Regulation of satellite cell function in sarcopenia

Frontiers in Aging Neuroscience

Volumn 6, Issue SEP, 2014, Pages

  Alway, Stephen E ^a,b,c   Myers, Matthew J ^a   Mohamed, Junaith S ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b West Virginia Clinical and Translational Science Institute   (United States)

^c Center for Cardiovascular and Respiratory Sciences   (United States)

Author keywords

Aging; Apoptosis; Disuse atrophy; Injury; Oxidative stress; Rehabilitation

Indexed keywords

BETA HYDROXY BETA METHYLBUTYRIC ACID; BUTYRIC ACID DERIVATIVE; CATECHIN; EPIGALLOCATECHIN GALLATE; GREEN TEA EXTRACT; MUSCLE PROTEIN; NUTRACEUTICAL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; RESVERATROL; SIRTUIN 1; SOMATOMEDIN C; SUPEROXIDE; UNCLASSIFIED DRUG;

AGED; AGING; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CALORIC RESTRICTION; CELL AGING; CELL DIFFERENTIATION; CELL FUNCTION; CYTOLOGY; HUMAN; IMMOBILIZATION; INFLAMMATION; METABOLIC REGULATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MUSCLE ATROPHY; MUSCLE DENERVATION; MUSCLE EXERCISE; MUSCLE HYPERTROPHY; MUSCLE MASS; MUSCLE MITOCHONDRION; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; OXIDATIVE STRESS; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SARCOPENIA; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SKELETAL MUSCLE SATELLITE CELL; TEA;

EID: 84907942844     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2014.00246     Document Type: Article

References (213)

1. Adhihetty PJ, O'Leary MF, Hood DA Mitochondria in skeletal muscle: adaptable rheostats of apoptotic susceptibility. Exerc Sport Sci Rev 36: 116-121. 2008
2. Adhihetty PJ, Uguccioni G, Leick L, Hidalgo J, Pilegaard H, Hood DA (2009). The role of PGC-1{alpha} on mitochondrial function and apoptotic susceptibility in muscle. Am J Physiol Cell Physiol
3. Allen DL, Linderman JK, Roy RR, Bigbee AJ, Grindeland RE, Mukku V, Edgerton VR (1997). Apoptosis: a mechanism contributing to remodeling of skeletal muscle in response to hindlimb unweighting. Am J Physiol 273: C579-C587.
4. Allen RG & Tresini M (2000). Oxidative stress and gene regulation. Free Radic Biol Med 28 463-499.
5. Alway SE, Bennett BT, Wilson JC, Edens NK, Pereira SL (2014a). Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats. Exp Gerontol (50): 82-94.
6. Alway SE, Bennett BT, Wilson JC, Sperringer J, Mohamed JS, Edens NK, Pereira SL (2014b). Green tea extract attenuates muscle loss and improves muscle function during reloading after hindlimb suspension in aged rodents. J App Physiol
7. Alway SE, Degens H, Lowe DA, Krishnamurthy G (2002). Increased myogenic repressor Id mRNA and protein levels in hindlimb muscles of aged rats. Am J Physiol Regul Integr Comp Physiol (282): R411-R422.
8. Alway SE, Martyn JK, Ouyang J, Chaudhrai A, Murlasits ZS (2003). Id2 expression during apoptosis and satellite cell activation in unloaded and loaded quail skeletal muscles. Am J Physiol Regul Integr Comp Physiol (284): R540-R549.
9. Alway SE, Morissette MR, & Siu PM (2011). Aging and apoptosis in muscle. In Handbook of the Biology of Aging, eds. Masoro EJ & Austad S, pp. 64-139. Elsevier, Amsterdam • Boston • Heidelberg • London • New York • Oxford • Paris • San Diego • San Francisco • Singapore • Sydney • Tokyo.
10. Alway SE, Pereira SL, Edens NK, Hao Y, Bennett BT (2013). β-Hydroxy-β-methylbutyrate (HMB) enhances the proliferation of satellite cells in fast muscles of aged rats during recovery from disuse atrophy. Exp Gerontol (48): 973-984.
11. Alway SE & Siu PM (2008)Nuclear Apoptosis Contributes to Sarcopenia. Exerc Sport Sci Rev (36): 51-57.
12. Alway SE, Siu PM, Murlasits Z, Butler DC (2005). Muscle hypertrophy models: applications for research on aging. Can J Appl Physiol (30): 591-624.
13. Andrade JP & Assuncao M (2012). Protective effects of chronic green tea consumption on agerelated neurodegeneration. Curr Pharm Des (18): 4-14.
14. Andrianjafiniony T, Dupre-Aucouturier S, Letexier D, Couchoux H, Desplanches D (2010). Oxidative stress, apoptosis, and proteolysis in skeletal muscle repair after unloading. Am J Physiol Cell Physiol (299): C307-C315.
15. Angione AR, Jiang C, Pan D, Wang YX, Kuang S (2011). PPARdelta regulates satellite cell proliferation and skeletal muscle regeneration. Skelet Muscle (1): 33.
16. Armand AS, Laziz I, Djeghloul D, Lecolle S, Bertrand AT, Biondi O, De Windt LJ, Chanoine C (2011). Apoptosis-inducing factor regulates skeletal muscle progenitor cell number and muscle phenotype. PLoS One (6): e27283.
17. Aversa Z, Bonetto A, Costelli P, Minero VG, Penna F, Baccino FM, Lucia S, Rossi FF, Muscaritoli M (2011). beta-hydroxy-beta-methylbutyrate (HMB) attenuates muscle and body weight loss in experimental cancer cachexia. Int J Oncol (38): 713-720.
18. Barberi L, Scicchitano BM, De RM, Bigot A, Duguez S, Wielgosik A, Stewart C, McPhee J, Conte M, Narici M, Franceschi C, Mouly V, Butler-Browne G, Musaro A (2013). Agedependent alteration in muscle regeneration: the critical role of tissue niche. Biogerontology (14): 273-292.
