메뉴 건너뛰기




Volumn 29, Issue 11, 2014, Pages 1162-1171

The role of epigenetics in cognitive ageing

Author keywords

Ageing; Cognitive ageing; epigenetics; DNA methylation; histones; Gene expression; RNA

Indexed keywords

HISTONE; UNTRANSLATED RNA; HISTONE DEACETYLASE INHIBITOR;

EID: 84907891524     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.4183     Document Type: Article
Times cited : (18)

References (99)
  • 2
    • 84897365914 scopus 로고    scopus 로고
    • Characterizing cognitive aging in humans with links to animal models
    • Alexander GE, Ryan L, Bowers D, et al. 2012. Characterizing cognitive aging in humans with links to animal models. Front Aging Neurosci 4: 21.
    • (2012) Front Aging Neurosci , vol.4 , pp. 21
    • Alexander, G.E.1    Ryan, L.2    Bowers, D.3
  • 3
    • 79954629042 scopus 로고    scopus 로고
    • Long-lasting and transgenerational effects of an environmental enrichment on memory formation
    • Arai JA, Feig LA. 2011. Long-lasting and transgenerational effects of an environmental enrichment on memory formation. Brain Res Bull 85: 30-35.
    • (2011) Brain Res Bull , vol.85 , pp. 30-35
    • Arai, J.A.1    Feig, L.A.2
  • 4
    • 84899949628 scopus 로고    scopus 로고
    • Present and future of anti-ageing epigenetic diets
    • Bacalini MG, Friso S, Olivieri F, et al. 2014. Present and future of anti-ageing epigenetic diets. Mech Ageing Dev 136-137: 101-115.
    • (2014) Mech Ageing Dev , vol.136-137 , pp. 101-115
    • Bacalini, M.G.1    Friso, S.2    Olivieri, F.3
  • 5
    • 85027948621 scopus 로고    scopus 로고
    • Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory
    • Barrett RM, Malvaez M, Kramar E, et al. 2011. Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory. Neuropsychopharmacology 36: 1545-1556.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1545-1556
    • Barrett, R.M.1    Malvaez, M.2    Kramar, E.3
  • 6
    • 47549109984 scopus 로고    scopus 로고
    • Beyond transcription factors: The role of chromatin modifying enzymes in regulating transcription required for memory
    • Barrett RM, Wood MA. 2008. Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory. Learn Mem 15: 460-467.
    • (2008) Learn Mem , vol.15 , pp. 460-467
    • Barrett, R.M.1    Wood, M.A.2
  • 7
    • 45849127657 scopus 로고    scopus 로고
    • Intra-individual change over time in DNA methylation with familial clustering
    • Bjornsson HT, Sigurdsson MI, Fallin MD, et al. 2008. Intra-individual change over time in DNA methylation with familial clustering. JAMA 299: 2877-2883.
    • (2008) JAMA , vol.299 , pp. 2877-2883
    • Bjornsson, H.T.1    Sigurdsson, M.I.2    Fallin, M.D.3
  • 8
    • 0038206578 scopus 로고    scopus 로고
    • Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment
    • Blalock EM, Chen KC, Sharrow K, et al. 2003. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 23: 3807-3819.
    • (2003) J Neurosci , vol.23 , pp. 3807-3819
    • Blalock, E.M.1    Chen, K.C.2    Sharrow, K.3
  • 9
    • 84863281305 scopus 로고    scopus 로고
    • Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus
    • Castellano JF, Fletcher BR, Kelley-Bell B, et al. 2012. Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus. PLoS One 7: e33249.
    • (2012) PLoS One , vol.7 , pp. e33249
    • Castellano, J.F.1    Fletcher, B.R.2    Kelley-Bell, B.3
  • 10
    • 79954838543 scopus 로고    scopus 로고
    • Caloric restriction attenuates age-related changes of DNA methyltransferase 3a in mouse hippocampus
    • Chouliaras L, Van Den Hove DL, Kenis G, et al. 2011. Caloric restriction attenuates age-related changes of DNA methyltransferase 3a in mouse hippocampus. Brain Behav Immun 25: 616-623.
    • (2011) Brain Behav Immun , vol.25 , pp. 616-623
    • Chouliaras, L.1    Van Den Hove, D.L.2    Kenis, G.3
  • 11
    • 84861894813 scopus 로고    scopus 로고
    • Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction
    • Chouliaras L, Van Den Hove DL, Kenis G, et al. 2012. Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction. Neurobiol Aging 33: 1672-1681.
