-
1
-
-
0022365608
-
The distribution of tau in the mammalian central nervous system
-
Binder LI, Frankfurter A, Rebhun LI (1985) The distribution of tau in the mammalian central nervous system. J Cell Biol 101: 1371-1378.
-
(1985)
J Cell Biol
, vol.101
, pp. 1371-1378
-
-
Binder, L.I.1
Frankfurter, A.2
Rebhun, L.I.3
-
2
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA (1989) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3: 519-526.
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
3
-
-
0033532318
-
Phylogenetic diversity of the expression of the microtubule-associated protein tau: Implications for neurodegenerative disorders
-
Janke C, Beck M, Stahl T, Holzer M, Brauer K, et al. (1999) Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders. Brain Res Mol Brain Res 68: 119-128.
-
(1999)
Brain Res Mol Brain Res
, vol.68
, pp. 119-128
-
-
Janke, C.1
Beck, M.2
Stahl, T.3
Holzer, M.4
Brauer, K.5
-
4
-
-
33847653807
-
Expression of embryonic tau protein isoforms persist during adult neurogenesis in the hippocampus
-
Bullmann T, de Silva R, Holzer M, Mori H, Arendt T (2007) Expression of embryonic tau protein isoforms persist during adult neurogenesis in the hippocampus. Hippocampus 17: 98-102.
-
(2007)
Hippocampus
, vol.17
, pp. 98-102
-
-
Bullmann, T.1
de Silva, R.2
Holzer, M.3
Mori, H.4
Arendt, T.5
-
6
-
-
0017758306
-
Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly
-
Cleveland DW, Hwo SY, Kirschner MW (1977) Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly. J Mol Biol 116: 227-247.
-
(1977)
J Mol Biol
, vol.116
, pp. 227-247
-
-
Cleveland, D.W.1
Hwo, S.Y.2
Kirschner, M.W.3
-
8
-
-
0033042978
-
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation
-
Dayanandan R, Van SM, Mack TG, Ko L, Yen SH, et al. (1999) Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation. FEBS Lett 446: 228-232.
-
(1999)
FEBS Lett
, vol.446
, pp. 228-232
-
-
Dayanandan, R.1
Van, S.M.2
Mack, T.G.3
Ko, L.4
Yen, S.H.5
-
9
-
-
0026595846
-
Tau proteins of Alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms
-
Goedert M, Spillantini MG, Cairns NJ, Crowther RA (1992) Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 8: 159-168.
-
(1992)
Neuron
, vol.8
, pp. 159-168
-
-
Goedert, M.1
Spillantini, M.G.2
Cairns, N.J.3
Crowther, R.A.4
-
10
-
-
0027308924
-
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
-
Bramblett GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, et al. (1993) Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron 10: 1089-1099.
-
(1993)
Neuron
, vol.10
, pp. 1089-1099
-
-
Bramblett, G.T.1
Goedert, M.2
Jakes, R.3
Merrick, S.E.4
Trojanowski, J.Q.5
-
11
-
-
0027338266
-
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
-
Biernat J, Gustke N, Drewes G, Mandelkow EM, Mandelkow E (1993) Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding. Neuron 11: 153-163.
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.M.4
Mandelkow, E.5
-
12
-
-
17044461433
-
The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: Implications for Alzheimer's disease
-
Illenberger S, Zheng-Fischhofer Q, Preuss U, Stamer K, Baumann K, et al. (1998) The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease. Mol Biol Cell 9: 1495-1512.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 1495-1512
-
-
Illenberger, S.1
Zheng-Fischhofer, Q.2
Preuss, U.3
Stamer, K.4
Baumann, K.5
-
13
-
-
33748372746
-
Tauopathies: Classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau
-
Williams DR (2006) Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau. Intern Med J 36: 652-660.
