-
1
-
-
42749087468
-
Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability
-
Adams M.M., Shi L., Linville M.C., Forbes M.E., Long A.B., Bennett C., Newton I.G., Carter C.S., Sonntag W.E., Riddle D.R., Brunso-Bechtold J.K. Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability. Exp. Neurol. 2008, 211:141-149.
-
(2008)
Exp. Neurol.
, vol.211
, pp. 141-149
-
-
Adams, M.M.1
Shi, L.2
Linville, M.C.3
Forbes, M.E.4
Long, A.B.5
Bennett, C.6
Newton, I.G.7
Carter, C.S.8
Sonntag, W.E.9
Riddle, D.R.10
Brunso-Bechtold, J.K.11
-
3
-
-
77954679759
-
Superoxide dismutase 1 knockdown induces oxidative stress and DNA methylation loss in the prostate
-
Bhusari S.S., Dobosy J.R., Fu V., Almassi N., Oberley T., Jarrard D.F. Superoxide dismutase 1 knockdown induces oxidative stress and DNA methylation loss in the prostate. Epigenetics 2010, 5.
-
(2010)
Epigenetics
, vol.5
-
-
Bhusari, S.S.1
Dobosy, J.R.2
Fu, V.3
Almassi, N.4
Oberley, T.5
Jarrard, D.F.6
-
4
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G., Guarente L. The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 2004, 73:417-435.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
5
-
-
57049106701
-
Differential MRI patterns of brain atrophy in double or single transgenic mice for APP and/or SOD
-
Borg J., Chereul E. Differential MRI patterns of brain atrophy in double or single transgenic mice for APP and/or SOD. J. Neurosci. Res. 2008, 86:3275-3284.
-
(2008)
J. Neurosci. Res.
, vol.86
, pp. 3275-3284
-
-
Borg, J.1
Chereul, E.2
-
6
-
-
0037107997
-
Copper/zinc superoxide dismutase overexpression promotes survival of cortical neurons exposed to neurotoxins in vitro
-
Borg J., London J. Copper/zinc superoxide dismutase overexpression promotes survival of cortical neurons exposed to neurotoxins in vitro. J. Neurosci. Res. 2002, 70:180-189.
-
(2002)
J. Neurosci. Res.
, vol.70
, pp. 180-189
-
-
Borg, J.1
London, J.2
-
7
-
-
45049086037
-
Regional-specific global cytosine methylation and DNA methyltransferase expression in the adult rat hippocampus
-
Brown S.E., Weaver I.C., Meaney M.J., Szyf M. Regional-specific global cytosine methylation and DNA methyltransferase expression in the adult rat hippocampus. Neurosci. Lett. 2008, 440:49-53.
-
(2008)
Neurosci. Lett.
, vol.440
, pp. 49-53
-
-
Brown, S.E.1
Weaver, I.C.2
Meaney, M.J.3
Szyf, M.4
-
8
-
-
77649305060
-
Senescent synapses and hippocampal circuit dynamics
-
Burke S.N., Barnes C.A. Senescent synapses and hippocampal circuit dynamics. Trends Neurosci. 2010, 33:153-161.
-
(2010)
Trends Neurosci.
, vol.33
, pp. 153-161
-
-
Burke, S.N.1
Barnes, C.A.2
-
9
-
-
0027972286
-
Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice
-
Cadet J.L., Sheng P., Ali S., Rothman R., Carlson E., Epstein C. Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice. J. Neurochem. 1994, 62:380-383.
-
(1994)
J. Neurochem.
, vol.62
, pp. 380-383
-
-
Cadet, J.L.1
Sheng, P.2
Ali, S.3
Rothman, R.4
Carlson, E.5
Epstein, C.6
-
10
-
-
68149100569
-
The role of epigenetics in aging and age-related diseases
-
Calvanese V., Lara E., Kahn A., Fraga M.F. The role of epigenetics in aging and age-related diseases. Ageing Res. Rev. 2009, 8:268-276.
-
(2009)
Ageing Res. Rev.
, vol.8
, pp. 268-276
-
-
Calvanese, V.1
Lara, E.2
Kahn, A.3
Fraga, M.F.4
-
11
-
-
0031705467
-
Attenuation of age-dependent oxidative damage to DNA and protein in brainstem of Tg Cu/Zn SOD mice
-
Cardozo-Pelaez F., Song S., Parthasarathy A., Epstein C.J., Sanchez-Ramos J. Attenuation of age-dependent oxidative damage to DNA and protein in brainstem of Tg Cu/Zn SOD mice. Neurobiol. Aging 1998, 19:311-316.
