The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies

Journal of Pathology

Volumn 226, Issue 5, 2012, Pages 693-702

  Nijholt, Diana A T ^a   Van Haastert, Elise S ^b   Rozemuller, Annemieke J M ^b   Scheper, Wiep ^a   Hoozemans, Jeroen J M ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Endoplasmic reticulum stress; Frontotemporal lobar degeneration; Tau; Unfolded protein response

Indexed keywords

PANCREATIC ENDOPLASMIC RETICULUM KINASE; PHOSPHOTRANSFERASE; PROTEIN IRE1; TAU PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRAIN NERVE CELL; CHROMOSOME 17; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; GLIA; HETEROZYGOTE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NEUROPATHOLOGY; PARKINSONISM; PICK PRESENILE DEMENTIA; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN PHOSPHORYLATION; UNFOLDED PROTEIN RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; AUTOPSY; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; EIF-2 KINASE; ENDORIBONUCLEASES; FEMALE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TAU PROTEINS; TAUOPATHIES; UNFOLDED PROTEIN RESPONSE; UP-REGULATION;

EID: 84858000638     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.3969     Document Type: Article

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