TGF-β-induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops

Science Signaling

Volumn 7, Issue 345, 2014, Pages ra91-

  Zhang, Jingyu ^a,b   Tian, Xiao Jun ^b   Zhang, Hang ^b   Teng, Yue ^c   Li, Ruoyan ^a   Bai, Fan ^a   Elankumaran, Subbiah ^d   Xing, Jianhua ^b,e  

^a PEKING UNIVERSITY   (China)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^d VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^e BEIJING COMPUTATIONAL SCIENCE RESEARCH CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 200; MICRORNA 34; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL1; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; MESSENGER RNA; MIRN200 MICRORNA, HUMAN; MIRN34 MICRORNA, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; ZEB1 PROTEIN, HUMAN;

ARTICLE; BREAST EPITHELIUM; CELL ACTIVATION; CELL LEVEL; EPITHELIAL MESENCHYMAL TRANSITION; FEEDBACK SYSTEM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PHENOTYPE; PREDICTION; STEADY STATE; BIOLOGICAL MODEL; CELL LINE; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; NONPARAMETRIC TEST; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; EPITHELIAL-MESENCHYMAL TRANSITION; FEEDBACK, PHYSIOLOGICAL; FLOW CYTOMETRY; HOMEODOMAIN PROTEINS; HUMANS; MICRORNAS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84907877191     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005304     Document Type: Article

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