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 311-316
-
-
Cardozo-Pelaez, F.1
Song, S.2
Parthasarathy, A.3
Epstein, C.J.4
Sanchez-Ramos, J.5
-
12
-
-
0028567070
-
The role of the cellular antioxidant defense in oxidant carcinogenesis
-
Cerutti P., Ghosh R., Oya Y., Amstad P. The role of the cellular antioxidant defense in oxidant carcinogenesis. Environ. Health Perspect. 1994, 102(Suppl. 10):123-129.
-
(1994)
Environ. Health Perspect.
, vol.102
, Issue.SUPPL. 10
, pp. 123-129
-
-
Cerutti, P.1
Ghosh, R.2
Oya, Y.3
Amstad, P.4
-
13
-
-
0028661078
-
SOD-1 transgenic mice as a model for studies of neuroprotection in stroke and brain trauma
-
Chan P.H., Epstein C.J., Kinouchi H., Kamii H., Imaizumi S., Yang G., Chen S.F., Gafni J., Carlson E. SOD-1 transgenic mice as a model for studies of neuroprotection in stroke and brain trauma. Ann. NY Acad. Sci. 1994, 738:93-103.
-
(1994)
Ann. NY Acad. Sci.
, vol.738
, pp. 93-103
-
-
Chan, P.H.1
Epstein, C.J.2
Kinouchi, H.3
Kamii, H.4
Imaizumi, S.5
Yang, G.6
Chen, S.F.7
Gafni, J.8
Carlson, E.9
-
14
-
-
77950866465
-
Epigenetic regulation in the pathophysiology of Alzheimer's disease
-
Chouliaras L., Rutten B.P., Kenis G., Peerbooms O., Visser P.J., Verhey F., van Os J., Steinbusch H.W., van den Hove D.L. Epigenetic regulation in the pathophysiology of Alzheimer's disease. Prog. Neurobiol. 2010, 90:498-510.
-
(2010)
Prog. Neurobiol.
, vol.90
, pp. 498-510
-
-
Chouliaras, L.1
Rutten, B.P.2
Kenis, G.3
Peerbooms, O.4
Visser, P.J.5
Verhey, F.6
van Os, J.7
Steinbusch, H.W.8
van den Hove, D.L.9
-
15
-
-
78349273286
-
-
b. Gene-environment interaction research and transgenic mouse models of Alzheimer's disease.
-
Chouliaras, L., Sierksma, A.S., Kenis, G., Prickaerts, J., Lemmens, M.A., Brasnjevic, I., van Donkelaar, E.L., Martinez-Martinez, P., Losen, M., De Baets, M.H., Kholod, N., van Leeuwen, F., Hof, P.R., van Os, J., Steinbusch, H.W., van den Hove, D.L., Rutten, B.P., 2010b. Gene-environment interaction research and transgenic mouse models of Alzheimer's disease. Int. J. Alzheimers Dis.
-
(2010)
-
-
Chouliaras, L.1
Sierksma, A.S.2
Kenis, G.3
Prickaerts, J.4
Lemmens, M.A.5
Brasnjevic, I.6
van Donkelaar, E.L.7
Martinez-Martinez, P.8
Losen, M.9
De Baets, M.H.10
Kholod, N.11
van Leeuwen, F.12
Hof, P.R.13
van Os, J.14
Steinbusch, H.W.15
van den Hove, D.L.16
Rutten, B.P.17
-
16
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
Colman R.J., Anderson R.M., Johnson S.C., Kastman E.K., Kosmatka K.J., Beasley T.M., Allison D.B., Cruzen C., Simmons H.A., Kemnitz J.W., Weindruch R. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 2009, 325:201-204.
-
(2009)
Science
, vol.325
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
Kastman, E.K.4
Kosmatka, K.J.5
Beasley, T.M.6
Allison, D.B.7
Cruzen, C.8
Simmons, H.A.9
Kemnitz, J.W.10
Weindruch, R.11
-
17
-
-
0038799736
-
Oxidative DNA damage: mechanisms, mutation, and disease
-
Cooke M.S., Evans M.D., Dizdaroglu M., Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 2003, 17:1195-1214.
-
(2003)
FASEB J.
, vol.17
, pp. 1195-1214
-
-
Cooke, M.S.1
Evans, M.D.2
Dizdaroglu, M.3
Lunec, J.4
-
18
-
-
7244221348
-
DNA methylation, cancer susceptibility, and nutrient interactions
-
Davis C.D., Uthus E.O. DNA methylation, cancer susceptibility, and nutrient interactions. Exp. Biol. Med. (Maywood) 2004, 229:988-995.
