.Y.2    Jayakumaran, G.3    Wood, G.A.4    Koide, H.5    Doble, B.W.6
  • 66
    • 79959999016 scopus 로고    scopus 로고
    • Differential requirement for the dual functions of beta-catenin in embryonic stem cell self-renewal and germ layer formation
    • N. Lyashenko, M. Winter, D. Migliorini, T. Biechele, R.T. Moon, and C. Hartmann Differential requirement for the dual functions of beta-catenin in embryonic stem cell self-renewal and germ layer formation Nat. Cell Biol. 13 2011 753 761
    • (2011) Nat. Cell Biol. , vol.13 , pp. 753-761
    • Lyashenko, N.1    Winter, M.2    Migliorini, D.3    Biechele, T.4    Moon, R.T.5    Hartmann, C.6
  • 67
    • 48449105489 scopus 로고    scopus 로고
    • Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal
    • F. Yi, L. Pereira, and B.J. Merrill Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal Stem Cells 26 2008 1951 1960
    • (2008) Stem Cells , vol.26 , pp. 1951-1960
    • Yi, F.1    Pereira, L.2    Merrill, B.J.3
  • 68
    • 33749645068 scopus 로고    scopus 로고
    • Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
    • L. Pereira, F. Yi, and B.J. Merrill Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal Mol. Cell. Biol. 26 2006 7479 7491
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 7479-7491
    • Pereira, L.1    Yi, F.2    Merrill, B.J.3
  • 69
    • 54849408417 scopus 로고    scopus 로고
    • T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways
    • W.L. Tam, C.Y. Lim, J. Han, J. Zhang, Y.S. Ang, H.H. Ng, H. Yang, and B. Lim T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways Stem Cells 26 2008 2019 2031
    • (2008) Stem Cells , vol.26 , pp. 2019-2031
    • Tam, W.L.1    Lim, C.Y.2    Han, J.3    Zhang, J.4    Ang, Y.S.5    Ng, H.H.6    Yang, H.7    Lim, B.8
  • 70
    • 41149174852 scopus 로고    scopus 로고
    • Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
    • M.F. Cole, S.E. Johnstone, J.J. Newman, M.H. Kagey, and R.A. Young Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells Genes Dev. 22 2008 746 755
    • (2008) Genes Dev. , vol.22 , pp. 746-755
    • Cole, M.F.1    Johnstone, S.E.2    Newman, J.J.3    Kagey, M.H.4    Young, R.A.5
  • 71
    • 77957876629 scopus 로고    scopus 로고
    • Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification
    • H. Hikasa, J. Ezan, K. Itoh, X. Li, M.W. Klymkowsky, and S.Y. Sokol Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification Dev. Cell 19 2010 521 532
    • (2010) Dev. Cell , vol.19 , pp. 521-532
    • Hikasa, H.1    Ezan, J.2    Itoh, K.3    Li, X.4    Klymkowsky, M.W.5    Sokol, S.Y.6
  • 72
    • 80053063127 scopus 로고    scopus 로고
    • Maintaining embryonic stem cell pluripotency with Wnt signaling
    • S.Y. Sokol Maintaining embryonic stem cell pluripotency with Wnt signaling Development 138 2011 4341 4350
    • (2011) Development , vol.138 , pp. 4341-4350
    • Sokol, S.Y.1
  • 73
    • 79953305300 scopus 로고    scopus 로고
    • Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2
    • H. Hikasa, and S.Y. Sokol Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2 J. Biol. Chem. 286 2011 12093 12100
    • (2011) J. Biol. Chem. , vol.286 , pp. 12093-12100
    • Hikasa, H.1    Sokol, S.Y.2
  • 74
    • 79959963618 scopus 로고    scopus 로고
    • Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
    • F. Yi, L. Pereira, J.A. Hoffman, B.R. Shy, C.M. Yuen, D.R. Liu, and B.J. Merrill Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal Nat. Cell Biol. 13 2011 762 770
    • (2011) Nat. Cell Biol. , vol.13 , pp. 762-770
    • Yi, F.1    Pereira, L.2    Hoffman, J.A.3    Shy, B.R.4    Yuen, C.M.5    Liu, D.R.6    Merrill, B.J.7
  • 76
    • 16844363879 scopus 로고    scopus 로고
    • Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation
    • A. Mansukhani, D. Ambrosetti, G. Holmes, L. Cornivelli, and C. Basilico Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation J. Cell Biol. 168 2005 1065 1076
    • (2005) J. Cell Biol. , vol.168 , pp. 1065-1076
    • Mansukhani, A.1    Ambrosetti, D.2    Holmes, G.3    Cornivelli, L.4    Basilico, C.5
  • 78
    • 77949881949 scopus 로고    scopus 로고
    • An expanded Oct4 interaction network: Implications for stem cell biology, development, and disease
