메뉴 건너뛰기




Volumn 53, Issue 9, 2012, Pages 5354-5361

Moderately reduced ATP levels promote oxidative stress and debilitate autophagic and phagocytic capacities in human RPE cells

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENOSINE TRIPHOSPHATE; GLUTATHIONE; MALONALDEHYDE; ATRACTYLOSIDE; ENZYME INHIBITOR; TERT BUTYL HYDROPEROXIDE;

EID: 84867884105     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-9845     Document Type: Article
Times cited : (72)

References (44)
  • 1
    • 46349093995 scopus 로고    scopus 로고
    • Brain mitochondrial dysfunction in aging
    • Boveris A, Navarro A. Brain mitochondrial dysfunction in aging. IUBMB Life. 2008;60:308-314.
    • (2008) IUBMB Life. , vol.60 , pp. 308-314
    • Boveris, A.1    Navarro, A.2
  • 2
    • 75349112375 scopus 로고    scopus 로고
    • Mitochondrial turnover and aging of long-lived postmitotic cells: The mitochondrial-lysosomal axis theory of aging
    • Terman A, Kurz T, Navratil M, Arriaga EA, Brunk UT. Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging. Antioxid Redox Signal. 2010;12:503-535.
    • (2010) Antioxid Redox Signal. , vol.12 , pp. 503-535
    • Terman, A.1    Kurz, T.2    Navratil, M.3    Arriaga, E.A.4    Brunk, U.T.5
  • 3
    • 77956571785 scopus 로고    scopus 로고
    • The importance of mitochondria in age-related and inherited eye disorders
    • Jarrett SG, Lewin AS, Boulton ME. The importance of mitochondria in age-related and inherited eye disorders. Ophthalmic Res. 2010;44:179-190.
    • (2010) Ophthalmic Res. , vol.44 , pp. 179-190
    • Jarrett, S.G.1    Lewin, A.S.2    Boulton, M.E.3
  • 5
    • 55649114157 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and its potential role in retinal degeneration
    • Jarrett SG, Lin H, Godley BF, Boulton ME. Mitochondrial DNA damage and its potential role in retinal degeneration. Prog Retin Eye Res. 2008;27:596-607.
    • (2008) Prog Retin Eye Res. , vol.27 , pp. 596-607
    • Jarrett, S.G.1    Lin, H.2    Godley, B.F.3    Boulton, M.E.4
  • 6
    • 81255151066 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in retinal diseases
    • Barot M, Gokulgandhi MR, Mitra AK. Mitochondrial dysfunction in retinal diseases. Curr Eye Res. 2011;36:1069-1077.
    • (2011) Curr Eye Res. , vol.36 , pp. 1069-1077
    • Barot, M.1    Gokulgandhi, M.R.2    Mitra, A.K.3
  • 7
    • 21244451958 scopus 로고    scopus 로고
    • The retinal pigment epithelium in visual function
    • Strauss O. The retinal pigment epithelium in visual function. Physiol Rev. 2005;85:845-881.
    • (2005) Physiol Rev. , vol.85 , pp. 845-881
    • Strauss, O.1
  • 8
    • 79959593126 scopus 로고    scopus 로고
    • Mitochondrial decay and impairment of antioxidant defenses in aging RPE cells
    • He Y, Tombran-Tink J. Mitochondrial decay and impairment of antioxidant defenses in aging RPE cells. Adv Exp Med Biol. 2010;664:165-183.
    • (2010) Adv Exp Med Biol. , vol.664 , pp. 165-183
    • He, Y.1    Tombran-Tink, J.2
  • 9
    • 33847059997 scopus 로고    scopus 로고
    • The mitochondrial energy transduction system and the aging process
    • Navarro A, Boveris A. The mitochondrial energy transduction system and the aging process. Am J Physiol Cell Physiol. 2007; 292:C670-C686.
    • (2007) Am J Physiol Cell Physiol. , vol.292
    • Navarro, A.1    Boveris, A.2
  • 11
    • 10044255422 scopus 로고    scopus 로고
    • Lipids and lipid peroxidation products in the pathogenesis of age-related macular degeneration
    • Kopitz J, Holz FG, Kaemmerer E, Schutt F. Lipids and lipid peroxidation products in the pathogenesis of age-related macular degeneration. Biochimie. 2004;86:825-831.
    • (2004) Biochimie. , vol.86 , pp. 825-831
    • Kopitz, J.1    Holz, F.G.2    Kaemmerer, E.3    Schutt, F.4
  • 12
    • 77649168211 scopus 로고    scopus 로고
    • Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action
    • Krohne TU, Kaemmerer E, Holz FG, Kopitz J. Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action. Exp Eye Res. 2010;90:261-266.
    • (2010) Exp Eye Res. , vol.90 , pp. 261-266
    • Krohne, T.U.1    Kaemmerer, E.2    Holz, F.G.3    Kopitz, J.4
  • 13
    • 77649188326 scopus 로고    scopus 로고
    • Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells
    • Krohne TU, Stratmann NK, Kopitz J, Holz FG. Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells. Exp Eye Res. 2010;90: 465-471.
    • (2010) Exp Eye Res. , vol.90 , pp. 465-471
    • Krohne, T.U.1    Stratmann, N.K.2    Kopitz, J.3    Holz, F.G.4
  • 14
    • 20444418659 scopus 로고    scopus 로고
    • Blue light induces mitochondrial DNA damage and free radical production in epithelial cells
    • Godley BF, Shamsi FA, Liang FQ, Jarrett SG, Davies S, Boulton M. Blue light induces mitochondrial DNA damage and free radical production in epithelial cells. J Biol Chem. 2005;280: 21061-21066.
    • (2005) J Biol Chem. , vol.280 , pp. 21061-21066
    • Godley, B.F.1    Shamsi, F.A.2    Liang, F.Q.3    Jarrett, S.G.4    Davies, S.5    Boulton, M.6
  • 15
    • 54049085790 scopus 로고    scopus 로고
    • The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells
    • Vives-Bauza C, Anand M, Shirazi AK, et al. The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells. J Biol Chem. 2008; 283:24770-24780.
    • (2008) J Biol Chem. , vol.283 , pp. 24770-24780
    • Vives-Bauza, C.1    Anand, M.2    Shirazi, A.K.3
  • 16
    • 52049113898 scopus 로고    scopus 로고
    • The ADP and ATP transport in mitochondria and its carrier
    • Klingenberg M. The ADP and ATP transport in mitochondria and its carrier. Biochim Biophys Acta. 2008;1778:1978-2021.
    • (2008) Biochim Biophys Acta. , vol.1778 , pp. 1978-2021
    • Klingenberg, M.1
  • 17
    • 12744277558 scopus 로고    scopus 로고
    • Acrolein induces oxidative stress in brain mitochondria
    • Luo J, Shi R. Acrolein induces oxidative stress in brain mitochondria. Neurochem Int. 2005;46:243-252.
    • (2005) Neurochem Int. , vol.46 , pp. 243-252
    • Luo, J.1    Shi, R.2
  • 18
    • 0028903353 scopus 로고
    • A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture
    • Davis AA, Bernstein PS, Bok D, Turner J, Nachtigal M, Hunt RC. A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture. Invest Ophthalmol Vis Sci. 1995;36:955-964.
    • (1995) Invest Ophthalmol Vis Sci. , vol.36 , pp. 955-964
    • Davis, A.A.1    Bernstein, P.S.2    Bok, D.3    Turner, J.4    Nachtigal, M.5    Hunt, R.C.6
  • 20
    • 0033017053 scopus 로고    scopus 로고
    • Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin
    • Holz FG, Schutt F, Kopitz J, et al. Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin. Invest Ophthalmol Vis Sci. 1999;40:737-743.
    • (1999) Invest Ophthalmol Vis Sci. , vol.40 , pp. 737-743
    • Holz, F.G.1    Schutt, F.2    Kopitz, J.3
  • 21
    • 0022896893 scopus 로고
    • Use of electrical methods in the study of hepatocytic autophagy
    • Gordon PB, Seglen PO. Use of electrical methods in the study of hepatocytic autophagy. Biomed Biochim Acta. 1986;45: 1635-1645.
    • (1986) Biomed Biochim Acta. , vol.45 , pp. 1635-1645
    • Gordon, P.B.1    Seglen, P.O.2
  • 22
  • 23
    • 2442648066 scopus 로고    scopus 로고
    • Inhibition of the ATPdriven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of agerelated macular degeneration
    • Bergmann M, Schutt F, Holz FG, Kopitz J. Inhibition of the ATPdriven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of agerelated macular degeneration. FASEB J. 2004;18:562-564.
    • (2004) FASEB J. , vol.18 , pp. 562-564
    • Bergmann, M.1    Schutt, F.2    Holz, F.G.3    Kopitz, J.4
  • 25
    • 33746406453 scopus 로고    scopus 로고
    • Mitochondrial alterations of retinal pigment epithelium in agerelated macular degeneration
    • Feher J, Kovacs I, Artico M, Cavallotti C, Papale A, Balacco GC. Mitochondrial alterations of retinal pigment epithelium in agerelated macular degeneration. Neurobiol Aging. 2006;27:983-993.
    • (2006) Neurobiol Aging. , vol.27 , pp. 983-993
    • Feher, J.1    Kovacs, I.2    Artico, M.3    Cavallotti, C.4    Papale, A.5    Balacco, G.C.6
  • 26
  • 27
    • 0025122326 scopus 로고
    • Glucose uptake, hexose monophosphate shunt activity, and oxygen consumption in cultured human retinal pigment epithelial cells
    • Miceli MV, Newsome DA, Schriver GW. Glucose uptake, hexose monophosphate shunt activity, and oxygen consumption in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1990;31:277-283.
    • (1990) Invest Ophthalmol Vis Sci. , vol.31 , pp. 277-283
