-
1
-
-
16344376889
-
From sorting endosomes to exocytosis: Association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, During recycling
-
Ward, E. S.; Martinez, C.; Vaccaro, C.; Zhou, J.; Tang, Q.; Ober, R. J. From sorting endosomes to exocytosis: Association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, During recycling. Mol. Biol. Cell 2005, 16, 2028-2038.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2028-2038
-
-
Ward, E.S.1
Martinez, C.2
Vaccaro, C.3
Zhou, J.4
Tang, Q.5
Ober, R.J.6
-
2
-
-
1142298744
-
Human antibody-Fc receptor interactions illuminated by crystal structures
-
Woof, J. M.; Burton, D. R. Human antibody-Fc receptor interactions illuminated by crystal structures. Nat. Rev. Immunol. 2004, 4, 89-99.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 89-99
-
-
Woof, J.M.1
Burton, D.R.2
-
3
-
-
27144449009
-
Monoclonal antibody therapy of cancer
-
Adams, G. P.; Weiner, L. M. Monoclonal antibody therapy of cancer. Nat. Biotechnol. 2005, 23, 1147-1157.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1147-1157
-
-
Adams, G.P.1
Weiner, L.M.2
-
4
-
-
27144550160
-
Arming antibodies: Prospects and challenges for immunoconjugates
-
Wu, A. M.; Senter, P. D. Arming antibodies: Prospects and challenges for immunoconjugates. Nat. Biotechnol. 2005, 23, 1137-1146.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1137-1146
-
-
Wu, A.M.1
Senter, P.D.2
-
5
-
-
27144432842
-
Engineered antibody fragments and the rise of single domains
-
Holliger, P.; Hudson, P. J. Engineered antibody fragments and the rise of single domains. Nat. Biotechnol. 2005, 23, 1126-1136.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1126-1136
-
-
Holliger, P.1
Hudson, P.J.2
-
6
-
-
70449276523
-
The hydrolysis of rabbit y-globulin and antibodies with crystalline papain
-
Porter, R. R. The hydrolysis of rabbit y-globulin and antibodies with crystalline papain. Biochem. J. 1959, 73, 119-126.
-
(1959)
Biochem. J.
, vol.73
, pp. 119-126
-
-
Porter, R.R.1
-
7
-
-
0032146225
-
Recombinant antibody fragments
-
Hudson, P. J. Recombinant antibody fragments. Curr. Opin. Biotechnol. 1998, 9, 395-402.
-
(1998)
Curr. Opin. Biotechnol.
, vol.9
, pp. 395-402
-
-
Hudson, P.J.1
-
8
-
-
0033867593
-
Of mice and men: Hybridoma and recombinant antibodies
-
Little, M.; Kipriyanov, S. M.; le Gall, F.; Moldenhauer, G. Of mice and men: Hybridoma and recombinant antibodies. Immunol. Today 2000, 21, 364-370.
-
(2000)
Immunol. Today
, vol.21
, pp. 364-370
-
-
Little, M.1
Kipriyanov, S.M.2
le Gall, F.3
Moldenhauer, G.4
-
9
-
-
0024292736
-
Assembly of a functional immunoglobulin Fv fragment in Escherichia coli
-
Skerra, A.; Pluckthun, A. Assembly of a functional immunoglobulin Fv fragment in Escherichia coli. Science 1988, 240, 1038-1041.
-
(1988)
Science
, vol.240
, pp. 1038-1041
-
-
Skerra, A.1
Pluckthun, A.2
-
10
-
-
38649086154
-
Single chain Fab (scFab) fragment
-
Hust, M.; Jostock, T.; Menzel, C.; Voedisch, B.; Mohr, A.; Brenneis, M.; Kirsch, M. I.; Meier, D.; Dubel, S. Single chain Fab (scFab) fragment. BMC Biotechnol. 2007, 7, 14.
-
(2007)
BMC Biotechnol.
, vol.7
, pp. 14
-
-
Hust, M.1
Jostock, T.2
Menzel, C.3
Voedisch, B.4
Mohr, A.5
Brenneis, M.6
Kirsch, M.I.7
Meier, D.8
Dubel, S.9
-
11
-
-
78650151812
-
Enhancing the thermal stability of a single-chain Fv fragment by in vivo global fluorination of the proline residues
-
Edwardraja, S.; Sriram, S.; Govindan, R.; Budisa, N.; Lee, S. G. Enhancing the thermal stability of a single-chain Fv fragment by in vivo global fluorination of the proline residues. Mol. Biosyst. 2011, 7, 258-265.
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 258-265
-
-
Edwardraja, S.1
Sriram, S.2
Govindan, R.3
Budisa, N.4
Lee, S.G.5
-
12
-
-
77953653252
-
Antibody fragments: Hope and hype
-
Nelson, A. L. Antibody fragments: Hope and hype. MAbs 2010, 2, 77-83.
-
(2010)
MAbs
, vol.2
, pp. 77-83
-
-
Nelson, A.L.1
-
13
-
-
64349107630
-
Development trends for therapeutic antibody fragments
-
Nelson, A. L.; Reichert, J. M. Development trends for therapeutic antibody fragments. Nat. Biotechnol. 2009, 27, 331-337.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 331-337
-
-
Nelson, A.L.1
Reichert, J.M.2
-
15
-
-
0024293979
-
Single-chain antigen-binding proteins
-
Bird, R. E.; Hardman, K. D.; Jacobson, J. W.; Johnson, S.; Kaufman, B. M.; Lee, S. M.; Lee, T.; Pope, S. H.; Riordan, G. S.; Whitlow, M. Single-chain antigen-binding proteins. Science 1988, 242, 423-426.