-
(2006)
Intern Med J
, vol.36
, pp. 652-660
-
-
Williams, D.R.1
-
14
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, et al. (1986) Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci USA 83: 4913-4917.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
-
15
-
-
33646365908
-
Hyperphosphorylation of Tau Induces Local Polyproline II Helix
-
Bielska AA, Zondlo NJ (2006) Hyperphosphorylation of Tau Induces Local Polyproline II Helix. Biochemistry 45: 5527-5537.
-
(2006)
Biochemistry
, vol.45
, pp. 5527-5537
-
-
Bielska, A.A.1
Zondlo, N.J.2
-
16
-
-
34748824095
-
Phosphorylation modulates the local conformation and self-aggregation ability of a peptide from the fourth tau microtubule-binding repeat
-
Du JT, Yu CH, Zhou LX, Wu WH, Lei P, et al. (2007) Phosphorylation modulates the local conformation and self-aggregation ability of a peptide from the fourth tau microtubule-binding repeat. FEBS J 274: 5012-5020.
-
(2007)
FEBS J
, vol.274
, pp. 5012-5020
-
-
Du, J.T.1
Yu, C.H.2
Zhou, L.X.3
Wu, W.H.4
Lei, P.5
-
17
-
-
0029999787
-
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules
-
Alonso AC, Grundke-Iqbal I, Iqbal K (1996) Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. Nat Med 2: 783-787.
-
(1996)
Nat Med
, vol.2
, pp. 783-787
-
-
Alonso, A.C.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
18
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/ straight filaments
-
Alonso A, Zaidi T, Novak M, Grundke-Iqbal I, Iqbal K (2001) Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/ straight filaments. Proc Natl Acad Sci USA 98: 6923-6928.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6923-6928
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
19
-
-
22244443877
-
Hyperphosphorylation-induced self assembly of murine tau: A comparison with human tau
-
Chohan MO, Haque N, Alonso A, El AE, Grundke-Iqbal I, et al. (2005) Hyperphosphorylation-induced self assembly of murine tau: a comparison with human tau. J Neural Transm 112: 1035-1047.
-
(2005)
J Neural Transm
, vol.112
, pp. 1035-1047
-
-
Chohan, M.O.1
Haque, N.2
Alonso, A.3
El, A.E.4
Grundke-Iqbal, I.5
-
20
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
-
Schneider A, Biernat J, von Bergen M, Mandelkow E, Mandelkow EM (1999) Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments. Biochemistry 38: 3549-3558.
-
(1999)
Biochemistry
, vol.38
, pp. 3549-3558
-
-
Schneider, A.1
Biernat, J.2
von Bergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
21
-
-
1642280378
-
Pseudophosphorylation of tau protein alters its ability for self-aggregation
-
Haase C, Stieler JT, Arendt T, Holzer M (2004) Pseudophosphorylation of tau protein alters its ability for self-aggregation. J Neurochem 88: 1509-1520.
-
(2004)
J Neurochem
, vol.88
, pp. 1509-1520
-
-
Haase, C.1
Stieler, J.T.2
Arendt, T.3
Holzer, M.4
-
22
-
-
33745827715
-
Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation
-
Ding H, Matthews TA, Johnson GV (2006) Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation. J Biol Chem 281: 19107-19114.
-
(2006)
J Biol Chem
, vol.281
, pp. 19107-19114
-
-
Ding, H.1
Matthews, T.A.2
Johnson, G.V.3
-
23
-
-
36949040819
-
Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation
-
Liu F, Li B, Tung EJ, Grundke-Iqbal I, Iqbal K, et al. (2007) Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation. Eur J Neurosci 26: 3429-3436.
-
(2007)
Eur J Neurosci
, vol.26
, pp. 3429-3436
-
-
Liu, F.1
Li, B.2
Tung, E.J.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
24
-
-
0042125603
-
Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals
-
Arendt T, Stieler J, Strijkstra AM, Hut RA, Rüdiger J, et al. (2003) Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals. J Neurosci 23: 6972-6981.
