-
1
-
-
0019133661
-
Mutations affecting segment number and polarity in Drosophila
-
C. Nusslein-Volhard, and E. Wieschaus Mutations affecting segment number and polarity in Drosophila Nature 287 1980 795 801
-
(1980)
Nature
, vol.287
, pp. 795-801
-
-
Nusslein-Volhard, C.1
Wieschaus, E.2
-
2
-
-
0034574602
-
The establishment of Spemann's organizer and patterning of the vertebrate embryo
-
E.M. De Robertis, J. Larrain, M. Oelgeschlager, and O. Wessely The establishment of Spemann's organizer and patterning of the vertebrate embryo Nat Rev Genet 1 2000 171 181
-
(2000)
Nat Rev Genet
, vol.1
, pp. 171-181
-
-
De Robertis, E.M.1
Larrain, J.2
Oelgeschlager, M.3
Wessely, O.4
-
3
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
C.Y. Logan, and R. Nusse The Wnt signaling pathway in development and disease Annu Rev Cell Dev Biol 20 2004 781 810
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
4
-
-
4043181214
-
Cancer genes and the pathways they control
-
B. Vogelstein, and K.W. Kinzler Cancer genes and the pathways they control Nat Med 10 2004 789 799
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
5
-
-
0035479835
-
New aspects of Wnt signaling pathways in higher vertebrates
-
J. Huelsken, and W. Birchmeier New aspects of Wnt signaling pathways in higher vertebrates Curr Opin Genet Dev 11 2001 547 553
-
(2001)
Curr Opin Genet Dev
, vol.11
, pp. 547-553
-
-
Huelsken, J.1
Birchmeier, W.2
-
6
-
-
0035806989
-
Heads or tails: Wnts and anterior-posterior patterning
-
T.P. Yamaguchi Heads or tails: Wnts and anterior-posterior patterning Curr Biol 11 2001 R713 R724
-
(2001)
Curr Biol
, vol.11
-
-
Yamaguchi, T.P.1
-
7
-
-
0037205007
-
The promise and perils of Wnt signaling through β-catenin
-
R.T. Moon, B. Bowerman, M. Boutros, and N. Perrimon The promise and perils of Wnt signaling through β-catenin Science 296 2002 1644 1646
-
(2002)
Science
, vol.296
, pp. 1644-1646
-
-
Moon, R.T.1
Bowerman, B.2
Boutros, M.3
Perrimon, N.4
-
8
-
-
34250134008
-
Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. II. Zygotic Loci on the third chromosome
-
G. Jürgens, H. Kluding, C. Nüsslein-Volhard, and E. Wieschaus Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. II. Zygotic Loci on the third chromosome Roux Arch DevBiol 193 1984 283 295
-
(1984)
Roux Arch DevBiol
, vol.193
, pp. 283-295
-
-
Jürgens, G.1
Kluding, H.2
Nüsslein-Volhard, C.3
Wieschaus, E.4
-
9
-
-
0022993985
-
Plakoglobin: A protein common to different kinds of intercellular adhering junctions
-
P. Cowin, H.P. Kapprell, W.W. Franke, J. Tamkun, and R.O. Hynes Plakoglobin: a protein common to different kinds of intercellular adhering junctions Cell 46 1986 1063 1073
-
(1986)
Cell
, vol.46
, pp. 1063-1073
-
-
Cowin, P.1
Kapprell, H.P.2
Franke, W.W.3
Tamkun, J.4
Hynes, R.O.5
-
10
-
-
0024451982
-
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
-
M. Ozawa, H. Baribault, and R. Kemler The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species EMBO J 8 1989 1711 1717
-
(1989)
EMBO J
, vol.8
, pp. 1711-1717
-
-
Ozawa, M.1
Baribault, H.2
Kemler, R.3
-
11
-
-
0026316099
-
A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin
-
P.D. McCrea, C.W. Turck, and B. Gumbiner A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin Science 254 1991 1359 1361
-
(1991)
Science
, vol.254
, pp. 1359-1361
-
-
McCrea, P.D.1
Turck, C.W.2
Gumbiner, B.3
-
12
-
-
0027185632
-
From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
-
R. Kemler From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion Trends Genet 9 1993 317 321
-
(1993)
Trends Genet
, vol.9
, pp. 317-321
-
-
Kemler, R.1
-
13
-
-
0029160437
-
Morphogenetic roles of classic cadherins
-
M. Takeichi Morphogenetic roles of classic cadherins Curr Opin Cell Biol 7 1995 619 627
-
(1995)
Curr Opin Cell Biol
, vol.7
, pp. 619-627
-
-
Takeichi, M.1
-
15
-
-
28344433073
-
Deconstructing the cadherin-catenin-actin Complex
-
••] demonstrate that the E-cadherin-β-catenin-α-catenin complex at the adherens junctions forms a dynamic link to the cytoskeleton. It is shown that α-catenin does not directly bind actin, but that α-catenin influences Arp2/3-induced actin polymerization.
