Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy

Journal of General Virology

Volumn 89, Issue 8, 2008, Pages 2055-2061

  Zuber, Chantal ^a   Mitteregger, Gerda ^a   Schuhmann, Natascha ^b   Rey, Clémence ^a   Knackmuss, Stefan ^c   Rupprecht, Wolfgang ^a   Reusch, Uwe ^c   Pace, Claudia ^a   Little, Melvyn ^c   Kretzschmar, Hans A ^a   Hallek, Michael ^b   Büning, Hildegard ^b   Weiss, Stefan ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c Affimed GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LAMININ RECEPTOR; PARVOVIRUS VECTOR; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; ANTIBODY; IMMUNOGLOBULIN FC FRAGMENT; PRION PROTEIN;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DRUG TARGETING; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; HIPPOCAMPUS; IN VIVO STUDY; INCUBATION TIME; INOCULATION; MICROINJECTION; MOUSE; NONHUMAN; PRION; PRION DISEASE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SCRAPIE; SEROTYPE; SPLEEN; STEREOTACTIC PROCEDURE; VIRUS RECOMBINANT; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; GENE TRANSFER; GENE VECTOR; GENETIC RECOMBINATION; GENETICS; IMMUNOLOGY; METABOLISM; METHODOLOGY; VIROLOGY;

ADENO-ASSOCIATED VIRUS; MUS;

ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; DEPENDOVIRUS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HIPPOCAMPUS; IMMUNOGLOBULIN FC FRAGMENTS; MICE; MICE, INBRED C57BL; PRION DISEASES; PRPSC PROTEINS; RECEPTORS, LAMININ; RECOMBINATION, GENETIC; SPLEEN; TRANSDUCTION, GENETIC;

EID: 50549104374     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.83670-0     Document Type: Article

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