-
(2003)
J Neurosci
, vol.23
, pp. 6972-6981
-
-
Arendt, T.1
Stieler, J.2
Strijkstra, A.M.3
Hut, R.A.4
Rüdiger, J.5
-
25
-
-
10944224599
-
Can tau filaments be both physiologically beneficial and toxic?
-
King ME (2005) Can tau filaments be both physiologically beneficial and toxic? Biochim Biophys Acta 1739: 260-267.
-
(2005)
Biochim Biophys Acta
, vol.1739
, pp. 260-267
-
-
King, M.E.1
-
26
-
-
17044435830
-
Tau phosphorylation in Alzheimer's disease: Pathogen or protector?
-
Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, et al. (2005) Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends Mol Med 11: 164-169.
-
(2005)
Trends Mol Med
, vol.11
, pp. 164-169
-
-
Lee, H.G.1
Perry, G.2
Moreira, P.I.3
Garrett, M.R.4
Liu, Q.5
-
27
-
-
33846203763
-
Hibernation model of tau phosphorylation in hamsters: Selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease
-
Härtig W, Stieler J, Boerema AS, Wolf J, Schmidt U, et al. (2007) Hibernation model of tau phosphorylation in hamsters: selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease. Eur J Neurosci 25: 69-80.
-
(2007)
Eur J Neurosci
, vol.25
, pp. 69-80
-
-
Härtig, W.1
Stieler, J.2
Boerema, A.S.3
Wolf, J.4
Schmidt, U.5
-
28
-
-
67349275848
-
Activity state profile of tau kinases in hibernating animals
-
In: Lovegrove BG, McKechnie AE, eds., University of KwaZulu-Natal, Pietermaritzburg
-
Stieler JT, Boerema AS, Bullmann T, Kohl F, Strijkstra AM, et al. (2008) Activity state profile of tau kinases in hibernating animals. In: Lovegrove BG, McKechnie AE, eds. Hypometabolism in animals: hibernation, torpor and cryobiology University of KwaZulu-Natal, Pietermaritzburg. pp 133-142.
-
(2008)
Hypometabolism in animals: Hibernation, torpor and cryobiology
, pp. 133-142
-
-
Stieler, J.T.1
Boerema, A.S.2
Bullmann, T.3
Kohl, F.4
Strijkstra, A.M.5
-
29
-
-
44649165063
-
Physiological regulation of tau phosphorylation during hibernation
-
Su B, Wang X, Drew KL, Perry G, Smith MA, et al. (2008) Physiological regulation of tau phosphorylation during hibernation. J Neurochem 105: 2098-2108.
-
(2008)
J Neurochem
, vol.105
, pp. 2098-2108
-
-
Su, B.1
Wang, X.2
Drew, K.L.3
Perry, G.4
Smith, M.A.5
-
30
-
-
0026574156
-
Hibernation-induced structural changes in synaptic contacts between mossy fibres and hippocampal pyramidal neurons
-
Popov VI, Bocharova LS (1992) Hibernation-induced structural changes in synaptic contacts between mossy fibres and hippocampal pyramidal neurons. Neuroscience 48: 53-62.
-
(1992)
Neuroscience
, vol.48
, pp. 53-62
-
-
Popov, V.I.1
Bocharova, L.S.2
-
31
-
-
0038359293
-
Hippocampal synaptophysin immunoreactivity is reduced during natural hypothermia in ground squirrels
-
Strijkstra AM, Hut RA, de Wilde MC, Stieler J, Van der Zee EA (2003) Hippocampal synaptophysin immunoreactivity is reduced during natural hypothermia in ground squirrels. Neurosci Lett 344: 29-32.
-
(2003)
Neurosci Lett
, vol.344
, pp. 29-32
-
-
Strijkstra, A.M.1
Hut, R.A.2
de Wilde, M.C.3
Stieler, J.4
van der Zee, E.A.5
-
34
-
-
0034992288
-
Hibernation effects on memory in European ground squirrels (Spermophilus citellus)
-
Millesi E, Prossinger H, Dittami JP, Fieder M (2001) Hibernation effects on memory in European ground squirrels (Spermophilus citellus). J Biol Rhythms 16: 264-271.