    • (2012) Neurobiol Aging , vol.33 , pp. 1672-1681
    • Chouliaras, L.1    Van Den Hove, D.L.2    Kenis, G.3
  • 14
    • 84879507076 scopus 로고    scopus 로고
    • Region- and age-specific patterns of histone acetylation related to spatial and cued learning in the water maze
    • Dagnas M, Mons N. 2013. Region- and age-specific patterns of histone acetylation related to spatial and cued learning in the water maze. Hippocampus 23: 581-591.
    • (2013) Hippocampus , vol.23 , pp. 581-591
    • Dagnas, M.1    Mons, N.2
  • 15
    • 79955141404 scopus 로고    scopus 로고
    • Histone H3 acetylation is asymmetrically induced upon learning in identified neurons of the food aversion network in the mollusk Helix lucorum
    • Danilova AB, Kharchenko OA, Shevchenko KG, Grinkevich LN. 2010. Histone H3 acetylation is asymmetrically induced upon learning in identified neurons of the food aversion network in the mollusk Helix lucorum. Front Behav Neurosci 4: 180.
    • (2010) Front Behav Neurosci , vol.4 , pp. 180
    • Danilova, A.B.1    Kharchenko, O.A.2    Shevchenko, K.G.3    Grinkevich, L.N.4
  • 16
    • 0037775776 scopus 로고    scopus 로고
    • Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice
    • Dickey CA, Loring JF, Montgomery J, et al. 2003. Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice. J Neurosci 23: 5219-5226.
    • (2003) J Neurosci , vol.23 , pp. 5219-5226
    • Dickey, C.A.1    Loring, J.F.2    Montgomery, J.3
  • 17
    • 84865757142 scopus 로고    scopus 로고
    • Landscape of transcription in human cells
    • Djebali S, Davis CA, Merkel A, et al. 2012. Landscape of transcription in human cells. Nature 489: 101-108.
    • (2012) Nature , vol.489 , pp. 101-108
    • Djebali, S.1    Davis, C.A.2    Merkel, A.3
  • 18
  • 19
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Encode PC, Bernstein BE, Birney E, et al. 2012. An integrated encyclopedia of DNA elements in the human genome. Nature 489: 57-74.
    • (2012) Nature , vol.489 , pp. 57-74
    • Encode, P.C.1    Bernstein, B.E.2    Birney, E.3
  • 20
    • 82755187564 scopus 로고    scopus 로고
    • Extracellular microRNA: A new source of biomarkers
    • Etheridge A, Lee I, Hood L, Galas D, Wang K. 2011. Extracellular microRNA: a new source of biomarkers. Mutat Res 717: 85-90.
    • (2011) Mutat Res , vol.717 , pp. 85-90
    • Etheridge, A.1    Lee, I.2    Hood, L.3    Galas, D.4    Wang, K.5
  • 21
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J, Zhou Y, Campbell SL, et al. 2010. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 13: 423-430.
    • (2010) Nat Neurosci , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3
  • 22
    • 34248523169 scopus 로고    scopus 로고
    • Recovery of learning and memory is associated with chromatin remodelling
    • Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH. 2007. Recovery of learning and memory is associated with chromatin remodelling. Nature 447: 178-182.
    • (2007) Nature , vol.447 , pp. 178-182
    • Fischer, A.1    Sananbenesi, F.2    Wang, X.3    Dobbin, M.4    Tsai, L.H.5
  • 23
    • 46149096244 scopus 로고    scopus 로고
    • Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system
    • Flavell SW, Greenberg ME. 2008. Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system. Annu Rev Neurosci 31: 563-590.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 563-590
    • Flavell, S.W.1    Greenberg, M.E.2
  • 25
    • 23044514669 scopus 로고    scopus 로고
    • Epigenetic differences arise during the lifetime of monozygotic twins
    • Fraga MF, Ballestar E, Paz MF, et al. 2005. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A 102: 10604-10609.
    • (2005) Proc Natl Acad Sci U S a , vol.102 , pp. 10604-10609
    • Fraga, M.F.1    Ballestar, E.2    Paz, M.F.3
  • 26
    • 84886707219 scopus 로고    scopus 로고
    • Epigenetics, estradiol, and hippocampal memory consolidation
    • Frick KM. 2013. Epigenetics, estradiol, and hippocampal memory consolidation. J Neuroendocrinol 25: 1151-1162.
    • (2013) J Neuroendocrinol , vol.25 , pp. 1151-1162
    • Frick, K.M.1
  • 27
    • 0036328453 scopus 로고    scopus 로고
    • Gene-nutrient interactions and DNA methylation
    • Friso S, Choi SW. 2002. Gene-nutrient interactions and DNA methylation. J Nutr 132: 2382S-2387S.
