-
1
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments
-
Alonso A., Zaidi T., Novak M., Grundke-Iqbal I., Iqbal K. Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. Proc. Natl. Acad. Sci. U. S. A 2001, 98:6923-6928.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A
, vol.98
, pp. 6923-6928
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
2
-
-
77957256216
-
Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration
-
Alonso A.D., Di C.J., Li B., Corbo C.P., Alaniz M.E., Grundke-Iqbal I., Iqbal K. Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration. J. Biol. Chem. 2010, 285:30851-30860.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 30851-30860
-
-
Alonso, A.D.1
Di, C.J.2
Li, B.3
Corbo, C.P.4
Alaniz, M.E.5
Grundke-Iqbal, I.6
Iqbal, K.7
-
3
-
-
84860468095
-
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
-
Appenzeller-Herzog C., Hall M.N. Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends Cell Biol. 2012, 22:274-282.
-
(2012)
Trends Cell Biol.
, vol.22
, pp. 274-282
-
-
Appenzeller-Herzog, C.1
Hall, M.N.2
-
4
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
-
Ballatore C., Lee V.M., Trojanowski J.Q. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 2007, 8:663-672.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.2
Trojanowski, J.Q.3
-
5
-
-
0024587074
-
Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease
-
Bancher C., Brunner C., Lassmann H., Budka H., Jellinger K., Wiche G., Seitelberger F., Grundke-Iqbal I., Iqbal K., Wisniewski H.M. Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res. 1989, 477:90-99.
-
(1989)
Brain Res.
, vol.477
, pp. 90-99
-
-
Bancher, C.1
Brunner, C.2
Lassmann, H.3
Budka, H.4
Jellinger, K.5
Wiche, G.6
Seitelberger, F.7
Grundke-Iqbal, I.8
Iqbal, K.9
Wisniewski, H.M.10
-
6
-
-
0035665719
-
The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation
-
Bax B., Carter P.S., Lewis C., Guy A.R., Bridges A., Tanner R., Pettman G., Mannix C., Culbert A.A., Brown M.J., Smith D.G., Reith A.D. The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation. Structure 2001, 9:1143-1152.
-
(2001)
Structure
, vol.9
, pp. 1143-1152
-
-
Bax, B.1
Carter, P.S.2
Lewis, C.3
Guy, A.R.4
Bridges, A.5
Tanner, R.6
Pettman, G.7
Mannix, C.8
Culbert, A.A.9
Brown, M.J.10
Smith, D.G.11
Reith, A.D.12
-
7
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
-
Boland B., Kumar A., Lee S., Platt F.M., Wegiel J., Yu W.H., Nixon R.A. Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci. 2008, 28:6926-6937.
-
(2008)
J. Neurosci.
, vol.28
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
8
-
-
0011913143
-
Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells
-
Bowman E.J., Siebers A., Altendorf K. Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Proc. Natl. Acad. Sci. U. S. A 1988, 85:7972-7976.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A
, vol.85
, pp. 7972-7976
-
-
Bowman, E.J.1
Siebers, A.2
Altendorf, K.3
-
9
-
-
0030830304
-
Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3beta transgenes
-
Brownlees J., Irving N.G., Brion J.P., Gibb B.J., Wagner U., Woodgett J., Miller C.C. Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3beta transgenes. Neuroreport 1997, 8:3251-3255.
-
(1997)
Neuroreport
, vol.8
, pp. 3251-3255
-
-
Brownlees, J.1
Irving, N.G.2
Brion, J.P.3
Gibb, B.J.4
Wagner, U.5
Woodgett, J.6
Miller, C.C.7
-
10
-
-
35848951621
-
Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner
-
Chafekar S.M., Hoozemans J.J., Zwart R., Baas F., Scheper W. Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner. Antioxid. Redox. Signal 2007, 9:2245-2254.
-
(2007)
Antioxid. Redox. Signal
, vol.9
, pp. 2245-2254
-
-
Chafekar, S.M.1
Hoozemans, J.J.2
Zwart, R.3
Baas, F.4
Scheper, W.5
-
11
-
-
53649085618
-
Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity
-
Chafekar S.M., Zwart R., Veerhuis R., Vanderstichele H., Baas F., Scheper W. Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity. Curr. Alzheimer Res. 2008, 5:469-474.
-
(2008)
Curr. Alzheimer Res.
, vol.5
, pp. 469-474
-
-
Chafekar, S.M.1
Zwart, R.2
Veerhuis, R.3
Vanderstichele, H.4
Baas, F.5
Scheper, W.6
-
12
-
-
0033587742
-
Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons
-
Chalecka-Franaszek E., Chuang D.M. Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons. Proc. Natl. Acad. Sci. U. S. A 1999, 96:8745-8750.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A
, vol.96
, pp. 8745-8750
-
-
Chalecka-Franaszek, E.1
Chuang, D.M.2
-
13
-
-
0037414833
-
Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding
-
Cho J.H., Johnson G.V. Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding. J. Biol. Chem. 2003, 278:187-193.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 187-193
-
-
Cho, J.H.1
Johnson, G.V.2
-
14
-
-
78149411188
-
Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo
-
Cowan C.M., Bossing T., Page A., Shepherd D., Mudher A. Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo. Acta Neuropathol. 2010, 120:593-604.