-
(1988)
Science
, vol.242
, pp. 423-426
-
-
Bird, R.E.1
Hardman, K.D.2
Jacobson, J.W.3
Johnson, S.4
Kaufman, B.M.5
Lee, S.M.6
Lee, T.7
Pope, S.H.8
Riordan, G.S.9
Whitlow, M.10
-
16
-
-
0004198722
-
Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
-
Huston, J. S.; Levinson, D.; Mudgett-Hunter, M.; Tai, M. S.; Novotny, J.; Margolies, M. N.; Ridge, R. J.; Bruccoleri, R. E.; Haber, E.; Crea, R.; et al. Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 1988, 85, 5879-5883.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5879-5883
-
-
Huston, J.S.1
Levinson, D.2
Mudgett-Hunter, M.3
Tai, M.S.4
Novotny, J.5
Margolies, M.N.6
Ridge, R.J.7
Bruccoleri, R.E.8
Haber, E.9
Crea, R.10
-
17
-
-
84859715471
-
scFv antibody: Principles and clinical application
-
Ahmad, Z. A.; Yeap, S. K.; Ali, A. M.; Ho, W. Y.; Alitheen, N. B.; Hamid, M. scFv antibody: Principles and clinical application. Dev. Immunol. 2012, 2012, 980250.
-
(2012)
Dev. Immunol.
, vol.2012
, pp. 980250
-
-
Ahmad, Z.A.1
Yeap, S.K.2
Ali, A.M.3
Ho, W.Y.4
Alitheen, N.B.5
Hamid, M.6
-
18
-
-
0027332881
-
An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability
-
Whitlow, M.; Bell, B. A.; Feng, S. L.; Filpula, D.; Hardman, K. D.; Hubert, S. L.; Rollence, M. L.; Wood, J. F.; Schott, M. E.; Milenic, D. E.; et al. An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability. Protein Eng. 1993, 6, 989-995.
-
(1993)
Protein Eng.
, vol.6
, pp. 989-995
-
-
Whitlow, M.1
Bell, B.A.2
Feng, S.L.3
Filpula, D.4
Hardman, K.D.5
Hubert, S.L.6
Rollence, M.L.7
Wood, J.F.8
Schott, M.E.9
Milenic, D.E.10
-
19
-
-
0028846149
-
Properties of a single-chain antibody containing different linker peptides
-
Alfthan, K.; Takkinen, K.; Sizmann, D.; Soderlund, H.; Teeri, T. T. Properties of a single-chain antibody containing different linker peptides. Protein Eng. 1995, 8, 725-731.
-
(1995)
Protein Eng.
, vol.8
, pp. 725-731
-
-
Alfthan, K.1
Takkinen, K.2
Sizmann, D.3
Soderlund, H.4
Teeri, T.T.5
-
20
-
-
0032884573
-
Recombinant protein expression in Escherichia coli
-
Baneyx, F. Recombinant protein expression in Escherichia coli. Curr. Opin. Biotechnol. 1999, 10, 411-421.
-
(1999)
Curr. Opin. Biotechnol.
, vol.10
, pp. 411-421
-
-
Baneyx, F.1
-
21
-
-
33745464891
-
Isolation of anti-CD22 Fv with high affinity by Fv display on human cells
-
Ho, M.; Nagata, S.; Pastan, I. Isolation of anti-CD22 Fv with high affinity by Fv display on human cells. Proc. Natl. Acad. Sci. USA 2006, 103, 9637-9642.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9637-9642
-
-
Ho, M.1
Nagata, S.2
Pastan, I.3
-
22
-
-
33749597339
-
Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems
-
Galeffi, P.; Lombardi, A.; Pietraforte, I.; Novelli, F.; Di Donato, M.; Sperandei, M.; Tornambe, A.; Fraioli, R.; Martayan, A.; Natali, P. G.; et al. Functional expression of a single-chain antibody to ErbB-2 in plants and cell-free systems. J. Transl. Med. 2006, 4, 39.
-
(2006)
J. Transl. Med.
, vol.4
, pp. 39
-
-
Galeffi, P.1
Lombardi, A.2
Pietraforte, I.3
Novelli, F.4
Di Donato, M.5
Sperandei, M.6
Tornambe, A.7
Fraioli, R.8
Martayan, A.9
Natali, P.G.10
-
23
-
-
0036451715
-
Soluble expression of a functional recombinant cytolytic immunotoxin in insect cells
-
Choo, A. B.; Dunn, R. D.; Broady, K. W.; Raison, R. L. Soluble expression of a functional recombinant cytolytic immunotoxin in insect cells. Protein Expres. Purif. 2002, 24, 338-347.
-
(2002)
Protein Expres. Purif.
, vol.24
, pp. 338-347
-
-
Choo, A.B.1
Dunn, R.D.2
Broady, K.W.3
Raison, R.L.4
-
24
-
-
0031931487
-
Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity
-
Chowdhury, P. S.; Viner, J. L.; Beers, R.; Pastan, I. Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity. Proc. National. Acad. Sci. USA 1998, 95, 669-674.
-
(1998)
Proc. National. Acad. Sci. USA
, vol.95
, pp. 669-674
-
-
Chowdhury, P.S.1
Viner, J.L.2
Beers, R.3
Pastan, I.4
-
25
-
-
64249112661
-
Current constructs and targets in clinical development for antibody-based cancer therapy
-
Deckert, P. M. Current constructs and targets in clinical development for antibody-based cancer therapy. Curr. Drug Targets 2009, 10, 158-175.
-
(2009)
Curr. Drug Targets
, vol.10
, pp. 158-175
-
-
Deckert, P.M.1
-
26
-
-
85136046795
-
Radioiodinated-anti-TAG-72 covalently linked CC49 divalent single-chain Fv antibody
-
In; National Center for Biotechnology Information: Bethesda, MD, USA
-
Cheng, K. T. Radioiodinated-anti-TAG-72 covalently linked CC49 divalent single-chain Fv antibody. In Molecular Imaging and Contrast Agent Database (MICAD); National Center for Biotechnology Information: Bethesda, MD, USA, 2004.