-
(2004)
Exp. Biol. Med. (Maywood)
, vol.229
, pp. 988-995
-
-
Davis, C.D.1
Uthus, E.O.2
-
19
-
-
0037221445
-
Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases
-
Denu J.M. Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases. Trends Biochem. Sci. 2003, 28:41-48.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 41-48
-
-
Denu, J.M.1
-
20
-
-
77955043040
-
Dietary antioxidants and long-term risk of dementia
-
Devore E.E., Grodstein F., van Rooij F.J., Hofman A., Stampfer M.J., Witteman J.C., Breteler M.M. Dietary antioxidants and long-term risk of dementia. Arch. Neurol. 2010, 67:819-825.
-
(2010)
Arch. Neurol.
, vol.67
, pp. 819-825
-
-
Devore, E.E.1
Grodstein, F.2
van Rooij, F.J.3
Hofman, A.4
Stampfer, M.J.5
Witteman, J.C.6
Breteler, M.M.7
-
21
-
-
34249025187
-
Changes in the structural complexity of the aged brain
-
Dickstein D.L., Kabaso D., Rocher A.B., Luebke J.I., Wearne S.L., Hof P.R. Changes in the structural complexity of the aged brain. Aging Cell 2007, 6:275-284.
-
(2007)
Aging Cell
, vol.6
, pp. 275-284
-
-
Dickstein, D.L.1
Kabaso, D.2
Rocher, A.B.3
Luebke, J.I.4
Wearne, S.L.5
Hof, P.R.6
-
22
-
-
34547558211
-
Medicine. The yin-yang of sirtuins
-
Dillin A., Kelly J.W. Medicine. The yin-yang of sirtuins. Science 2007, 317:461-462.
-
(2007)
Science
, vol.317
, pp. 461-462
-
-
Dillin, A.1
Kelly, J.W.2
-
23
-
-
34248370579
-
Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters
-
Dong E., Guidotti A., Grayson D.R., Costa E. Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters. Proc. Natl. Acad. Sci. USA 2007, 104:4676-4681.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4676-4681
-
-
Dong, E.1
Guidotti, A.2
Grayson, D.R.3
Costa, E.4
-
24
-
-
0032439246
-
Nutrition, cancer, and aging
-
Dreosti I.E. Nutrition, cancer, and aging. Ann. NY Acad. Sci. 1998, 854:371-377.
-
(1998)
Ann. NY Acad. Sci.
, vol.854
, pp. 371-377
-
-
Dreosti, I.E.1
-
25
-
-
77649247703
-
5-Lipoxygenase DNA methylation and mRNA content in the brain and heart of young and old mice
-
Dzitoyeva S., Imbesi M., Ng L.W., Manev H. 5-Lipoxygenase DNA methylation and mRNA content in the brain and heart of young and old mice. Neural. Plast. 2009, 2009:209596.
-
(2009)
Neural. Plast.
, vol.2009
, pp. 209596
-
-
Dzitoyeva, S.1
Imbesi, M.2
Ng, L.W.3
Manev, H.4
-
26
-
-
0023444192
-
Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome
-
Epstein C.J., Avraham K.B., Lovett M., Smith S., Elroy-Stein O., Rotman G., Bry C., Groner Y. Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome. Proc. Natl. Acad. Sci. USA 1987, 84:8044-8048.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8044-8048
-
-
Epstein, C.J.1
Avraham, K.B.2
Lovett, M.3
Smith, S.4
Elroy-Stein, O.5
Rotman, G.6
Bry, C.7
Groner, Y.8
-
27
-
-
77952518769
-
Folate, DNA damage and the aging brain
-
Fenech M. Folate, DNA damage and the aging brain. Mech. Ageing Dev. 2010, 131:236-241.
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 236-241
-
-
Fenech, M.1
-
28
-
-
16444381345
-
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
-
Feng J., Chang H., Li E., Fan G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J. Neurosci. Res. 2005, 79:734-746.
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 734-746
-
-
Feng, J.1
Chang, H.2
Li, E.3
Fan, G.4
-
29
-
-
71749084889
-
The role of DNA methylation in the central nervous system and neuropsychiatric disorders
-
Feng J., Fan G. The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int. Rev. Neurobiol. 2009, 89:67-84.
-
(2009)
Int. Rev. Neurobiol.