19. Beccafico S, Puglielli C, Pietrangelo T, Bellomo R, Fano G, Fulle S (2007). Age-dependent effects on functional aspects in human satellite cells. Ann N Y Acad Sci (1100): 345-352.
20. Bennett BT, Mohamed JS, Alway SE (2013). Effects of resveratrol on the recovery of muscle mass following disuse in the plantaris muscle of aged rats. PLoS One (8): e83518.
21. Bentzinger CF, Wang YX, Dumont NA, Rudnicki MA (2013). Cellular dynamics in the muscle satellite cell niche. EMBO Rep (14): 1062-1072.
22. Bernet JD, Doles JD, Hall JK, Kelly TK, Carter TA, Olwin BB (2014). p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice. Nat Med (20): 265-271.
23. Bortoli S, Renault V, Mariage-Samson R, Eveno E, Auffray C, Butler-Browne G, Pietu G (2005). Modifications in the myogenic program induced by in vivo and in vitro aging. Gene (347): 65-72.
24. Brack AS, Bildsoe H, Hughes SM (2005). Evidence that satellite cell decrement contributes to preferential decline in nuclear number from large fibres during murine age-related muscle atrophy. J Cell Sci (118): 4813-4821.
25. Brooks NE, Cadena SM, Vannier E, Cloutier G, Carambula S, Myburgh KH, RoubenoffR, Castaneda-Sceppa C (2010). Effects of resistance exercise combined with essential amino acid supplementation and energy deficit on markers of skeletal muscle atrophy and regeneration during bed rest and active recovery. Muscle Nerve (42): 927-935.
26. Buckingham M & Relaix F (2007). The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions. Annu Rev Cell Dev Biol(23): 645-673.
27. Burgos PR (2012). Therapeutic approach to malnutrition and sarcopenia. Nestle Nutr Inst Workshop Ser (72): 85-99.
28. Calvani R, Joseph AM, Adhihetty PJ, Miccheli A, Bossola M, Leeuwenburgh C, Bernabei R, Marzetti E (2013). Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy. Biol Chem (394): 393-414.
29. Carson JA & Alway SE (1996). Stretch overload-induced satellite cell activation in slow tonic muscle from adult and aged Japanese quail. Am J Physiol (270): C578-C584.
30. Carson JA, Yamaguchi M, Alway SE (1995). Hypertrophy and proliferation of skeletal muscle fibers from aged quail. J Appl Physiol (78): 293-299.
31. Casanova E, Baselga-Escudero L, Ribas-Latre A, Arola-Arnal A, Blade C, Arola L, Salvado MJ (2014). Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes. Biochim Biophys Acta (1837): 783-791.
32. Cerletti M, Jang YC, Finley LW, Haigis MC, Wagers AJ (2012). Short-term calorie restriction enhances skeletal muscle stem cell function. Cell Stem Cell (10): 515-519.
33. Chabi B, Ljubicic V, Menzies KJ, Huang JH, Saleem A, Hood DA (2008). Mitochondrial function and apoptotic susceptibility in aging skeletal muscle. Aging Cell (7): 2-12.
34. Chakkalakal J & Brack A (2012). Extrinsic Regulation of Satellite Cell Function and Muscle Regeneration Capacity during Aging. J Stem Cell Res Ther (Suppl 11): 001.
35. Chakkalakal JV, Jones KM, Basson MA, Brack AS (2012). The aged niche disrupts muscle stem cell quiescence. Nature (490): 355-360.
36. Chen CJ, Yu W, Fu YC, Wang X, Li JL, Wang W (2009). Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. Biochem Biophys Res Commun (378): 389-393.
37. Christov C, Chretien F, Abou-Khalil R, Bassez G, Vallet G, Authier FJ, Bassaglia Y, Shinin V, Tajbakhsh S, Chazaud B, Gherardi RK (2007). Muscle satellite cells and endothelial cells: close neighbors and privileged partners. Mol Biol Cell (18): 1397-1409.
38. Churchward-Venne TA, Breen L, Phillips SM (2014). Alterations in human muscle protein metabolism with aging: Protein and exercise as countermeasures to offset sarcopenia. Biofactors (40): 199-205.
39. Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de CR, Sinclair DA (2004). Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science (305): 390-392.
40. Collins CA, Olsen I, Zammit PS, Heslop L, Petrie A, Partridge TA, Morgan JE (2005). Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche. Cell (122): 289-301.
41. Collins CA, Zammit PS, Ruiz AP, Morgan JE, Partridge TA (2007). A population of myogenic stem cells that survives skeletal muscle aging. Stem Cells (25): 885-894.
42. Collins-Hooper H, Woolley TE, Dyson L, Patel A, Potter P, Baker RE, Gaffney EA, Maini PK, Dash PR, Patel K (2012). Age-related changes in speed and mechanism of adult skeletal muscle stem cell migration. Stem Cells (30): 1182-1195.
43. Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA (2005). Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature (433): 760-764.
44. Conboy IM & Rando TA (2005). Aging, stem cells and tissue regeneration: lessons from muscle. Cell Cycle (4): 407-410.
45. Cornelison DD & Wold BJ (1997). Single-cell analysis of regulatory gene expression in quiescent and activated mouse skeletal muscle satellite cells. Dev Biol (191): 270-283.
46. Cosgrove BD, Sacco A, Gilbert PM, Blau HM (2009). A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches. Differentiation (78): 185-194.
47. Cousin W, Ho ML, Desai R, Tham A, Chen RY, Kung S, Elabd C, Conboy IM (2013). Regenerative capacity of old muscle stem cells declines without significant accumulation of DNA damage. PLoS One (8): e63528.
48. Cutlip RG, Baker BA, Geronilla KB, Mercer RR, Kashon ML, Miller GR, Murlasits Z, Alway SE (2006). Chronic exposure to stretch-shortening contractions results in skeletal muscle adaptation in young rats and maladaptation in old rats. Appl Physiol Nutr Metab (31): 573-587.
