메뉴 건너뛰기




Volumn 5, Issue 8, 2014, Pages

The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; MEMBRANE PROTEIN; PKR LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN IRE1 ALPHA; PROTEIN KINASE; TAU PROTEIN; TAUROURSODEOXYCHOLIC ACID; TUNICAMYCIN; UNCLASSIFIED DRUG; DEOXYGLUCOSE; EIF2AK3 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; TAUROCHENODEOXYCHOLIC ACID;

EID: 84906852572     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.354     Document Type: Article
Times cited : (72)

References (47)
  • 1
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • Ballatore C, Lee VM, Trojanowski JQ. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat Rev Neurosci 2007; 8: 663-672.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 2
    • 39749165656 scopus 로고    scopus 로고
    • Differential regulation of dynein and kinesin motor proteins by tau
    • Dixit R, Ross JL, Goldman YE, Holzbaur EL. Differential regulation of dynein and kinesin motor proteins by tau. Science 2008; 319: 1086-1089.
    • (2008) Science , vol.319 , pp. 1086-1089
    • Dixit, R.1    Ross, J.L.2    Goldman, Y.E.3    Holzbaur, E.L.4
  • 4
    • 70349322563 scopus 로고    scopus 로고
    • Mammalian hibernation: Differential gene expression and novel application of epigenetic controls
    • Morin P Jr., Storey KB. Mammalian hibernation: differential gene expression and novel application of epigenetic controls. Int J Dev Biol 2009; 53: 433-442.
    • (2009) Int J Dev Biol , vol.53 , pp. 433-442
    • Morin Jr., P.1    Storey, K.B.2
  • 5
    • 79251563831 scopus 로고    scopus 로고
    • The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation
    • Stieler JT, Bullmann T, Kohl F, Toien O, Bruckner MK, Hartig W et al. The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation. PLoS One 2011; 6: e14530.
    • (2011) PLoS One , vol.6
    • Stieler, J.T.1    Bullmann, T.2    Kohl, F.3    Toien, O.4    Bruckner, M.K.5    Hartig, W.6
  • 7
    • 0032716550 scopus 로고    scopus 로고
    • Starvation induces tau hyperphosphorylation in mouse brain: Implications for Alzheimer's disease
    • Yanagisawa M, Planel E, Ishiguro K, Fujita SC. Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease. FEBS Lett 1999; 461: 329-333.
    • (1999) FEBS Lett , vol.461 , pp. 329-333
    • Yanagisawa, M.1    Planel, E.2    Ishiguro, K.3    Fujita, S.C.4
  • 8
    • 71949112504 scopus 로고    scopus 로고
    • Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes
    • Kim B, Backus C, Oh S, Hayes JM, Feldman EL. Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes. Endocrinology 2009; 150: 5294-5301.
    • (2009) Endocrinology , vol.150 , pp. 5294-5301
    • Kim, B.1    Backus, C.2    Oh, S.3    Hayes, J.M.4    Feldman, E.L.5
  • 9
    • 37249040432 scopus 로고    scopus 로고
    • Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms
    • Planel E, Tatebayashi Y, Miyasaka T, Liu L, Wang L, Herman M et al. Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms. J Neurosci 2007; 27: 13635-13648.
    • (2007) J Neurosci , vol.27 , pp. 13635-13648
    • Planel, E.1    Tatebayashi, Y.2    Miyasaka, T.3    Liu, L.4    Wang, L.5    Herman, M.6
  • 10
    • 70949084806 scopus 로고    scopus 로고
    • Experimental diabetes mellitus exacerbates tau pathology in a transgenicmouse model of Alzheimer's disease
    • Ke YD, Delerue F, Gladbach A, Gotz J, Ittner LM. Experimental diabetes mellitus exacerbates tau pathology in a transgenicmouse model of Alzheimer's disease. PLoS One 2009; 4: e7917.
    • (2009) PLoS One , vol.4
    • Ke, Y.D.1    Delerue, F.2    Gladbach, A.3    Gotz, J.4    Ittner, L.M.5
  • 12
    • 78650122129 scopus 로고    scopus 로고
    • Metabolic-cognitive syndrome: A cross-talk between metabolic syndrome and Alzheimer's disease
    • Frisardi V, Solfrizzi V, Seripa D, Capurso C, Santamato A, Sancarlo D et al. Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease. Ageing Res Rev 2010; 9: 399-417.