-
(2005)
Cell
, vol.123
, pp. 889-901
-
-
Yamada, S.1
Pokutta, S.2
Drees, F.3
Weis, W.I.4
Nelson, M.5
-
16
-
-
0029781509
-
Functional interaction of β-catenin with the transcription factor LEF-1
-
J. Behrens, J.P. von Kries, M. Kuhl, L. Bruhn, D. Wedlich, R. Grosschedl, and W. Birchmeier Functional interaction of β-catenin with the transcription factor LEF-1 Nature 382 1996 638 642
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
Von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
17
-
-
0345343608
-
Nuclear localization of β-catenin by interaction with transcription factor LEF-1
-
O. Huber, R. Korn, J. McLaughlin, M. Ohsugi, B.G. Herrmann, and R. Kemler Nuclear localization of β-catenin by interaction with transcription factor LEF-1 Mech Dev 59 1996 3 10
-
(1996)
Mech Dev
, vol.59
, pp. 3-10
-
-
Huber, O.1
Korn, R.2
McLaughlin, J.3
Ohsugi, M.4
Herrmann, B.G.5
Kemler, R.6
-
18
-
-
0001003110
-
XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos
-
M. Molenaar, M. van de Wetering, M. Oosterwegel, J. Peterson-Maduro, S. Godsave, V. Korinek, J. Roose, O. Destree, and H. Clevers XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos Cell 86 1996 391 399
-
(1996)
Cell
, vol.86
, pp. 391-399
-
-
Molenaar, M.1
Van De Wetering, M.2
Oosterwegel, M.3
Peterson-Maduro, J.4
Godsave, S.5
Korinek, V.6
Roose, J.7
Destree, O.8
Clevers, H.9
-
19
-
-
0033119801
-
β-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
O. Tetsu, and F. McCormick β-catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 1999 422 426
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
20
-
-
0026726952
-
Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas
-
S. Cottrell, D. Bicknell, L. Kaklamanis, and W.F. Bodmer Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas Lancet 340 1992 626 630
-
(1992)
Lancet
, vol.340
, pp. 626-630
-
-
Cottrell, S.1
Bicknell, D.2
Kaklamanis, L.3
Bodmer, W.F.4
-
21
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
S.M. Powell, N. Zilz, Y. Beazer-Barclay, T.M. Bryan, S.R. Hamilton, S.N. Thibodeau, B. Vogelstein, and K.W. Kinzler APC mutations occur early during colorectal tumorigenesis Nature 359 1992 235 237
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
22
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
-
P.J. Morin, A.B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein, and K.W. Kinzler Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC Science 275 1997 1787 1790
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
23
-
-
0033895709
-
Wnt signaling and cancer
-
P. Polakis Wnt signaling and cancer Genes Dev 14 2000 1837 1851
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
24
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
M. Bienz, and H. Clevers Linking colorectal cancer to Wnt signaling Cell 103 2000 311 320
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
25
-
-
0028987249
-
Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
-
S. Munemitsu, I. Albert, B. Souza, B. Rubinfeld, and P. Polakis Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein Proc Natl Acad Sci USA 92 1995 3046 3050
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3046-3050
-
-
Munemitsu, S.1
Albert, I.2
Souza, B.3
Rubinfeld, B.4
Polakis, P.5
-
26
-
-
2642698862
-
APC gene: Database of germline and somatic mutations in human tumors and cell lines
-
P. Laurent-Puig, C. Beroud, and T. Soussi APC gene: database of germline and somatic mutations in human tumors and cell lines Nucleic Acids Res 26 1998 269 270
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 269-270
-
-
Laurent-Puig, P.1
Beroud, C.2
Soussi, T.3
-
27
-
-
0033780630
-
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling
-
W. Liu, X. Dong, M. Mai, R.S. Seelan, K. Taniguchi, K.K. Krishnadath, K.C. Halling, J.M. Cunningham, L.A. Boardman, and C. Qian Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling Nat Genet 26 2000 146 147
-
(2000)
Nat Genet
, vol.26
, pp. 146-147
-
-
Liu, W.1
Dong, X.2
Mai, M.3
Seelan, R.S.4
Taniguchi, K.5
Krishnadath, K.K.6
Halling, K.C.7
Cunningham, J.M.8
Boardman, L.A.9
Qian, C.10
-
28
-
-
0034088858
-
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
-
S. Satoh, Y. Daigo, Y. Furukawa, T. Kato, N. Miwa, T. Nishiwaki, T. Kawasoe, H. Ishiguro, M. Fujita, and T. Tokino AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1 Nat Genet 24 2000 245 250
-
(2000)
Nat Genet
, vol.24
, pp. 245-250
-
-
Satoh, S.1
Daigo, Y.2
Furukawa, Y.3
Kato, T.4
Miwa, N.5
Nishiwaki, T.6
Kawasoe, T.7
Ishiguro, H.8
Fujita, M.9
Tokino, T.10
-
29
-
-
0242268881
-
Detection of point mutations of the Axin1 gene in colorectal cancers
-
L.H. Jin, Q.J. Shao, W. Luo, Z.Y. Ye, Q. Li, and S.C. Lin Detection of point mutations of the Axin1 gene in colorectal cancers Int J Cancer 107 2003 696 699
-
(2003)
Int J Cancer
, vol.107
, pp. 696-699
-
-
Jin, L.H.1
Shao, Q.J.2
Luo, W.3
Ye, Z.Y.4
Li, Q.5
Lin, S.C.6
-
30
-
-
0030900696
-
Stabilization of β-catenin by genetic defects in melanoma cell lines
-
B. Rubinfeld, P. Robbins, M. El Gamil, I. Albert, E. Porfiri, and P. Polakis Stabilization of β-catenin by genetic defects in melanoma cell lines Science 275 1997 1790 1792
-
(1997)
Science
, vol.275
, pp. 1790-1792
-
-
Rubinfeld, B.1
Robbins, P.2
El Gamil, M.3
Albert, I.4
Porfiri, E.5
Polakis, P.6
-
31
-
-
0033536185
-
β-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity
-
P. Legoix, O. Bluteau, J. Bayer, C. Perret, C. Balabaud, J. Belghiti, D. Franco, G. Thomas, P. Laurent-Puig, and J. Zucman-Rossi β-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity Oncogene 18 1999 4044 4046
-
(1999)
Oncogene
, vol.18
, pp. 4044-4046
-
-
Legoix, P.1
Bluteau, O.2
Bayer, J.3
Perret, C.4
Balabaud, C.5
Belghiti, J.6
Franco, D.7
Thomas, G.8
Laurent-Puig, P.9
Zucman-Rossi, J.10
-
32
-
-
0033119582
-
β-catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas
-
W.S. Samowitz, M.D. Powers, L.N. Spirio, F. Nollet, F. Van Roy, and M.L. Slattery β-catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas Cancer Res 59 1999 1442 1444
-
(1999)
Cancer Res
, vol.59
