Tributyltin-induced endoplasmic reticulum stress and its Ca2+-mediated mechanism

Toxicology and Applied Pharmacology

Volumn 272, Issue 1, 2013, Pages 137-146

  Isomura, Midori ^a   Kotake, Yaichiro ^a   Masuda, Kyoichi ^a   Miyara, Masatsugu ^a   Okuda, Katsuhiro ^a   Samizo, Shigeyoshi ^a   Sanoh, Seigo ^a   Hosoi, Toru ^a   Ozawa, Koichiro ^a   Ohta, Shigeru ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Calcium; Endoplasmic reticulum stress; Organotin

Indexed keywords

CALCIUM; COMPLEMENTARY DNA; DANTROLENE; DIBUTYLTIN; FURA 2 ACETOXYMETHYL ESTER; GLUCOSE REGULATED PROTEIN 78; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; MEMBRANE PROTEIN; MESSENGER RNA; ORGANOTIN COMPOUND; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THAPSIGARGIN; TRIBUTYLTIN; TRIBUTYLTIN CHLORIDE; TUNICAMYCIN; X BOX BINDING PROTEIN 1; XESTOSPONGIN C;

ARTICLE; CALCIUM DEPLETION; CELL CULTURE; CELL DEATH; CELL VIABILITY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROBLASTOMA CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RNA SPLICING;

2-(4-IODOPHENYL)-3-(4-NITROPHENYL)-5-(2,4-DISULFOPHENYL)-2H-TETRAZOLIUM; 4′,6-DIAMIDINO-2-PHENYLINDOLE DIHYDROCHLORIDE; BIS(TRI-N-BUTYLTIN) OXIDE; BOVINE SERUM ALBUMIN; BSA; C/EBP HOMOLOGOUS PROTEIN; CALCIUM; CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE; CCCP; CHOP; DAPI; DBT; DIBUTYLTIN; DMEM; DULBECCO'S MODIFIED EAGLE'S MEDIUM; EDTA; EIF2; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ER; ER-ASSOCIATED DEGRADATION; ERAD; ETHYLENEDIAMINETETRAACETIC ACID; EUKARYOTIC INITIATION FACTOR 2; FURA-2 ACETOXYMETHYLESTER; FURA-2 AM; GAPDH; GLUCOSE-REGULATED PROTEIN 78KDA; GLUCOSE-REGULATED PROTEIN 94KDA; GLYCELALDEHYDE-3-PHOSPHATE DEHYDROGENASE; GRP78; GRP94; HBSS; HEPES-BUFFERED SALT SOLUTION; INOSITOL 1,4,5-TRIPHOSPHATE; IP(3); MBT; MONOBUTYLTIN; ORGANOTIN; PBS; PBST; PHOSPHATE-BUFFERED SALINE; PHOSPHATE-BUFFERED SALINE CONTAINING TWEEN 20; REACTIVE OXYGEN SPECIES; ROS; SARCO/ENDOPLASMIC RETICULUM CA(2+)-ATPASE; SERCA; TBT; TBTO; TRIBUTYLTIN; UNFOLDED PROTEIN RESPONSE; UPR; VDCC; VOLTAGE-DEPENDENT CA(2+) CHANNEL; WST-1; X-BOX BINDING PROTEIN 1; XBP1;

BLOTTING, WESTERN; CALCIUM; CALCIUM SIGNALING; CELL LINE, TUMOR; CELL SURVIVAL; DANTROLENE; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; MICROARRAY ANALYSIS; MUSCLE RELAXANTS, CENTRAL; POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRIALKYLTIN COMPOUNDS;

EID: 84882770181     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.05.026     Document Type: Article

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