, vol.89
, pp. 67-84
-
-
Feng, J.1
Fan, G.2
-
30
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
-
Feng J., Zhou Y., Campbell S.L., Le T., Li E., Sweatt J.D., Silva A.J., Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 2010, 13:423-430.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
Le, T.4
Li, E.5
Sweatt, J.D.6
Silva, A.J.7
Fan, G.8
-
31
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T., Deng C.X., Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 2009, 460:587-591.
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
32
-
-
77951176737
-
Extending healthy life span - from yeast to humans
-
Fontana L., Partridge L., Longo V.D. Extending healthy life span - from yeast to humans. Science 2010, 328:321-326.
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
33
-
-
34447625911
-
Epigenetics and aging: the targets and the marks
-
Fraga M.F., Esteller M. Epigenetics and aging: the targets and the marks. Trends Genet. 2007, 23:413-418.
-
(2007)
Trends Genet.
, vol.23
, pp. 413-418
-
-
Fraga, M.F.1
Esteller, M.2
-
35
-
-
0023760665
-
The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
-
Gundersen H.J., Bagger P., Bendtsen T.F., Evans S.M., Korbo L., Marcussen N., Moller A., Nielsen K., Nyengaard J.R., Pakkenberg B., et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 1988, 96:857-881.
-
(1988)
APMIS
, vol.96
, pp. 857-881
-
-
Gundersen, H.J.1
Bagger, P.2
Bendtsen, T.F.3
Evans, S.M.4
Korbo, L.5
Marcussen, N.6
Moller, A.7
Nielsen, K.8
Nyengaard, J.R.9
Pakkenberg, B.10
-
36
-
-
79954878456
-
-
Prominent hippocampal CA3 gene expression profile in neurocognitive aging. Neurobiol. Aging.
-
Haberman, R.P., Colantuoni, C., Stocker, A.M., Schmidt, A.C., Pedersen, J.T., Gallagher, M., 2009. Prominent hippocampal CA3 gene expression profile in neurocognitive aging. Neurobiol. Aging.
-
(2009)
-
-
Haberman, R.P.1
Colantuoni, C.2
Stocker, A.M.3
Schmidt, A.C.4
Pedersen, J.T.5
Gallagher, M.6
-
37
-
-
67649656314
-
Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver
-
Hagopian K., Ramsey J.J., Weindruch R. Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver. Biogerontology 2009, 10:471-479.
-
(2009)
Biogerontology
, vol.10
, pp. 471-479
-
-
Hagopian, K.1
Ramsey, J.J.2
Weindruch, R.3
-
38
-
-
0027745794
-
Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro
-
Hass B.S., Hart R.W., Lu M.H., Lyn-Cook B.D. Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro. Mutat. Res. 1993, 295:281-289.
-
(1993)
Mutat. Res.
, vol.295
, pp. 281-289
-
-
Hass, B.S.1
Hart, R.W.2
Lu, M.H.3
Lyn-Cook, B.D.4
-
39
-
-
4544322402
-
The aging brain: morphomolecular senescence of cortical circuits
-
Hof P.R., Morrison J.H. The aging brain: morphomolecular senescence of cortical circuits. Trends Neurosci. 2004, 27:607-613.
-
(2004)
Trends Neurosci.
, vol.27
, pp. 607-613
-
-
Hof, P.R.1
Morrison, J.H.2
-
40
-
-
70449523239
-
5-Lipoxygenase and epigenetic DNA methylation in aging cultures of cerebellar granule cells
-
Imbesi M., Dzitoyeva S., Ng L.W., Manev H. 5-Lipoxygenase and epigenetic DNA methylation in aging cultures of cerebellar granule cells. Neuroscience 2009, 164:1531-1537.
-
(2009)
Neuroscience
, vol.164
, pp. 1531-1537
-
-
Imbesi, M.1
Dzitoyeva, S.2
Ng, L.W.3
Manev, H.4
-
41
-
-
70350482460
-
Nutrition, brain aging, and neurodegeneration
-
Joseph J., Cole G., Head E., Ingram D. Nutrition, brain aging, and neurodegeneration. J. Neurosci. 2009, 29:12795-12801.
-
(2009)
J. Neurosci.
, vol.29
, pp. 12795-12801
-
-
Joseph, J.1
Cole, G.2
Head, E.3
Ingram, D.4
-
42
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim D., Nguyen M.D., Dobbin M.M., Fischer A., Sananbenesi F., Rodgers J.T., Delalle I., Baur J.A., Sui G., Armour S.M., Puigserver P., Sinclair D.A., Tsai L.H. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 2007, 26:3169-3179.