    • Miceli, M.V.1    Newsome, D.A.2    Schriver, G.W.3
  • 28
    • 0011228990 scopus 로고
    • Metabolism of the retina. I. Respiration of cattle retina
    • Futterman S, Kinoshita JH. Metabolism of the retina. I. Respiration of cattle retina. J Biol Chem. 1959;234:723-726.
    • (1959) J Biol Chem. , vol.234 , pp. 723-726
    • Futterman, S.1    Kinoshita, J.H.2
  • 29
    • 23944478990 scopus 로고    scopus 로고
    • A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress
    • Del Rio D, Stewart AJ, Pellegrini N. A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress. Nutr Metab Cardiovasc Dis. 2005;15:316-328.
    • (2005) Nutr Metab Cardiovasc Dis. , vol.15 , pp. 316-328
    • Del Rio, D.1    Stewart, A.J.2    Pellegrini, N.3
  • 30
    • 0041342065 scopus 로고    scopus 로고
    • Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium
    • Schutt F, Bergmann M, Holz FG, Kopitz J. Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2003;44:3663-3668.
    • (2003) Invest Ophthalmol Vis Sci. , vol.44 , pp. 3663-3668
    • Schutt, F.1    Bergmann, M.2    Holz, F.G.3    Kopitz, J.4
  • 31
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med. 1991;11:81-128.
    • (1991) Free Radic Biol Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 33
    • 84863986254 scopus 로고    scopus 로고
    • The innate immune response to products of phospholipid peroxidation
    • [published online ahead of print January 28, 2012]
    • Weismann D, Binder CJ. The innate immune response to products of phospholipid peroxidation [published online ahead of print January 28, 2012]. Biochim Biophys Acta.
    • Biochim Biophys Acta
    • Weismann, D.1    Binder, C.J.2
  • 34
    • 37549048032 scopus 로고    scopus 로고
    • Review of genetics in age related macular degeneration
    • Montezuma SR, Sobrin L, Seddon JM. Review of genetics in age related macular degeneration. Semin Ophthalmol. 2007;22: 229-240.
    • (2007) Semin Ophthalmol. , vol.22 , pp. 229-240
    • Montezuma, S.R.1    Sobrin, L.2    Seddon, J.M.3
  • 35
    • 84856918255 scopus 로고    scopus 로고
    • Genetics of immunological and inflammatory components in age-related macular degeneration
    • Tuo J, Grob S, Zhang K, Chan CC. Genetics of immunological and inflammatory components in age-related macular degeneration. Ocul Immunol Inflamm. 2012;20:27-36.
    • (2012) Ocul Immunol Inflamm. , vol.20 , pp. 27-36
    • Tuo, J.1    Grob, S.2    Zhang, K.3    Chan, C.C.4
  • 37
    • 70349112712 scopus 로고    scopus 로고
    • Nuclear DNA damage as a direct cause of aging
    • Best BP. Nuclear DNA damage as a direct cause of aging. Rejuvenation Res. 2009;12:199-208.
    • (2009) Rejuvenation Res. , vol.12 , pp. 199-208
    • Best, B.P.1
  • 39
    • 0026720018 scopus 로고
    • Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes
    • Mithofer K, Sandy MS, Smith MT, Di Monte D. Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes. Arch Biochem Biophys. 1992;295:132-136.
    • (1992) Arch Biochem Biophys. , vol.295 , pp. 132-136
    • Mithofer, K.1    Sandy, M.S.2    Smith, M.T.3    Di Monte, D.4
  • 41
    • 66049133683 scopus 로고    scopus 로고
    • Aging: Central role for autophagy and the lysosomal degradative system
    • Rajawat YS, Hilioti Z, Bossis I. Aging: central role for autophagy and the lysosomal degradative system. Ageing Res Rev. 2009;8:199-213.
    • (2009) Ageing Res Rev. , vol.8 , pp. 199-213
    • Rajawat, Y.S.1    Hilioti, Z.2    Bossis, I.3
  • 43
    • 77956569706 scopus 로고    scopus 로고
    • Chemistry and biochemistry of lipid peroxidation products
    • Gueraud F, Atalay M, Bresgen N, et al. Chemistry and biochemistry of lipid peroxidation products. Free Radic Res. 2010;44:1098-1124.
    • (2010) Free Radic Res. , vol.44 , pp. 1098-1124
    • Gueraud, F.1    Atalay, M.2    Bresgen, N.3
  • 44
    • 0024545981 scopus 로고
    • Energy dependence of different steps in the autophagic-lysosomal pathway
    • Plomp PJ, Gordon PB, Meijer AJ, Hoyvik H, Seglen PO. Energy dependence of different steps in the autophagic-lysosomal pathway. J Biol Chem. 1989;264:6699-6704.
    • (1989) J Biol Chem. , vol.264 , pp. 6699-6704
    • Plomp, P.J.1    Gordon, P.B.2    Meijer, A.J.3    Hoyvik, H.4    Seglen, P.O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.