49. Day K, Shefer G, Richardson JB, Enikolopov G, Yablonka-Reuveni Z (2007). Nestin-GFP reporter expression defines the quiescent state of skeletal muscle satellite cells. Dev Biol (304): 246-259.
50. Day K, Shefer G, Shearer A, Yablonka-Reuveni Z (2010). The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny. Dev Biol (340): 330-343.
51. Degens H (2010). The role of systemic inflammation in age-related muscle weakness and wasting. Scand J Med Sci Sports (20): 28-38.
52. Deschenes MR, Gaertner JR, O'Reilly S (2013). The effects of sarcopenia on muscles with different recruitment patterns and myofiber profiles. Curr Aging Sci (6): 266-272.
53. Dickinson JM, Volpi E, Rasmussen BB (2013). Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle. Exerc Sport Sci Rev (41): 216-223.
54. Drey M, Grosch C, Neuwirth C, Bauer JM, Sieber CC (2013). The Motor Unit Number Index (MUNIX) in sarcopenic patients. Exp Gerontol (48): 381-384.
55. Dreyer HC, Blanco CE, Sattler FR, Schroeder ET, Wiswell RA (2006). Satellite cell numbers in young and older men 24 hours after eccentric exercise. Muscle Nerve (33): 242-253.
56. Duguez S, Feasson L, Denis C, Freyssenet D (2002). Mitochondrial biogenesis during skeletal muscle regeneration. Am J Physiol Endocrinol Metab (282): E802-E809.
57. Dupont-Versteegden EE (2005). Apoptosis in muscle atrophy: relevance to sarcopenia. Exp Gerontol (40): 473-481.
58. Dupont-Versteegden EE, Strotman BA, Gurley CM, Gaddy D, Knox M, Fluckey JD, Peterson CA (2006). Nuclear translocation of EndoG at the initiation of disuse muscle atrophy and apoptosis is specific to myonuclei. Am J Physiol Regul Integr Comp Physiol (291): R1730-R1740.
59. Durbin SM, Jackson JR, Ryan MJ, Gigliotti JC, Alway SE, Tou JC (2014). Resveratrol supplementation preserves long bone mass, microstructure, and strength in hindlimb-suspended old male rats. J Bone Miner Metab (32): 38-47.
60. Dutta C, Hadley EC, Lexell J (1997). Sarcopenia and physical performance in old age: overview. Muscle Nerve Suppl (5): S5-S9.
61. Evans WJ (1995). What is sarcopenia? J Gerontol A Biol Sci Med Sci (50 Spec No): 5-8.
62. Faulkner JA, Brooks SV, Zerba E (1995). Muscle atrophy and weakness with aging: contractioninduced injury as an underlying mechanism. J Gerontol A Biol Sci Med Sci (50 Spec No): 124-129.
63. Frey RS, Gao X, Javaid K, Siddiqui SS, Rahman A, Malik AB (2006). Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells. J Biol Chem (281): 16128-16138.
64. Frey RS, Ushio-Fukai M, Malik AB (2009). NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal (11): 791-810.
65. Fry CS, Lee JD, Jackson JR, Kirby TJ, Stasko SA, Liu H, Dupont-Versteegden EE, McCarthy JJ, Peterson CA (2014). Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy. FASEB J (28): 1654-1665.
66. Fujimaki S, Hidaka R, Asashima M, Takemasa T, Kuwabara T (2014). Wnt protein-mediated satellite cell conversion in adult and aged mice following voluntary wheel running. J Biol Chem (289): 7399-7412.
67. Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA, Sartorelli V (2008). Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPKmediated regulation of Nampt. Dev Cell (14): 661-673.
68. Fulco M, Schiltz RL, Iezzi S, King MT, Zhao P, Kashiwaya Y, Hoffman E, Veech RL, Sartorelli V (2003). Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol Cell (12): 51-62.
69. Fulle S, Centurione L, Mancinelli R, Sancilio S, Manzoli FA, Di PR (2012). Stem cell ageing and apoptosis. Curr Pharm Des (18): 1694-1717.
70. Fulle S, Di DS, Puglielli C, Pietrangelo T, Beccafico S, Bellomo R, Protasi F, Fano G (2005). Age-dependent imbalance of the antioxidative system in human satellite cells. Exp Gerontol (40): 189-197.
71. Fulle S, Sancilio S, Mancinelli R, Gatta V, Di PR (2013). Dual role of the caspase enzymes in satellite cells from aged and young subjects. Cell Death Dis (4): e955.
72. Galuppo M, Di PR, Mazzon E, Genovese T, Crisafulli C, Paterniti I, Cuzzocrea E, Bramanti P, Kapoor A, Thiemermann C, Cuzzocrea S (2010). Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study. J Inflamm (Lond) (7): 12.
73. Garcia-Prat L, Sousa-Victor P, Munoz-Canoves P (2013). Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells. FEBS J (280): 4051-4062.
74. Ghosh S, Lertwattanarak R, Garduno JD, Galeana JJ, Li J, Zamarripa F, Lancaster JL, Mohan S, Hussey S, Musi N (2014). Elevated Muscle TLR4 Expression and Metabolic Endotoxemia in Human Aging. J Gerontol A Biol Sci Med Sci.
75. Gilbert PM, Corbel S, Doyonnas R, Havenstrite K, Magnusson KE, Blau HM (2012). A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. Integr Biol (Camb) (4): 360-367.
76. Gutierrez-Salmean G, Ciaraldi TP, Nogueira L, Barboza J, Taub PR, Hogan MC, Henry RR, Meaney E, Villarreal F, Ceballos G, Ramirez-Sanchez I (2014). Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J Nutr Biochem (25): 91-94.
77. Halevy O, Geyra A, Barak M, Uni Z, Sklan D (2000). Early posthatch starvation decreases satellite cell proliferation and skeletal muscle growth in chicks. J Nutr (130): 858-864.