    • (2002) J Nutr , vol.132 , pp. 2382S-2387S
    • Friso, S.1    Choi, S.W.2
  • 28
    • 84894482720 scopus 로고    scopus 로고
    • Vascular risk factors and cognitive decline in a population sample
    • Ganguli M, Fu B, Snitz BE, et al. 2013. Vascular risk factors and cognitive decline in a population sample. Alzheimer Dis Assoc Disord 28(1): 9-15.
    • (2013) Alzheimer Dis Assoc Disord , vol.28 , Issue.1 , pp. 9-15
    • Ganguli, M.1    Fu, B.2    Snitz, B.E.3
  • 29
    • 84889562869 scopus 로고    scopus 로고
    • Valproate reopens critical-period learning of absolute pitch
    • Gervain J, Vines BW, Chen LM, et al. 2013. Valproate reopens critical-period learning of absolute pitch. Front Syst Neurosci 7: 102.
    • (2013) Front Syst Neurosci , vol.7 , pp. 102
    • Gervain, J.1    Vines, B.W.2    Chen, L.M.3
  • 30
    • 84871420316 scopus 로고    scopus 로고
    • Age-related changes in the global DNA methylation profile of leukocytes are linked to nutrition but are not associated with the MTHFR C677T genotype or to functional capacities
    • Gomes MV, Toffoli LV, Arruda DW, et al. 2012. Age-related changes in the global DNA methylation profile of leukocytes are linked to nutrition but are not associated with the MTHFR C677T genotype or to functional capacities. PLoS One 7: e52570.
    • (2012) PLoS One , vol.7 , pp. e52570
    • Gomes, M.V.1    Toffoli, L.V.2    Arruda, D.W.3
  • 32
    • 67649867069 scopus 로고    scopus 로고
    • Epigenetic dysregulation in cognitive disorders
    • Graff J, Mansuy IM. 2009. Epigenetic dysregulation in cognitive disorders. Eur J Neurosci 30: 1-8.
    • (2009) Eur J Neurosci , vol.30 , pp. 1-8
    • Graff, J.1    Mansuy, I.M.2
  • 33
    • 84872224226 scopus 로고    scopus 로고
    • The potential of HDAC inhibitors as cognitive enhancers
    • Graff J, Tsai LH. 2013. The potential of HDAC inhibitors as cognitive enhancers. Annu Rev Pharmacol Toxicol 53: 311-330.
    • (2013) Annu Rev Pharmacol Toxicol , vol.53 , pp. 311-330
    • Graff, J.1    Tsai, L.H.2
  • 34
    • 84876679234 scopus 로고    scopus 로고
    • Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation
    • Graff J, Woldemichael BT, Berchtold D, Dewarrat G, Mansuy IM. 2012. Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation. Nat Commun 3: 991.
    • (2012) Nat Commun , vol.3 , pp. 991
    • Graff, J.1    Woldemichael, B.T.2    Berchtold, D.3    Dewarrat, G.4    Mansuy, I.M.5
  • 35
    • 73749085370 scopus 로고    scopus 로고
    • Epigenetic factors in aging and longevity
    • Gravina S, Vijg J. 2010. Epigenetic factors in aging and longevity. Pflugers Arch 459: 247-258.
    • (2010) Pflugers Arch , vol.459 , pp. 247-258
    • Gravina, S.1    Vijg, J.2
  • 36
    • 84872716399 scopus 로고    scopus 로고
    • MicroRNA-182 regulates amygdala-dependent memory formation
    • Griggs EM, Young EJ, Rumbaugh G, Miller CA. 2013. MicroRNA-182 regulates amygdala-dependent memory formation. J Neurosci 33: 1734-1740.
    • (2013) J Neurosci , vol.33 , pp. 1734-1740
    • Griggs, E.M.1    Young, E.J.2    Rumbaugh, G.3    Miller, C.A.4
  • 37
    • 65549123471 scopus 로고    scopus 로고
    • HDAC2 negatively regulates memory formation and synaptic plasticity
    • Guan JS, Haggarty SJ, Giacometti E, et al. 2009. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459: 55-60.
    • (2009) Nature , vol.459 , pp. 55-60
    • Guan, J.S.1    Haggarty, S.J.2    Giacometti, E.3
  • 38
    • 0034213297 scopus 로고    scopus 로고
    • Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory
    • Guzowski JF, Lyford GL, Stevenson GD, et al. 2000. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci 20: 3993-4001.
