-
1
-
-
18644379136
-
The fatty liver and insulin resistance
-
Yki-Jarvinen H, Westerbacka J: The fatty liver and insulin resistance. Curr Mol Med 5:287-295, 2005
-
(2005)
Curr Mol Med
, vol.5
, pp. 287-295
-
-
Yki-Jarvinen, H.1
Westerbacka, J.2
-
2
-
-
0038644536
-
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
-
Neuschwander-Tetri BA, Caldwell SH: Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 37:1202-1219, 2003
-
(2003)
Hepatology
, vol.37
, pp. 1202-1219
-
-
Neuschwander-Tetri, B.A.1
Caldwell, S.H.2
-
3
-
-
0034604248
-
Chronic subclinical inflammation as part of the insulin resistance syndrome: The Insulin Resistance Atherosclerosis Study (IRAS)
-
Festa A, D'Agostino R Jr, Howard G, et al.: Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102:42-47, 2000
-
(2000)
Circulation
, vol.102
, pp. 42-47
-
-
Festa, A.1
D'Agostino Jr, R.2
Howard, G.3
-
4
-
-
0038809142
-
Monocyte chemoattractant protein 1 in obesity and insulin resistance
-
Sartipy P, Loskutoff DJ: Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci U S A 100:7265-7270, 2003
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 7265-7270
-
-
Sartipy, P.1
Loskutoff, D.J.2
-
5
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AW: CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 116:115-124, 2006
-
(2006)
J Clin Invest
, vol.116
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
Lemieux, J.4
Slaymaker, S.5
Vaddi, K.6
Charo, I.7
Leibel, R.L.8
Ferrante, A.W.9
-
6
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, et al.: Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796-1808, 2003
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
-
7
-
-
31444446947
-
Acute in vivo effects of insulin on gene expression in adipose tissue in insulin-resistant and insulin-sensitive subjects
-
Westerbacka J, Corner A, Kannisto K, et al.: Acute in vivo effects of insulin on gene expression in adipose tissue in insulin-resistant and insulin-sensitive subjects. Diabetologia 49:132-140, 2006
-
(2006)
Diabetologia
, vol.49
, pp. 132-140
-
-
Westerbacka, J.1
Corner, A.2
Kannisto, K.3
-
8
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, et al.: Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112:1821-1830, 2003
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
-
9
-
-
0037962069
-
Plasma PAI-1 levels are more strongly related to liver steatosis than to adipose tissue accumulation
-
Alessi MC, Bastelica D, Mavri A, et al.: Plasma PAI-1 levels are more strongly related to liver steatosis than to adipose tissue accumulation. Arterioscler Thromb Vasc Biol 23:1262-1268, 2003
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1262-1268
-
-
Alessi, M.C.1
Bastelica, D.2
Mavri, A.3
-
10
-
-
0037390373
-
Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy
-
Yki-Jarvinen H, Sutinen J, Silveira A, et al.: Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy. Arterioscler Thromb Vasc Biol 23:688-694, 2003
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 688-694
-
-
Yki-Jarvinen, H.1
Sutinen, J.2
Silveira, A.3
-
11
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly KL, Smith CI, Schwarzenberg SJ, et al.: Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115:1343-1351, 2005
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
-
12
-
-
33645994508
-
Targeted deletion of FATP5 reveals multiple functions in liver metabolism: Alterations in hepatic lipid homeostasis
-