78. Halevy O, Nadel Y, Barak M, Rozenboim I, Sklan D (2003). Early posthatch feeding stimulates satellite cell proliferation and skeletal muscle growth in turkey poults. J Nutr (133): 1376-1382.
79. Hao Y, Jackson JR, Wang Y, Edens N, Pereira SL, Alway SE (2011). ß-Hydroxy-ßmethylbutyrate reduces myonuclear apoptosis during recovery from hind limb suspensioninduced muscle fiber atrophy in aged rats. Am J Physiol Regul Integr Comp Physiol (301): R701-R715.
80. Haramizu S, Ota N, Hase T, Murase T (2011). Catechins attenuate eccentric exercise-induced inflammation and loss of force production in muscle in senescence-accelerated mice. J Appl Physiol (111): 1654-1663.
81. Haramizu S, Ota N, Hase T, Murase T (2013). Catechins supress muscle inflammation and hasten performance recovery after exercise. Med Sci Sports Exerc (45): 1694-1702.
82. Harridge SD (2003). Ageing and local growth factors in muscle. Scand J Med Sci Sports (13): 34-39.
83. Harthan LB, McFarland DC, Velleman SG (2013). The effect of syndecan-4 and glypican-1 expression on age-related changes in myogenic satellite cell proliferation, differentiation, and fibroblast growth factor 2 responsiveness. Comp Biochem Physiol A Mol Integr Physiol (166): 590-602.
84. Harthan LB, McFarland DC, Velleman SG (2014). The effect of nutritional status and myogenic satellite cell age on turkey satellite cell proliferation, differentiation, and expression of myogenic transcriptional regulatory factors and heparan sulfate proteoglycans syndecan-4 and glypican-1. Poult Sci (93): 174-186.
85. Hiona A & Leeuwenburgh C (2008). The role of mitochondrial DNA mutations in aging and sarcopenia: implications for the mitochondrial vicious cycle theory of aging. Exp Gerontol (43): 24-33.
86. Holecek M, Muthny T, Kovarik M, Sispera L (2009). Effect of beta-hydroxy-betamethylbutyrate (HMB) on protein metabolism in whole body and in selected tissues. Food Chem Toxicol (47): 255-259.
87. Jackson JR, Mula J, Kirby TJ, Fry CS, Lee JD, Ubele MF, Campbell KS, McCarthy JJ, Peterson CA, Dupont-Versteegden EE (2012). Satellite cell depletion does not inhibit adult skeletal muscle regrowth following unloading-induced atrophy. Am J Physiol Cell Physiol (303): C854-C861.
88. Jackson JR, Ryan MJ, Alway SE (2011). Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice. J Gerontol A Biol Sci Med Sci (66): 751-764.
89. Jackson JR, Ryan MJ, Hao Y, Alway SE (2010). Mediation of endogenous antioxidant enzymes and apoptotic signaling by resveratrol following muscle disuse in the gastrocnemius muscles of young and old rats. Am J Physiol Regul Integr Comp Physiol (299): R1572-R1581.
90. Jang YC, Sinha M, Cerletti M, Dall'Osso C, Wagers AJ (2011). Skeletal muscle stem cells: effects of aging and metabolism on muscle regenerative function. Cold Spring Harb Symp Quant Biol (76): 101-111.
91. Jash S & Adhya S (2012). Induction of muscle regeneration by RNA-mediated mitochondrial restoration. FASEB J (26): 4187-4197.
92. Joanisse S, Gillen JB, Bellamy LM, McKay BR, Tarnopolsky MA, Gibala MJ, Parise G (2013). Evidence for the contribution of muscle stem cells to nonhypertrophic skeletal muscle remodeling in humans. FASEB J (27): 4596-4605.
93. Joseph AM, Malamo AG, Silvestre J, Wawrzyniak N, Carey-Love S, Nguyen LM, Dutta D, Xu J, Leeuwenburgh C, Adhihetty PJ (2013). Short-term caloric restriction, resveratrol, or combined treatment regimens initiated in late-life alter mitochondrial protein expression profiles in a fibertype specific manner in aged animals. Exp Gerontol (48): 858-868.
94. Kern H, Barberi L, Lofler S, Sbardella S, Burggraf S, Fruhmann H, Carraro U, Mosole S, Sarabon N, Vogelauer M, Mayr W, Krenn M, Cvecka J, Romanello V, Pietrangelo L, Protasi F, Sandri M, Zampieri S, Musaro A (2014). Electrical stimulation counteracts muscle decline in seniors. Front Aging Neurosci (6): 189.
95. Kim JS, Park YM, Lee SR, Masad IS, Khamoui AV, Jo E, Park BS, Arjmandi BH, Panton LB, Lee WJ, Grant SC (2012). beta-hydroxy-beta-methylbutyrate did not enhance high intensity resistance training-induced improvements in myofiber dimensions and myogenic capacity in aged female rats. Mol Cells (34): 439-448.
96. Kim TN & Choi KM (2013). Sarcopenia: Definition, Epidemiology, and Pathophysiology. J Bone Metab (20): 1-10.
97. Kim TN, Park MS, Yang SJ, Yoo HJ, Kang HJ, Song W, Seo JA, Kim SG, Kim NH, Baik SH, Choi DS, Choi KM (2010). Prevalence and determinant factors of sarcopenia in patients with type 2 diabetes: the Korean Sarcopenic Obesity Study (KSOS). Diabetes Care (33): 1497-1499.
98. Kornasio R, Riederer I, Butler-Browne G, Mouly V, Uni Z, Halevy O (2009a). Beta-hydroxybeta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. Biochim Biophys Acta (1793): 755-763.
99. Kornasio R, Riederer I, Butler-Browne G, Mouly V, Uni Z, Halevy O (2009b). Beta-hydroxybeta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. Biochim Biophys Acta (1793): 755-763.