    • (2000) J Neurosci , vol.20 , pp. 3993-4001
    • Guzowski, J.F.1    Lyford, G.L.2    Stevenson, G.D.3
  • 39
    • 0034114247 scopus 로고    scopus 로고
    • Rapid and selective induction of BDNF expression in the hippocampus during contextual learning
    • Hall J, Thomas KL, Everitt BJ. 2000. Rapid and selective induction of BDNF expression in the hippocampus during contextual learning. Nat Neurosci 3: 533-535.
    • (2000) Nat Neurosci , vol.3 , pp. 533-535
    • Hall, J.1    Thomas, K.L.2    Everitt, B.J.3
  • 40
    • 0027745794 scopus 로고
    • Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro
    • Hass BS, Hart RW, Lu MH, Lyn-Cook BD. 1993. Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro. Mutat Res 295: 281-289.
    • (1993) Mutat Res , vol.295 , pp. 281-289
    • Hass, B.S.1    Hart, R.W.2    Lu, M.H.3    Lyn-Cook, B.D.4
  • 41
    • 84887013185 scopus 로고    scopus 로고
    • The central dogma decentralized: New perspectives on RNA function and local translation in neurons
    • Holt CE, Schuman EM. 2013. The central dogma decentralized: new perspectives on RNA function and local translation in neurons. Neuron 80: 648-657.
    • (2013) Neuron , vol.80 , pp. 648-657
    • Holt, C.E.1    Schuman, E.M.2
  • 42
    • 84882452653 scopus 로고    scopus 로고
    • Exercise and sodium butyrate transform a subthreshold learning event into long-term memory via a brain-derived neurotrophic factor-dependent mechanism
    • Intlekofer KA, Berchtold NC, Malvaez M, et al. 2013. Exercise and sodium butyrate transform a subthreshold learning event into long-term memory via a brain-derived neurotrophic factor-dependent mechanism. Neuropsychopharmacology 38: 2027-2034.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 2027-2034
    • Intlekofer, K.A.1    Berchtold, N.C.2    Malvaez, M.3
  • 43
    • 84888329506 scopus 로고    scopus 로고
    • Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing
    • Jenjaroenpun P, Kremenska Y, Nair VM, et al. 2013. Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing. PeerJ 1: e201.
    • (2013) PeerJ , vol.1 , pp. e201
    • Jenjaroenpun, P.1    Kremenska, Y.2    Nair, V.M.3
  • 44
    • 58149347147 scopus 로고    scopus 로고
    • Epigenetics in the nervous system
    • Jiang Y, Langley B, Lubin FD, et al. 2008. Epigenetics in the nervous system. J Neurosci 28: 11753-11759.
    • (2008) J Neurosci , vol.28 , pp. 11753-11759
    • Jiang, Y.1    Langley, B.2    Lubin, F.D.3
  • 45
    • 84890441146 scopus 로고    scopus 로고
    • Role of BDNF epigenetics in activity-dependent neuronal plasticity
    • Karpova NN. 2014. Role of BDNF epigenetics in activity-dependent neuronal plasticity. Neuropharmacology 76 Pt C: 709-718.
    • (2014) Neuropharmacology , vol.76 , Issue.PART C , pp. 709-718
    • Karpova, N.N.1
  • 46
    • 84880864749 scopus 로고    scopus 로고
    • Histone modifications for human epigenome analysis
    • Kimura H. 2013. Histone modifications for human epigenome analysis. J Hum Genet 58: 439-445.
    • (2013) J Hum Genet , vol.58 , pp. 439-445
    • Kimura, H.1
  • 47
    • 78049520499 scopus 로고    scopus 로고
    • MicroRNA loss enhances learning and memory in mice
    • Konopka W, Kiryk A, Novak M, et al. 2010. MicroRNA loss enhances learning and memory in mice. J Neurosci 30: 14835-14842.
    • (2010) J Neurosci , vol.30 , pp. 14835-14842
    • Konopka, W.1    Kiryk, A.2    Novak, M.3
  • 48
    • 84863647710 scopus 로고    scopus 로고
    • Mechanisms of age-related cognitive change and targets for intervention: Epigenetics
    • Kosik KS, Rapp PR, Raz N, et al. 2012. Mechanisms of age-related cognitive change and targets for intervention: epigenetics. J Gerontol A Biol Sci Med Sci 67: 741-746.