Doege H, Baillie RA, Ortegon AM, et al.: Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis. Gastroenterology 130:1245-1258, 2006
-
(2006)
Gastroenterology
, vol.130
, pp. 1245-1258
-
-
Doege, H.1
Baillie, R.A.2
Ortegon, A.M.3
-
13
-
-
18244363982
-
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
-
Maeda K, Cao H, Kono K, et al.: Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab 1:107-119, 2005
-
(2005)
Cell Metab
, vol.1
, pp. 107-119
-
-
Maeda, K.1
Cao, H.2
Kono, K.3
-
14
-
-
33750998524
-
Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice
-
Newberry EP, Xie Y, Kennedy SM, et al.: Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice. Hepatology 44:1191-1205, 2006
-
(2006)
Hepatology
, vol.44
, pp. 1191-1205
-
-
Newberry, E.P.1
Xie, Y.2
Kennedy, S.M.3
-
15
-
-
0141446024
-
Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
Gavrilova O, Haluzik M, Matsusue K, et al.: Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem 278:34268-34276, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
-
16
-
-
2442641811
-
Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy
-
Sutinen J, Kannisto K, Korsheninnikova E, et al.: Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy. Am J Physiol Endocrinol Metab 286:E941-E949, 2004
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Sutinen, J.1
Kannisto, K.2
Korsheninnikova, E.3
-
17
-
-
24144503408
-
A genomic and proteomic study of the spectrum of nonalcoholic fatty liver disease
-
Younossi ZM, Baranova A, Ziegler K, et al.: A genomic and proteomic study of the spectrum of nonalcoholic fatty liver disease. Hepatology 42:665-674, 2005
-
(2005)
Hepatology
, vol.42
, pp. 665-674
-
-
Younossi, Z.M.1
Baranova, A.2
Ziegler, K.3
-
18
-
-
22844439963
-
Hepatic gene expression in patients with obesity-related non-alcoholic steatohepatitis
-
Younossi ZM, Gorreta F, Ong JP, et al.: Hepatic gene expression in patients with obesity-related non-alcoholic steatohepatitis. Liver Int 25:760-771, 2005
-
(2005)
Liver Int
, vol.25
, pp. 760-771
-
-
Younossi, Z.M.1
Gorreta, F.2
Ong, J.P.3
-
19
-
-
30944453514
-
Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray
-
Chiappini F, Barrier A, Saffroy R, et al.: Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray. Lab Invest 86:154-165, 2006
-
(2006)
Lab Invest
, vol.86
, pp. 154-165
-
-
Chiappini, F.1
Barrier, A.2
Saffroy, R.3
-
20
-
-
33646161443
-
Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2
-
Haukeland JW, Damas JK, Konopski Z, et al.: Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. J Hepatol 44:1167-1174, 2006
-
(2006)
J Hepatol
, vol.44
, pp. 1167-1174
-
-
Haukeland, J.W.1
Damas, J.K.2
Konopski, Z.3
-
21
-
-
32544436435
-
The multigene family of fatty acid-binding proteins (FABPs): Function, structure and polymorphism
-
Chmurzynska A: The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J Appl Genet 47:39-48, 2006
-
(2006)
J Appl Genet
, vol.47
, pp. 39-48
-
-
Chmurzynska, A.1
-
22
-
-
0025951065
-
Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression
-
Amri EZ, Bertrand B, Ailhaud G: Regulation of adipose cell differentiation. I. Fatty acids are inducers of the aP2 gene expression. J Lipid Res 32:1449-1456, 1991
-
(1991)
J Lipid Res
, vol.32
, pp. 1449-1456
-
-
Amri, E.Z.1
Bertrand, B.2
Ailhaud, G.3
-
23
-
-
0034959752
-
Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis
-
Makowski L, Boord JB, Maeda K, et al.: Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat Med 7:699-705, 2001