, pp. 1442-1444
-
-
Samowitz, W.S.1
Powers, M.D.2
Spirio, L.N.3
Nollet, F.4
Van Roy, F.5
Slattery, M.L.6
-
33
-
-
0027401607
-
The multistep nature of cancer
-
B. Vogelstein, and K.W. Kinzler The multistep nature of cancer Trends Genet 9 1993 138 141
-
(1993)
Trends Genet
, vol.9
, pp. 138-141
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
34
-
-
0035496104
-
APC, signal transduction and genetic instability in colorectal cancer
-
R. Fodde, R. Smits, and H. Clevers APC, signal transduction and genetic instability in colorectal cancer Nat Rev Cancer 1 2001 55 67
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 55-67
-
-
Fodde, R.1
Smits, R.2
Clevers, H.3
-
35
-
-
0035964349
-
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
-
T. Brabletz, A. Jung, S. Reu, M. Porzner, F. Hlubek, L.A. Kunz-Schughart, R. Knuechel, and T. Kirchner Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment Proc Natl Acad Sci USA 98 2001 10356 10361
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10356-10361
-
-
Brabletz, T.1
Jung, A.2
Reu, S.3
Porzner, M.4
Hlubek, F.5
Kunz-Schughart, L.A.6
Knuechel, R.7
Kirchner, T.8
-
36
-
-
0029553183
-
An overview of epithelio-mesenchymal transformation
-
E.D. Hay An overview of epithelio-mesenchymal transformation Acta Anat (Basel) 154 1995 8 20
-
(1995)
Acta Anat (Basel)
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
37
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
J.P. Thiery Epithelial-mesenchymal transitions in tumour progression Nat Rev Cancer 2 2002 442 454
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
38
-
-
0345601083
-
Met, metastasis, motility and more
-
C. Birchmeier, W. Birchmeier, E. Gherardi, and G.F. Vande Woude Met, metastasis, motility and more Nat Rev Mol Cell Biol 4 2003 915 925
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Woude, G.F.4
-
39
-
-
0024383791
-
Dissecting tumor cell invasion: Epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion
-
J. Behrens, M.M. Mareel, F.M. Van Roy, and W. Birchmeier Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion J Cell Biol 108 1989 2435 2447
-
(1989)
J Cell Biol
, vol.108
, pp. 2435-2447
-
-
Behrens, J.1
Mareel, M.M.2
Van Roy, F.M.3
Birchmeier, W.4
-
40
-
-
0025818032
-
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
-
K. Vleminckx, L. Vakaet Jr., M. Mareel, W. Fiers, and F. Van Roy Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role Cell 66 1991 107 119
-
(1991)
Cell
, vol.66
, pp. 107-119
-
-
Vleminckx, K.1
Vakaet Jr., L.2
Mareel, M.3
Fiers, W.4
Van Roy, F.5
-
41
-
-
0027507028
-
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
-
J. Behrens, L. Vakaet, R. Friis, E. Winterhager, F. Van Roy, M.M. Mareel, and W. Birchmeier Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-SRC gene J Cell Biol 120 1993 757 766
-
(1993)
J Cell Biol
, vol.120
, pp. 757-766
-
-
Behrens, J.1
Vakaet, L.2
Friis, R.3
Winterhager, E.4
Van Roy, F.5
Mareel, M.M.6
Birchmeier, W.7
-
42
-
-
0032510494
-
A causal role for E-cadherin in the transition from adenoma to carcinoma
-
A.K. Perl, P. Wilgenbus, U. Dahl, H. Semb, and G. Christofori A causal role for E-cadherin in the transition from adenoma to carcinoma Nature 392 1998 190 193
-
(1998)
Nature
, vol.392
, pp. 190-193
-
-
Perl, A.K.1
Wilgenbus, P.2
Dahl, U.3
Semb, H.4
Christofori, G.5
-
43
-
-
0033579480
-
Regulation of E-cadherin/Catenin association by tyrosine phosphorylation
-
S. Roura, S. Miravet, J. Piedra, A. Garcia de Herreros, and M. Dunach Regulation of E-cadherin/Catenin association by tyrosine phosphorylation J Biol Chem 274 1999 36734 36740
-
(1999)
J Biol Chem
, vol.274
, pp. 36734-36740
-
-
Roura, S.1
Miravet, S.2
Piedra, J.3
Garcia De Herreros, A.4
Dunach, M.5
-
44
-
-
0036121308
-
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
-
Y. Fujita, G. Krause, M. Scheffner, D. Zechner, H.E. Leddy, J. Behrens, T. Sommer, and W. Birchmeier Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex Nat Cell Biol 4 2002 222 231
-
(2002)
Nat Cell Biol
, vol.4
, pp. 222-231
-
-
Fujita, Y.1
Krause, G.2
Scheffner, M.3
Zechner, D.4
Leddy, H.E.5
Behrens, J.6
Sommer, T.7
Birchmeier, W.8
-
45
-
-
0037378505
-
P120 Catenin-associated Fer and Fyn tyrosine kinases regulate β-catenin Tyr-142 phosphorylation and β-catenin-α-catenin Interaction
-
J. Piedra, S. Miravet, J. Castano, H.G. Palmer, N. Heisterkamp, A. Garcia de Herreros, and M. Dunach p120 Catenin-associated Fer and Fyn tyrosine kinases regulate β-catenin Tyr-142 phosphorylation and β-catenin-α- catenin Interaction Mol Cell Biol 23 2003 2287 2297
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2287-2297
-
-
Piedra, J.1
Miravet, S.2
Castano, J.3
Palmer, H.G.4
Heisterkamp, N.5
Garcia De Herreros, A.6
Dunach, M.7
-
46
-
-
24644447079
-
The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of β-catenin
-
J. Lilien, and J. Balsamo The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of β-catenin Curr Opin Cell Biol 17 2005 459 465
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 459-465
-
-
Lilien, J.1
Balsamo, J.2
-
47
-
-
10344220547
-
Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele
-
C. Graveel, Y. Su, J. Koeman, L.M. Wang, L. Tessarollo, M. Fiscella, C. Birchmeier, P. Swiatek, R. Bronson, and W.G. Vande Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele Proc Natl Acad Sci USA 101 2004 17198 17203
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17198-17203
-
-
Graveel, C.1
Su, Y.2
Koeman, J.3
Wang, L.M.4
Tessarollo, L.5
Fiscella, M.6
Birchmeier, C.7
Swiatek, P.8
Bronson, R.9
Vande, W.G.10
-
48
-
-
2442648882
-
Mutational analysis of the tyrosine phosphatome in colorectal cancers
-
Z. Wang, D. Shen, D.W. Parsons, A. Bardelli, J. Sager, S. Szabo, J. Ptak, N. Silliman, B.A. Peters, and M.S. van der Heijden Mutational analysis of the tyrosine phosphatome in colorectal cancers Science 304 2004 1164 1166 This study characterizes somatic mutations in tyrosine phosphatase genes that are found in 26% of colorectal cancers. The authors suggest that mutated tyrosine phosphatases may act as tumor suppressor genes.