    • (2010) Ageing Res Rev , vol.9 , pp. 399-417
    • Frisardi, V.1    Solfrizzi, V.2    Seripa, D.3    Capurso, C.4    Santamato, A.5    Sancarlo, D.6
  • 16
    • 84858000638 scopus 로고    scopus 로고
    • The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies
    • Nijholt DA, van Haastert ES, Rozemuller AJ, Scheper W, Hoozemans JJ. The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies. J Pathol 2012; 226: 693-702.
    • (2012) J Pathol , vol.226 , pp. 693-702
    • Nijholt, D.A.1    Van Haastert, E.S.2    Rozemuller, A.J.3    Scheper, W.4    Hoozemans, J.J.5
  • 17
    • 82255173966 scopus 로고    scopus 로고
    • The unfolded protein response: From stress pathway to homeostatic regulation
    • Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011; 334: 1081-1086.
    • (2011) Science , vol.334 , pp. 1081-1086
    • Walter, P.1    Ron, D.2
  • 18
    • 84861473427 scopus 로고    scopus 로고
    • Endoplasmic reticulum: The unfolded protein response is tangled in neurodegeneration
    • Hoozemans JJ, Scheper W. Endoplasmic reticulum: the unfolded protein response is tangled in neurodegeneration. Int J Biochem Cell Biol 2012; 44: 1295-1298.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 1295-1298
    • Hoozemans, J.J.1    Scheper, W.2
  • 19
    • 33846203763 scopus 로고    scopus 로고
    • Hibernation model of tau phosphorylation in hamsters: Selective vulnerability of cholinergic basal forebrain neurons - Implications for Alzheimer's disease
    • Hartig W, Stieler J, Boerema AS, Wolf J, Schmidt U, Weissfuss J et al. Hibernation model of tau phosphorylation in hamsters: selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease. Eur J Neurosci 2007; 25: 69-80.
    • (2007) Eur J Neurosci , vol.25 , pp. 69-80
    • Hartig, W.1    Stieler, J.2    Boerema, A.S.3    Wolf, J.4    Schmidt, U.5    Weissfuss, J.6
  • 20
    • 78650469377 scopus 로고    scopus 로고
    • LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3beta in vivo and in vitro
    • Fu ZQ, Yang Y, Song J, Jiang Q, Lin ZC, Wang Q et al. LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3beta in vivo and in vitro. J Alzheimers Dis 2010; 21: 1107-1117.
    • (2010) J Alzheimers Dis , vol.21 , pp. 1107-1117
    • Fu, Z.Q.1    Yang, Y.2    Song, J.3    Jiang, Q.4    Lin, Z.C.5    Wang, Q.6
  • 21
    • 0037160134 scopus 로고    scopus 로고
    • Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation
    • Song L, De SP, Jope RS. Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. J Biol Chem 2002; 277: 44701-44708.
    • (2002) J Biol Chem , vol.277 , pp. 44701-44708
    • Song, L.1    De, S.P.2    Jope, R.S.3
  • 22
    • 12144289492 scopus 로고    scopus 로고
    • Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: Implications for Alzheimer's disease
    • Planel E, Miyasaka T, Launey T, Chui DH, Tanemura K, Sato S et al. Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease. J Neurosci 2004; 24: 2401-2411.
    • (2004) J Neurosci , vol.24 , pp. 2401-2411
    • Planel, E.1    Miyasaka, T.2    Launey, T.3    Chui, D.H.4    Tanemura, K.5    Sato, S.6
  • 23
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006; 313: 1137-1140.
    • (2006) Science , vol.313 , pp. 1137-1140
    • Ozcan, U.1    Yilmaz, E.2    Ozcan, L.3    Furuhashi, M.4    Vaillancourt, E.5    Smith, R.O.6
  • 24
    • 0036725164 scopus 로고    scopus 로고
    • Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation
    • Xie Q, Khaoustov VI, Chung CC, Sohn J, Krishnan B, Lewis DE et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology 2002; 36: 592-601.
    • (2002) Hepatology , vol.36 , pp. 592-601
    • Xie, Q.1    Khaoustov, V.I.2    Chung, C.C.3    Sohn, J.4    Krishnan, B.5    Lewis, D.E.6
  • 25
    • 84866905708 scopus 로고    scopus 로고
    • Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3- dihydro-1H-indol-5-yl)-7H-p yrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK)
    • Axten JM, Medina JR, Feng Y, Shu A, Romeril SP, Grant SW et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl) -7H-p yrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem 2012; 55: 7193-7207.