-
(2004)
Molecular Imaging and Contrast Agent Database (MICAD)
-
-
Cheng, K.T.1
-
27
-
-
82555175818
-
Toward in vivo imaging of heart disease using a radiolabeled single-chain Fv fragment targeting tenascin-C
-
Kobayashi, N.; Odaka, K.; Uehara, T.; Imanaka-Yoshida, K.; Kato, Y.; Oyama, H.; Tadokoro, H.; Akizawa, H.; Tanada, S.; Hiroe, M.; et al. Toward in vivo imaging of heart disease using a radiolabeled single-chain Fv fragment targeting tenascin-C. Anal. Chem. 2011, 83, 9123-9130.
-
(2011)
Anal. Chem.
, vol.83
, pp. 9123-9130
-
-
Kobayashi, N.1
Odaka, K.2
Uehara, T.3
Imanaka-Yoshida, K.4
Kato, Y.5
Oyama, H.6
Tadokoro, H.7
Akizawa, H.8
Tanada, S.9
Hiroe, M.10
-
28
-
-
13944266719
-
Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody
-
Robinson, M. K.; Doss, M.; Shaller, C.; Narayanan, D.; Marks, J. D.; Adler, L. P.; Gonzalez Trotter, D. E.; Adams, G. P. Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody. Cancer Res. 2005, 65, 1471-1478.
-
(2005)
Cancer Res.
, vol.65
, pp. 1471-1478
-
-
Robinson, M.K.1
Doss, M.2
Shaller, C.3
Narayanan, D.4
Marks, J.D.5
Adler, L.P.6
Gonzalez Trotter, D.E.7
Adams, G.P.8
-
29
-
-
1542681650
-
124I-labeled engineered anti-CEAcea minibodies and diabodies allow high-contrast, antigen-specific small-animal PETimaging of xenografts in athymic mice
-
Sundaresan, G.; Yazaki, P. J.; Shively, J. E.; Finn, R. D.; Larson, S. M.; Raubitschek, A. A.; Williams, L. E.; Chatziioannou, A. F.; Gambhir, S. S.; Wu, A. M. 124I-labeled engineered anti-CEAcea minibodies and diabodies allow high-contrast, antigen-specific small-animal PETimaging of xenografts in athymic mice. J. Nucl. Med. 2003, 44, 1962-1969.
-
(2003)
J. Nucl. Med.
, vol.44
, pp. 1962-1969
-
-
Sundaresan, G.1
Yazaki, P.J.2
Shively, J.E.3
Finn, R.D.4
Larson, S.M.5
Raubitschek, A.A.6
Williams, L.E.7
Chatziioannou, A.F.8
Gambhir, S.S.9
Wu, A.M.10
-
30
-
-
0032489812
-
Targeted delivery of chemotherapeutics: Tumor-activated prodrug therapy
-
Chari, R. V. Targeted delivery of chemotherapeutics: Tumor-activated prodrug therapy. Adv. Drug Deliv. Rev. 1998, 31, 89-104.
-
(1998)
Adv. Drug Deliv. Rev.
, vol.31
, pp. 89-104
-
-
Chari, R.V.1
-
31
-
-
84858645667
-
A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma growth in vitro and in a murine transplantation model
-
Gattenlohner, S.; Jorissen, H.; Huhn, M.; Vincent, A.; Beeson, D.; Tzartos, S.; Mamalaki, A.; Etschmann, B.; Muller-Hermelink, H. K.; Koscielniak, E.; et al. A human recombinant autoantibody-based immunotoxin specific for the fetal acetylcholine receptor inhibits rhabdomyosarcoma growth in vitro and in a murine transplantation model. J. Biomed. Biotechnol. 2010, 2010, 187621.
-
(2010)
J. Biomed. Biotechnol.
, vol.2010
, pp. 187621
-
-
Gattenlohner, S.1
Jorissen, H.2
Huhn, M.3
Vincent, A.4
Beeson, D.5
Tzartos, S.6
Mamalaki, A.7
Etschmann, B.8
Muller-Hermelink, H.K.9
Koscielniak, E.10
-
32
-
-
77951687530
-
Construction and characterization of a novel fusion protein MG7-scFv/SEB against gastric cancer
-
Tong, Q.; Liu, K.; Lu, X. M.; Shu, X. G.; Wang, G. B. Construction and characterization of a novel fusion protein MG7-scFv/SEB against gastric cancer. J. Biomed. Biotechnol. 2010, 2010, 121094.
-
(2010)
J. Biomed. Biotechnol.
, vol.2010
, pp. 121094
-
-
Tong, Q.1
Liu, K.2
Lu, X.M.3
Shu, X.G.4
Wang, G.B.5
-
33
-
-
59649130081
-
Sustained in vivo inhibition of protein domains using single-chain Fv recombinant antibodies and its application to dissect rgma activity on axonal outgrowth
-
Tassew, N. G.; Charish, J.; Chestopalova, L.; Monnier, P. P. Sustained in vivo inhibition of protein domains using single-chain Fv recombinant antibodies and its application to dissect rgma activity on axonal outgrowth. J. Neurosci. 2009, 29, 1126-1131.
-
(2009)
J. Neurosci.
, vol.29
, pp. 1126-1131
-
-
Tassew, N.G.1
Charish, J.2
Chestopalova, L.3
Monnier, P.P.4
-
34
-
-
80054892346
-
Paracrine Pax6 activity regulates oligodendrocyte precursor cell migration in the chick embryonic neural tube
-
Di Lullo, E.; Haton, C.; Le Poupon, C.; Volovitch, M.; Joliot, A.; Thomas, J. L.; Prochiantz, A. Paracrine Pax6 activity regulates oligodendrocyte precursor cell migration in the chick embryonic neural tube. Development 2011, 138, 4991-5001.