-
(2007)
EMBO J.
, vol.26
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
Delalle, I.7
Baur, J.A.8
Sui, G.9
Armour, S.M.10
Puigserver, P.11
Sinclair, D.A.12
Tsai, L.H.13
-
43
-
-
0042318773
-
Roles of histone acetylation in the Dnmt1 gene expression
-
Kishikawa S., Ugai H., Murata T., Yokoyama K.K. Roles of histone acetylation in the Dnmt1 gene expression. Nucleic Acids Res. Suppl. 2002, 209:210.
-
(2002)
Nucleic Acids Res. Suppl.
, vol.209
, pp. 210
-
-
Kishikawa, S.1
Ugai, H.2
Murata, T.3
Yokoyama, K.K.4
-
44
-
-
33947115405
-
Volume, neuron density and total neuron number in five subcortical regions in schizophrenia
-
Kreczmanski P., Heinsen H., Mantua V., Woltersdorf F., Masson T., Ulfig N., Schmidt-Kastner R., Korr H., Steinbusch H.W., Hof P.R., Schmitz C. Volume, neuron density and total neuron number in five subcortical regions in schizophrenia. Brain 2007, 130:678-692.
-
(2007)
Brain
, vol.130
, pp. 678-692
-
-
Kreczmanski, P.1
Heinsen, H.2
Mantua, V.3
Woltersdorf, F.4
Masson, T.5
Ulfig, N.6
Schmidt-Kastner, R.7
Korr, H.8
Steinbusch, H.W.9
Hof, P.R.10
Schmitz, C.11
-
45
-
-
0029863342
-
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation
-
Kuhn H.G., Dickinson-Anson H., Gage F.H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 1996, 16:2027-2033.
-
(1996)
J. Neurosci.
, vol.16
, pp. 2027-2033
-
-
Kuhn, H.G.1
Dickinson-Anson, H.2
Gage, F.H.3
-
46
-
-
38449086171
-
Eat less, live longer? New insights into the role of caloric restriction in the brain
-
Levenson C.W., Rich N.J. Eat less, live longer? New insights into the role of caloric restriction in the brain. Nutr. Rev. 2007, 65:412-415.
-
(2007)
Nutr. Rev.
, vol.65
, pp. 412-415
-
-
Levenson, C.W.1
Rich, N.J.2
-
47
-
-
77954600272
-
Vitamin D and risk of cognitive decline in elderly persons
-
Llewellyn D.J., Lang I.A., Langa K.M., Muniz-Terrera G., Phillips C.L., Cherubini A., Ferrucci L., Melzer D. Vitamin D and risk of cognitive decline in elderly persons. Arch. Intern. Med. 2010, 170:1135-1141.
-
(2010)
Arch. Intern. Med.
, vol.170
, pp. 1135-1141
-
-
Llewellyn, D.J.1
Lang, I.A.2
Langa, K.M.3
Muniz-Terrera, G.4
Phillips, C.L.5
Cherubini, A.6
Ferrucci, L.7
Melzer, D.8
-
48
-
-
41149167542
-
Orexin signaling mediates the antidepressant-like effect of calorie restriction
-
Lutter M., Krishnan V., Russo S.J., Jung S., McClung C.A., Nestler E.J. Orexin signaling mediates the antidepressant-like effect of calorie restriction. J. Neurosci. 2008, 28:3071-3075.
-
(2008)
J. Neurosci.
, vol.28
, pp. 3071-3075
-
-
Lutter, M.1
Krishnan, V.2
Russo, S.J.3
Jung, S.4
McClung, C.A.5
Nestler, E.J.6
-
49
-
-
67349204386
-
Epigenetic regulation of nervous system development by DNA methylation and histone deacetylation
-
MacDonald J.L., Roskams A.J. Epigenetic regulation of nervous system development by DNA methylation and histone deacetylation. Prog. Neurobiol. 2009, 88:170-183.
-
(2009)
Prog. Neurobiol.
, vol.88
, pp. 170-183
-
-
MacDonald, J.L.1
Roskams, A.J.2
-
50
-
-
0036304650
-
Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior
-
Mattson M.P., Chan S.L., Duan W. Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior. Physiol. Rev. 2002, 82:637-672.
-
(2002)
Physiol. Rev.
, vol.82
, pp. 637-672
-
-
Mattson, M.P.1
Chan, S.L.2
Duan, W.3
-
51
-
-
0036752830
-
Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior
-
Mattson M.P., Duan W., Chan S.L., Cheng A., Haughey N., Gary D.S., Guo Z., Lee J., Furukawa K. Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior. Neurobiol. Aging 2002, 23:695-705.