-
(2010)
Acta Neuropathol.
, vol.120
, pp. 593-604
-
-
Cowan, C.M.1
Bossing, T.2
Page, A.3
Shepherd, D.4
Mudher, A.5
-
15
-
-
51349143580
-
Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin
-
Cuchillo-Ibanez I., Seereeram A., Byers H.L., Leung K.Y., Ward M.A., Anderton B.H., Hanger D.P. Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin. FASEB J. 2008, 22:3186-3195.
-
(2008)
FASEB J.
, vol.22
, pp. 3186-3195
-
-
Cuchillo-Ibanez, I.1
Seereeram, A.2
Byers, H.L.3
Leung, K.Y.4
Ward, M.A.5
Anderton, B.H.6
Hanger, D.P.7
-
16
-
-
58149393972
-
Matrix-dependent local retention of secretory vesicle cargo in cortical neurons
-
De Wit J., Toonen R.F., Verhage M. Matrix-dependent local retention of secretory vesicle cargo in cortical neurons. J. Neurosci. 2009, 29:23-37.
-
(2009)
J. Neurosci.
, vol.29
, pp. 23-37
-
-
De Wit, J.1
Toonen, R.F.2
Verhage, M.3
-
17
-
-
0029152786
-
Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos
-
Dominguez I., Itoh K., Sokol S.Y. Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos. Proc. Natl. Acad. Sci. U. S. A 1995, 92:8498-8502.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A
, vol.92
, pp. 8498-8502
-
-
Dominguez, I.1
Itoh, K.2
Sokol, S.Y.3
-
18
-
-
0027322674
-
Inhibitory effect of modified bafilomycins and concanamycins on P- and V-type adenosinetriphosphatases
-
Drose S., Bindseil K.U., Bowman E.J., Siebers A., Zeeck A., Altendorf K. Inhibitory effect of modified bafilomycins and concanamycins on P- and V-type adenosinetriphosphatases. Biochemistry 1993, 32:3902-3906.
-
(1993)
Biochemistry
, vol.32
, pp. 3902-3906
-
-
Drose, S.1
Bindseil, K.U.2
Bowman, E.J.3
Siebers, A.4
Zeeck, A.5
Altendorf, K.6
-
19
-
-
12944250922
-
Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A
-
Fang X., Yu S.X., Lu Y., Bast R.C., Woodgett J.R., Mills G.B. Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. Proc. Natl. Acad. Sci. U. S. A 2000, 97:11960-11965.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A
, vol.97
, pp. 11960-11965
-
-
Fang, X.1
Yu, S.X.2
Lu, Y.3
Bast, R.C.4
Woodgett, J.R.5
Mills, G.B.6
-
20
-
-
0023656594
-
Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3
-
Fiol C.J., Mahrenholz A.M., Wang Y., Roeske R.W., Roach P.J. Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3. J. Biol. Chem. 1987, 262:14042-14048.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 14042-14048
-
-
Fiol, C.J.1
Mahrenholz, A.M.2
Wang, Y.3
Roeske, R.W.4
Roach, P.J.5
-
21
-
-
34447626493
-
Glycogen synthase kinase 3: a key regulator of cellular fate
-
Forde J.E., Dale T.C. Glycogen synthase kinase 3: a key regulator of cellular fate. Cell Mol. Life Sci. 2007, 64:1930-1944.
-
(2007)
Cell Mol. Life Sci.
, vol.64
, pp. 1930-1944
-
-
Forde, J.E.1
Dale, T.C.2
-
22
-
-
78650469377
-
LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3beta in vivo and in vitro
-
Fu Z.Q., Yang Y., Song J., Jiang Q., Liu Z.C., Wang Q., Zhu L.Q., Wang J.Z., Tian Q. LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3beta in vivo and in vitro. J. Alzheimers. Dis. 2010, 21:1107-1117.
-
(2010)
J. Alzheimers. Dis.
, vol.21
, pp. 1107-1117
-
-
Fu, Z.Q.1
Yang, Y.2
Song, J.3
Jiang, Q.4
Liu, Z.C.5
Wang, Q.6
Zhu, L.Q.7
Wang, J.Z.8
Tian, Q.9
-
24
-
-
34250019938
-
Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice
-
Gomez-Sintes R., Hernandez F., Bortolozzi A., Artigas F., Avila J., Zaratin P., Gotteland J.P., Lucas J.J. Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice. EMBO J. 2007, 26:2743-2754.