100. Krajnak K, Waugh S, Miller R, Baker B, Geronilla K, Alway SE, Cutlip RG (2006). Proapoptotic factor Bax is increased in satellite cells in the tibialis anterior muscles of old rats. Muscle Nerve (34): 720-730.
101. Kuang S, Charge SB, Seale P, Huh M, Rudnicki MA (2006). Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis. J Cell Biol (172): 103-113.
102. Kwan P (2013). Sarcopenia: the gliogenic perspective. Mech Ageing Dev (134): 349-355.
103. Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T (2012). What does the concept of the stem cell niche really mean today? BMC Biol (10): 19.
104. Lee CE, McArdle A, Griffiths RD (2007). The role of hormones, cytokines and heat shock proteins during age-related muscle loss. Clin Nutr (26): 524-534.
105. Leeuwenburgh C (2003). Role of apoptosis in sarcopenia. J Gerontol A Biol Sci Med Sci (58): 999-1001.
106. Lepper C, Partridge TA, Fan CM (2011). An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development (138): 3639-3646.
107. Lin J, Handschin C, Spiegelman BM (2005). Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab (1): 361-370.
108. Ljubicic V, Joseph AM, Adhihetty PJ, Huang JH, Saleem A, Uguccioni G, Hood DA (2009). Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle. Aging (Albany NY) (1): 818-830.
109. Lowe DA, Lund T, Alway SE (1998). Hypertrophy-stimulated myogenic regulatory factor mRNA increases are attenuated in fast muscle of aged quails. Am J Physiol (275): C155-C162.
110. Machida S & Booth FW (2004). Increased nuclear proteins in muscle satellite cells in aged animals as compared to young growing animals. Exp Gerontol (39): 1521-1525.
111. Martinez-Hernandez R, Bernal S, Alias L, Tizzano EF (2014). Abnormalities in early markers of muscle involvement support a delay in myogenesis in spinal muscular atrophy. J Neuropathol Exp Neurol (73): 559-567.
112. Marzetti E, Calvani R, Cesari M, Buford TW, Lorenzi M, Behnke BJ, Leeuwenburgh C (2013). Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials. Int J Biochem Cell Biol (45): 2288-2301.
113. Marzetti E, Hwang JC, Lees HA, Wohlgemuth SE, Dupont-Versteegden EE, Carter CS, Bernabei R, Leeuwenburgh C (2010). Mitochondrial death effectors: relevance to sarcopenia and disuse muscle atrophy. Biochim Biophys Acta (1800): 235-244.
114. Marzetti E, Lees HA, Manini TM, Buford TW, Aranda JM, Jr., Calvani R, Capuani G, Marsiske M, Lott DJ, Vandenborne K, Bernabei R, Pahor M, Leeuwenburgh C, Wohlgemuth SE (2012). Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in communitydwelling older persons: an exploratory study. PLoS ONE (7): e32829.
115. Mauro A (1961). Satellite cell of skeletal muscle fibers. J Biophys, Biochem Cytol (9): 493-495.
116. Mavros Y, Kay S, Simpson KA, Baker MK, Wang Y, Zhao RR, Meiklejohn J, Climstein M, O'Sullivan AJ, de VN, Baune BT, Blair SN, Simar D, Rooney K, Singh NA, Fiatarone Singh MA (2014). Reductions in C-reactive protein in older adults with type 2 diabetes are related to improvements in body composition following a randomized controlled trial of resistance training. J Cachexia Sarcopenia Muscle.
117. McCarthy JJ, Mula J, Miyazaki M, Erfani R, Garrison K, Farooqui AB, Srikuea R, Lawson BA, Grimes B, Keller C, Van ZG, Campbell KS, Esser KA, Dupont-Versteegden EE, Peterson CA (2011). Effective fiber hypertrophy in satellite cell-depleted skeletal muscle. Development (138): 3657-3666.
118. McKay BR, O'Reilly CE, Phillips SM, Tarnopolsky MA, Parise G (2008). Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging musclelengthening contractions in humans. J Physiol (586): 5549-5560.
119. Michalakis K, Goulis DG, Vazaiou A, Mintziori G, Polymeris A, Abrahamian-Michalakis A (2013). Obesity in the ageing man. Metabolism (62): 1341-1349.
120. Minet AD & Gaster M (2012). Cultured senescent myoblasts derived from human vastus lateralis exhibit normal mitochondrial ATP synthesis capacities with correlating concomitant ROS production while whole cell ATP production is decreased. Biogerontology (13): 277-285.
121. Mirza KA, Pereira SL, Edens NK, Tisdale MJ (2014). Attenuation of muscle wasting in murine CC myotubes by epigallocatechin-3-gallate. J Cachexia Sarcopenia Muscle.
122. Montarras D, L'honore A, Buckingham M (2013). Lying low but ready for action: the quiescent muscle satellite cell. FEBS J (280): 4036-4050.
123. Moore DT, Ferket PR, Mozdziak PE (2005). The effect of early nutrition on satellite cell dynamics in the young turkey. Poult Sci (84): 748-756.
124. Mosole S, Carraro U, Kern H, Loefler S, Fruhmann H, Vogelauer M, Burggraf S, Mayr W, Krenn M, Paternostro-Sluga T, Hamar D, Cvecka J, Sedliak M, Tirpakova V, Sarabon N, Musaro A, Sandri M, Protasi F, Nori A, Pond A, Zampieri S (2014). Long-term high-level exercise promotes muscle reinnervation with age. J Neuropathol Exp Neurol (73): 284-294.
125. Moss FP & Leblond CP (1971). Satellite cells as the source of nuclei in muscles of growing rats. Anat Rec (170): 421-435.
126. Mozdziak PE, Walsh TJ, McCoy DW (2002). The effect of early posthatch nutrition on satellite cell mitotic activity. Poult Sci (81): 1703-1708.
127. Murlasits Z, Cutlip RG, Geronilla KB, Rao KM, Wonderlin WF, Alway SE (2006). Resistance training increases heat shock protein levels in skeletal muscle of young and old rats. Exp Gerontol (41): 398-406.