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 695-705
-
-
Mattson, M.P.1
Duan, W.2
Chan, S.L.3
Cheng, A.4
Haughey, N.5
Gary, D.S.6
Guo, Z.7
Lee, J.8
Furukawa, K.9
-
52
-
-
61649106707
-
Environmental-induced oxidative stress in neurodegenerative disorders and aging
-
Migliore L., Coppede F. Environmental-induced oxidative stress in neurodegenerative disorders and aging. Mutat. Res. 2009, 674:73-84.
-
(2009)
Mutat. Res.
, vol.674
, pp. 73-84
-
-
Migliore, L.1
Coppede, F.2
-
53
-
-
33847614418
-
Covalent modification of DNA regulates memory formation
-
Miller C.A., Sweatt J.D. Covalent modification of DNA regulates memory formation. Neuron 2007, 53:857-869.
-
(2007)
Neuron
, vol.53
, pp. 857-869
-
-
Miller, C.A.1
Sweatt, J.D.2
-
54
-
-
0036837646
-
Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress
-
Miura H., Qiao H., Ohta T. Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress. Synapse 2002, 46:116-124.
-
(2002)
Synapse
, vol.46
, pp. 116-124
-
-
Miura, H.1
Qiao, H.2
Ohta, T.3
-
55
-
-
70149092727
-
Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice
-
Mouton P.R., Chachich M.E., Quigley C., Spangler E., Ingram D.K. Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice. Neurosci. Lett. 2009, 464:184-187.
-
(2009)
Neurosci. Lett.
, vol.464
, pp. 184-187
-
-
Mouton, P.R.1
Chachich, M.E.2
Quigley, C.3
Spangler, E.4
Ingram, D.K.5
-
56
-
-
34250643467
-
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
-
Nguyen S., Meletis K., Fu D., Jhaveri S., Jaenisch R. Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Dev. Dyn. 2007, 236:1663-1676.
-
(2007)
Dev. Dyn.
, vol.236
, pp. 1663-1676
-
-
Nguyen, S.1
Meletis, K.2
Fu, D.3
Jhaveri, S.4
Jaenisch, R.5
-
57
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M., Bell D.W., Haber D.A., Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
58
-
-
34547599329
-
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
-
Outeiro T.F., Kontopoulos E., Altmann S.M., Kufareva I., Strathearn K.E., Amore A.M., Volk C.B., Maxwell M.M., Rochet J.C., McLean P.J., Young A.B., Abagyan R., Feany M.B., Hyman B.T., Kazantsev A.G. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science 2007, 317:516-519.
-
(2007)
Science
, vol.317
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
Volk, C.B.7
Maxwell, M.M.8
Rochet, J.C.9
McLean, P.J.10
Young, A.B.11
Abagyan, R.12
Feany, M.B.13
Hyman, B.T.14
Kazantsev, A.G.15
-
59
-
-
14644421534
-
Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models
-
Patel N.V., Gordon M.N., Connor K.E., Good R.A., Engelman R.W., Mason J., Morgan D.G., Morgan T.E., Finch C.E. Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models. Neurobiol. Aging 2005, 26:995-1000.
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 995-1000
-
-
Patel, N.V.1
Gordon, M.N.2
Connor, K.E.3
Good, R.A.4
Engelman, R.W.5
Mason, J.6
Morgan, D.G.7
Morgan, T.E.8
Finch, C.E.9
-
60
-
-
79954867433
-
-
Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol. Aging.
-
Penner, M.R., Roth, T.L., Chawla, M.K., Hoang, L.T., Roth, E.D., Lubin, F.D., Sweatt, J.D., Worley, P.F., Barnes, C.A., 2010. Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol. Aging.
-
(2010)
-
-
Penner, M.R.1
Roth, T.L.2
Chawla, M.K.3
Hoang, L.T.4
Roth, E.D.5
Lubin, F.D.6
Sweatt, J.D.7
Worley, P.F.8
Barnes, C.A.9
-
61
-
-
12844271254
-
The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension
-
Porcu M., Chiarugi A. The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension. Trends Pharmacol. Sci. 2005, 26:94-103.
-
(2005)
Trends Pharmacol. Sci.