-
(2007)
EMBO J.
, vol.26
, pp. 2743-2754
-
-
Gomez-Sintes, R.1
Hernandez, F.2
Bortolozzi, A.3
Artigas, F.4
Avila, J.5
Zaratin, P.6
Gotteland, J.P.7
Lucas, J.J.8
-
25
-
-
0034859101
-
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
-
Grimes C.A., Jope R.S. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog. Neurobiol. 2001, 65:391-426.
-
(2001)
Prog. Neurobiol.
, vol.65
, pp. 391-426
-
-
Grimes, C.A.1
Jope, R.S.2
-
26
-
-
0037189487
-
Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells
-
Hagen T., Di D.E., Culbert A.A., Reith A.D. Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells. J. Biol. Chem. 2002, 277:23330-23335.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23330-23335
-
-
Hagen, T.1
Di, D.E.2
Culbert, A.A.3
Reith, A.D.4
-
27
-
-
61849088424
-
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
-
Hanger D.P., Anderton B.H., Noble W. Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends Mol. Med. 2009, 15:112-119.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 112-119
-
-
Hanger, D.P.1
Anderton, B.H.2
Noble, W.3
-
28
-
-
0026487365
-
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase
-
Hanger D.P., Hughes K., Woodgett J.R., Brion J.P., Anderton B.H. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci. Lett. 1992, 147:58-62.
-
(1992)
Neurosci. Lett.
, vol.147
, pp. 58-62
-
-
Hanger, D.P.1
Hughes, K.2
Woodgett, J.R.3
Brion, J.P.4
Anderton, B.H.5
-
29
-
-
80052682729
-
Functional implications of glycogen synthase kinase-3-mediated tau phosphorylation
-
Hanger D.P., Noble W. Functional implications of glycogen synthase kinase-3-mediated tau phosphorylation. Int. J. Alzheimers Dis. 2011, 2011:352805.
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 352805
-
-
Hanger, D.P.1
Noble, W.2
-
31
-
-
33646497230
-
The plecomacrolide vacuolar-ATPase inhibitor bafilomycin, alters insulin signaling in MIN6 beta-cells
-
Hettiarachchi K.D., Zimmet P.Z., Myers M.A. The plecomacrolide vacuolar-ATPase inhibitor bafilomycin, alters insulin signaling in MIN6 beta-cells. Cell Biol. Toxicol. 2006, 22:169-181.
-
(2006)
Cell Biol. Toxicol.
, vol.22
, pp. 169-181
-
-
Hettiarachchi, K.D.1
Zimmet, P.Z.2
Myers, M.A.3
-
32
-
-
79959689333
-
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
-
Hoglinger G.U., Melhem N.M., Dickson D.W., Sleiman P.M., Wang L.S., Klei L., Rademakers R., de S.R., Litvan I., Riley D.E., van Swieten J.C., Heutink P., Wszolek Z.K., Uitti R.J., Vandrovcova J., Hurtig H.I., Gross R.G., Maetzler W., Goldwurm S., Tolosa E., Borroni B., Pastor P., Cantwell L.B., Han M.R., Dillman A., van der Brug M.P., Gibbs J.R., Cookson M.R., Hernandez D.G., Singleton A.B., Farrer M.J., Yu C.E., Golbe L.I., Revesz T., Hardy J., Lees A.J., Devlin B., Hakonarson H., Muller U., Schellenberg G.D. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nat. Genet. 2011, 43:699-705.
-
(2011)
Nat. Genet.
, vol.43
, pp. 699-705
-
-
Hoglinger, G.U.1
Melhem, N.M.2
Dickson, D.W.3
Sleiman, P.M.4
Wang, L.S.5
Klei, L.6
Rademakers, R.7
de, S.R.8
Litvan, I.9
Riley, D.E.10
van Swieten, J.C.11
Heutink, P.12
Wszolek, Z.K.13
Uitti, R.J.14
Vandrovcova, J.15
Hurtig, H.I.16
Gross, R.G.17
Maetzler, W.18
Goldwurm, S.19
Tolosa, E.20
Borroni, B.21
Pastor, P.22
Cantwell, L.B.23
Han, M.R.24
Dillman, A.25
van der Brug, M.P.26
Gibbs, J.R.27
Cookson, M.R.28
Hernandez, D.G.29
Singleton, A.B.30
Farrer, M.J.31
Yu, C.E.32
Golbe, L.I.33
Revesz, T.34
Hardy, J.35
Lees, A.J.36
Devlin, B.37
Hakonarson, H.38
Muller, U.39
Schellenberg, G.D.40
more..
