Homocysteine, depression and cognitive function in older adults

Journal of Affective Disorders

Volumn 151, Issue 2, 2013, Pages 646-651

  Ford, Andrew H ^a,b,c   Flicker, Leon ^a,d   Singh, Urvashnee ^c   Hirani, Varsha ^a,b   Almeida, Osvaldo P ^a,b,c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c ROYAL PERTH HOSPITAL   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Cognition; Depression; Homocysteine

Indexed keywords

HOMOCYSTEINE;

ADULT; AGED; ARTICLE; COGNITION; COGNITIVE DEFECT; DIET RESTRICTION; DSM-IV-TR; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MINI MENTAL STATE EXAMINATION; MONTGOMERY ASBERG DEPRESSION RATING SCALE; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; REGISTER; VISUAL MEMORY; WORD RECOGNITION;

COGNITION; DEPRESSION; HOMOCYSTEINE;

AGED; COGNITION DISORDERS; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER, MAJOR; FEMALE; HOMOCYSTEINE; HUMANS; MALE; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84885469979     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2013.07.012     Document Type: Article

References (50)

1. G.S. Alexopoulos, B.S. Meyers, R.C. Young, S. Campbell, D. Silbersweig, and M. Charlson 'Vascular depression' hypothesis Archives of General Psychiatry 54 10 1997 915 922
2. G.S. Alexopoulos, D.N. Kiosses, S. Klimstra, B. Kalayam, and M.L. Bruce Clinical presentation of the "depression-executive dysfunction syndrome" of late life American Journal of Geriatric Psychiatry 10 1 2002 98 106
3. P. Alexopoulos, S. Topalidis, G. Irmisch, K. Prehn, S.U. Jung, and K. Poppe Homocysteine and cognitive function in geriatric depression Neuropsychobiology 61 2 2010 97 104
4. O.P. Almeida, N. Lautenschlager, L. Flicker, P. Leedman, S. Vasikaran, and A. Gelavis Association between homocysteine, depression, and cognitive function in community-dwelling older women from Australia American Journal of Geriatric Psychiatry 52 2 2004 327 328
5. O.P. Almeida, K. McCaul, G.J. Hankey, P. Norman, K. Jamrozik, and L. Flicker Homocysteine and depression in later life Archives of General Psychiatry 65 11 2008 1286 1294
6. A. Araki, and Y. Sako Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection Journal of Chromatography 422 1987 43 52
7. A. Araki, T. Hosoi, H. Orimo, and H. Ito Association of plasma homocysteine with serum interleukin-6 and C-peptide levels in patients with type 2 diabetes Metabolism 54 6 2005 809 814
8. R.C. Baldwin Is vascular depression a distinct sub-type of depressive disorder? A review of causal evidence International Journal of Geriatric Psychiatry 20 1 2005 1 11
9. I.R. Bell, J.S. Edman, J. Selhub, F.D. Morrow, D.W. Marby, and H.L. Kayne Plasma homocysteine in vascular disease and in nonvascular dementia of depressed elderly people Acta Psychiatrica Scandinavica 86 5 1992 386 390
10. R.K. Bhalla, M.A. Butters, B.H. Mulsant, A.E. Begley, M.D. Zmuda, and B. Schoderbek Persistence of neuropsychologic deficits in the remitted state of late-life depression American Journal of Geriatric Psychiatry 14 5 2006 419 427
11. M.J. Bohn, T.F. Babor, and H.R. Kranzler The Alcohol Use Disorders Identification Test (AUDIT): validation of a screening instrument for use in medical settings Journal of Studies on Alcohol 56 4 1995 423 432
12. T. Bottiglieri Homocysteine and folate metabolism in depression Neuro-Psychopharmacology and Biological Psychiatry 29 7 2005 1103 1112
13. T. Bottiglieri, M. Laundy, R. Crellin, B.K. Toone, M.W. Carney, and E.H. Reynolds Homocysteine folate, methylation, and monoamine metabolism in depression Journal of Neurology, Neurosurgery, and Psychiatry 69 2 2000 228 232
14. G. Dal Forno, M.T. Palermo, J.E. Donohue, H. Karagiozis, A.B. Zonderman, and C.H. Kawas Depressive symptoms, sex, and risk for Alzheimer's disease Annals of Neurology 57 3 2005 381 387
15. S. Dayal, E. Arning, T. Bottiglieri, R.H. Boger, C.D. Sigmund, and F.M. Faraci Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice Stroke 35 8 2004 1957 1962
16. J. Durga, M.P. van Boxtel, E.G. Schouten, F.J. Kok, J. Jolles, and M.B. Katan Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial Lancet 369 9557 2007 208 216
17. V. Elderkin-Thompson, J. Mintz, E. Haroon, H. Lavretsky, and A. Kumar Executive dysfunction and memory in older patients with major and minor depression Archives of Clinical Neuropsychology 22 2 2007 261 270
18. M.F. Folstein, S.E. Folstein, and P.R. McHugh "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician Journal of Psychiatric Research 12 3 1975 189 198
19. A.H. Ford, and O.P. Almeida Effect of homocysteine lowering treatment on cognitive function: a systematic review and meta-analysis of randomized controlled trials Journal of Alzheimer's Disease 29 1 2012 133 149
20. A.H. Ford, L. Flicker, K. McCaul, F. van Bockxmeer, S. Hegarty, and V. Hirani The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life Trials 11 2010 8
21. A.H. Ford, L. Flicker, G.J. Hankey, P. Norman, F.M. van Bockxmeer, and O.P. Almeida Homocysteine methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study Molecular Psychiatry 17 5 2012 559 566