-
(2011)
Development
, vol.138
, pp. 4991-5001
-
-
Di Lullo, E.1
Haton, C.2
Le Poupon, C.3
Volovitch, M.4
Joliot, A.5
Thomas, J.L.6
Prochiantz, A.7
-
35
-
-
34948878051
-
Vaccine immunotherapy in breast cancer treatment: Promising, but still early
-
Curigliano, G.; Spitaleri, G.; Dettori, M.; Locatelli, M.; Scarano, E.; Goldhirsch, A. Vaccine immunotherapy in breast cancer treatment: Promising, but still early. Expert Rev. Anticancer Ther. 2007, 7, 1225-1241.
-
(2007)
Expert Rev. Anticancer Ther.
, vol.7
, pp. 1225-1241
-
-
Curigliano, G.1
Spitaleri, G.2
Dettori, M.3
Locatelli, M.4
Scarano, E.5
Goldhirsch, A.6
-
36
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard, F.; Cannon, C.; Barbour, R.; Burke, R. L.; Games, D.; Grajeda, H.; Guido, T.; Hu, K.; Huang, J.; Johnson-Wood, K.; et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 2000, 6, 916-919.
-
(2000)
Nat. Med.
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
-
37
-
-
33751080719
-
Synthetic therapeutic antibodies
-
Sidhu, S. S.; Fellouse, F. A. Synthetic therapeutic antibodies. Nat. Chem. Biol. 2006, 2, 682-688.
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 682-688
-
-
Sidhu, S.S.1
Fellouse, F.A.2
-
38
-
-
79952399087
-
Beyond natural antibodies: The power of in vitro display technologies
-
Bradbury, A. R.; Sidhu, S.; Dubel, S.; McCafferty, J. Beyond natural antibodies: The power of in vitro display technologies. Nat. Biotechnol. 2011, 29, 245-254.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 245-254
-
-
Bradbury, A.R.1
Sidhu, S.2
Dubel, S.3
McCafferty, J.4
-
39
-
-
84860692601
-
Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteins
-
Butler, D. C.; McLear, J. A.; Messer, A. Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteins. Prog. Neurobiol. 2012, 97, 190-204.
-
(2012)
Prog. Neurobiol.
, vol.97
, pp. 190-204
-
-
Butler, D.C.1
McLear, J.A.2
Messer, A.3
-
40
-
-
50549104374
-
Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy
-
Zuber, C.; Mitteregger, G.; Schuhmann, N.; Rey, C.; Knackmuss, S.; Rupprecht, W.; Reusch, U.; Pace, C.; Little, M.; Kretzschmar, H. A.; et al. Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy. J. Gen. Virol. 2008, 89, 2055-2061.
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 2055-2061
-
-
Zuber, C.1
Mitteregger, G.2
Schuhmann, N.3
Rey, C.4
Knackmuss, S.5
Rupprecht, W.6
Reusch, U.7
Pace, C.8
Little, M.9
Kretzschmar, H.A.10
-
41
-
-
54249126862
-
Gene therapy using adeno-associated virus vectors
-
Daya, S.; Berns, K. I. Gene therapy using adeno-associated virus vectors. Clin. Microbiol. Rev. 2008, 21, 583-593.
-
(2008)
Clin. Microbiol. Rev.
, vol.21
, pp. 583-593
-
-
Daya, S.1
Berns, K.I.2
-
42
-
-
84866006613
-
Human anti-CCR4 minibody gene transfer for the treatment of cutaneous t-cell lymphoma
-
Han, T.; Abdel-Motal, U. M.; Chang, D. K.; Sui, J.; Muvaffak, A.; Campbell, J.; Zhu, Q.; Kupper, T. S.; Marasco, W. A. Human anti-CCR4 minibody gene transfer for the treatment of cutaneous t-cell lymphoma. PLoS One 2012, 7, e44455.
-
(2012)
PLoS One
, vol.7
-
-
Han, T.1
Abdel-Motal, U.M.2
Chang, D.K.3
Sui, J.4
Muvaffak, A.5
Campbell, J.6
Zhu, Q.7
Kupper, T.S.8
Marasco, W.A.9
-
43
-
-
0023265819
-
Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors
-
Hughes, S. H.; Greenhouse, J. J.; Petropoulos, C. J.; Sutrave, P. Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors. J. Virol. 1987, 61, 3004-3012.
-
(1987)
J. Virol.
, vol.61
, pp. 3004-3012
-
-
Hughes, S.H.1
Greenhouse, J.J.2
Petropoulos, C.J.3
Sutrave, P.4
-
44
-
-
79957452852
-
A therapeutic antibody targeting BACE1 inhibits amyloid-beta production in vivo
-
Atwal, J. K.; Chen, Y.; Chiu, C.; Mortensen, D. L.; Meilandt, W. J.; Liu, Y.; Heise, C. E.; Hoyte, K.; Luk, W.; Lu, Y.; et al. A therapeutic antibody targeting BACE1 inhibits amyloid-beta production in vivo. Sci. Transl. Med. 2011, 3, 84ra43.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Atwal, J.K.1
Chen, Y.2
Chiu, C.3
Mortensen, D.L.4
Meilandt, W.J.5
Liu, Y.6
Heise, C.E.7
Hoyte, K.8
Luk, W.9
Lu, Y.10
-
45
-
-
0036853548
-
Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease
-
Hock, C.; Konietzko, U.; Papassotiropoulos, A.; Wollmer, A.; Streffer, J.; von Rotz, R. C.; Davey, G.; Moritz, E.; Nitsch, R. M. Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease. Nat. Med. 2002, 8, 1270-1275.
-
(2002)
Nat. Med.