-
33
-
-
65349093893
-
The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus
-
Hoozemans J.J.M., van Haastert E.S., Nijholt D.A.T., Rozemuller A.J.M., Eikelenboom P., Scheper W. The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus. Am. J. Pathol. 2009, 174:1241-1251.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 1241-1251
-
-
Hoozemans, J.J.M.1
van Haastert, E.S.2
Nijholt, D.A.T.3
Rozemuller, A.J.M.4
Eikelenboom, P.5
Scheper, W.6
-
34
-
-
24344489466
-
The unfolded protein response is activated in Alzheimer's disease
-
Hoozemans J.J.M., Veerhuis R., van Haastert E.S., Rozemuller J.M., Baas F., Eikelenboorn P., Scheper W. The unfolded protein response is activated in Alzheimer's disease. Acta Neuropathol. 2005, 110:165-172.
-
(2005)
Acta Neuropathol.
, vol.110
, pp. 165-172
-
-
Hoozemans, J.J.M.1
Veerhuis, R.2
van Haastert, E.S.3
Rozemuller, J.M.4
Baas, F.5
Eikelenboorn, P.6
Scheper, W.7
-
35
-
-
84866519178
-
Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
-
Inoue K., Rispoli J., Kaphzan H., Klann E., Chen E.I., Kim J., Komatsu M., Abeliovich A. Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway. Mol. Neurodegener. 2012, 7:48.
-
(2012)
Mol. Neurodegener.
, vol.7
, pp. 48
-
-
Inoue, K.1
Rispoli, J.2
Kaphzan, H.3
Klann, E.4
Chen, E.I.5
Kim, J.6
Komatsu, M.7
Abeliovich, A.8
-
36
-
-
0027255817
-
Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments
-
Ishiguro K., Shiratsuchi A., Sato S., Omori A., Arioka M., Kobayashi S., Uchida T., Imahori K. Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments. FEBS Lett. 1993, 325:167-172.
-
(1993)
FEBS Lett.
, vol.325
, pp. 167-172
-
-
Ishiguro, K.1
Shiratsuchi, A.2
Sato, S.3
Omori, A.4
Arioka, M.5
Kobayashi, S.6
Uchida, T.7
Imahori, K.8
-
37
-
-
0026731425
-
Tau protein kinase I converts normal tau protein into A68-like component of paired helical filaments
-
Ishiguro K., Takamatsu M., Tomizawa K., Omori A., Takahashi M., Arioka M., Uchida T., Imahori K. Tau protein kinase I converts normal tau protein into A68-like component of paired helical filaments. J Biol. Chem. 1992, 267:10897-10901.
-
(1992)
J Biol. Chem.
, vol.267
, pp. 10897-10901
-
-
Ishiguro, K.1
Takamatsu, M.2
Tomizawa, K.3
Omori, A.4
Takahashi, M.5
Arioka, M.6
Uchida, T.7
Imahori, K.8
-
38
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky D.J., Abdalla F.C., Abeliovich H., Abraham R.T., Acevedo-Arozena A., Adeli K., Agholme L., Agnello M., Agostinis P., Aguirre-Ghiso J.A., Ahn H.J., Ait-Mohamed O., Ait-Si-Ali S., Akematsu T., Akira S., Al-Younes H.M., Al-Zeer M.A., Albert M.L., Albin R.L., Alegre-Abarrategui J., Aleo M.F., Alirezaei M., Almasan A., Almonte-Becerril M., Amano A., Amaravadi R., Amarnath S., Amer A.O., Andrieu-Abadie N., Anantharam V., Ann D.K., Anoopkumar-Dukie S., Aoki H., Apostolova N., Auberger P., Baba M., Backues S.K., Baehrecke E.H., Bahr B.A., Bai X.Y., Bailly Y., Baiocchi R., Baldini G., Balduini W., Ballabio A., Bamber B.A., Bampton E.T., Banhegyi G., Bartholomew C.R., Bassham D.C., Bast R.C., Batoko H., Bay B.H., Beau I., Bechet D.M., Begley T.J., Behl C., Behrends C., Bekri S., Bellaire B., Bendall L.J., Benetti L., Berliocchi L., Bernardi H., Bernassola F., Besteiro S., Bhatia-Kissova I., Bi X., Biard-Piechaczyk M., Blum J.S., Boise L.H., Bonaldo P., Boone D.L., Bornhauser B.C., Bortoluci K.R., Bossis I., Bost F., Bourquin J.P., Boya P., Boyer-Guittaut M., Bozhkov P.V., Brady N.R., Brancolini C., Brech A., Brenman J.E., Brennand A., Bresnick E.H., Brest P., Bridges D., Bristol M.L., Brookes P.S., Brown