-
(2001)
J Biol Rhythms
, vol.16
, pp. 264-271
-
-
Millesi, E.1
Prossinger, H.2
Dittami, J.P.3
Fieder, M.4
-
35
-
-
0030936599
-
Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau
-
Jicha GA, Bowser R, Kazam IG, Davies P (1997) Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau. J Neurosci Res 48: 128-132.
-
(1997)
J Neurosci Res
, vol.48
, pp. 128-132
-
-
Jicha, G.A.1
Bowser, R.2
Kazam, I.G.3
Davies, P.4
-
36
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
37
-
-
3543017385
-
Natural hypometabolism during hibernation and daily torpor in mammals
-
Heldmaier G, Ortmann S, Elvert R (2004) Natural hypometabolism during hibernation and daily torpor in mammals. Respir Physiol Neurobiol 141: 317-329.
-
(2004)
Respir Physiol Neurobiol
, vol.141
, pp. 317-329
-
-
Heldmaier, G.1
Ortmann, S.2
Elvert, R.3
-
38
-
-
0024475071
-
Freeze avoidance in a mammal: Body temperatures below 0 degree C in an Arctic hibernator
-
Barnes BM (1989) Freeze avoidance in a mammal: body temperatures below 0 degree C in an Arctic hibernator. Science 244: 1593-1595.
-
(1989)
Science
, vol.244
, pp. 1593-1595
-
-
Barnes, B.M.1
-
40
-
-
0025764831
-
Warming up for sleep? Ground squirrels sleep during arousals from hibernation
-
Daan S, Barnes BM, Strijkstra AM (1991) Warming up for sleep? Ground squirrels sleep during arousals from hibernation. Neurosci Lett 128: 265-268.
-
(1991)
Neurosci Lett
, vol.128
, pp. 265-268
-
-
Daan, S.1
Barnes, B.M.2
Strijkstra, A.M.3
-
41
-
-
0026704403
-
Central role for differential gene expression in mammalian hibernation
-
Srere HK, Wang LC, Martin SL (1992) Central role for differential gene expression in mammalian hibernation. Proc Natl Acad Sci USA 89: 7119-7123.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7119-7123
-
-
Srere, H.K.1
Wang, L.C.2
Martin, S.L.3
-
42
-
-
13844299011
-
The evolution of endothermy and its diversity in mammals and birds
-
Grigg GC, Beard LA, Augee ML (2004) The evolution of endothermy and its diversity in mammals and birds. Physiol Biochem Zool 77: 982-997.
-
(2004)
Physiol Biochem Zool
, vol.77
, pp. 982-997
-
-
Grigg, G.C.1
Beard, L.A.2
Augee, M.L.3
-
43
-
-
0033886557
-
Effects of ambient temperature on metabolic rate, respiratory quotient, and torpor in an arctic hibernator
-
Buck CL, Barnes BM (2000) Effects of ambient temperature on metabolic rate, respiratory quotient, and torpor in an arctic hibernator. Am J Physiol Regul Integr Comp Physiol 279: R255-R262.
-
(2000)
Am J Physiol Regul Integr Comp Physiol
, vol.279
-
-
Buck, C.L.1
Barnes, B.M.2
-
44
-
-
0015887549
-
Winter sleep in the black bear. A physiologic and metabolic marvel
-
Nelson RA (1973) Winter sleep in the black bear. A physiologic and metabolic marvel. Mayo Clin Proc 48: 733-737.
-
(1973)
Mayo Clin Proc
, vol.48
, pp. 733-737
-
-
Nelson, R.A.1
-
45
-
-
0016659944
-
Nitrogen metabolism in bears: Urea metabolism in summer starvation and in winter sleep and role of urinary bladder in water and nitrogen conservation
-
Nelson RA, Jones JD, Wahner HW (1975) Nitrogen metabolism in bears: urea metabolism in summer starvation and in winter sleep and role of urinary bladder in water and nitrogen conservation. Mayo Clin Proc 50: 141-146.