    • (2012) J Gerontol a Biol Sci Med Sci , vol.67 , pp. 741-746
    • Kosik, K.S.1    Rapp, P.R.2    Raz, N.3
  • 49
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. 2007. Chromatin modifications and their function. Cell 128: 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 50
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek A, Grun D, Poy MN, et al. 2005. Combinatorial microRNA target predictions. Nat Genet 37: 495-500.
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.N.3
  • 51
    • 84863007261 scopus 로고    scopus 로고
    • The "LEARn" (latent early-life associated regulation) model: An epigenetic pathway linking metabolic and cognitive disorders
    • Lahiri DK, Maloney B. 2012. The "LEARn" (latent early-life associated regulation) model: an epigenetic pathway linking metabolic and cognitive disorders. J Alzheimers Dis 30(Suppl 2): S15-S30.
    • (2012) J Alzheimers Dis , vol.30 , pp. S15-S30
    • Lahiri, D.K.1    Maloney, B.2
  • 52
    • 70350432817 scopus 로고    scopus 로고
    • The LEARn model: An epigenetic explanation for idiopathic neurobiological diseases
    • Lahiri DK, Maloney B, Zawia NH. 2009. The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases. Mol Psychiatry 14: 992-1003.
    • (2009) Mol Psychiatry , vol.14 , pp. 992-1003
    • Lahiri, D.K.1    Maloney, B.2    Zawia, N.H.3
  • 53
    • 84866373102 scopus 로고    scopus 로고
    • Role of exosomes/microvesicles in the nervous system and use in emerging therapies
    • Lai CP, Breakefield XO. 2012. Role of exosomes/microvesicles in the nervous system and use in emerging therapies. Front Physiol 3: 228.
    • (2012) Front Physiol , vol.3 , pp. 228
    • Lai, C.P.1    Breakefield, X.O.2
  • 54
    • 33947532026 scopus 로고    scopus 로고
    • Histone acetyltransferase complexes: One size doesn't fit all
    • Lee KK, Workman JL. 2007. Histone acetyltransferase complexes: one size doesn't fit all. Nat Rev Mol Cell Biol 8: 284-295.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 284-295
    • Lee, K.K.1    Workman, J.L.2
  • 55
    • 84883499033 scopus 로고    scopus 로고
    • Cigarette smoking and DNA methylation
    • Lee KW, Pausova Z. 2013. Cigarette smoking and DNA methylation. Front Genet 4: 132.
    • (2013) Front Genet , vol.4 , pp. 132
    • Lee, K.W.1    Pausova, Z.2
  • 56
    • 33744920106 scopus 로고    scopus 로고
    • Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus
    • Levenson JM, Roth TL, Lubin FD, et al. 2006. Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J Biol Chem 281: 15763-15773.
    • (2006) J Biol Chem , vol.281 , pp. 15763-15773
    • Levenson, J.M.1    Roth, T.L.2    Lubin, F.D.3
  • 58
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P, et al. 2005. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433: 769-773.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3
  • 59
    • 84900791270 scopus 로고    scopus 로고
    • Developmental changes in the transcriptome of human cerebral cortex tissue: Long noncoding RNA transcripts
    • Lipovich L, Tarca AL, Cai J, et al. 2014. Developmental changes in the transcriptome of human cerebral cortex tissue: long noncoding RNA transcripts. Cereb Cortex 24: 1451-1459.
    • (2014) Cereb Cortex , vol.24 , pp. 1451-1459
    • Lipovich, L.1    Tarca, A.L.2    Cai, J.3
  • 60
    • 84873701571 scopus 로고    scopus 로고
    • Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus
    • Lovatel GA, Elsner VR, Bertoldi K, et al. 2013. Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus. Neurobiol Learn Mem 101: 94-102.
    • (2013) Neurobiol Learn Mem , vol.101 , pp. 94-102
    • Lovatel, G.A.1    Elsner, V.R.2    Bertoldi, K.3
  • 61
    • 79957999131 scopus 로고    scopus 로고
    • Epigenetic gene regulation in the adult mammalian brain: Multiple roles in memory formation
    • Lubin FD. 2011. Epigenetic gene regulation in the adult mammalian brain: multiple roles in memory formation. Neurobiol Learn Mem 96: 68-78.
    • (2011) Neurobiol Learn Mem , vol.96 , pp. 68-78
    • Lubin, F.D.1
  • 62
    • 54849426071 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory
    • Lubin FD, Roth TL, Sweatt JD. 2008. Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci 28: 10576-10586.