, vol.8
, pp. 1270-1275
-
-
Hock, C.1
Konietzko, U.2
Papassotiropoulos, A.3
Wollmer, A.4
Streffer, J.5
von Rotz, R.C.6
Davey, G.7
Moritz, E.8
Nitsch, R.M.9
-
46
-
-
76249087751
-
Pharmacokinetics and brain uptake of a genetically engineered bifunctional fusion antibody targeting the mouse transferrin receptor
-
Boado, R. J.; Zhou, Q. H.; Lu, J. Z.; Hui, E. K.; Pardridge, W. M. Pharmacokinetics and brain uptake of a genetically engineered bifunctional fusion antibody targeting the mouse transferrin receptor. Mol. Pharm. 2010, 7, 237-244.
-
(2010)
Mol. Pharm.
, vol.7
, pp. 237-244
-
-
Boado, R.J.1
Zhou, Q.H.2
Lu, J.Z.3
Hui, E.K.4
Pardridge, W.M.5
-
47
-
-
74849088013
-
IgG-single chain Fv fusion protein therapeutic for Alzheimer's disease: Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey
-
Boado, R. J.; Lu, J. Z.; Hui, E. K.; Pardridge, W. M. IgG-single chain Fv fusion protein therapeutic for Alzheimer's disease: Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey. Biotechnol. Bioeng. 2010, 105, 627-635.
-
(2010)
Biotechnol. Bioeng.
, vol.105
, pp. 627-635
-
-
Boado, R.J.1
Lu, J.Z.2
Hui, E.K.3
Pardridge, W.M.4
-
48
-
-
79957439772
-
Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target
-
Yu, Y. J.; Zhang, Y.; Kenrick, M.; Hoyte, K.; Luk, W.; Lu, Y.; Atwal, J.; Elliott, J. M.; Prabhu, S.; Watts, R. J. et al. Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target. Sci. Transl. Med. 2011, 3, 84ra44.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Yu, Y.J.1
Zhang, Y.2
Kenrick, M.3
Hoyte, K.4
Luk, W.5
Lu, Y.6
Atwal, J.7
Elliott, J.M.8
Prabhu, S.9
Watts, R.J.10
-
49
-
-
84873085590
-
Recombinant single-chain antibody with the Trojan peptide penetratin positioned in the linker region enables cargo transfer across the blood-brain barrier
-
Skrlj, N.; Drevensek, G.; Hudoklin, S.; Romih, R.; Curin Serbec, V.; Dolinar, M. Recombinant single-chain antibody with the Trojan peptide penetratin positioned in the linker region enables cargo transfer across the blood-brain barrier. Appl. Biochem. Biotechnol. 2013, 169, 159-169.
-
(2013)
Appl. Biochem. Biotechnol.
, vol.169
, pp. 159-169
-
-
Skrlj, N.1
Drevensek, G.2
Hudoklin, S.3
Romih, R.4
Curin Serbec, V.5
Dolinar, M.6
-
50
-
-
33746786005
-
Chemically modified short interfering hybrids (siHYBRIDS): Nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2
-
Hogrefe, R. I.; Lebedev, A. V.; Zon, G.; Pirollo, K. F.; Rait, A.; Zhou, Q.; Yu, W.; Chang, E. H. Chemically modified short interfering hybrids (siHYBRIDS): Nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2. Nucleos. Nucleot. Nucl. 2006, 25, 889-907.
-
(2006)
Nucleos. Nucleot. Nucl.
, vol.25
, pp. 889-907
-
-
Hogrefe, R.I.1
Lebedev, A.V.2
Zon, G.3
Pirollo, K.F.4
Rait, A.5
Zhou, Q.6
Yu, W.7
Chang, E.H.8
-
51
-
-
78049427830
-
Tumor antigen-targeted, monoclonal antibody-based immunotherapy: Clinical response, cellular immunity, and immunoescape
-
Ferris, R. L.; Jaffee, E. M.; Ferrone, S. Tumor antigen-targeted, monoclonal antibody-based immunotherapy: Clinical response, cellular immunity, and immunoescape. J. Clin. Oncol. 2010, 28, 4390-4399.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 4390-4399
-
-
Ferris, R.L.1
Jaffee, E.M.2
Ferrone, S.3
-
52
-
-
85136010217
-
Production and characterization of a CD25-specific scFv-Fc antibody secreted from Pichia pastoris
-
in press
-
Wan, L.; Zhu, S.; Zhu, J.; Yang, H.; Li, S.; Li, Y.; Cheng, J.; Lu, X. Production and characterization of a CD25-specific scFv-Fc antibody secreted from Pichia pastoris. Appl. Microbiol. Biotechnol. 2012, in press.
-
(2012)
Appl. Microbiol. Biotechnol.
-
-
Wan, L.1
Zhu, S.2
Zhu, J.3
Yang, H.4
Li, S.5
Li, Y.6
Cheng, J.7
Lu, X.8
-
53
-
-
10744227326
-
Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation
-
Yang, K.; Basu, A.; Wang, M.; Chintala, R.; Hsieh, M. C.; Liu, S.; Hua, J.; Zhang, Z.; Zhou, J.; Li, M.; et al. Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation. Protein Eng. 2003, 16, 761-770.
-
(2003)
Protein Eng.