-
(1975)
Mayo Clin Proc
, vol.50
, pp. 141-146
-
-
Nelson, R.A.1
Jones, J.D.2
Wahner, H.W.3
-
46
-
-
77952905816
-
Hibernation in black bears: Energetics and thermoregulation
-
Tøien Ø, Barnes BM, Blake J, Grahn D, Heller HC, et al. (1999) Hibernation in black bears: Energetics and thermoregulation. FASEB J 13: A740.
-
(1999)
FASEB J
, vol.13
-
-
Tøien, O.1
Barnes, B.M.2
Blake, J.3
Grahn, D.4
Heller, H.C.5
-
47
-
-
0034932780
-
Temporal organisation of hibernation in wild-type and tau mutant Syrian hamsters
-
Oklejewicz M, Daan S, Strijkstra AM (2001) Temporal organisation of hibernation in wild-type and tau mutant Syrian hamsters. J Comp Physiol [B] 171: 431-439.
-
(2001)
J Comp Physiol [B]
, vol.171
, pp. 431-439
-
-
Oklejewicz, M.1
Daan, S.2
Strijkstra, A.M.3
-
48
-
-
0003130332
-
The oxygen consumption and temperature regulation of hibernating hamsters
-
Lyman CP (1948) The oxygen consumption and temperature regulation of hibernating hamsters. J Exp Zool 109: 55-78.
-
(1948)
J Exp Zool
, vol.109
, pp. 55-78
-
-
Lyman, C.P.1
-
49
-
-
0032716550
-
Starvation induces tau hyperphosphorylation in mouse brain: Implications for Alzheimer's disease
-
Yanagisawa M, Planel E, Ishiguro K, Fujita SC (1999) Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease. FEBS Lett 461: 329-333.
-
(1999)
FEBS Lett
, vol.461
, pp. 329-333
-
-
Yanagisawa, M.1
Planel, E.2
Ishiguro, K.3
Fujita, S.C.4
-
50
-
-
0035823496
-
Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse
-
Planel E, Yasutake K, Fujita SC, Ishiguro K (2001) Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3 beta and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation in the hippocampus of starved mouse. J Biol Chem 276: 34298-34306.
-
(2001)
J Biol Chem
, vol.276
, pp. 34298-34306
-
-
Planel, E.1
Yasutake, K.2
Fujita, S.C.3
Ishiguro, K.4
-
51
-
-
12144289492
-
Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: Implications for Alzheimer's disease
-
Planel E, Miyasaka T, Launey T, Chui DH, Tanemura K, et al. (2004) Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease. J Neurosci 24: 2401-2411.
-
(2004)
J Neurosci
, vol.24
, pp. 2401-2411
-
-
Planel, E.1
Miyasaka, T.2
Launey, T.3
Chui, D.H.4
Tanemura, K.5
-
52
-
-
33847174544
-
Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain
-
Ikeda Y, Ishiguro K, Fujita SC (2007) Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain. FEBS Lett 581: 891-897.
-
(2007)
FEBS Lett
, vol.581
, pp. 891-897
-
-
Ikeda, Y.1
Ishiguro, K.2
Fujita, S.C.3
-
53
-
-
33947536100
-
Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia
-
Planel E, Richter KE, Nolan CE, Finley JE, Liu L, et al. (2007) Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia. J Neurosci 27: 3090-3097.
-
(2007)
J Neurosci
, vol.27
, pp. 3090-3097
-
-
Planel, E.1
Richter, K.E.2
Nolan, C.E.3
Finley, J.E.4
Liu, L.5
-
54
-
-
0037472631
-
Stress-induced hyperphosphorylation of tau in the mouse brain
-
Okawa Y, Ishiguro K, Fujita SC (2003) Stress-induced hyperphosphorylation of tau in the mouse brain. FEBS Lett 535: 183-189.