    • (2008) J Neurosci , vol.28 , pp. 10576-10586
    • Lubin, F.D.1    Roth, T.L.2    Sweatt, J.D.3
  • 63
    • 84895883542 scopus 로고    scopus 로고
    • DNA methylation and childhood maltreatment: From animal models to human studies
    • Lutz PE, Turecki G. 2013. DNA methylation and childhood maltreatment: from animal models to human studies. Neuroscience 264: 142-156.
    • (2013) Neuroscience , vol.264 , pp. 142-156
    • Lutz, P.E.1    Turecki, G.2
  • 64
    • 77958605856 scopus 로고    scopus 로고
    • Epigenetic choreographers of neurogenesis in the adult mammalian brain
    • Ma DK, Marchetto MC, Guo JU, et al. 2010. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci 13: 1338-1344.
    • (2010) Nat Neurosci , vol.13 , pp. 1338-1344
    • Ma, D.K.1    Marchetto, M.C.2    Guo, J.U.3
  • 65
    • 84861123503 scopus 로고    scopus 로고
    • Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model
    • Maloney B, Sambamurti K, Zawia N, Lahiri DK. 2012. Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model. Curr Alzheimer Res 9: 589-599.
    • (2012) Curr Alzheimer Res , vol.9 , pp. 589-599
    • Maloney, B.1    Sambamurti, K.2    Zawia, N.3    Lahiri, D.K.4
  • 66
    • 79958769568 scopus 로고    scopus 로고
    • Epigenetic mechanisms in Alzheimer's disease
    • Mastroeni D, Grover A, Delvaux E, et al. 2011. Epigenetic mechanisms in Alzheimer's disease. Neurobiol Aging 32: 1161-1180.
    • (2011) Neurobiol Aging , vol.32 , pp. 1161-1180
    • Mastroeni, D.1    Grover, A.2    Delvaux, E.3
  • 67
    • 77952887606 scopus 로고    scopus 로고
    • The epigenetics of social adversity in early life: Implications for mental health outcomes
    • Mcgowan PO, Szyf M. 2010. The epigenetics of social adversity in early life: implications for mental health outcomes. Neurobiol Dis 39: 66-72.
    • (2010) Neurobiol Dis , vol.39 , pp. 66-72
    • Mcgowan, P.O.1    Szyf, M.2
  • 68
    • 77954855825 scopus 로고    scopus 로고
    • SIRT1 is essential for normal cognitive function and synaptic plasticity
    • Michan S, Li Y, Chou MM, et al. 2010. SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci 30: 9695-9707.
    • (2010) J Neurosci , vol.30 , pp. 9695-9707
    • Michan, S.1    Li, Y.2    Chou, M.M.3
  • 69
    • 77952886110 scopus 로고    scopus 로고
    • Cortical DNA methylation maintains remote memory
    • Miller CA, Gavin CF, White JA, et al. 2010. Cortical DNA methylation maintains remote memory. Nat Neurosci 13: 664-666.
    • (2010) Nat Neurosci , vol.13 , pp. 664-666
    • Miller, C.A.1    Gavin, C.F.2    White, J.A.3
  • 70
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller CA, Sweatt JD. 2007. Covalent modification of DNA regulates memory formation. Neuron 53: 857-869.
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 71
    • 84864127740 scopus 로고    scopus 로고
    • Long-lasting regulation of hippocampal Bdnf gene transcription after contextual fear conditioning
    • Mizuno K, Dempster E, Mill J, Giese KP. 2012. Long-lasting regulation of hippocampal Bdnf gene transcription after contextual fear conditioning. Genes Brain Behav 11: 651-659.
    • (2012) Genes Brain Behav , vol.11 , pp. 651-659
    • Mizuno, K.1    Dempster, E.2    Mill, J.3    Giese, K.P.4
  • 72
    • 84860353437 scopus 로고    scopus 로고
    • Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
    • Modarresi F, Faghihi MA, Lopez-Toledano MA, et al. 2012. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat Biotechnol 30: 453-459.
    • (2012) Nat Biotechnol , vol.30 , pp. 453-459
    • Modarresi, F.1    Faghihi, M.A.2    Lopez-Toledano, M.A.3
  • 73
    • 77954996105 scopus 로고    scopus 로고
    • MiR-107 is reduced in Alzheimer's disease brain neocortex: Validation study
    • Nelson PT, Wang WX. 2010. MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. J Alzheimers Dis 21: 75-79.
    • (2010) J Alzheimers Dis , vol.21 , pp. 75-79
    • Nelson, P.T.1    Wang, W.X.2
  • 75
    • 84864461542 scopus 로고    scopus 로고
    • Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities
    • Oliveira AM, Hemstedt TJ, Bading H. 2012. Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities. Nat Neurosci 15: 1111-1113.