, vol.16
, pp. 761-770
-
-
Yang, K.1
Basu, A.2
Wang, M.3
Chintala, R.4
Hsieh, M.C.5
Liu, S.6
Hua, J.7
Zhang, Z.8
Zhou, J.9
Li, M.10
-
54
-
-
0034682480
-
Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-TAC(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity
-
Tsutsumi, Y.; Onda, M.; Nagata, S.; Lee, B.; Kreitman, R. J.; Pastan, I. Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-TAC(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity. Proc. Natl. Acad. Sci. USA 2000, 97, 8548-8553.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8548-8553
-
-
Tsutsumi, Y.1
Onda, M.2
Nagata, S.3
Lee, B.4
Kreitman, R.J.5
Pastan, I.6
-
55
-
-
67650995905
-
Breast cancer lung metastasis requires expression of chemokine receptor CCR4 and regulatory T cells
-
Olkhanud, P. B.; Baatar, D.; Bodogai, M.; Hakim, F.; Gress, R.; Anderson, R. L.; Deng, J.; Xu, M.; Briest, S.; Biragyn, A. Breast cancer lung metastasis requires expression of chemokine receptor CCR4 and regulatory T cells. Cancer Res. 2009, 69, 5996-6004.
-
(2009)
Cancer Res.
, vol.69
, pp. 5996-6004
-
-
Olkhanud, P.B.1
Baatar, D.2
Bodogai, M.3
Hakim, F.4
Gress, R.5
Anderson, R.L.6
Deng, J.7
Xu, M.8
Briest, S.9
Biragyn, A.10
-
56
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel, T. J.; Coukos, G.; Zou, L.; Alvarez, X.; Cheng, P.; Mottram, P.; Evdemon-Hogan, M.; Conejo-Garcia, J. R.; Zhang, L.; Burow, M.; et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 2004, 10, 942-949.
-
(2004)
Nat. Med.
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
-
57
-
-
84863957822
-
Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes
-
Liu, W.; Onda, M.; Lee, B.; Kreitman, R. J.; Hassan, R.; Xiang, L.; Pastan, I. Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes. Proc. Natl. Acad. Sci. USA 2012, 109, 11782-11787.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 11782-11787
-
-
Liu, W.1
Onda, M.2
Lee, B.3
Kreitman, R.J.4
Hassan, R.5
Xiang, L.6
Pastan, I.7
-
58
-
-
84861542159
-
Phase i trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia
-
Kreitman, R. J.; Tallman, M. S.; Robak, T.; Coutre, S.; Wilson, W. H.; Stetler-Stevenson, M.; Fitzgerald, D. J.; Lechleider, R.; Pastan, I. Phase i trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia. J. Clin. Oncol. 2012, 30, 1822-1828.
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 1822-1828
-
-
Kreitman, R.J.1
Tallman, M.S.2
Robak, T.3
Coutre, S.4
Wilson, W.H.5
Stetler-Stevenson, M.6
Fitzgerald, D.J.7
Lechleider, R.8
Pastan, I.9
-
59
-
-
34548858453
-
Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus i. V. Infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers
-
Hassan, R.; Bullock, S.; Premkumar, A.; Kreitman, R. J.; Kindler, H.; Willingham, M. C.; Pastan, I. Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus i. V. Infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers. Clin. Cancer Res. 2007, 13, 5144-5149.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5144-5149
-
-
Hassan, R.1
Bullock, S.2
Premkumar, A.3
Kreitman, R.J.4
Kindler, H.5
Willingham, M.C.6
Pastan, I.7
-
60
-
-
84871599777
-
Immunotherapy strategies in the treatment of breast cancer
-
Soliman, H. Immunotherapy strategies in the treatment of breast cancer. Cancer Control 2013, 20, 17-21.
-
(2013)
Cancer Control
, vol.20
, pp. 17-21
-
-
Soliman, H.1
-
61
-
-
80052266213
-
The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics
-
Karran, E.; Mercken, M.; De Strooper, B. The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics. Nat. Rev. Drug Discov. 2011, 10, 698-712.
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 698-712
-
-
Karran, E.1
Mercken, M.2
De Strooper, B.3
-
62
-
-
77951782384
-
Current therapeutic targets for the treatment of Alzheimer's disease
-
Grill, J. D.; Cummings, J. L. Current therapeutic targets for the treatment of Alzheimer's disease. Expert Rev. Neurother. 2010, 10, 711-728.
-
(2010)
Expert Rev. Neurother.
, vol.10
, pp. 711-728
-
-
Grill, J.D.1
Cummings, J.L.2
-
63
-
-
0037203825
-
Nerve inflammation halts trial for Alzheimer's drug
-
Check, E. Nerve inflammation halts trial for Alzheimer's drug. Nature 2002, 415, 462.
-
(2002)
Nature
, vol.415
, pp. 462
-
-
Check, E.1
-
64
-
-
10744230547
-
Subacute meningoencephalitis in a subset of patients with AD after abeta42 immunization
-
Orgogozo, J. M.; Gilman, S.; Dartigues, J. F.; Laurent, B.; Puel, M.; Kirby, L. C.; Jouanny, P.; Dubois, B.; Eisner, L.; Flitman, S.; et al. Subacute meningoencephalitis in a subset of patients with AD after abeta42 immunization. Neurology 2003, 61, 46-54.
-
(2003)
Neurology
, vol.61
, pp. 46-54
-
-
Orgogozo, J.M.1
Gilman, S.2
Dartigues, J.F.3
Laurent, B.4
Puel, M.5
Kirby, L.C.6
Jouanny, P.7
Dubois, B.8
Eisner, L.9
Flitman, S.10
-
65
-
-
84865676982
-
Engineered antibody approaches for Alzheimer's disease immunotherapy
-
Robert, R.; Wark, K. L. Engineered antibody approaches for Alzheimer's disease immunotherapy. Arch. Biochem. Biophys. 2012, 526, 132-138.
-
(2012)
Arch. Biochem. Biophys.
, vol.526
, pp. 132-138
-
-
Robert, R.1
Wark, K.L.2
-
66
-
-
77957233161
-
Intramuscular delivery of a single chain antibody gene prevents brain abeta deposition and cognitive impairment in a mouse model of Alzheimer's disease
-
Wang, Y. J.; Gao, C. Y.; Yang, M.; Liu, X. H.; Sun, Y.; Pollard, A.; Dong, X. Y.; Wu, X. B.; Zhong, J. H.; Zhou, H. D.; et al. Intramuscular delivery of a single chain antibody gene prevents brain abeta deposition and cognitive impairment in a mouse model of Alzheimer's disease. Brain Behav. Immun. 2010, 24, 1281-1293.