-
(2003)
FEBS Lett
, vol.535
, pp. 183-189
-
-
Okawa, Y.1
Ishiguro, K.2
Fujita, S.C.3
-
55
-
-
43249124363
-
Microtubule-associated protein tau in development, degeneration and protection of neurons
-
Wang JZ, Liu F (2008) Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 85: 148-175.
-
(2008)
Prog Neurobiol
, vol.85
, pp. 148-175
-
-
Wang, J.Z.1
Liu, F.2
-
56
-
-
0032451407
-
Postmortem changes in the phosphorylation state of tau-protein in the rat brain
-
Gärtner U, Janke C, Holzer M, Vanmechelen E, Arendt T (1998) Postmortem changes in the phosphorylation state of tau-protein in the rat brain. Neurobiol Aging 19: 535-543.
-
(1998)
Neurobiol Aging
, vol.19
, pp. 535-543
-
-
Gärtner, U.1
Janke, C.2
Holzer, M.3
Vanmechelen, E.4
Arendt, T.5
-
57
-
-
0026758096
-
Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes
-
Mercken M, Vandermeeren M, Lübke U, Six J, Boons J, et al. (1992) Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes. Acta Neuropathol 84: 265-272.
-
(1992)
Acta Neuropathol
, vol.84
, pp. 265-272
-
-
Mercken, M.1
Vandermeeren, M.2
Lübke, U.3
Six, J.4
Boons, J.5
-
58
-
-
0027984739
-
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: Identification of phosphorylation sites in tau protein
-
Goedert M, Jakes R, Crowther RA, Cohen P, Vanmechelen E, et al. (1994) Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. Biochem J 301: 871-877.
-
(1994)
Biochem J
, vol.301
, pp. 871-877
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
Cohen, P.4
Vanmechelen, E.5
-
59
-
-
33748715165
-
Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope
-
Yoshida H, Goedert M (2006) Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope. J Neurochem 99: 154-164.
-
(2006)
J Neurochem
, vol.99
, pp. 154-164
-
-
Yoshida, H.1
Goedert, M.2
-
60
-
-
33748752882
-
The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation
-
Plattner F, Angelo M, Giese KP (2006) The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation. J Biol Chem 281: 25457-25465.
-
(2006)
J Biol Chem
, vol.281
, pp. 25457-25465
-
-
Plattner, F.1
Angelo, M.2
Giese, K.P.3
-
61
-
-
0033613199
-
Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation
-
Sharma P, Sharma M, Amin ND, Albers RW, Pant HC (1999) Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation. Proc Natl Acad Sci USA 96: 11156-11160.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11156-11160
-
-
Sharma, P.1
Sharma, M.2
Amin, N.D.3
Albers, R.W.4
Pant, H.C.5
-
62
-
-
61849108724
-
PHF-like tau phosphorylation in mammalian hibernation is not associated with p25- formation
-
Stieler JT, Bullmann T, Kohl F, Barnes BM, Arendt T (2009) PHF-like tau phosphorylation in mammalian hibernation is not associated with p25- formation. J Neural Transm 116: 345-350.
-
(2009)
J Neural Transm
, vol.116
, pp. 345-350
-
-
Stieler, J.T.1
Bullmann, T.2
Kohl, F.3
Barnes, B.M.4
Arendt, T.5
-
63
-
-
21844440325
-
MAPKs are differentially modulated in arctic ground squirrels during hibernation
-
Zhu X, Smith MA, Perry G, Wang Y, Ross AP, et al. (2005) MAPKs are differentially modulated in arctic ground squirrels during hibernation. J Neurosci Res 80: 862-868.