    • (2012) Nat Neurosci , vol.15 , pp. 1111-1113
    • Oliveira, A.M.1    Hemstedt, T.J.2    Bading, H.3
  • 76
    • 34748917182 scopus 로고    scopus 로고
    • Transgenic mice expressing an inhibitory truncated form of p300 exhibit long-term memory deficits
    • Oliveira AM, Wood MA, Mcdonough CB, Abel T. 2007. Transgenic mice expressing an inhibitory truncated form of p300 exhibit long-term memory deficits. Learn Mem 14: 564-572.
    • (2007) Learn Mem , vol.14 , pp. 564-572
    • Oliveira, A.M.1    Wood, M.A.2    Mcdonough, C.B.3    Abel, T.4
  • 77
    • 77952168294 scopus 로고    scopus 로고
    • Altered histone acetylation is associated with age-dependent memory impairment in mice
    • Peleg S, Sananbenesi F, Zovoilis A, et al. 2010. Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 328: 753-756.
    • (2010) Science , vol.328 , pp. 753-756
    • Peleg, S.1    Sananbenesi, F.2    Zovoilis, A.3
  • 79
    • 80052560599 scopus 로고    scopus 로고
    • Age-related changes in Arc transcription and DNA methylation within the hippocampus
    • Penner MR, Roth TL, Chawla MK, et al. 2011. Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol Aging 32: 2198-2210.
    • (2011) Neurobiol Aging , vol.32 , pp. 2198-2210
    • Penner, M.R.1    Roth, T.L.2    Chawla, M.K.3
  • 80
    • 84891783936 scopus 로고    scopus 로고
    • Childhood maltreatment and methylation of the glucocorticoid receptor gene NR3C1 in bipolar disorder
    • Perroud N, Dayer A, Piguet C, et al. 2014. Childhood maltreatment and methylation of the glucocorticoid receptor gene NR3C1 in bipolar disorder. Br J Psychiatry 204: 30-35.
    • (2014) Br J Psychiatry , vol.204 , pp. 30-35
    • Perroud, N.1    Dayer, A.2    Piguet, C.3
  • 82
    • 84876181160 scopus 로고    scopus 로고
    • Targeting specific HATs for neurodegenerative disease treatment: Translating basic biology to therapeutic possibilities
    • Pirooznia SK, Elefant F. 2013. Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities. Front Cell Neurosci 7: 30.
    • (2013) Front Cell Neurosci , vol.7 , pp. 30
    • Pirooznia, S.K.1    Elefant, F.2
  • 83
    • 84864126183 scopus 로고    scopus 로고
    • Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
    • Qureshi IA, Mehler MF. 2012. Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. Nat Rev Neurosci 13: 528-541.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 528-541
    • Qureshi, I.A.1    Mehler, M.F.2
  • 84
    • 33947534891 scopus 로고    scopus 로고
    • Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
    • Rowe WB, Blalock EM, Chen KC, et al. 2007. Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci 27: 3098-3110.
    • (2007) J Neurosci , vol.27 , pp. 3098-3110
    • Rowe, W.B.1    Blalock, E.M.2    Chen, K.C.3
  • 86
    • 84855991876 scopus 로고    scopus 로고
    • Non-coding RNAs with essential roles in neurodegenerative disorders
    • Salta E, De Strooper B. 2012. Non-coding RNAs with essential roles in neurodegenerative disorders. Lancet Neurol 11: 189-200.
    • (2012) Lancet Neurol , vol.11 , pp. 189-200
    • Salta, E.1    De Strooper, B.2
  • 87
    • 66449104953 scopus 로고    scopus 로고
    • Epigenetic mechanisms in sequential differentiation of neural stem cells
    • Sanosaka T, Namihira M, Nakashima K. 2009. Epigenetic mechanisms in sequential differentiation of neural stem cells. Epigenetics 4: 89-92.
    • (2009) Epigenetics , vol.4 , pp. 89-92
    • Sanosaka, T.1    Namihira, M.2    Nakashima, K.3
  • 88
    • 84856692318 scopus 로고    scopus 로고
    • DNA methylation and cognitive functioning in healthy older adults
    • Schiepers OJ, Van Boxtel MP, De Groot RH, et al. 2012. DNA methylation and cognitive functioning in healthy older adults. Br J Nutr 107: 744-748.
    • (2012) Br J Nutr , vol.107 , pp. 744-748
    • Schiepers, O.J.1    Van Boxtel, M.P.2    De Groot, R.H.3
  • 89
    • 84875273571 scopus 로고    scopus 로고
    • Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders
    • Spadaro PA, Bredy TW. 2012. Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders. Front Genet 3: 132.