-
(2010)
Brain Behav. Immun.
, vol.24
, pp. 1281-1293
-
-
Wang, Y.J.1
Gao, C.Y.2
Yang, M.3
Liu, X.H.4
Sun, Y.5
Pollard, A.6
Dong, X.Y.7
Wu, X.B.8
Zhong, J.H.9
Zhou, H.D.10
-
67
-
-
58549116371
-
Intramuscular delivery of a single chain antibody gene reduces brain abeta burden in a mouse model of Alzheimer's disease
-
Wang, Y. J.; Pollard, A.; Zhong, J. H.; Dong, X. Y.; Wu, X. B.; Zhou, H. D.; Zhou, X. F. Intramuscular delivery of a single chain antibody gene reduces brain abeta burden in a mouse model of Alzheimer's disease. Neurobiol. Aging 2009, 30, 364-376.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 364-376
-
-
Wang, Y.J.1
Pollard, A.2
Zhong, J.H.3
Dong, X.Y.4
Wu, X.B.5
Zhou, H.D.6
Zhou, X.F.7
-
68
-
-
33747178096
-
Anti-abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease
-
Fukuchi, K.; Tahara, K.; Kim, H. D.; Maxwell, J. A.; Lewis, T. L.; Accavitti-Loper, M. A.; Kim, H.; Ponnazhagan, S.; Lalonde, R. Anti-abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease. Neurobiol. Dis. 2006, 23, 502-511.
-
(2006)
Neurobiol. Dis.
, vol.23
, pp. 502-511
-
-
Fukuchi, K.1
Tahara, K.2
Kim, H.D.3
Maxwell, J.A.4
Lewis, T.L.5
Accavitti-Loper, M.A.6
Kim, H.7
Ponnazhagan, S.8
Lalonde, R.9
-
69
-
-
77955175395
-
Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice
-
Ryan, D. A.; Mastrangelo, M. A.; Narrow, W. C.; Sullivan, M. A.; Federoff, H. J.; Bowers, W. J. Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice. Mol. Ther. 2010, 18, 1471-1481.
-
(2010)
Mol. Ther.
, vol.18
, pp. 1471-1481
-
-
Ryan, D.A.1
Mastrangelo, M.A.2
Narrow, W.C.3
Sullivan, M.A.4
Federoff, H.J.5
Bowers, W.J.6
-
70
-
-
84875698008
-
Muscle-directed anti-abeta single-chain antibody delivery via AAV1 reduces cerebral abeta load in an Alzheimer's disease mouse model
-
Yang, J.; Pattanayak, A.; Song, M.; Kou, J.; Taguchi, H.; Paul, S.; Ponnazhagan, S.; Lalonde, R.; Fukuchi, K. Muscle-directed anti-abeta single-chain antibody delivery via AAV1 reduces cerebral abeta load in an Alzheimer's disease mouse model. J. Mol. Neurosci. 2013, 49, 277-288.
-
(2013)
J. Mol. Neurosci.
, vol.49
, pp. 277-288
-
-
Yang, J.1
Pattanayak, A.2
Song, M.3
Kou, J.4
Taguchi, H.5
Paul, S.6
Ponnazhagan, S.7
Lalonde, R.8
Fukuchi, K.9
-
71
-
-
79953699669
-
Chronic intranasal treatment with an antiabeta (30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease
-
Cattepoel, S.; Hanenberg, M.; Kulic, L.; Nitsch, R. M. Chronic intranasal treatment with an antiabeta (30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease. PLoS One 2011, 6, e18296.
-
(2011)
PLoS One
, vol.6
-
-
Cattepoel, S.1
Hanenberg, M.2
Kulic, L.3
Nitsch, R.M.4
-
72
-
-
79551655290
-
Huntington's disease: Can mice lead the way to treatment?
-
Crook, Z. R.; Housman, D. Huntington's disease: Can mice lead the way to treatment? Neuron 2011, 69, 423-435.
-
(2011)
Neuron
, vol.69
, pp. 423-435
-
-
Crook, Z.R.1
Housman, D.2
-
73
-
-
17544377783
-
A human single-chain v intrabody preferentially targets amino-terminal Huntingtin's fragments in striatal models of Huntington's disease
-
Miller, T. W.; Zhou, C.; Gines, S.; MacDonald, M. E.; Mazarakis, N. D.; Bates, G. P.; Huston, J. S.; Messer, A. A human single-chain v intrabody preferentially targets amino-terminal Huntingtin's fragments in striatal models of Huntington's disease. Neurobiol. Dis. 2005, 19, 47-56.
-
(2005)
Neurobiol. Dis.
, vol.19
, pp. 47-56
-
-
Miller, T.W.1
Zhou, C.2
Gines, S.3
McDonald, M.E.4
Mazarakis, N.D.5
Bates, G.P.6
Huston, J.S.7
Messer, A.8
-
74
-
-
84055182535
-
Bifunctional anti-huntingtin proteasome-directed intrabodies mediate efficient degradation of mutant huntingtin exon 1 protein fragments
-
Butler, D. C.; Messer, A. Bifunctional anti-huntingtin proteasome-directed intrabodies mediate efficient degradation of mutant huntingtin exon 1 protein fragments. PLoS One 2011, 6, e29199.