-
(2004)
Science
, vol.304
, pp. 1164-1166
-
-
Wang, Z.1
Shen, D.2
Parsons, D.W.3
Bardelli, A.4
Sager, J.5
Szabo, S.6
Ptak, J.7
Silliman, N.8
Peters, B.A.9
Van Der Heijden, M.S.10
-
49
-
-
0032891720
-
E-cadherin binding prevents β-catenin nuclear localization and β-catenin/LEF-1-mediated transactivation
-
S. Orsulic, O. Huber, H. Aberle, S. Arnold, and R. Kemler E-cadherin binding prevents β-catenin nuclear localization and β-catenin/LEF-1- mediated transactivation J Cell Sci 112 1999 1237 1245
-
(1999)
J Cell Sci
, vol.112
, pp. 1237-1245
-
-
Orsulic, S.1
Huber, O.2
Aberle, H.3
Arnold, S.4
Kemler, R.5
-
50
-
-
0035904231
-
E-cadherin regulates cell growth by modulating proliferation-dependent β-catenin transcriptional activity
-
A. Stockinger, A. Eger, J. Wolf, H. Beug, and R. Foisner E-cadherin regulates cell growth by modulating proliferation-dependent β-catenin transcriptional activity J Cell Biol 154 2001 1185 1196
-
(2001)
J Cell Biol
, vol.154
, pp. 1185-1196
-
-
Stockinger, A.1
Eger, A.2
Wolf, J.3
Beug, H.4
Foisner, R.5
-
51
-
-
0035947772
-
E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion-independent manner
-
C.J. Gottardi, E. Wong, and B.M. Gumbiner E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion-independent manner J Cell Biol 153 2001 1049 1060
-
(2001)
J Cell Biol
, vol.153
, pp. 1049-1060
-
-
Gottardi, C.J.1
Wong, E.2
Gumbiner, B.M.3
-
52
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
-
J. Behrens, B.A. Jerchow, M. Wurtele, J. Grimm, C. Asbrand, R. Wirtz, M. Kuhl, D. Wedlich, and W. Birchmeier Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β Science 280 1998 596 599
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
Grimm, J.4
Asbrand, C.5
Wirtz, R.6
Kuhl, M.7
Wedlich, D.8
Birchmeier, W.9
-
53
-
-
0032079884
-
Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin
-
S. Kishida, H. Yamamoto, S. Ikeda, M. Kishida, I. Sakamoto, S. Koyama, and A. Kikuchi Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin J Biol Chem 273 1998 10823 10826
-
(1998)
J Biol Chem
, vol.273
, pp. 10823-10826
-
-
Kishida, S.1
Yamamoto, H.2
Ikeda, S.3
Kishida, M.4
Sakamoto, I.5
Koyama, S.6
Kikuchi, A.7
-
54
-
-
0037155691
-
Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
-
C. Liu, Y. Li, M. Semenov, C. Han, G.H. Baeg, Y. Tan, Z. Zhang, X. Lin, and X. He Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism Cell 108 2002 837 847
-
(2002)
Cell
, vol.108
, pp. 837-847
-
-
Liu, C.1
Li, Y.2
Semenov, M.3
Han, C.4
Baeg, G.H.5
Tan, Y.6
Zhang, Z.7
Lin, X.8
He, X.9
-
55
-
-
0037102507
-
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling
-
T. Schwarz-Romond, C. Asbrand, J. Bakkers, M. Kuhl, H.J. Schaeffer, J. Huelsken, J. Behrens, M. Hammerschmidt, and W. Birchmeier The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling Genes Dev 16 2002 2073 2084
-
(2002)
Genes Dev
, vol.16
, pp. 2073-2084
-
-
Schwarz-Romond, T.1
Asbrand, C.2
Bakkers, J.3
Kuhl, M.4
Schaeffer, H.J.5
Huelsken, J.6
Behrens, J.7
Hammerschmidt, M.8
Birchmeier, W.9
-
56
-
-
0031856533
-
Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with β-catenin
-
S.C. Hsu, J. Galceran, and R. Grosschedl Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with β-catenin Mol Cell Biol 18 1998 4807 4818
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4807-4818
-
-
Hsu, S.C.1
Galceran, J.2
Grosschedl, R.3
-
57
-
-
0034232066
-
Curbing the nuclear activities of β-catenin. Control over Wnt target gene expression
-
A. Hecht, and R. Kemler Curbing the nuclear activities of β-catenin. Control over Wnt target gene expression EMBO Rep 1 2000 24 28
-
(2000)
EMBO Rep
, vol.1
, pp. 24-28
-
-
Hecht, A.1
Kemler, R.2
-
58
-
-
0033580842
-
Functional characterization of multiple transactivating elements in β-catenin, some of which interact with the TATA-binding protein in vitro
-
A. Hecht, C.M. Litterst, O. Huber, and R. Kemler Functional characterization of multiple transactivating elements in β-catenin, some of which interact with the TATA-binding protein in vitro J Biol Chem 274 1999 18017 18025
-
(1999)
J Biol Chem
, vol.274
, pp. 18017-18025
-
-
Hecht, A.1
Litterst, C.M.2
Huber, O.3
Kemler, R.4
-
59
-
-
0034678610
-
The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates
-
A. Hecht, K. Vleminckx, M.P. Stemmler, F. Van Roy, and R. Kemler The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates EMBO J 19 2000 1839 1850
-
(2000)
EMBO J
, vol.19
, pp. 1839-1850
-
-
Hecht, A.1
Vleminckx, K.2
Stemmler, M.P.3
Van Roy, F.4
Kemler, R.5
-
60
-
-
0033741508
-
Regulation of β -catenin transformation by the p300 transcriptional coactivator
-
Y. Sun, F.T. Kolligs, M.O. Hottiger, R. Mosavin, E.R. Fearon, and G.J. Nabel Regulation of β -catenin transformation by the p300 transcriptional coactivator Proc Natl Acad Sci USA 97 2000 12613 12618
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12613-12618
-
-
Sun, Y.1
Kolligs, F.T.2
Hottiger, M.O.3
Mosavin, R.4
Fearon, E.R.5
Nabel, G.J.6
-
61
-
-
0034678357
-
The transcriptional coactivator CBP interacts with β-catenin to activate gene expression
-
K.I. Takemaru, and R.T. Moon The transcriptional coactivator CBP interacts with β-catenin to activate gene expression J Cell Biol 149 2000 249 254
-
(2000)
J Cell Biol