    • (2012) Front Genet , vol.3 , pp. 132
    • Spadaro, P.A.1    Bredy, T.W.2
  • 90
    • 79958001269 scopus 로고    scopus 로고
    • The role of histone acetylation in age-associated memory impairment and Alzheimer's disease
    • Stilling RM, Fischer A. 2011. The role of histone acetylation in age-associated memory impairment and Alzheimer's disease. Neurobiol Learn Mem 96: 19-26.
    • (2011) Neurobiol Learn Mem , vol.96 , pp. 19-26
    • Stilling, R.M.1    Fischer, A.2
  • 91
    • 84864475139 scopus 로고    scopus 로고
    • DNA methylation in cognition comes of age
    • Su SC, Tsai LH. 2012. DNA methylation in cognition comes of age. Nat Neurosci 15: 1061-1062.
    • (2012) Nat Neurosci , vol.15 , pp. 1061-1062
    • Su, S.C.1    Tsai, L.H.2
  • 92
    • 84886304753 scopus 로고    scopus 로고
    • Epigenetics of Alzheimer's disease and frontotemporal dementia
    • Veerappan CS, Sleiman S, Coppola G. 2013. Epigenetics of Alzheimer's disease and frontotemporal dementia. Neurotherapeutics 10: 709-721.
    • (2013) Neurotherapeutics , vol.10 , pp. 709-721
    • Veerappan, C.S.1    Sleiman, S.2    Coppola, G.3
  • 93
    • 84888197384 scopus 로고    scopus 로고
    • Epigenetic mechanisms in Alzheimer's disease: Implications for pathogenesis and therapy
    • Wang J, Yu JT, Tan MS, Jiang T, Tan L. 2013. Epigenetic mechanisms in Alzheimer's disease: implications for pathogenesis and therapy. Ageing Res Rev 12: 1024-1041.
    • (2013) Ageing Res Rev , vol.12 , pp. 1024-1041
    • Wang, J.1    Yu, J.T.2    Tan, M.S.3    Jiang, T.4    Tan, L.5
  • 94
    • 84892763878 scopus 로고    scopus 로고
    • Reversing DNA methylation: Mechanisms, genomics, and biological functions
    • Wu H, Zhang Y. 2014. Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell 156: 45-68.
    • (2014) Cell , vol.156 , pp. 45-68
    • Wu, H.1    Zhang, Y.2
  • 95
    • 38149024924 scopus 로고    scopus 로고
    • Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): Evidence for a developmental origin and environmental link for AD
    • Wu J, Basha MR, Brock B, et al. 2008. Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. J Neurosci 28: 3-9.
    • (2008) J Neurosci , vol.28 , pp. 3-9
    • Wu, J.1    Basha, M.R.2    Brock, B.3
  • 96
    • 84878990866 scopus 로고    scopus 로고
    • Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway
    • Zhao YN, Li WF, Li F, et al. 2013. Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway. Biochem Biophys Res Commun 435: 597-602.
    • (2013) Biochem Biophys Res Commun , vol.435 , pp. 597-602
    • Zhao, Y.N.1    Li, W.F.2    Li, F.3
  • 97
    • 78650304236 scopus 로고    scopus 로고
    • Charting histone modifications and the functional organization of mammalian genomes
    • Zhou VW, Goren A, Bernstein BE. 2011. Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet 12: 7-18.
    • (2011) Nat Rev Genet , vol.12 , pp. 7-18
    • Zhou, V.W.1    Goren, A.2    Bernstein, B.E.3
  • 98
    • 84874076991 scopus 로고    scopus 로고
    • Epigenetic regulation of memory formation and maintenance
    • Zovkic IB, Guzman-Karlsson MC, Sweatt JD. 2013. Epigenetic regulation of memory formation and maintenance. Learn Mem 20: 61-74.
    • (2013) Learn Mem , vol.20 , pp. 61-74
    • Zovkic, I.B.1    Guzman-Karlsson, M.C.2    Sweatt, J.D.3
  • 99
    • 80054935981 scopus 로고    scopus 로고
    • MicroRNA-34c is a novel target to treat dementias
    • Zovoilis A, Agbemenyah HY, Agis-Balboa RC, et al. 2011. MicroRNA-34c is a novel target to treat dementias. EMBO J 30: 4299-4308.
    • (2011) EMBO J , vol.30 , pp. 4299-4308
    • Zovoilis, A.1    Agbemenyah, H.Y.2    Agis-Balboa, R.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.