128. Murphy MM, Lawson JA, Mathew SJ, Hutcheson DA, Kardon G (2011). Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration. Development (138): 3625-3637.
129. Olguin HC & Olwin BB (2004). Pax-7 up-regulation inhibits myogenesis and cell cycle progression in satellite cells: a potential mechanism for self-renewal. Dev Biol (275): 375-388.
130. Olguin HC, Yang Z, Tapscott SJ, Olwin BB (2007). Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination. J Cell Biol (177): 769-779.
131. Ota N, Soga S, Haramizu S, Yokoi Y, Hase T, Murase T (2011). Tea catechins prevent contractile dysfunction in unloaded murine soleus muscle: a pilot study. Nutrition (27): 955-959.
132. Oustanina S, Hause G, Braun T (2004). Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification. EMBO J (23): 3430-3439.
133. Parise G, McKinnell IW, Rudnicki MA (2008). Muscle satellite cell and atypical myogenic progenitor response following exercise. Muscle Nerve (37): 611-619.
134. Pellegrino MA, Desaphy JF, Brocca L, Pierno S, Camerino DC, Bottinelli R (2011). Redox homeostasis, oxidative stress and disuse muscle atrophy. J Physiol (589): 2147-2160.
135. Phillips SM, Tipton KD, Aarsland A, Wolf SE, Wolfe RR (1997). Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol (273): E99-107.
136. Pistilli EE, Siu PM, Alway SE (2006). Molecular regulation of apoptosis in fast plantaris muscles of aged rats. J Gerontol A Biol Sci Med Sci (61): 245-255.
137. Powell DJ, McFarland DC, Cowieson AJ, Muir WI, Velleman SG (2013). The effect of nutritional status on myogenic satellite cell proliferation and differentiation. Poult Sci (92): 2163-2173.
138. Powell DJ, McFarland DC, Cowieson AJ, Muir WI, Velleman SG (2014). The effect of nutritional status and muscle fiber type on myogenic satellite cell fate and apoptosis. Poult Sci (93): 163-173.
139. Powers SK, Ji LL, Kavazis AN, Jackson MJ (2011). Reactive oxygen species: impact on skeletal muscle. Compr Physiol (1): 941-969.
140. Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de CR, Baur JA, Sinclair DA (2012). SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab (15): 675-690.
141. Purves-Smith FM, Sgarioto N, Hepple RT (2014). Fiber typing in aging muscle. Exerc Sport Sci Rev (42): 45-52.
142. Putman CT, Sultan KR, Wassmer T, Bamford JA, Skorjanc D, Pette D (2001). Fiber-type transitions and satellite cell activation in low-frequency-stimulated muscles of young and aging rats. J Gerontol A Biol Sci Med Sci (56): B510-B519.
143. Quadrilatero J, Alway SE, Dupont-Versteegden EE (2011). Skeletal muscle apoptotic response to physical activity: potential mechanisms for protection. Appl Physiol Nutr Metab (36): 608-617.
144. Rathbone CR, Booth FW, Lees SJ (2009). Sirt1 increases skeletal muscle precursor cell proliferation. Eur J Cell Biol (88): 35-44.
145. Relaix F, Montarras D, Zaffran S, Gayraud-Morel B, Rocancourt D, Tajbakhsh S, Mansouri A, Cumano A, Buckingham M (2006). Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. J Cell Biol (172): 91-102.
146. Renno WM, Al-Maghrebi M, Al-Banaw A (2012). (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury. Naunyn Schmiedebergs Arch Pharmacol (385): 807-822.
147. Rice CL, Cunningham DA, Paterson DH, Lefcoe MS (1989). Arm and leg composition determined by computed tomography in young and elderly men. Clin Physiol (9): 207-220.
148. Rudnicki MA, Le GF, McKinnell I, Kuang S (2008). The molecular regulation of muscle stem cell function. Cold Spring Harb Symp Quant Biol (73): 323-331.
149. Ryan MJ, Jackson s, Hao Y, Leonard SS, Alway SE (2011). Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice. Free Radic Biol Med (51): 38-52.
150. Ryan MJ, Jackson JR, Hao Y, Williamson CL, Dabkowski ER, Hollander JM, Alway SE (2010). Suppression of oxidative stress by resveratrol after isometric contractions in gastrocnemius muscles of aged mice. J Gerontol A Biol Sci Med Sci (65): 815-831.
151. Sambasivan R, Yao R, Kissenpfennig A, Van WL, Paldi A, Gayraud-Morel B, Guenou H, Malissen B, Tajbakhsh S, Galy A (2011). Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration. Development (138): 3647-3656.
152. Schmalbruch H & Hellhammer U (1977). The number of nuclei in adult rat muscles with special reference to satellite cells. Anat Rec (189): 169-175.
153. Schmalbruch H & Lewis DM (2000). Dynamics of nuclei of muscle fibers and connective tissue cells in normal and denervated rat muscles. Muscle Nerve (23): 617-626.
154. Schultz E, Gibson MC, Champion T (1978). Satellite cells are mitotically quiescent in mature mouse muscle: an EM and radioautographic study. J Exp Zool (206): 451-456.
155. Seale P, Ishibashi J, Scime A, Rudnicki MA (2004). Pax7 is necessary and sufficient for the myogenic specification of CD45+:Sca1+ stem cells from injured muscle. PLoS Biol (2): E130.
156. Seale P & Rudnicki MA (2000). A new look at the origin, function, and "stem-cell" status of muscle satellite cells. Dev Biol (218): 115-124.
157. Seale P, Sabourin LA, Girgis-Gabardo A, Mansouri A, Gruss P, Rudnicki MA (2000). Pax7 is required for the specification of myogenic satellite cells. Cell (102): 777-786.