    • (2012) J Med Chem , vol.55 , pp. 7193-7207
    • Axten, J.M.1    Medina, J.R.2    Feng, Y.3    Shu, A.4    Romeril, S.P.5    Grant, S.W.6
  • 26
    • 79960809092 scopus 로고    scopus 로고
    • Neuronal activity regulates the regional vulnerability to amyloid-beta deposition
    • Bero AW, Yan P, Roh JH, Cirrito JR, Stewart FR, Raichle ME et al. Neuronal activity regulates the regional vulnerability to amyloid-beta deposition. Nat Neurosci 2011; 14: 750-756.
    • (2011) Nat Neurosci , vol.14 , pp. 750-756
    • Bero, A.W.1    Yan, P.2    Roh, J.H.3    Cirrito, J.R.4    Stewart, F.R.5    Raichle, M.E.6
  • 27
    • 0029013727 scopus 로고
    • Staging of Alzheimer's disease-related neurofibrillary changes
    • Braak H, Braak E. Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol Aging 1995; 16: 271-278.
    • (1995) Neurobiol Aging , vol.16 , pp. 271-278
    • Braak, H.1    Braak, E.2
  • 31
    • 62649129085 scopus 로고    scopus 로고
    • Decreased cortical glucose metabolism in converters from CDR 0.5 to Alzheimer's disease in a community: The Osaki-Tajiri Project
    • Ishii H, Ishikawa H, Meguro K, Tashiro M, Yamaguchi S. Decreased cortical glucose metabolism in converters from CDR 0.5 to Alzheimer's disease in a community: the Osaki-Tajiri Project. Int Psychogeriatr 2009; 21: 148-156.
    • (2009) Int Psychogeriatr , vol.21 , pp. 148-156
    • Ishii, H.1    Ishikawa, H.2    Meguro, K.3    Tashiro, M.4    Yamaguchi, S.5
  • 32
    • 0042736668 scopus 로고    scopus 로고
    • Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: A PET follow-up study
    • Drzezga A, Lautenschlager N, Siebner H, Riemenschneider M, Willoch F, Minoshima S et al. Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study. Eur J Nucl Med Mol Imaging 2003; 30: 1104-1113.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 1104-1113
    • Drzezga, A.1    Lautenschlager, N.2    Siebner, H.3    Riemenschneider, M.4    Willoch, F.5    Minoshima, S.6
  • 33
    • 84880208401 scopus 로고    scopus 로고
    • Comparing brain amyloid deposition, glucose metabolism, and atrophy in mild cognitive impairment with and without a family history of dementia
    • Mosconi L, Andrews RD, Matthews DC. Comparing brain amyloid deposition, glucose metabolism, and atrophy in mild cognitive impairment with and without a family history of dementia. J Alzheimers Dis 2013; 35: 509-524.
    • (2013) J Alzheimers Dis , vol.35 , pp. 509-524
    • Mosconi, L.1    Andrews, R.D.2    Matthews, D.C.3
  • 34
    • 0042837944 scopus 로고    scopus 로고
    • Limbic hypometabolism in Alzheimer's disease and mild cognitive impairment
    • Nestor PJ, Fryer TD, Smielewski P, Hodges JR. Limbic hypometabolism in Alzheimer's disease and mild cognitive impairment. Ann Neurol 2003; 54: 343-351.
    • (2003) Ann Neurol , vol.54 , pp. 343-351
    • Nestor, P.J.1    Fryer, T.D.2    Smielewski, P.3    Hodges, J.R.4
  • 35
    • 84878918038 scopus 로고    scopus 로고
    • Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions
    • Burns CM, Chen K, Kaszniak AW, Lee W, Alexander GE, Bandy D et al. Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions. Neurology 2013; 80: 1557-1564.
    • (2013) Neurology , vol.80 , pp. 1557-1564
    • Burns, C.M.1    Chen, K.2    Kaszniak, A.W.3    Lee, W.4    Alexander, G.E.5    Bandy, D.6
  • 36
    • 84876786043 scopus 로고    scopus 로고
    • GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease
    • Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM et al. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron 2013; 78: 256-268.
