Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular infammation

Journal of Clinical Investigation

Volumn 123, Issue 2, 2013, Pages 887-902

  Gandhirajan, Rajesh Kumar ^a,b   Meng, Shu ^a   Chandramoorthy, Harish C ^a,b   Mallilankaraman, Karthik ^a,b   Mancarella, Salvatore ^a   Gao, Hui ^a   Razmpour, Roshanak ^a   Yang, Xiao Feng ^a   Houser, Steven R ^a   Chen, Ju ^c   Koch, Walter J ^a,b   Wang, Hong ^a   Soboloff, Jonathan ^a   Gill, Donald L ^a   Madesh, Muniswamy ^a,b  

^a TEMPLE UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BTP 2; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; GRANULOCYTE COLONY STIMULATING FACTOR; INOSITOL TRISPHOSPHATE; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; STROMAL INTERACTION MOLECULE 1; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CALCIUM SIGNALING; CELL DEATH; CELL MIGRATION; CHELATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME INHIBITION; FEMALE; LUNG BLOOD VESSEL; LUNG EDEMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; SEPSIS; SIGNAL TRANSDUCTION; VASCULITIS;

ACUTE LUNG INJURY; ANILIDES; ANIMALS; CALCIUM SIGNALING; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FEMALE; GENE KNOCKDOWN TECHNIQUES; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; LIPOPOLYSACCHARIDES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NADPH OXIDASE; NFATC TRANSCRIPTION FACTORS; REACTIVE OXYGEN SPECIES; SEPSIS; SIGNAL TRANSDUCTION; THIADIAZOLES;

EID: 84873326523     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI65647     Document Type: Article

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