158. Shefer G, Rauner G, Yablonka-Reuveni Z, Benayahu D (2010). Reduced satellite cell numbers and myogenic capacity in aging can be alleviated by endurance exercise. PLoS One (5): e13307.
159. Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ (2014). Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. Science (344): 649-652.
160. Siu PM & Alway SE (2009). Response and adaptation of skeletal muscle to denervation stress: the role of apoptosis in muscle loss. Front Biosci (14): 432-452.
161. Sjostrom M, Lexell J, Downham DY (1992). Differences in fiber number and fiber type proportion within fascicles. A quantitative morphological study of whole vastus lateralis muscle from childhood to old age. Anat Rec (234): 183-189.
162. Snijders T, Verdijk LB, Smeets JS, McKay BR, Senden JM, Hartgens F, Parise G, GreenhaffP, van Loon LJ (2014a). The skeletal muscle satellite cell response to a single bout of resistancetype exercise is delayed with aging in men. Age (Dordr) (36): 9699.
163. Snijders T, Verdijk LB, van Loon LJ (2009). The impact of sarcopenia and exercise training on skeletal muscle satellite cells. Ageing Res Rev (8): 328-338.
164. Snijders T, Wall BT, Dirks ML, Senden JM, Hartgens F, Dolmans J, Losen M, Verdijk LB, van Loon LJ (2014b). Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content. Clin Sci (Lond) (126): 557-566.
165. Snow MH (1977). The effects of aging on satellite cells in skeletal muscles of mice and rats. Cell Tissue Res (185): 399-408.
166. Sousa-Victor P, Gutarra S, Garcia-Prat L, Rodriguez-Ubreva J, Ortet L, Ruiz-Bonilla V, Jardi M, Ballestar E, Gonzalez S, Serrano AL, Perdiguero E, Munoz-Canoves P (2014). Geriatric muscle stem cells switch reversible quiescence into senescence. Nature (506): 316-321.
167. Spiegelman BM (2007). Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators. Novartis Found Symp (287): 60-63.
168. Stenholm S, Harris TB, Rantanen T, Visser M, Kritchevsky SB, Ferrucci L (2008). Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care (11): 693-700.
169. Stepto NK, Benziane B, Wadley GD, Chibalin AV, Canny BJ, Eynon N, McConell GK (2012). Short-term intensified cycle training alters acute and chronic responses of PGC1alpha and Cytochrome C oxidase IV to exercise in human skeletal muscle. PLoS ONE (7): e53080.
170. Suetta C, Frandsen U, Mackey AL, Jensen L, Hvid LG, Bayer ML, Petersson SJ, Schroder HD, Andersen JL, Aagaard P, Schjerling P, Kjaer M (2013). Ageing is associated with diminished muscle re-growth and myogenic precursor cell expansion early after immobility-induced atrophy in human skeletal muscle. J Physiol (591): 3789-3804.
171. Suetta C, Hvid LG, Justesen L, Christensen U, Neergaard K, Simonsen L, Ortenblad N, Magnusson SP, Kjaer M, Aagaard P (2009). Effects of aging on human skeletal muscle after immobilization and retraining. J Appl Physiol (1985) (107): 1172-1180.
172. Sullivan-Gunn MJ & Lewandowski PA (2013). Elevated hydrogen peroxide and decreased catalase and glutathione peroxidase protection are associated with aging sarcopenia. BMC Geriatr (13): 104.
173. Szczesny B, Olah G, Walker DK, Volpi E, Rasmussen BB, Szabo C, Mitra S (2013). Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage. PLoS ONE (8): e75201.
174. Tidball JG (2005). Inflammatory processes in muscle injury and repair. Am J Physiol Regul Integr Comp Physiol (288): R345-R353.
175. Tidball JG & Wehling-Henricks M (2007). Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo. J Physiol (578): 327-336.
176. Tinetti ME (2001). Where is the vision for fall prevention? J Am Geriatr Soc (49): 676-677.
177. Toledo M, Busquets S, Ametller E, Lopez-Soriano FJ, Argiles JM (2011). Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats: a role in impaired regeneration? J Cachexia Sarcopenia Muscle (2): 57-62.
178. Toth KG, McKay BR, De LM, Little JP, Tarnopolsky MA, Parise G (2011). IL-6 induced STAT3 signalling is associated with the proliferation of human muscle satellite cells following acute muscle damage. PLoS One (6): e17392.
179. van der Meer SF, Jaspers RT, Jones DA, Degens H (2011a). The time course of myonuclear accretion during hypertrophy in young adult and older rat plantaris muscle. Ann Anat (193): 56-63.
180. van der Meer SF, Jaspers RT, Jones DA, Degens H (2011b). Time-course of changes in the myonuclear domain during denervation in young-adult and old rat gastrocnemius muscle. Muscle Nerve (43): 212-222.
181. Vasilaki A & Jackson MJ (2013). Role of reactive oxygen species in the defective regeneration seen in aging muscle. Free Radic Biol Med (65): 317-323.
182. Velleman SG, Zhang X, Coy CS, Song Y, McFarland DC (2010). Changes in satellite cell proliferation and differentiation during turkey muscle development. Poult Sci (89): 709-715.
183. Verdijk LB, Dirks ML, Snijders T, Prompers JJ, Beelen M, Jonkers RA, Thijssen DH, Hopman MT, van Loon LJ (2012). Reduced satellite cell numbers with spinal cord injury and aging in humans. Med Sci Sports Exerc (44): 2322-2330.
184. Verdijk LB, Gleeson BG, Jonkers RA, Meijer K, Savelberg HH, Dendale P, van Loon LJ (2009). Skeletal muscle hypertrophy following resistance training is accompanied by a fiber typespecific increase in satellite cell content in elderly men. J Gerontol A Biol Sci Med Sci (64): 332-339.
185. Sullivan-Gunn MJ & Lewandowski PA (2013). Elevated hydrogen peroxide and decreased catalase and glutathione peroxidase protection are associated with aging sarcopenia. BMC Geriatr (13): 104.