    • M. Pardo, B. Lang, L. Yu, H. Prosser, A. Bradley, M.M. Babu, and J. Choudhary An expanded Oct4 interaction network: implications for stem cell biology, development, and disease Cell Stem Cell 6 2010 382 395
    • (2010) Cell Stem Cell , vol.6 , pp. 382-395
    • Pardo, M.1    Lang, B.2    Yu, L.3    Prosser, H.4    Bradley, A.5    Babu, M.M.6    Choudhary, J.7
  • 79
    • 34250793359 scopus 로고    scopus 로고
    • POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos
    • Y. Cao, D. Siegel, C. Donow, S. Knochel, L. Yuan, and W. Knochel POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos EMBO J. 26 2007 2942 2954
    • (2007) EMBO J. , vol.26 , pp. 2942-2954
    • Cao, Y.1    Siegel, D.2    Donow, C.3    Knochel, S.4    Yuan, L.5    Knochel, W.6
  • 81
    • 69949118280 scopus 로고    scopus 로고
    • Interplay of Oct4 with Sox2 and Sox17: A molecular switch from stem cell pluripotency to specifying a cardiac fate
    • S. Stefanovic, N. Abboud, S. Desilets, D. Nury, C. Cowan, and M. Puceat Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate J. Cell Biol. 186 2009 665 673
    • (2009) J. Cell Biol. , vol.186 , pp. 665-673
    • Stefanovic, S.1    Abboud, N.2    Desilets, S.3    Nury, D.4    Cowan, C.5    Puceat, M.6
  • 82
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 83
    • 77958569435 scopus 로고    scopus 로고
    • Induced pluripotency: History, mechanisms, and applications
    • M. Stadtfeld, and K. Hochedlinger Induced pluripotency: history, mechanisms, and applications Genes Dev. 24 2010 2239 2263
    • (2010) Genes Dev. , vol.24 , pp. 2239-2263
    • Stadtfeld, M.1    Hochedlinger, K.2
  • 85
    • 77953466536 scopus 로고    scopus 로고
    • Nuclear reprogramming to a pluripotent state by three approaches
    • S. Yamanaka, and H.M. Blau Nuclear reprogramming to a pluripotent state by three approaches Nature 465 2010 704 712
    • (2010) Nature , vol.465 , pp. 704-712
    • Yamanaka, S.1    Blau, H.M.2
  • 86
    • 54949127934 scopus 로고    scopus 로고
    • Periodic activation of Wnt/beta-catenin signaling enhances somatic cell reprogramming mediated by cell fusion
    • F. Lluis, E. Pedone, S. Pepe, and M.P. Cosma Periodic activation of Wnt/beta-catenin signaling enhances somatic cell reprogramming mediated by cell fusion Cell Stem Cell 3 2008 493 507
    • (2008) Cell Stem Cell , vol.3 , pp. 493-507
    • Lluis, F.1    Pedone, E.2    Pepe, S.3    Cosma, M.P.4
  • 87
    • 79961045254 scopus 로고    scopus 로고
    • T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications
    • F. Lluis, L. Ombrato, E. Pedone, S. Pepe, B.J. Merrill, and M.P. Cosma T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications Proc. Natl. Acad. Sci. U. S. A. 108 2011 11912 11917
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 11912-11917
    • Lluis, F.1    Ombrato, L.2    Pedone, E.3    Pepe, S.4    Merrill, B.J.5    Cosma, M.P.6
  • 88
    • 53349097675 scopus 로고    scopus 로고
    • Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration
    • A. Otto, C. Schmidt, G. Luke, S. Allen, P. Valasek, F. Muntoni, D. Lawrence-Watt, and K. Patel Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration J. Cell Sci. 121 2008 2939 2950
    • (2008) J. Cell Sci. , vol.121 , pp. 2939-2950
    • Otto, A.1    Schmidt, C.2    Luke, G.3    Allen, S.4    Valasek, P.5    Muntoni, F.6    Lawrence-Watt, D.7    Patel, K.8
  • 89
    • 66049092616 scopus 로고    scopus 로고
    • Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells
    • F. Le Grand, A.E. Jones, V. Seale, A. Scime, and M.A. Rudnicki Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells Cell Stem Cell 4 2009 535 547
    • (2009) Cell Stem Cell , vol.4 , pp. 535-547
    • Le Grand, F.1    Jones, A.E.2    Seale, V.3    Scime, A.4    Rudnicki, M.A.5
  • 91
    • 77956628008 scopus 로고    scopus 로고
    • Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture
    • Y.A. Zeng, and R. Nusse Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture Cell Stem Cell 6 2010 568 577
    • (2010) Cell Stem Cell , vol.6 , pp. 568-577
    • Zeng, Y.A.1    Nusse, R.2
  • 92
    • 0027945654 scopus 로고
    • Development of several organs that require inductive epithelial- mesenchymal interactions is impaired in LEF-1-deficient mice