, vol.26
, pp. 94-103
-
-
Porcu, M.1
Chiarugi, A.2
-
62
-
-
0026629397
-
Superoxide dismutase, catalase, and glutathione peroxidase activities in copper/zinc-superoxide dismutase transgenic mice
-
Przedborski S., Jackson-Lewis V., Kostic V., Carlson E., Epstein C.J., Cadet J.L. Superoxide dismutase, catalase, and glutathione peroxidase activities in copper/zinc-superoxide dismutase transgenic mice. J. Neurochem. 1992, 58:1760-1767.
-
(1992)
J. Neurochem.
, vol.58
, pp. 1760-1767
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Kostic, V.3
Carlson, E.4
Epstein, C.J.5
Cadet, J.L.6
-
63
-
-
51249104026
-
Pro-oxidant shift in glutathione redox state during aging
-
Rebrin I., Sohal R.S. Pro-oxidant shift in glutathione redox state during aging. Adv. Drug Deliv. Rev. 2008, 60:1545-1552.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 1545-1552
-
-
Rebrin, I.1
Sohal, R.S.2
-
64
-
-
77957294445
-
Caloric restriction and aging but not overexpression of SOD1 affect hippocampal volumes in mice
-
Rutten B.P., Brasnjevic I., Steinbusch H.W., Schmitz C. Caloric restriction and aging but not overexpression of SOD1 affect hippocampal volumes in mice. Mech. Ageing Dev. 2010, 131:574-579.
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 574-579
-
-
Rutten, B.P.1
Brasnjevic, I.2
Steinbusch, H.W.3
Schmitz, C.4
-
65
-
-
0037341485
-
The aging brain: less neurons could be better
-
Rutten B.P., Korr H., Steinbusch H.W., Schmitz C. The aging brain: less neurons could be better. Mech. Ageing Dev. 2003, 124:349-355.
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 349-355
-
-
Rutten, B.P.1
Korr, H.2
Steinbusch, H.W.3
Schmitz, C.4
-
66
-
-
33751214500
-
The aging brain: accumulation of DNA damage or neuron loss?
-
Rutten B.P., Schmitz C., Gerlach O.H., Oyen H.M., de Mesquita E.B., Steinbusch H.W., Korr H. The aging brain: accumulation of DNA damage or neuron loss?. Neurobiol. Aging 2007, 28:91-98.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 91-98
-
-
Rutten, B.P.1
Schmitz, C.2
Gerlach, O.H.3
Oyen, H.M.4
de Mesquita, E.B.5
Steinbusch, H.W.6
Korr, H.7
-
67
-
-
0141617733
-
Antioxidants and Alzheimer's disease: from bench to bedside (and back again)
-
Rutten B.P., Steinbusch H.W., Korr H., Schmitz C. Antioxidants and Alzheimer's disease: from bench to bedside (and back again). Curr. Opin. Clin. Nutr. Metab. Care 2002, 5:645-651.
-
(2002)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.5
, pp. 645-651
-
-
Rutten, B.P.1
Steinbusch, H.W.2
Korr, H.3
Schmitz, C.4
-
68
-
-
0033042975
-
Age-related changes of DNA repair and mitochondrial DNA synthesis in the mouse brain
-
Schmitz C., Axmacher B., Zunker U., Korr H. Age-related changes of DNA repair and mitochondrial DNA synthesis in the mouse brain. Acta Neuropathol. 1999, 97:71-81.
-
(1999)
Acta Neuropathol.
, vol.97
, pp. 71-81
-
-
Schmitz, C.1
Axmacher, B.2
Zunker, U.3
Korr, H.4
-
69
-
-
0033789892
-
Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach
-
Schmitz C., Hof P.R. Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach. J. Chem. Neuroanat. 2000, 20:93-114.
-
(2000)
J. Chem. Neuroanat.
, vol.20
, pp. 93-114
-
-
Schmitz, C.1
Hof, P.R.2
-
70
-
-
11844300345
-
Design-based stereology in neuroscience
-
Schmitz C., Hof P.R. Design-based stereology in neuroscience. Neuroscience 2005, 130:813-831.
-
(2005)
Neuroscience
, vol.130
, pp. 813-831
-
-
Schmitz, C.1
Hof, P.R.2
-
71
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner S.E., Linford N.J., Martin G.M., Treuting P., Ogburn C.E., Emond M., Coskun P.E., Ladiges W., Wolf N., Van Remmen H., Wallace D.C., Rabinovitch P.S. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 2005, 308:1909-1911.