-
(2001)
Nat Med
, vol.7
, pp. 699-705
-
-
Makowski, L.1
Boord, J.B.2
Maeda, K.3
-
24
-
-
0027293808
-
Tumor-specific overexpression of a novel keratinocyte lipid-binding protein: Identification and characterization of a cloned sequence activated during multistage carcinogenesis in mouse skin
-
Krieg P, Feil S, Furstenberger G, et al.: Tumor-specific overexpression of a novel keratinocyte lipid-binding protein: identification and characterization of a cloned sequence activated during multistage carcinogenesis in mouse skin. J Biol Chem 268:17362-17369, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 17362-17369
-
-
Krieg, P.1
Feil, S.2
Furstenberger, G.3
-
25
-
-
0032933114
-
Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice
-
Memon RA, Fuller J, Moser AH, et al.: Regulation of putative fatty acid transporters and Acyl-CoA synthetase in liver and adipose tissue in ob/ob mice. Diabetes 48:121-127, 1999
-
(1999)
Diabetes
, vol.48
, pp. 121-127
-
-
Memon, R.A.1
Fuller, J.2
Moser, A.H.3
-
26
-
-
0023664546
-
The sequence of cDNA encoding lipoprotein lipase: A member of a lipase gene family
-
Kirchgessner TG, Svenson KL, Lusis AJ, et al.: The sequence of cDNA encoding lipoprotein lipase: a member of a lipase gene family. J Biol Chem 262:8463-8466, 1987
-
(1987)
J Biol Chem
, vol.262
, pp. 8463-8466
-
-
Kirchgessner, T.G.1
Svenson, K.L.2
Lusis, A.J.3
-
27
-
-
0035900749
-
Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta
-
Zhang Y, Repa JJ, Gauthier K, et al.: Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta. J Biol Chem 276:43018-43024, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 43018-43024
-
-
Zhang, Y.1
Repa, J.J.2
Gauthier, K.3
-
28
-
-
0023904495
-
Tissue-specific regulation of guinea pig lipoprotein lipase: Effects of nutritional state and of tumor necrosis factor on mRNA levels in adipose tissue, heart and liver
-
Enerback S, Semb H, Tavernier J, et al.: Tissue-specific regulation of guinea pig lipoprotein lipase: effects of nutritional state and of tumor necrosis factor on mRNA levels in adipose tissue, heart and liver. Gene 64:97-106, 1988
-
(1988)
Gene
, vol.64
, pp. 97-106
-
-
Enerback, S.1
Semb, H.2
Tavernier, J.3
-
29
-
-
0017616690
-
Pre- and post-natal development of lipoprotein lipase and hepatic triglyceride hydrolase activity in rat tissues
-
Chajek T, Stein O, Stein Y: Pre- and post-natal development of lipoprotein lipase and hepatic triglyceride hydrolase activity in rat tissues. Atherosclerosis 26:549-561, 1977
-
(1977)
Atherosclerosis
, vol.26
, pp. 549-561
-
-
Chajek, T.1
Stein, O.2
Stein, Y.3
-
30
-
-
0035912744
-
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
-
Kim JK, Fillmore JJ, Chen Y, et al.: Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc Natl Acad Sci U S A 98:7522-7527, 2001
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7522-7527
-
-
Kim, J.K.1
Fillmore, J.J.2
Chen, Y.3
-
31
-
-
0024390731
-
Effect of feeding and obesity on lipoprotein lipase activity, immunoreactive protein, and messenger RNA levels in human adipose tissue
-
Ong JM, Kern PA: Effect of feeding and obesity on lipoprotein lipase activity, immunoreactive protein, and messenger RNA levels in human adipose tissue. J Clin Invest 84:305-311, 1989
-
(1989)
J Clin Invest
, vol.84
, pp. 305-311
-
-
Ong, J.M.1
Kern, P.A.2
-
32
-
-
0036321931
-
Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways?