E.J., Brumell J.H., Brunetti-Pierri N., Brunk U.T., Bulman D.E., Bultman S.J., Bultynck G., Burbulla L.F., Bursch W., Butchar J.P., Buzgariu W., Bydlowski S.P., Cadwell K., Cahova M., Cai D., Cai J., Cai Q., Calabretta B., Calvo-Garrido J., Camougrand N., Campanella M., Campos-Salinas J., Candi E., Cao L., Caplan A.B., Carding S.R., Cardoso S.M., Carew J.S., Carlin C.R., Carmignac V., Carneiro L.A., Carra S., Caruso R.A., Casari G., Casas C., Castino R., Cebollero E., Cecconi F., Celli J., Chaachouay H., Chae H.J., Chai C.Y., Chan D.C., Chan E.Y., Chang R.C., Che C.M., Chen C.C., Chen G.C., Chen G.Q., Chen M., Chen Q., Chen S.S., Chen W., Chen X., Chen X., Chen X., Chen Y.G., Chen Y., Chen Y., Chen Y.J., Chen Z., Cheng A., Cheng C.H., Cheng Y., Cheong H., Cheong J.H., Cherry S., Chess-Williams R., Cheung Z.H., Chevet E., Chiang H.L., Chiarelli R., Chiba T., Chin L.S., Chiou S.H., Chisari F.V., Cho C.H., Cho D.H., Choi A.M., Choi D., Choi K.S., Choi M.E., Chouaib S., Choubey D., Choubey V., Chu C.T., Chuang T.H., Chueh S.H., Chun T., Chwae Y.J., Chye M.L., Ciarcia R., Ciriolo M.R., Clague M.J., Clark R.S., Clarke P.G., Clarke R., Codogno P., Coller H.A., Colombo M.I., Comincini S., Condello M., Condorelli F., Cookson M.R., Coombs G.H., Coppens I., Corbalan R., Cossart P., Costelli P., Costes S., Coto-Montes A., Couve E., Coxon F.P., Cregg J.M., Crespo J.L., Cronje M.J., Cuervo A.M., Cullen J.J., Czaja M.J., D'Amelio M., Darfeuille-Michaud A., Davids L.M., Davies F.E., De F.M., de Groot J.F., de Haan C.A., De M.L., De M.A., De T.V., Debnath J., Degterev A., Dehay B., Delbridge L.M., Demarchi F., Deng Y.Z., Dengjel J., Dent P., Denton D., Deretic V., Desai S.D., Devenish R.J., Di G.M., Di P.G., Di P.C., Diaz-Araya G., Diaz-Laviada I., Diaz-Meco M.T., Diaz-Nido J., Dikic I., Dinesh-Kumar S.P., Ding W.X., Distelhorst C.W., Diwan A., Djavaheri-Mergny M., Dokudovskaya S., Dong Z., Dorsey F.C., Dosenko V., Dowling J.J., Doxsey S., Dreux M., Drew M.E., Duan Q., Duchosal M.A. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012, 8:445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
Agholme, L.7
Agnello, M.8
Agostinis, P.9
Aguirre-Ghiso, J.A.10
Ahn, H.J.11
Ait-Mohamed, O.12
Ait-Si-Ali, S.13
Akematsu, T.14
Akira, S.15
Al-Younes, H.M.16
Al-Zeer, M.A.17
Albert, M.L.18
Albin, R.L.19
Alegre-Abarrategui, J.20
Aleo, M.F.21
Alirezaei, M.22
Almasan, A.23
Almonte-Becerril, M.24
Amano, A.25
Amaravadi, R.26
Amarnath, S.27
Amer, A.O.28
Andrieu-Abadie, N.29
Anantharam, V.30
Ann, D.K.31
Anoopkumar-Dukie, S.32
Aoki, H.33
Apostolova, N.34
Auberger, P.35
Baba, M.36
Backues, S.K.37
Baehrecke, E.H.38
Bahr, B.A.39
Bai, X.Y.40
Bailly, Y.41
Baiocchi, R.42
Baldini, G.43
Balduini, W.44
Ballabio, A.45
Bamber, B.A.46
Bampton, E.T.47
Banhegyi, G.48
Bartholomew, C.R.49
Bassham, D.C.50
Bast, R.C.51
Batoko, H.52
Bay, B.H.53
Beau, I.54
Bechet, D.M.55
Begley, T.J.56
Behl, C.57
Behrends, C.58
Bekri, S.59
Bellaire, B.60
Bendall, L.J.61
Benetti, L.62
Berliocchi, L.63
Bernardi, H.64
Bernassola, F.65
Besteiro, S.66
Bhatia-Kissova, I.67
Bi, X.68
Biard-Piechaczyk, M.69
Blum, J.S.70
Boise, L.H.71
Bonaldo, P.72
Boone, D.L.73
Bornhauser, B.C.74
Bortoluci, K.R.75
Bossis, I.76
Bost, F.77
Bourquin, J.P.78
Boya, P.79
Boyer-Guittaut, M.80
Bozhkov, P.V.81
Brady, N.R.82
Brancolini, C.83
Brech, A.84
Brenman, J.E.85
Brennand, A.86
Bresnick, E.H.87
Brest, P.88
Bridges, D.89
Bristol, M.L.90
Brookes, P.S.91
Brown, E.J.92
Brumell, J.H.93
Brunetti-Pierri, N.94
Brunk, U.T.95
Bulman, D.E.96
Bultman, S.J.97
Bultynck, G.98
Burbulla, L.F.99
more..