    • C. van Genderen, R.M. Okamura, I. Farinas, R.G. Quo, T.G. Parslow, L. Bruhn, and R. Grosschedl Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice Genes Dev. 8 1994 2691 2703
    • (1994) Genes Dev. , vol.8 , pp. 2691-2703
    • Van Genderen, C.1    Okamura, R.M.2    Farinas, I.3    Quo, R.G.4    Parslow, T.G.5    Bruhn, L.6    Grosschedl, R.7
  • 93
    • 0032567078 scopus 로고    scopus 로고
    • De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • U. Gat, R. DasGupta, L. Degenstein, and E. Fuchs De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin Cell 95 1998 605 614
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    Dasgupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 94
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • T. Reya, and H. Clevers Wnt signalling in stem cells and cancer Nature 434 2005 843 850
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 96
    • 0016325705 scopus 로고
    • Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types
    • H. Cheng, and C.P. Leblond Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types Am. J. Anat. 141 1974 537 561
    • (1974) Am. J. Anat. , vol.141 , pp. 537-561
    • Cheng, H.1    Leblond, C.P.2
  • 97
    • 0016358918 scopus 로고
    • Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell
    • H. Cheng, and C.P. Leblond Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell Am. J. Anat. 141 1974 461 479
    • (1974) Am. J. Anat. , vol.141 , pp. 461-479
    • Cheng, H.1    Leblond, C.P.2
  • 98
    • 67651159312 scopus 로고    scopus 로고
    • Stem cells, self-renewal, and differentiation in the intestinal epithelium
    • L.G. van der Flier, and H. Clevers Stem cells, self-renewal, and differentiation in the intestinal epithelium Annu. Rev. Physiol. 71 2009 241 260
    • (2009) Annu. Rev. Physiol. , vol.71 , pp. 241-260
    • Van Der Flier, L.G.1    Clevers, H.2
  • 99
    • 84989436823 scopus 로고
    • Continuous labelling studies on mouse skin and intestine
    • C.S. Potten, L. Kovacs, and E. Hamilton Continuous labelling studies on mouse skin and intestine Cell Tissue Kinet. 7 1974 271 283
    • (1974) Cell Tissue Kinet. , vol.7 , pp. 271-283
    • Potten, C.S.1    Kovacs, L.2    Hamilton, E.3
  • 101
    • 80054041585 scopus 로고    scopus 로고
    • A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
    • H. Tian, B. Biehs, S. Warming, K.G. Leong, L. Rangell, O.D. Klein, and F.J. de Sauvage A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable Nature 478 2011 255 259
    • (2011) Nature , vol.478 , pp. 255-259
    • Tian, H.1    Biehs, B.2    Warming, S.3    Leong, K.G.4    Rangell, L.5    Klein, O.D.6    De Sauvage, F.J.7
  • 102
    • 46249128798 scopus 로고    scopus 로고
    • Bmi1 is expressed in vivo in intestinal stem cells
    • E. Sangiorgi, and M.R. Capecchi Bmi1 is expressed in vivo in intestinal stem cells Nat. Genet. 40 2008 915 920
    • (2008) Nat. Genet. , vol.40 , pp. 915-920
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 115
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • P.J. Morin, A.B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein, and K.W. Kinzler Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC Science 275 1997 1787 1790
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6    Kinzler, K.W.7
  • 120
    • 79953331014 scopus 로고    scopus 로고
    • Origin and maintenance of the intestinal cancer stem cell
    • E.J. Davies, V. Marsh, and A.R. Clarke Origin and maintenance of the intestinal cancer stem cell Mol. Carcinog. 50 2011 254 263
    • (2011) Mol. Carcinog. , vol.50 , pp. 254-263
    • Davies, E.J.1    Marsh, V.2    Clarke, A.R.3
  • 121
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: Premises, promises and challenges
    • H. Clevers The cancer stem cell: premises, promises and challenges Nat. Med. 17 2011 313 319
    • (2011) Nat. Med. , vol.17 , pp. 313-319
    • Clevers, H.1
  • 122
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • R. Nusse, and H.E. Varmus Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome Cell 31 1982 99 109
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2


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