Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells

Toxicology Letters

Volumn 230, Issue 2, 2014, Pages 177-187

  Chantong, Boonrat ^a   Kratschmar, Denise V ^a   Lister, Adam ^a   Odermatt, Alex ^a  

^a Swiss Centre for Applied Human Toxicology   (Switzerland)

Author keywords

Dibutyltin; Inflammation; Microglia; Neurotoxicity; Organotin; Oxidative stress

Indexed keywords

DIBUTYLTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CALCIUM; CYBB PROTEIN, MOUSE; DI-N-BUTYLTIN; MEMBRANE PROTEIN; ORGANOTIN COMPOUND; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MICROGLIA; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; TOXICITY;

ANIMALS; CALCIUM; CELLS, CULTURED; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MEMBRANE GLYCOPROTEINS; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NADPH OXIDASE; NF-KAPPA B; ORGANOTIN COMPOUNDS; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES;

EID: 84907174933     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.03.001     Document Type: Article

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