    • (2013) Neuron , vol.78 , pp. 256-268
    • Cruchaga, C.1    Kauwe, J.S.2    Harari, O.3    Jin, S.C.4    Cai, Y.5    Karch, C.M.6
  • 37
    • 84859718265 scopus 로고    scopus 로고
    • Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
    • Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A et al. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Invest 2012; 122: 1316-1338.
    • (2012) J Clin Invest , vol.122 , pp. 1316-1338
    • Talbot, K.1    Wang, H.Y.2    Kazi, H.3    Han, L.Y.4    Bakshi, K.P.5    Stucky, A.6
  • 38
    • 84878333056 scopus 로고    scopus 로고
    • Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
    • Abisambra JF, Jinwal UK, Blair LJ, O'Leary JC III, Li Q, Brady S et al. Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation. J Neurosci 2013; 33: 9498-9507.
    • (2013) J Neurosci , vol.33 , pp. 9498-9507
    • Abisambra, J.F.1    Jinwal, U.K.2    Blair, L.J.3    O'Leary III, J.C.4    Li, Q.5    Brady, S.6
  • 39
    • 84883332353 scopus 로고    scopus 로고
    • Tau pathology as a cause and consequence of the UPR
    • Stoveken BJ. Tau pathology as a cause and consequence of the UPR. J Neurosci 2013; 33: 14285-14287.
    • (2013) J Neurosci , vol.33 , pp. 14285-14287
    • Stoveken, B.J.1
  • 41
    • 84885454414 scopus 로고    scopus 로고
    • A new PERKspective on neurodegeneration
    • Scheper W, Hoozemans JJ. A new PERKspective on neurodegeneration. Sci Transl Med 2013; 5: 206fs37.
    • (2013) Sci Transl Med , vol.5
    • Scheper, W.1    Hoozemans, J.J.2
  • 42
    • 84883453343 scopus 로고    scopus 로고
    • Suppression of eIF2alpha kinases alleviates Alzheimer's disease-related plasticity and memory deficits
    • Ma T, Trinh MA, Wexler AJ, Bourbon C, Gatti E, Pierre P et al. Suppression of eIF2alpha kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci 2013; 16: 1299-1305.
    • (2013) Nat Neurosci , vol.16 , pp. 1299-1305
    • Ma, T.1    Trinh, M.A.2    Wexler, A.J.3    Bourbon, C.4    Gatti, E.5    Pierre, P.6
  • 43
    • 84885463900 scopus 로고    scopus 로고
    • Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice
    • Moreno JA, Halliday M, Molloy C, Radford H, Verity N, Axten JM et al. Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice. Sci Transl Med 2013; 5: 206ra138.
    • (2013) Sci Transl Med , vol.5
    • Moreno, J.A.1    Halliday, M.2    Molloy, C.3    Radford, H.4    Verity, N.5    Axten, J.M.6
  • 44
    • 84861450392 scopus 로고    scopus 로고
    • Sustained translational repression by eIF2alpha-P mediates prion neurodegeneration
    • Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG et al. Sustained translational repression by eIF2alpha-P mediates prion neurodegeneration. Nature 2012; 485: 507-511.
    • (2012) Nature , vol.485 , pp. 507-511
    • Moreno, J.A.1    Radford, H.2    Peretti, D.3    Steinert, J.R.4    Verity, N.5    Martin, M.G.6
  • 45
    • 79959689333 scopus 로고    scopus 로고
    • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
    • Hoglinger GU, Melhem NM, Dickson DW, Sleiman PM, Wang LS, Klei L et al. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nat Genet 2011; 43: 699-705.
    • (2011) Nat Genet , vol.43 , pp. 699-705
    • Hoglinger, G.U.1    Melhem, N.M.2    Dickson, D.W.3    Sleiman, P.M.4    Wang, L.S.5    Klei, L.6
  • 47
    • 0031775655 scopus 로고    scopus 로고
    • Rapid synthesis of biotin-, digoxigenin-, trinitrophenyl-, and fluorochrome-labeled tyramides and their application for in situ hybridization using CARD amplification
    • Hopman AH, Ramaekers FC, Speel EJ. Rapid synthesis of biotin-, digoxigenin-, trinitrophenyl-, and fluorochrome-labeled tyramides and their application for In situ hybridization using CARD amplification. J Histochem Cytochem 1998; 46: 771-777.
    • (1998) J Histochem Cytochem , vol.46 , pp. 771-777
    • Hopman, A.H.1    Ramaekers, F.C.2    Speel, E.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.