, vol.149
, pp. 249-254
-
-
Takemaru, K.I.1
Moon, R.T.2
-
62
-
-
0035801499
-
The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation
-
N. Barker, A. Hurlstone, H. Musisi, A. Miles, M. Bienz, and H. Clevers The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation EMBO J 20 2001 4935 4943
-
(2001)
EMBO J
, vol.20
, pp. 4935-4943
-
-
Barker, N.1
Hurlstone, A.2
Musisi, H.3
Miles, A.4
Bienz, M.5
Clevers, H.6
-
63
-
-
0034669058
-
Pontin52 and reptin52 function as antagonistic regulators of β-catenin signalling activity
-
A. Bauer, S. Chauvet, O. Huber, F. Usseglio, U. Rothbacher, D. Aragnol, R. Kemler, and J. Pradel Pontin52 and reptin52 function as antagonistic regulators of β-catenin signalling activity EMBO J 19 2000 6121 6130
-
(2000)
EMBO J
, vol.19
, pp. 6121-6130
-
-
Bauer, A.1
Chauvet, S.2
Huber, O.3
Usseglio, F.4
Rothbacher, U.5
Aragnol, D.6
Kemler, R.7
Pradel, J.8
-
64
-
-
0034212391
-
Expression of Xenopus homologs of the β-catenin binding protein pontin52
-
C. Etard, D. Wedlich, A. Bauer, O. Huber, and M. Kuhl Expression of Xenopus homologs of the β-catenin binding protein pontin52 Mech Dev 94 2000 219 222
-
(2000)
Mech Dev
, vol.94
, pp. 219-222
-
-
Etard, C.1
Wedlich, D.2
Bauer, A.3
Huber, O.4
Kuhl, M.5
-
65
-
-
23844454900
-
Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development
-
P. Bellosta, T. Hulf, S.B. Diop, F. Usseglio, J. Pradel, D. Aragnol, and P. Gallant Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development Proc Natl Acad Sci USA 102 2005 11799 11804
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11799-11804
-
-
Bellosta, P.1
Hulf, T.2
Diop, S.B.3
Usseglio, F.4
Pradel, J.5
Aragnol, D.6
Gallant, P.7
-
66
-
-
15944367756
-
Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1
-
C. Etard, D. Gradl, M. Kunz, M. Eilers, and D. Wedlich Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1 Mech Dev 122 2005 545 556
-
(2005)
Mech Dev
, vol.122
, pp. 545-556
-
-
Etard, C.1
Gradl, D.2
Kunz, M.3
Eilers, M.4
Wedlich, D.5
-
67
-
-
19944425163
-
Kaiso/p120-catenin and TCF/β-catenin complexes coordinately regulate canonical Wnt gene targets
-
J.I. Park, S.W. Kim, J.P. Lyons, H. Ji, T.T. Nguyen, K. Cho, M.C. Barton, T. Deroo, K. Vleminckx, R.T. Moon, and P.D. McCrea Kaiso/p120-catenin and TCF/β-catenin complexes coordinately regulate canonical Wnt gene targets Dev Cell 8 2005 843 854 In this study, the authors demonstrate that the zinc finger protein Kaiso directly represses canonical Wnt-signaling in Xenopus embryos. This repression can be relieved by binding of Kaiso to p120-catenin. This work thereby proposes a putative parallel pathway of Wnt-β-catenin signaling and of p120-catenin-Kaiso that may be involved in development and tumorigenesis.
-
(2005)
Dev Cell
, vol.8
, pp. 843-854
-
-
Park, J.I.1
Kim, S.W.2
Lyons, J.P.3
Ji, H.4
Nguyen, T.T.5
Cho, K.6
Barton, M.C.7
Deroo, T.8
Vleminckx, K.9
Moon, R.T.10
McCrea, P.D.11
-
68
-
-
16344366009
-
The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the β-catenin/TCF target gene matrilysin
-
C.M. Spring, K.F. Kelly, I. O'Kelly, M. Graham, H.C. Crawford, and J.M. Daniel The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the β-catenin/TCF target gene matrilysin Exp Cell Res 305 2005 253 265
-
(2005)
Exp Cell Res
, vol.305
, pp. 253-265
-
-
Spring, C.M.1
Kelly, K.F.2
O'Kelly, I.3
Graham, M.4
Crawford, H.C.5
Daniel, J.M.6
-
69
-
-
0032189630
-
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling
-
L. Waltzer, and M. Bienz Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling Nature 395 1998 521 525
-
(1998)
Nature
, vol.395
, pp. 521-525
-
-
Waltzer, L.1
Bienz, M.2
-
70
-
-
0030061120
-
Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to α-catenin
-
H. Aberle, H. Schwartz, H. Hoschuetzky, and R. Kemler Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to α-catenin J Biol Chem 271 1996 1520 1526
-
(1996)
J Biol Chem
, vol.271
, pp. 1520-1526
-
-
Aberle, H.1
Schwartz, H.2
Hoschuetzky, H.3
Kemler, R.4
-
71
-
-
0033695362
-
Structure of the dimerization and β-catenin-binding region of α-catenin
-
S. Pokutta, and W.I. Weis Structure of the dimerization and β-catenin-binding region of α-catenin Mol Cell 5 2000 533 543
-
(2000)
Mol Cell
, vol.5
, pp. 533-543
-
-
Pokutta, S.1
Weis, W.I.2
-
72
-
-
0035827543
-
Regulation of β-catenin structure and activity by tyrosine phosphorylation
-
J. Piedra, D. Martinez, J. Castano, S. Miravet, M. Dunach, and A.G. de Herreros Regulation of β-catenin structure and activity by tyrosine phosphorylation J Biol Chem 276 2001 20436 20443
-
(2001)
J Biol Chem
, vol.276
, pp. 20436-20443
-
-
Piedra, J.1
Martinez, D.2
Castano, J.3
Miravet, S.4
Dunach, M.5
De Herreros, A.G.6
-
73
-
-
0034601478
-
Distinct β-catenins mediate adhesion and signalling functions in C. elegans
-
H.C. Korswagen, M.A. Herman, and H.C. Clevers Distinct β-catenins mediate adhesion and signalling functions in C. elegans Nature 406 2000 527 532
-
(2000)
Nature
, vol.406
, pp. 527-532
-
-
Korswagen, H.C.1
Herman, M.A.2
Clevers, H.C.3
-
74
-
-
0037199939
-
β-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to β-catenin
-
J. Castano, I. Raurell, J.A. Piedra, S. Miravet, M. Dunach, and A. Garcia de Herreros β-catenin N- and C-terminal tails modulate the coordinated binding of adherens junction proteins to β-catenin J Biol Chem 277 2002 31541 31550