-
(2011)
PLoS One
, vol.6
-
-
Butler, D.C.1
Messer, A.2
-
75
-
-
77957930942
-
Early or late-stage anti-N-terminal huntingtin intrabody gene therapy reduces pathological features in B6. HDR6/1 mice
-
Snyder-Keller, A.; McLear, J. A.; Hathorn, T.; Messer, A. Early or late-stage anti-N-terminal huntingtin intrabody gene therapy reduces pathological features in B6. HDR6/1 mice. J. Neuropathol. Exp. Neurol. 2010, 69, 1078-1085.
-
(2010)
J. Neuropathol. Exp. Neurol.
, vol.69
, pp. 1078-1085
-
-
Snyder-Keller, A.1
McLear, J.A.2
Hathorn, T.3
Messer, A.4
-
76
-
-
44649113841
-
Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin
-
Wang, C. E.; Zhou, H.; McGuire, J. R.; Cerullo, V.; Lee, B.; Li, S. H.; Li, X. J. Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin. J. Cell Biol. 2008, 181, 803-816.
-
(2008)
J. Cell Biol.
, vol.181
, pp. 803-816
-
-
Wang, C.E.1
Zhou, H.2
McGuire, J.R.3
Cerullo, V.4
Lee, B.5
Li, S.H.6
Li, X.J.7
-
77
-
-
84868108817
-
Self-assembling complexes of quantum dots and scFv antibodies for cancer cell targeting and imaging
-
Zdobnova, T. A.; Stremovskiy, O. A.; Lebedenko, E. N.; Deyev, S. M. Self-assembling complexes of quantum dots and scFv antibodies for cancer cell targeting and imaging. PLoS One 2012, 7, e48248.
-
(2012)
PLoS One
, vol.7
-
-
Zdobnova, T.A.1
Stremovskiy, O.A.2
Lebedenko, E.N.3
Deyev, S.M.4
-
78
-
-
84862967037
-
Quantum dot-conjugated anti-GRP78 scFv inhibits cancer growth in mice
-
Xu, W.; Liu, L.; Brown, N. J.; Christian, S.; Hornby, D. Quantum dot-conjugated anti-GRP78 scFv inhibits cancer growth in mice. Molecules 2012, 17, 796-808.
-
(2012)
Molecules
, vol.17
, pp. 796-808
-
-
Xu, W.1
Liu, L.2
Brown, N.J.3
Christian, S.4
Hornby, D.5
-
79
-
-
34248571826
-
GRP78 induction in cancer: Therapeutic and prognostic implications
-
Lee, A. S. GRP78 induction in cancer: Therapeutic and prognostic implications. Cancer Res. 2007, 67, 3496-3499.
-
(2007)
Cancer Res.
, vol.67
, pp. 3496-3499
-
-
Lee, A.S.1
-
80
-
-
72149123166
-
Nanoparticles functionalized with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells
-
Vigor, K. L.; Kyrtatos, P. G.; Minogue, S.; Al-Jamal, K. T.; Kogelberg, H.; Tolner, B.; Kostarelos, K.; Begent, R. H.; Pankhurst, Q. A.; Lythgoe, M. F.; et al. Nanoparticles functionalized with recombinant single chain Fv antibody fragments (scFv) for the magnetic resonance imaging of cancer cells. Biomaterials 2010, 31, 1307-1315.
-
(2010)
Biomaterials
, vol.31
, pp. 1307-1315
-
-
Vigor, K.L.1
Kyrtatos, P.G.2
Minogue, S.3
Al-Jamal, K.T.4
Kogelberg, H.5
Tolner, B.6
Kostarelos, K.7
Begent, R.H.8
Pankhurst, Q.A.9
Lythgoe, M.F.10
-
81
-
-
77949881963
-
Antibody vectors for imaging
-
Olafsen, T.; Wu, A. M. Antibody vectors for imaging. Semin. Nucl. Med. 2010, 40, 167-181.
-
(2010)
Semin. Nucl. Med.
, vol.40
, pp. 167-181
-
-
Olafsen, T.1
Wu, A.M.2
-
82
-
-
49549117077
-
T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice
-
Kumar, P.; Ban, H. S.; Kim, S. S.; Wu, H.; Pearson, T.; Greiner, D. L.; Laouar, A.; Yao, J.; Haridas, V.; Habiro, K.; et al. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell 2008, 134, 577-586.
-
(2008)
Cell
, vol.134
, pp. 577-586
-
-
Kumar, P.1
Ban, H.S.2
Kim, S.S.3
Wu, H.4
Pearson, T.5
Greiner, D.L.6
Laouar, A.7
Yao, J.8
Haridas, V.9
Habiro, K.10
-
83
-
-
84864479534
-
The antibody-based delivery of interleukin-12 to the tumor neovasculature eradicates murine models of cancer in combination with paclitaxel
-
Pasche, N.; Wulhfard, S.; Pretto, F.; Carugati, E.; Neri, D. The antibody-based delivery of interleukin-12 to the tumor neovasculature eradicates murine models of cancer in combination with paclitaxel. Clin. Cancer Res. 2012, 18, 4092-4103.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 4092-4103
-
-
Pasche, N.1
Wulhfard, S.2
Pretto, F.3
Carugati, E.4
Neri, D.5
-
84
-
-
84861216409
-
Single chain variable fragment CD7 antibody conjugated PLGA/HDAC inhibitor immuno-nanoparticles: Developing human T cell-specific nano-technology for delivery of therapeutic drugs targeting latent HIV
-
Choi, S.; Lee, J.; Kumar, P.; Lee, K. Y.; Lee, S. K. Single chain variable fragment CD7 antibody conjugated PLGA/HDAC inhibitor immuno-nanoparticles: Developing human T cell-specific nano-technology for delivery of therapeutic drugs targeting latent HIV. J. Control Release 2011, 152 (Suppl 1), e9-e10.
-
(2011)
J. Control Release
, vol.152
, Issue.SUPPL. 1
-
-
Choi, S.1
Lee, J.2
Kumar, P.3
Lee, K.Y.4
Lee, S.K.5
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