22. P. Forti, E. Rietti, N. Pisacane, V. Olivelli, E. Dalmonte, and P. Mecocci Blood homocysteine and risk of depression in the elderly Archives of Gerontology and Geriatrics 51 1 2010 21 25
23. R.C. Green, L.A. Cupples, A. Kurz, S. Auerbach, R. Go, and D. Sadovnick Depression as a risk factor for Alzheimer disease: the MIRAGE study Archives of Neurology 60 5 2003 753 759
24. G.J. Hankey, J.W. Eikelboom, W.K. Ho, and F.M. van Bockxmeer Clinical usefulness of plasma homocysteine in vascular disease Medical Journal of Australia 181 6 2004 314 318
25. N. Herrmann, A. Li, and K. Lanctot Memantine in dementia: a review of the current evidence Expert Opinion on Pharmacotherapy 12 5 2011 787 800
26. A.F. Jorm History of depression as a risk factor for dementia: an updated review Australian and New Zealand Journal of Psychiatry 35 6 2001 776 781
27. K. Kroenke, R.L. Spitzer, and J.B. Williams The PHQ-9: validity of a brief depression severity measure Journal of General Internal Medicine 16 9 2001 606 613
28. E. LaBarge, D. Edwards, and J.W. Knesevich Performance of normal elderly on the Boston Naming Test Brain and Language 27 2 1986 380 384
29. H. Lavretsky, L. Ercoli, P. Siddarth, S. Bookheimer, K. Miller, and G. Small Apolipoprotein epsilon4 allele status, depressive symptoms, and cognitive decline in middle-aged and elderly persons without dementia American Journal of Geriatric Psychiatry 11 6 2003 667 673
30. H.B. Lee, and C.G. Lyketsos Depression in Alzheimer's disease: heterogeneity and related issues Biological Psychiatry 54 3 2003 353 362
31. A.D. Lopez, C.D. Mathers, M. Ezzati, D.T. Jamison, and C.J. Murray Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data Lancet 367 9524 2006 1747 1757
32. Homocysteine Lowering Trialists' Collaboration Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials British Medical Journal 316 7135 1998 894 898
33. M. Maes, R. Yirmyia, J. Noraberg, S. Brene, J. Hibbeln, and G. Perini The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression Metabolic Brain Disease 24 1 2009 27 53
34. R. Mojtabai, and M. Olfson Cognitive deficits and the course of major depression in a cohort of middle-aged and older community-dwelling adults Journal of the American Geriatrics Society 52 7 2004 1060 1069
35. S.A. Montgomery, and M. Asberg A new depression scale designed to be sensitive to change British Journal of Psychiatry 134 1979 382 389
36. N. Rasgon, and L. Jarvik Insulin resistance, affective disorders, and Alzheimer's disease: review and hypothesis Journals of Gerontology Series A: Biological Sciences and Medical Sciences 59 2 2004 178 183 (discussion 184-192)
37. M. Reale, T. Brenner, N.H. Greig, N. Inestrosa, and D. Paleacu Neuroinflammation, AD, and dementia International Journal of Alzheimer's Disease 2010 2. 10.4061/2010/974026 (online open access journal) Article ID 974026
38. H. Refsum, A.D. Smith, P.M. Ueland, E. Nexo, R. Clarke, and J. McPartlin Facts and recommendations about total homocysteine determinations: an expert opinion Clinical Chemistry 50 1 2004 3 32
39. K. Ritchie, I. Carriere, C.W. Ritchie, C. Berr, S. Artero, and M.L. Ancelin Designing prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors British Medical Journal 341 2010 c3885
40. P.S. Sachdev, R.A. Parslow, O. Lux, C. Salonikas, W. Wen, and D. Naidoo Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample Psychological Medicine 35 4 2005 529 538
41. I. Schweitzer, V. Tuckwell, J. O'Brien, and D. Ames Is late onset depression a prodrome to dementia? International Journal of Geriatric Psychiatry 17 11 2002 997 1005
42. D.V. Sheehan, Y. Lecrubier, K.H. Sheehan, P. Amorim, J. Janavs, and E. Weiller The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 Journal of Clinical Psychiatry 59 Suppl. 20 1998 22 33 (quiz 34-57)
43. M. Sjogren, L. Minthon, U. Passant, K. Blennow, and A. Wallin Decreased monoamine metabolites in frontotemporal dementia and Alzheimer's disease Neurobiology of Aging 19 5 1998 379 384
44. M.J. Taylor, S. Carney, J. Geddes, and G. Goodwin Folate for depressive disorders Cochrane Database of Systematic Reviews 2 2003 CD003390
45. A.J. Thomas, and J.T. O'Brien Depression and cognition in older adults Current Opinion in Psychiatry 21 1 2008 8 13
46. A.J. Thomas, I.N. Ferrier, R.N. Kalaria, R.H. Perry, A. Brown, and J.T. O'Brien A neuropathological study of vascular factors in late-life depression Journal of Neurology, Neurosurgery, and Psychiatry 70 1 2001 83 87
47. F.W. Unverzagt, L.A. McClure, V.G. Wadley, N.S. Jenny, R.C. Go, and M. Cushman Vascular risk factors and cognitive impairment in a stroke-free cohort Neurology 77 19 2011 1729 1736
48. A.K. Walker, D.P. Budac, S. Bisulco, A.W. Lee, R.A. Smith, and B. Beenders NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J MICE Neuropsychopharmacology 38 9 2013 1609 1616 10.1038/npp.2013.71
49. S.L. Weisenbach, L.A. Boore, and H.C. Kales Depression and cognitive impairment in older adults Current Psychiatry Reports 14 4 2012 280 288
50. K.A. Welsh, N. Butters, R.C. Mohs, D. Beekly, S. Edland, and G. Fillenbaum The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery Neurology 44 4 1994 609 614