-
39
-
-
0344245499
-
Expression analysis of glycogen synthase kinase-3 in human tissues
-
Lau K.F., Miller C.C., Anderton B.H., Shaw P.C. Expression analysis of glycogen synthase kinase-3 in human tissues. J. Pept. Res. 1999, 54:85-91.
-
(1999)
J. Pept. Res.
, vol.54
, pp. 85-91
-
-
Lau, K.F.1
Miller, C.C.2
Anderton, B.H.3
Shaw, P.C.4
-
40
-
-
77953913051
-
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
-
Lee J.H., Yu W.H., Kumar A., Lee S., Mohan P.S., Peterhoff C.M., Wolfe D.M., Martinez-Vicente M., Massey A.C., Sovak G., Uchiyama Y., Westaway D., Cuervo A.M., Nixon R.A. Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell 2010, 141:1146-1158.
-
(2010)
Cell
, vol.141
, pp. 1146-1158
-
-
Lee, J.H.1
Yu, W.H.2
Kumar, A.3
Lee, S.4
Mohan, P.S.5
Peterhoff, C.M.6
Wolfe, D.M.7
Martinez-Vicente, M.8
Massey, A.C.9
Sovak, G.10
Uchiyama, Y.11
Westaway, D.12
Cuervo, A.M.13
Nixon, R.A.14
-
41
-
-
79957663035
-
Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy
-
Lee S., Sato Y., Nixon R.A. Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy. J. Neurosci. 2011, 31:7817-7830.
-
(2011)
J. Neurosci.
, vol.31
, pp. 7817-7830
-
-
Lee, S.1
Sato, Y.2
Nixon, R.A.3
-
42
-
-
77049116286
-
Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology
-
Leroy K., Ando K., Heraud C., Yilmaz Z., Authelet M., Boeynaems J.M., Buee L., De D.R., Brion J.P. Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology. J. Alzheimers Dis. 2010, 19:705-719.
-
(2010)
J. Alzheimers Dis.
, vol.19
, pp. 705-719
-
-
Leroy, K.1
Ando, K.2
Heraud, C.3
Yilmaz, Z.4
Authelet, M.5
Boeynaems, J.M.6
Buee, L.7
De, D.R.8
Brion, J.P.9
-
43
-
-
0036942638
-
The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
-
Leroy K., Boutajangout A., Authelet M., Woodgett J.R., Anderton B.H., Brion J.P. The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathol. 2002, 103:91-99.
-
(2002)
Acta Neuropathol.
, vol.103
, pp. 91-99
-
-
Leroy, K.1
Boutajangout, A.2
Authelet, M.3
Woodgett, J.R.4
Anderton, B.H.5
Brion, J.P.6
-
44
-
-
0032955426
-
Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase
-
Lesort M., Jope R.S., Johnson G.V. Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase. J. Neurochem. 1999, 72:576-584.
-
(1999)
J. Neurochem.
, vol.72
, pp. 576-584
-
-
Lesort, M.1
Jope, R.S.2
Johnson, G.V.3
-
45
-
-
29244459434
-
Activation of glycogen synthase kinase-3 induces Alzheimer-like tau hyperphosphorylation in rat hippocampus slices in culture
-
Li X., Lu F., Tian Q., Yang Y., Wang Q., Wang J.Z. Activation of glycogen synthase kinase-3 induces Alzheimer-like tau hyperphosphorylation in rat hippocampus slices in culture. J. Neural Transm. 2006, 113:93-102.
-
(2006)
J. Neural Transm.
, vol.113
, pp. 93-102
-
-
Li, X.1
Lu, F.2
Tian, Q.3
Yang, Y.4
Wang, Q.5
Wang, J.Z.6
-
46
-
-
0029994754
-
Phosphorylation of tau by glycogen synthase kinase-3 beta in intact mammalian cells: the effects on the organization and stability of microtubules
-
Lovestone S., Hartley C.L., Pearce J., Anderton B.H. Phosphorylation of tau by glycogen synthase kinase-3 beta in intact mammalian cells: the effects on the organization and stability of microtubules. Neuroscience 1996, 73:1145-1157.
-
(1996)
Neuroscience
, vol.73
, pp. 1145-1157
-
-
Lovestone, S.1
Hartley, C.L.2
Pearce, J.3
Anderton, B.H.4
-
47
-
-
0028675873
-
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells
-
Lovestone S., Reynolds C.H., Latimer D., Davis D.R., Anderton B.H., Gallo J.M., Hanger D., Mulot S., Marquardt B., Stabel S. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol. 1994, 4:1077-1086.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1077-1086
-
-
Lovestone, S.1
Reynolds, C.H.2
Latimer, D.3
Davis, D.R.4
Anderton, B.H.5
Gallo, J.M.6
Hanger, D.7
Mulot, S.8
Marquardt, B.9
Stabel, S.10
-
48
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
-
Lucas J.J., Hernandez F., Gomez-Ramos P., Moran M.A., Hen R., Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J. 2001, 20:27-39.