186. Szczesny B, Olah G, Walker DK, Volpi E, Rasmussen BB, Szabo C, Mitra S (2013). Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage. PLoS ONE (8): e75201.
187. Tidball JG (2005). Inflammatory processes in muscle injury and repair. Am J Physiol Regul Integr Comp Physiol (288): R345-R353.
188. Tidball JG & Wehling-Henricks M (2007). Macrophages promote muscle membrane repair and muscle fibre growth and regeneration during modified muscle loading in mice in vivo. J Physiol (578): 327-336.
189. Tinetti ME (2001). Where is the vision for fall prevention? J Am Geriatr Soc (49): 676-677.
190. Toledo M, Busquets S, Ametller E, Lopez-Soriano FJ, Argiles JM (2011). Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats: a role in impaired regeneration? J Cachexia Sarcopenia Muscle (2): 57-62.
191. Toth KG, McKay BR, De LM, Little JP, Tarnopolsky MA, Parise G (2011). IL-6 induced STAT3 signalling is associated with the proliferation of human muscle satellite cells following acute muscle damage. PLoS One (6): e17392.
192. van der Meer SF, Jaspers RT, Jones DA, Degens H (2011a). The time course of myonuclear accretion during hypertrophy in young adult and older rat plantaris muscle. Ann Anat (193): 56-63.
193. van der Meer SF, Jaspers RT, Jones DA, Degens H (2011b). Time-course of changes in the myonuclear domain during denervation in young-adult and old rat gastrocnemius muscle. Muscle Nerve (43): 212-222.
194. Vasilaki A & Jackson MJ (2013). Role of reactive oxygen species in the defective regeneration seen in aging muscle. Free Radic Biol Med (65): 317-323.
195. Velleman SG, Zhang X, Coy CS, Song Y, McFarland DC (2010). Changes in satellite cell proliferation and differentiation during turkey muscle development. Poult Sci (89): 709-715.
196. Verdijk LB, Dirks ML, Snijders T, Prompers JJ, Beelen M, Jonkers RA, Thijssen DH, Hopman MT, van Loon LJ (2012). Reduced satellite cell numbers with spinal cord injury and aging in humans. Med Sci Sports Exerc (44): 2322-2330.
197. Verdijk LB, Gleeson BG, Jonkers RA, Meijer K, Savelberg HH, Dendale P, van Loon LJ (2009). Skeletal muscle hypertrophy following resistance training is accompanied by a fiber typespecific increase in satellite cell content in elderly men. J Gerontol A Biol Sci Med Sci (64): 332-339.
198. Verdijk LB, Koopman R, Schaart G, Meijer K, Savelberg HH, van Loon LJ (2007). Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly. Am J Physiol Endocrinol Metab (292): E151-E157.
199. Verdijk LB, Snijders T, Drost M, Delhaas T, Kadi F, van Loon LJ (2014). Satellite cells in human skeletal muscle; from birth to old age. Age (Dordr)36 545-547.
200. Vescovo G, Volterrani M, Zennaro R, Sandri M, Ceconi C, Lorusso R, Ferrari R, Ambrosio GB, Dalla LL (2000). Apoptosis in the skeletal muscle of patients with heart failure: investigation of clinical and biochemical changes. Heart (84): 431-437.
201. Vescovo G, Zennaro R, Sandri M, Carraro U, Leprotti C, Ceconi C, Ambrosio GB, Dalla LL (1998). Apoptosis of skeletal muscle myofibers and interstitial cells in experimental heart failure. J Mol Cell Cardiol (30): 2449-2459.
202. Vettor R, Milan G, Franzin C, Sanna M, De CP, Rizzuto R, Federspil G (2009). The origin of intermuscular adipose tissue and its pathophysiological implications. Am J Physiol Endocrinol Metab (297): E987-E998.
203. Vinciguerra M, Fulco M, Ladurner A, Sartorelli V, Rosenthal N (2010). SirT1 in muscle physiology and disease: lessons from mouse models. Dis Model Mech (3): 298-303.
204. von MJ, Jones AE, Parks RJ, Rudnicki MA (2013). Pax7 is critical for the normal function of satellite cells in adult skeletal muscle. Proc Natl Acad Sci U S A (110): 16474-16479.
205. Wang H, Lai YJ, Chan YL, Li TL, Wu CJ (2011). Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia. Cancer Lett (305): 40-49.
206. Wang X, Pickrell AM, Rossi SG, Pinto M, Dillon LM, Hida A, Rotundo RL, Moraes CT (2013). Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool. Hum Mol Genet (22): 3976-3986.
207. Welch AA (2014). Nutritional influences on age-related skeletal muscle loss. Proc Nutr Soc (73): 16-33.
208. Welch AA, MacGregor AJ, Minihane AM, Skinner J, Valdes AA, Spector TD, Cassidy A (2014). Dietary fat and fatty acid profile are associated with indices of skeletal muscle mass in women aged 18-79 years. J Nutr (144): 327-334.
209. Westerbacka J, Kolak M, Kiviluoto T, Arkkila P, Siren J, Hamsten A, Fisher RM, Yki-Jarvinen H (2007). Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects. Diabetes (56): 2759-2765.
210. Wilson GJ, Wilson JM, Manninen AH (2008). Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. Nutr Metab (Lond) (5): 1-17.
211. Wu D, Wang J, Pae M, Meydani SN (2012). Green tea EGCG, T cells, and T cell-mediated autoimmune diseases. Mol Aspects Med (33): 107-118.
212. Xu Z, Huang G, Gong W, Zhou P, Zhao Y, Zhang Y, Zeng Y, Gao M, Pan Z, He F (2012). FXR ligands protect against hepatocellular inflammation via SOCS3 induction. Cell Signal (24): 1658-1664.
213. Yablonka-Reuveni Z, Day K, Vine A, Shefer G. Defining the transcriptional signature of skeletal muscle stem cells. J Anim Sci 86: E207-E216. 2008