-
(2002)
J Biol Chem
, vol.277
, pp. 31541-31550
-
-
Castano, J.1
Raurell, I.2
Piedra, J.A.3
Miravet, S.4
Dunach, M.5
Garcia De Herreros, A.6
-
75
-
-
0033635606
-
Crystal structure of a β-catenin/Tcf complex
-
T.A. Graham, C. Weaver, F. Mao, D. Kimelman, and W. Xu Crystal structure of a β-catenin/Tcf complex Cell 103 2000 885 896
-
(2000)
Cell
, vol.103
, pp. 885-896
-
-
Graham, T.A.1
Weaver, C.2
Mao, F.3
Kimelman, D.4
Xu, W.5
-
76
-
-
0033813426
-
Hot spots in β-catenin for interactions with LEF-1, conductin and APC
-
J.P. von Kries, G. Winbeck, C. Asbrand, T. Schwarz-Romond, N. Sochnikova, A. Dell'Oro, J. Behrens, and W. Birchmeier Hot spots in β-catenin for interactions with LEF-1, conductin and APC Nat Struct Biol 7 2000 800 807
-
(2000)
Nat Struct Biol
, vol.7
, pp. 800-807
-
-
Von Kries, J.P.1
Winbeck, G.2
Asbrand, C.3
Schwarz-Romond, T.4
Sochnikova, N.5
Dell'Oro, A.6
Behrens, J.7
Birchmeier, W.8
-
77
-
-
0035805117
-
The structure of the β-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by β-catenin
-
A.H. Huber, and W.I. Weis The structure of the β-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by β-catenin Cell 105 2001 391 402
-
(2001)
Cell
, vol.105
, pp. 391-402
-
-
Huber, A.H.1
Weis, W.I.2
-
78
-
-
4444276194
-
Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions
-
F.H. Brembeck, T. Schwarz-Romond, J. Bakkers, S. Wilhelm, M. Hammerschmidt, and W. Birchmeier Essential role of BCL9-2 in the switch between β-catenin's adhesive and transcriptional functions Genes Dev 18 2004 2225 2230 This study demonstrates that the switch between adhesion and transcription of β-catenin is modulated by phosphorylation of tyrosine 142 in β-catenin, which induces BCL9-2 binding and inhibits the interaction with α-catenin. Moreover, BCL9-2 was shown to be required for EMT, for cellular transformation and for the nuclear localization of β-catenin. These data point to a possible role of BCL9-2 in tumorigenesis.
-
(2004)
Genes Dev
, vol.18
, pp. 2225-2230
-
-
Brembeck, F.H.1
Schwarz-Romond, T.2
Bakkers, J.3
Wilhelm, S.4
Hammerschmidt, M.5
Birchmeier, W.6
-
79
-
-
4344618740
-
Continuous association of cadherin with β-catenin requires the non-receptor tyrosine-kinase Fer
-
G. Xu, A.W. Craig, P. Greer, M. Miller, P.Z. Anastasiadis, J. Lilien, and J. Balsamo Continuous association of cadherin with β-catenin requires the non-receptor tyrosine-kinase Fer J Cell Sci 117 2004 3207 3219 This study demonstrates that tyrosine phosphorylation of β-catenin is regulated by the tyrosine kinase Fer and the protein tyrosine phosphatase PTP1B. Fer is shown to phosphorylate PTP1B and thereby enable binding of PTP1B to the cytoplasmic domain of E-cadherin. PTP1B is proposed to then maintain β-catenin in a dephosphorylated state.
-
(2004)
J Cell Sci
, vol.117
, pp. 3207-3219
-
-
Xu, G.1
Craig, A.W.2
Greer, P.3
Miller, M.4
Anastasiadis, P.Z.5
Lilien, J.6
Balsamo, J.7
-
80
-
-
0037023584
-
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex
-
T. Kramps, O. Peter, E. Brunner, D. Nellen, B. Froesch, S. Chatterjee, M. Murone, S. Zullig, and K. Basler Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex Cell 109 2002 47 60
-
(2002)
Cell
, vol.109
, pp. 47-60
-
-
Kramps, T.1
Peter, O.2
Brunner, E.3
Nellen, D.4
Froesch, B.5
Chatterjee, S.6
Murone, M.7
Zullig, S.8
Basler, K.9
-
81
-
-
0036713566
-
Pygopus Encodes a nuclear protein essential for wingless/Wnt signaling
-
T.Y. Belenkaya, C. Han, H.J. Standley, X. Lin, D.W. Houston, J. Heasman, and X. Lin pygopus Encodes a nuclear protein essential for wingless/Wnt signaling Development 129 2002 4089 4101
-
(2002)
Development
, vol.129
, pp. 4089-4101
-
-
Belenkaya, T.Y.1
Han, C.2
Standley, H.J.3
Lin, X.4
Houston, D.W.5
Heasman, J.6
Lin, X.7
-
82
-
-
0036333382
-
Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila
-
D.S. Parker, J. Jemison, and K.M. Cadigan Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila Development 129 2002 2565 2576
-
(2002)
Development
, vol.129
, pp. 2565-2576
-
-
Parker, D.S.1
Jemison, J.2
Cadigan, K.M.3
-
83
-
-
0036097733
-
A new nuclear component of the Wnt signalling pathway
-
B. Thompson, F. Townsley, R. Rosin-Arbesfeld, H. Musisi, and M. Bienz A new nuclear component of the Wnt signalling pathway Nat Cell Biol 4 2002 367 373
-
(2002)
Nat Cell Biol
, vol.4
, pp. 367-373
-
-
Thompson, B.1
Townsley, F.2
Rosin-Arbesfeld, R.3
Musisi, H.4
Bienz, M.5
-
84
-
-
1842430786
-
A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes
-
B.J. Thompson A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes Curr Biol 14 2004 458 466
-
(2004)
Curr Biol
, vol.14
, pp. 458-466
-
-
Thompson, B.J.1
-
85
-
-
4644290995
-
Identification and in vivo role of the Armadillo-Legless interaction
-
R. Hoffmans, and K. Basler Identification and in vivo role of the Armadillo-Legless interaction Development 131 2004 4393 4400 In this study, the Basler group re-examines the role of the Armadillo-Legless-Pygopus interaction in Drosophila embryogenesis. They characterize the Legless binding domain in Armadillo and show that it is separable from the LEF/TCF proteins, APC and E-cadherin binding sites.