-
(2001)
EMBO J.
, vol.20
, pp. 27-39
-
-
Lucas, J.J.1
Hernandez, F.2
Gomez-Ramos, P.3
Moran, M.A.4
Hen, R.5
Avila, J.6
-
49
-
-
79959222357
-
Deconstructing GSK-3: the fine regulation of its activity
-
Medina M., Wandosell F. Deconstructing GSK-3: the fine regulation of its activity. Int. J. Alzheimers Dis. 2011, 2011:479249.
-
(2011)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 479249
-
-
Medina, M.1
Wandosell, F.2
-
51
-
-
79955804227
-
Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease
-
Nijholt D.A., de Graaf T.R., van Haastert E.S., Oliveira A.O., Berkers C.R., Zwart R., Ovaa H., Baas F., Hoozemans J.J., Scheper W. Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease. Cell Death Differ. 2011, 18:1071-1081.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 1071-1081
-
-
Nijholt, D.A.1
de Graaf, T.R.2
van Haastert, E.S.3
Oliveira, A.O.4
Berkers, C.R.5
Zwart, R.6
Ovaa, H.7
Baas, F.8
Hoozemans, J.J.9
Scheper, W.10
-
52
-
-
79957947433
-
Removing protein aggregates: the role of proteolysis in neurodegeneration
-
Nijholt D.A., De K.L., Elfrink H.L., Hoozemans J.J., Scheper W. Removing protein aggregates: the role of proteolysis in neurodegeneration. Curr. Med. Chem. 2011, 18:2459-2476.
-
(2011)
Curr. Med. Chem.
, vol.18
, pp. 2459-2476
-
-
Nijholt, D.A.1
De, K.L.2
Elfrink, H.L.3
Hoozemans, J.J.4
Scheper, W.5
-
53
-
-
84858000638
-
The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies
-
Nijholt D.A.T., van Haastert E.S., Rozemuller A.J.M., Scheper W., Hoozemans J.J.M. The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies. J. Pathol. 2011, 226:693-702.
-
(2011)
J. Pathol.
, vol.226
, pp. 693-702
-
-
Nijholt, D.A.T.1
van Haastert, E.S.2
Rozemuller, A.J.M.3
Scheper, W.4
Hoozemans, J.J.M.5
-
54
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study
-
Nixon R.A., Wegiel J., Kumar A., Yu W.H., Peterhoff C., Cataldo A., Cuervo A.M. Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J. Neuropathol. Exp. Neurol. 2005, 64:113-122.
-
(2005)
J. Neuropathol. Exp. Neurol.
, vol.64
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
Yu, W.H.4
Peterhoff, C.5
Cataldo, A.6
Cuervo, A.M.7
-
55
-
-
21044449225
-
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
-
Noble W., Planel E., Zehr C., Olm V., Meyerson J., Suleman F., Gaynor K., Wang L., LaFrancois J., Feinstein B., Burns M., Krishnamurthy P., Wen Y., Bhat R., Lewis J., Dickson D., Duff K. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl. Acad. Sci. U. S. A 2005, 102:6990-6995.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 6990-6995
-
-
Noble, W.1
Planel, E.2
Zehr, C.3
Olm, V.4
Meyerson, J.5
Suleman, F.6
Gaynor, K.7
Wang, L.8
LaFrancois, J.9
Feinstein, B.10
Burns, M.11
Krishnamurthy, P.12
Wen, Y.13
Bhat, R.14
Lewis, J.15
Dickson, D.16
Duff, K.17
-
56
-
-
49349110485
-
Pre-assembled tau filaments phosphorylated by GSK-3b form large tangle-like structures
-
Rankin C.A., Sun Q., Gamblin T.C. Pre-assembled tau filaments phosphorylated by GSK-3b form large tangle-like structures. Neurobiol. Dis. 2008, 31:368-377.
-
(2008)
Neurobiol. Dis.
, vol.31
, pp. 368-377
-
-
Rankin, C.A.1
Sun, Q.2
Gamblin, T.C.3
-
57
-
-
0032212348
-
An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts
-
Ryves W.J., Fryer L., Dale T., Harwood A.J. An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts. Anal. Biochem. 1998, 264:124-127.
-
(1998)
Anal. Biochem.
, vol.264
, pp. 124-127
-
-
Ryves, W.J.1
Fryer, L.2
Dale, T.3
Harwood, A.J.4
-
58
-
-
10444226462
-
ER stress and the unfolded protein response
-
Schroder M., Kaufman R.J. ER stress and the unfolded protein response. Mutat. Res. 2005, 569:29-63.