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
Coskun, P.E.7
Ladiges, W.8
Wolf, N.9
Van Remmen, H.10
Wallace, D.C.11
Rabinovitch, P.S.12
-
72
-
-
0034895953
-
Overexpression of copper/zinc-superoxide dismutase protects from kanamycin-induced hearing loss
-
Sha S.H., Zajic G., Epstein C.J., Schacht J. Overexpression of copper/zinc-superoxide dismutase protects from kanamycin-induced hearing loss. Audiol. Neurootol. 2001, 6:117-123.
-
(2001)
Audiol. Neurootol.
, vol.6
, pp. 117-123
-
-
Sha, S.H.1
Zajic, G.2
Epstein, C.J.3
Schacht, J.4
-
73
-
-
41149090082
-
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
-
Siegmund K.D., Connor C.M., Campan M., Long T.I., Weisenberger D.J., Biniszkiewicz D., Jaenisch R., Laird P.W., Akbarian S. DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS One 2007, 2:e895.
-
(2007)
PLoS One
, vol.2
-
-
Siegmund, K.D.1
Connor, C.M.2
Campan, M.3
Long, T.I.4
Weisenberger, D.J.5
Biniszkiewicz, D.6
Jaenisch, R.7
Laird, P.W.8
Akbarian, S.9
-
74
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal R.S., Weindruch R. Oxidative stress, caloric restriction, and aging. Science 1996, 273:59-63.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
75
-
-
43649083732
-
A combined behavioral and morphological study on the effects of fetal asphyxia on the nigrostriatal dopaminergic system in adult rats
-
Strackx E., Van den Hove D.L., Steinbusch H.P., Steinbusch H.W., Vles J.S., Blanco C.E., Gavilanes A.W. A combined behavioral and morphological study on the effects of fetal asphyxia on the nigrostriatal dopaminergic system in adult rats. Exp. Neurol. 2008, 211:413-422.
-
(2008)
Exp. Neurol.
, vol.211
, pp. 413-422
-
-
Strackx, E.1
Van den Hove, D.L.2
Steinbusch, H.P.3
Steinbusch, H.W.4
Vles, J.S.5
Blanco, C.E.6
Gavilanes, A.W.7
-
76
-
-
57749122150
-
Effect of neural precursor proliferation level on neurogenesis in rat brain during aging and after focal ischemia
-
Tang H., Wang Y., Xie L., Mao X., Won S.J., Galvan V., Jin K. Effect of neural precursor proliferation level on neurogenesis in rat brain during aging and after focal ischemia. Neurobiol. Aging 2009, 30:299-308.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 299-308
-
-
Tang, H.1
Wang, Y.2
Xie, L.3
Mao, X.4
Won, S.J.5
Galvan, V.6
Jin, K.7
-
77
-
-
0022517746
-
The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake
-
Weindruch R., Walford R.L., Fligiel S., Guthrie D. The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J. Nutr. 1986, 116:641-654.
-
(1986)
J. Nutr.
, vol.116
, pp. 641-654
-
-
Weindruch, R.1
Walford, R.L.2
Fligiel, S.3
Guthrie, D.4
-
78
-
-
59049104610
-
Caloric restriction improves memory in elderly humans
-
Witte A.V., Fobker M., Gellner R., Knecht S., Floel A. Caloric restriction improves memory in elderly humans. Proc. Natl. Acad. Sci. USA 2009, 106:1255-1260.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1255-1260
-
-
Witte, A.V.1
Fobker, M.2
Gellner, R.3
Knecht, S.4
Floel, A.5
-
79
-
-
77954842322
-
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
-
Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y., Sun Y.E. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010, 329:444-448.
-
(2010)
Science
, vol.329
, pp. 444-448
-
-
Wu, H.1
Coskun, V.2
Tao, J.3
Xie, W.4
Ge, W.5
Yoshikawa, K.6
Li, E.7
Zhang, Y.8
Sun, Y.E.9
-
80
-
-
58149229589
-
The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life
-
Wu W., Brickman A.M., Luchsinger J., Ferrazzano P., Pichiule P., Yoshita M., Brown T., DeCarli C., Barnes C.A., Mayeux R., Vannucci S.J., Small S.A. The brain in the age of old: the hippocampal formation is targeted differentially by diseases of late life. Ann. Neurol. 2008, 64:698-706.
-
(2008)
Ann. Neurol.
, vol.64
, pp. 698-706
-
-
Wu, W.1
Brickman, A.M.2
Luchsinger, J.3
Ferrazzano, P.4
Pichiule, P.5
Yoshita, M.6
Brown, T.7
DeCarli, C.8
Barnes, C.A.9
Mayeux, R.10
Vannucci, S.J.11
Small, S.A.12
|