-
(2004)
Development
, vol.131
, pp. 4393-4400
-
-
Hoffmans, R.1
Basler, K.2
-
86
-
-
3242706980
-
Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function
-
F.M. Townsley, A. Cliffe, and M. Bienz Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional co-activator function Nat Cell Biol 6 2004 626 633 In this study, the Bienz group addresses how Armadillo function is controlled by Legless and Pygopus, and demonstrates that Pygopus acts as nuclear anchor for Legless. Pygopus and Legless synergize to increase the transcriptional activity of β-catenin. Furthermore, the authors show that a fusion of Armadillo with a nuclear localization sequence is able to rescue Pygopus and Legless mutant fly embryos.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 626-633
-
-
Townsley, F.M.1
Cliffe, A.2
Bienz, M.3
-
87
-
-
1242317058
-
Pygopus residues required for its binding to Legless are critical for transcription and development
-
F.M. Townsley, B. Thompson, and M. Bienz Pygopus residues required for its binding to Legless are critical for transcription and development J Biol Chem 279 2004 5177 5183
-
(2004)
J Biol Chem
, vol.279
, pp. 5177-5183
-
-
Townsley, F.M.1
Thompson, B.2
Bienz, M.3
-
88
-
-
21844437361
-
Pygopus and legless provide essential transcriptional coactivator functions to armadillo/β-catenin
-
R. Hoffmans, R. Stadeli, and K. Basler Pygopus and legless provide essential transcriptional coactivator functions to armadillo/β-catenin Curr Biol 15 2005 1207 1211
-
(2005)
Curr Biol
, vol.15
, pp. 1207-1211
-
-
Hoffmans, R.1
Stadeli, R.2
Basler, K.3
-
89
-
-
26944436274
-
Dissecting nuclear Wingless signalling: Recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins
-
R. Stadeli, and K. Basler Dissecting nuclear Wingless signalling: Recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins Mech Dev 122 2005 1171 1182
-
(2005)
Mech Dev
, vol.122
, pp. 1171-1182
-
-
Stadeli, R.1
Basler, K.2
-
90
-
-
30644459430
-
BCL9-2, the homolog of BCL9/legless, is an essential component of the nuclear β-catenin/Lef-Tcf complex and acts in the Wnt signaling pathway in vivo
-
F.H. Brembeck, T. Schwarz-Romond, J. Bakkers, M. Hammerschmidt, and W. Birchmeier BCL9-2, the homolog of BCL9/legless, is an essential component of the nuclear β-catenin/Lef-Tcf complex and acts in the Wnt signaling pathway in vivo Workshop on Wnt Genes and Wnt Signalling, Instituto Juan March, Madrid (Spain) 151 2003 14
-
(2003)
Workshop on Wnt Genes and Wnt Signalling, Instituto Juan March, Madrid (Spain)
, vol.151
, pp. 14
-
-
Brembeck, F.H.1
Schwarz-Romond, T.2
Bakkers, J.3
Hammerschmidt, M.4
Birchmeier, W.5
-
91
-
-
0034523266
-
SUMO-nonclassical ubiquitin
-
F. Melchior SUMO-nonclassical ubiquitin Annu Rev Cell Dev Biol 16 2000 591 626
-
(2000)
Annu Rev Cell Dev Biol
, vol.16
, pp. 591-626
-
-
Melchior, F.1
-
92
-
-
0033792815
-
Maternally controlled β-catenin-mediated signaling is required for organizer formation in the zebrafish
-
C. Kelly, A.J. Chin, J.L. Leatherman, D.J. Kozlowski, and E.S. Weinberg Maternally controlled β-catenin-mediated signaling is required for organizer formation in the zebrafish Development 127 2000 3899 3911
-
(2000)
Development
, vol.127
, pp. 3899-3911
-
-
Kelly, C.1
Chin, A.J.2
Leatherman, J.L.3
Kozlowski, D.J.4
Weinberg, E.S.5
-
93
-
-
9244233875
-
Role of a BCL9-related β-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling
-
S. Adachi, T. Jigami, T. Yasui, T. Nakano, S. Ohwada, Y. Omori, S. Sugano, B. Ohkawara, H. Shibuya, T. Nakamura, and T. Akiyama Role of a BCL9-related β-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling Cancer Res 64 2004 8496 8501 This study shows that BCL9-2 (BCL9L) is an essential co-factor of β-catenin-dependent transcription. Overexpression of BCL9-2 induces malignant transformation of cells in vitro. The authors also report overexpression of BCL9-2 in a series of human colon cancer samples.