-
(2005)
Mutat. Res.
, vol.569
, pp. 29-63
-
-
Schroder, M.1
Kaufman, R.J.2
-
59
-
-
68149150844
-
A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo
-
Sereno L., Coma M., Rodriguez M., Sanchez-Ferrer P., Sanchez M.B., Gich I., Agullo J.M., Perez M., Avila J., Guardia-Laguarta C., Clarimon J., Lleo A., Gomez-Isla T. A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo. Neurobiol. Dis. 2009, 35:359-367.
-
(2009)
Neurobiol. Dis.
, vol.35
, pp. 359-367
-
-
Sereno, L.1
Coma, M.2
Rodriguez, M.3
Sanchez-Ferrer, P.4
Sanchez, M.B.5
Gich, I.6
Agullo, J.M.7
Perez, M.8
Avila, J.9
Guardia-Laguarta, C.10
Clarimon, J.11
Lleo, A.12
Gomez-Isla, T.13
-
60
-
-
0037160134
-
Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation
-
Song L., De S.P., Jope R.S. Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. J. Biol. Chem. 2002, 277:44701-44708.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44701-44708
-
-
Song, L.1
De, S.P.2
Jope, R.S.3
-
61
-
-
0035127310
-
Starvation-induced lysosomal degradation of aldolase B requires glutamine 111 in a signal sequence for chaperone-mediated transport
-
Susan P.P., Dunn W.A. Starvation-induced lysosomal degradation of aldolase B requires glutamine 111 in a signal sequence for chaperone-mediated transport. J. Cell Physiol. 2001, 187:48-58.
-
(2001)
J. Cell Physiol.
, vol.187
, pp. 48-58
-
-
Susan, P.P.1
Dunn, W.A.2
-
62
-
-
0031695652
-
Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons
-
Takashima A., Honda T., Yasutake K., Michel G., Murayama O., Murayama M., Ishiguro K., Yamaguchi H. Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons. Neurosci. Res. 1998, 31:317-323.
-
(1998)
Neurosci. Res.
, vol.31
, pp. 317-323
-
-
Takashima, A.1
Honda, T.2
Yasutake, K.3
Michel, G.4
Murayama, O.5
Murayama, M.6
Ishiguro, K.7
Yamaguchi, H.8
-
63
-
-
60549104999
-
Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling
-
Tang Q., Cai J., Shen D., Bian Z., Yan L., Wang Y.X., Lan J., Zhuang G.Q., Ma W.Z., Wang W. Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling. J. Mol. Med. (Berl) 2009, 87:249-260.
-
(2009)
J. Mol. Med. (Berl)
, vol.87
, pp. 249-260
-
-
Tang, Q.1
Cai, J.2
Shen, D.3
Bian, Z.4
Yan, L.5
Wang, Y.X.6
Lan, J.7
Zhuang, G.Q.8
Ma, W.Z.9
Wang, W.10
-
64
-
-
33744985455
-
Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo
-
Unterberger U., Hoftberger R., Gelpi E., Flicker H., Budka H., Voigtlander T. Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo. J. Neuropathol. Exp. Neurol. 2006, 65:348-357.
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, pp. 348-357
-
-
Unterberger, U.1
Hoftberger, R.2
Gelpi, E.3
Flicker, H.4
Budka, H.5
Voigtlander, T.6
-
65
-
-
0029998294
-
Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation
-
Wagner U., Utton M., Gallo J.M., Miller C.C. Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation. J. Cell Sci. 1996, 109:1537-1543.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 1537-1543
-
-
Wagner, U.1
Utton, M.2
Gallo, J.M.3
Miller, C.C.4
-
66
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/factor A
-
Woodgett J.R. Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J. 1990, 9:2431-2438.
-
(1990)
EMBO J.
, vol.9
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
67
-
-
0036281126
-
Expression of glycogen synthase kinase-3 isoforms in mouse tissues and their transcription in the brain
-
Yao H.B., Shaw P.C., Wong C.C., Wan D.C. Expression of glycogen synthase kinase-3 isoforms in mouse tissues and their transcription in the brain. J. Chem. Neuroanat. 2002, 23:291-297.
-
(2002)
J. Chem. Neuroanat.
, vol.23
, pp. 291-297
-
-
Yao, H.B.1
Shaw, P.C.2
Wong, C.C.3
Wan, D.C.4
-
68
-
-
33749579383
-
Endoplasmic reticulum stress triggers autophagy
-
Yorimitsu T., Nair U., Yang Z., Klionsky D.J. Endoplasmic reticulum stress triggers autophagy. J. Biol. Chem. 2006, 281:30299-30304.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30299-30304
-
-
Yorimitsu, T.1
Nair, U.2
Yang, Z.3
Klionsky, D.J.4
|