-
Coleman RA, Lewin TM, Van Horn CG, et al.: Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways? J Nutr 132:2123-2126, 2002
-
(2002)
J Nutr
, vol.132
, pp. 2123-2126
-
-
Coleman, R.A.1
Lewin, T.M.2
Van Horn, C.G.3
-
33
-
-
33748752324
-
Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet
-
Mashek DG, Li LO, Coleman RA: Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet. J Lipid Res 47:2004-2010, 2006
-
(2006)
J Lipid Res
, vol.47
, pp. 2004-2010
-
-
Mashek, D.G.1
Li, L.O.2
Coleman, R.A.3
-
34
-
-
33644861799
-
Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells
-
Mashek DG, McKenzie MA, Van Horn CG, et al.: Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells. J Biol Chem 281:945-950, 2006
-
(2006)
J Biol Chem
, vol.281
, pp. 945-950
-
-
Mashek, D.G.1
McKenzie, M.A.2
Van Horn, C.G.3
-
35
-
-
0031006469
-
A novel arachidonate-preferring acyl-CoA synthetase is present in steroidogenic cells of the rat adrenal, ovary, and testis
-
Kang MJ, Fujino T, Sasano H, et al.: A novel arachidonate-preferring acyl-CoA synthetase is present in steroidogenic cells of the rat adrenal, ovary, and testis. Proc Natl Acad Sci U S A 94:2880-2884, 1997
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2880-2884
-
-
Kang, M.J.1
Fujino, T.2
Sasano, H.3
-
36
-
-
0037373008
-
Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
-
Matsusue K, Haluzik M, Lambert G, et al.: Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J Clin Invest 111:737-747, 2003
-
(2003)
J Clin Invest
, vol.111
, pp. 737-747
-
-
Matsusue, K.1
Haluzik, M.2
Lambert, G.3
-
37
-
-
0346003777
-
Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression
-
Yu S, Matsusue K, Kashireddy P, et al.: Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J Biol Chem 278:498-505, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 498-505
-
-
Yu, S.1
Matsusue, K.2
Kashireddy, P.3
-
39
-
-
0842263981
-
The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
-
Ferre P: The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 53 (Suppl. 1):S43-S50, 2004
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Ferre, P.1
-
40
-
-
0037342842
-
Effects of identical weight loss on body composition and features of insulin resistance in obese women with high and low liver fat content
-
Tiikkainen M, Bergholm R, Vehkavaara S, et al.: Effects of identical weight loss on body composition and features of insulin resistance in obese women with high and low liver fat content. Diabetes 52:701-707, 2003
-
(2003)
Diabetes
, vol.52
, pp. 701-707
-
-
Tiikkainen, M.1
Bergholm, R.2
Vehkavaara, S.3
-
41
-
-
15444364990
-
Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins
-
Pietilainen KH, Rissanen A, Kaprio J, et al.: Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins. Am J Physiol Endocrinol Metab 288: E768-E774, 2005
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Pietilainen, K.H.1
Rissanen, A.2
Kaprio, J.3
-
42
-
-
18844458833
-
Dietary fat content modifies liver fat in overweight nondiabetic subjects
-
Westerbacka J, Lammi K, Hakkinen AM, et al.: Dietary fat content modifies liver fat in overweight nondiabetic subjects. J Clin Endocrinol Metab 90:2804-2809, 2005
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 2804-2809
-
-
Westerbacka, J.1
Lammi, K.2
Hakkinen, A.M.3
-
43
-
-
34047269605
-
Stearoyl CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat
-
Sampath H, Miyazaki M, Dobrzyn A, et al.: Stearoyl CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. J Biol Chem 282:2483-2493, 2007
-
(2007)
J Biol Chem
, vol.282
, pp. 2483-2493
-
-
Sampath, H.1
Miyazaki, M.2
Dobrzyn, A.3
-
44
-
-
19944430411
-
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP
-
Lin J, Yang R, Tarr PT, et al.: Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. Cell 120:261-273, 2005
-
(2005)
Cell
, vol.120
, pp. 261-273
-
-
Lin, J.1
Yang, R.2
Tarr, P.T.3
-
45
-
-
0034730532
-
The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1
-
Miyazaki M, Kim YC, Gray-Keller MP, et al.: The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. J Biol Chem 275:30132-30138, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 30132-30138
-
-
Miyazaki, M.1
Kim, Y.C.2
Gray-Keller, M.P.3
-
46
-
-
0035851187
-
PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen ED, Spiegelman BM: PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 276:37731-37734, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
47
-
-
33646497429
-
Regulation of adiponectin receptors in hepatocytes by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone
-
Sun X, Han R, Wang Z, et al.: Regulation of adiponectin receptors in hepatocytes by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. Diabetologia 49:1303-1310, 2006
-
(2006)
Diabetologia
, vol.49
, pp. 1303-1310
-
-
Sun, X.1
Han, R.2
Wang, Z.3
-
48
-
-
19244365650
-
Thiazolidinediones
-
Yki-Jarvinen H: Thiazolidinediones. N Engl J Med 351:1106-1118, 2004
-
(2004)
N Engl J Med
, vol.351
, pp. 1106-1118
-
-
Yki-Jarvinen, H.1
|