-
(2004)
Cancer Res
, vol.64
, pp. 8496-8501
-
-
Adachi, S.1
Jigami, T.2
Yasui, T.3
Nakano, T.4
Ohwada, S.5
Omori, Y.6
Sugano, S.7
Ohkawara, B.8
Shibuya, H.9
Nakamura, T.10
Akiyama, T.11
-
94
-
-
0035750347
-
Chromosome translocations: Dangerous liaisons revisited
-
J.D. Rowley Chromosome translocations: dangerous liaisons revisited Nat Rev Cancer 1 2001 245 250
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 245-250
-
-
Rowley, J.D.1
-
95
-
-
16844381831
-
Mechanisms of B-cell lymphoma pathogenesis
-
R. Kuppers Mechanisms of B-cell lymphoma pathogenesis Nat Rev Cancer 5 2005 251 262
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 251-262
-
-
Kuppers, R.1
-
96
-
-
0032520975
-
Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21
-
T.G. Willis, I.R. Zalcberg, L.J. Coignet, I. Wlodarska, M. Stul, D.M. Jadayel, C. Bastard, J.G. Treleaven, D. Catovsky, M.L. Silva, and M.J. Dyer Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21 Blood 91 1998 1873 1881
-
(1998)
Blood
, vol.91
, pp. 1873-1881
-
-
Willis, T.G.1
Zalcberg, I.R.2
Coignet, L.J.3
Wlodarska, I.4
Stul, M.5
Jadayel, D.M.6
Bastard, C.7
Treleaven, J.G.8
Catovsky, D.9
Silva, M.L.10
Dyer, M.J.11
-
97
-
-
0034797155
-
Novel evidence of a role for chromosome 1 pericentric heterochromatin in the pathogenesis of B-cell lymphoma and multiple myeloma
-
P. Le Baccon, D. Leroux, C. Dascalescu, S. Duley, D. Marais, E. Esmenjaud, J.J. Sotto, and M. Callanan Novel evidence of a role for chromosome 1 pericentric heterochromatin in the pathogenesis of B-cell lymphoma and multiple myeloma Genes Chromosomes Cancer 32 2001 250 264
-
(2001)
Genes Chromosomes Cancer
, vol.32
, pp. 250-264
-
-
Le Baccon, P.1
Leroux, D.2
Dascalescu, C.3
Duley, S.4
Marais, D.5
Esmenjaud, E.6
Sotto, J.J.7
Callanan, M.8
-
98
-
-
0036883556
-
Molecular cytogenetic analysis of genomic instability at the 1q12-22 chromosomal site in B-cell non-Hodgkin lymphoma
-
T. Itoyama, G. Nanjungud, W. Chen, V.G. Dyomin, J. Teruya-Feldstein, S.C. Jhanwar, A.D. Zelenetz, and R.S. Chaganti Molecular cytogenetic analysis of genomic instability at the 1q12-22 chromosomal site in B-cell non-Hodgkin lymphoma Genes Chromosomes Cancer 35 2002 318 328
-
(2002)
Genes Chromosomes Cancer
, vol.35
, pp. 318-328
-
-
Itoyama, T.1
Nanjungud, G.2
Chen, W.3
Dyomin, V.G.4
Teruya-Feldstein, J.5
Jhanwar, S.C.6
Zelenetz, A.D.7
Chaganti, R.S.8
-
99
-
-
0037376396
-
Characterization of the recurrent translocation t(1;1)(p36.3;q21.1-2) in non-Hodgkin lymphoma by multicolor banding and fluorescence in situ hybridization analysis
-
V.S. Lestou, O. Ludkovski, J.M. Connors, R.D. Gascoyne, W.L. Lam, and D.E. Horsman Characterization of the recurrent translocation t(1;1)(p36.3;q21.1-2) in non-Hodgkin lymphoma by multicolor banding and fluorescence in situ hybridization analysis Genes Chromosomes Cancer 36 2003 375 381
-
(2003)
Genes Chromosomes Cancer
, vol.36
, pp. 375-381
-
-
Lestou, V.S.1
Ludkovski, O.2
Connors, J.M.3
Gascoyne, R.D.4
Lam, W.L.5
Horsman, D.E.6
-
100
-
-
0027714648
-
Rearrangements involving chromosome band 11Q23 in acute leukaemia
-
J.D. Rowley Rearrangements involving chromosome band 11Q23 in acute leukaemia Semin Cancer Biol 4 1993 377 385
-
(1993)
Semin Cancer Biol
, vol.4
, pp. 377-385
-
-
Rowley, J.D.1
-
101
-
-
0033517349
-
Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas
-
C. Guo, P.S. White, M.J. Weiss, M.D. Hogarty, P.M. Thompson, D.O. Stram, R. Gerbing, K.K. Matthay, R.C. Seeger, G.M. Brodeur, and J.M. Maris Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas Oncogene 18 1999 4948 4957
-
(1999)
Oncogene
, vol.18
, pp. 4948-4957
-
-
Guo, C.1
White, P.S.2
Weiss, M.J.3
Hogarty, M.D.4
Thompson, P.M.5
Stram, D.O.6
Gerbing, R.7
Matthay, K.K.8
Seeger, R.C.9
Brodeur, G.M.10
Maris, J.M.11
-
102
-
-
0036175753
-
Incidence of chromosomal imbalances in advanced colorectal carcinomas and their metastases
-
T. Knosel, S. Petersen, H. Schwabe, K. Schluns, U. Stein, P.M. Schlag, M. Dietel, and I. Petersen Incidence of chromosomal imbalances in advanced colorectal carcinomas and their metastases Virchows Arch 440 2002 187 194
-
(2002)
Virchows Arch
, vol.440
, pp. 187-194
-
-
Knosel, T.1
Petersen, S.2
Schwabe, H.3
Schluns, K.4
Stein, U.5
Schlag, P.M.6
Dietel, M.7
Petersen, I.8
-
103
-
-
7244229604
-
Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes
-
C.J. Gottardi, and B.M. Gumbiner Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes J Cell Biol 167 2004 339 349 Gottardi and Gumbiner propose a model by which distinct molecular forms of β-catenin act either in adhesion or in Wnt signaling. Wnt signaling promotes the formation of a monomeric form of β-catenin that preferentially binds to LEF/TCF proteins but not to the cadherins. A distinct molecular form of β-catenin, consisting of β-catenin-α-catenin dimers, preferentially binds to cadherins.
-
(2004)
J Cell Biol
, vol.167
, pp. 339-349
-
-
Gottardi, C.J.1
Gumbiner, B.M.2
-
104
-
-
0032879856
-
β-catenin is a major tyrosine-phosphorylated protein during mouse oocyte maturation and preimplantation development
-
M. Ohsugi, S. Butz, and R. Kemler β-catenin is a major tyrosine-phosphorylated protein during mouse oocyte maturation and preimplantation development Dev Dyn 216 1999 168 176
-
(1999)
Dev Dyn
, vol.216
, pp. 168-176
-
-
Ohsugi, M.1
Butz, S.2
Kemler, R.3
-
105
-
-
0035834386
-
A phosphatase associated with metastasis of colorectal cancer
-
S. Saha, A. Bardelli, P. Buckhaults, V.E. Velculescu, C. Rago, B. St Croix, K.E. Romans, M.A. Choti, C. Lengauer, K.W. Kinzler, and B. Vogelstein A phosphatase associated with metastasis of colorectal cancer Science 294 2001 1343 1346
-
(2001)
Science
, vol.294
, pp. 1343-1346
-
-
Saha, S.1
Bardelli, A.2
Buckhaults, P.3
Velculescu, V.E.4
Rago, C.5
St Croix, B.6
Romans, K.E.7
Choti, M.A.8
Lengauer, C.9
Kinzler, K.W.10
Vogelstein, B.11
-
106
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
E.R. Fearon, and B. Vogelstein A genetic model for colorectal tumorigenesis Cell 61 1990 759 767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
|