-
(2005)
J Neurosci Res
, vol.80
, pp. 862-868
-
-
Zhu, X.1
Smith, M.A.2
Perry, G.3
Wang, Y.4
Ross, A.P.5
-
64
-
-
11144275963
-
Mitogen-activated protein kinases and selected downstream targets display organ-specific responses in the hibernating ground squirrel
-
MacDonald JA, Storey KB (2005) Mitogen-activated protein kinases and selected downstream targets display organ-specific responses in the hibernating ground squirrel. Int J Biochem Cell Biol 37: 679-691.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 679-691
-
-
McDonald, J.A.1
Storey, K.B.2
-
65
-
-
0029970342
-
Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E
-
Reiman EM, Caselli RJ, Yun LS, Chen K, Bandy D, et al. (1996) Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. N Engl J Med 334: 752-758.
-
(1996)
N Engl J Med
, vol.334
, pp. 752-758
-
-
Reiman, E.M.1
Caselli, R.J.2
Yun, L.S.3
Chen, K.4
Bandy, D.5
-
66
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
Small GW, Ercoli LM, Silverman DH, Huang SC, Komo S, et al. (2000) Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci USA 97: 6037-6042.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.3
Huang, S.C.4
Komo, S.5
-
67
-
-
0347719366
-
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
-
Reiman EM, Chen K, Alexander GE, Caselli RJ, Bandy D, et al. (2004) Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Natl Acad Sci USA 101: 284-289.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 284-289
-
-
Reiman, E.M.1
Chen, K.2
Alexander, G.E.3
Caselli, R.J.4
Bandy, D.5
-
68
-
-
0035845499
-
Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2- deoxy-D-glucose/poitron-emission tomography (FDG/PET)
-
de Leon MJ, Convit A, Wolf OT, Tarshish CY, DeSanti S, et al. (2001) Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2- deoxy-D-glucose/poitron-emission tomography (FDG/PET). Proc Natl Acad Sci USA 98: 10966-10971.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10966-10971
-
-
de Leon, M.J.1
Convit, A.2
Wolf, O.T.3
Tarshish, C.Y.4
DeSanti, S.5
-
69
-
-
0036454057
-
Functional brain imaging in the dementias: Role in early detection, differential diagnosis, and longitudinal studies
-
Devous MDS (2002) Functional brain imaging in the dementias: role in early detection, differential diagnosis, and longitudinal studies. Eur J Nucl Med Mol Imaging 29: 1685-1696.
-
(2002)
Eur J Nucl Med Mol Imaging
, vol.29
, pp. 1685-1696
-
-
Devous, M.D.S.1
-
70
-
-
0041887079
-
Differential features of metabolic abnormalities between medial and lateral temporal lobe epilepsy: Quantitative analysis of (18)F-FDG PET using SPM
-
Kim YK, Lee DS, Lee SK, Kim SK, Chung CK, et al. (2003) Differential features of metabolic abnormalities between medial and lateral temporal lobe epilepsy: quantitative analysis of (18)F-FDG PET using SPM. J Nucl Med 44: 1006-1012.
-
(2003)
J Nucl Med
, vol.44
, pp. 1006-1012
-
-
Kim, Y.K.1
Lee, D.S.2
Lee, S.K.3
Kim, S.K.4
Chung, C.K.5
-
71
-
-
0141594928
-
Therapeutic strategies for Alzheimer disease: Focus on neuronal reactivation of metabolically impaired neurons
-
Swaab DF, Dubelaar EJ, Scherder EJ, van Someren EJ, Verwer RW (2003) Therapeutic strategies for Alzheimer disease: focus on neuronal reactivation of metabolically impaired neurons. Alzheimer Dis Assoc Disord 17(Suppl 4): S114-22.
-
(2003)
Alzheimer Dis Assoc Disord
, vol.17
, Issue.SUPPL. 4
-
-
Swaab, D.F.1
Dubelaar, E.J.2
Scherder, E.J.3
van Someren, E.J.4
Verwer, R.W.5
-
72
-
-
0034495098
-
Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study
-
Kalmijn S, Mehta KM, Pols HA, Hofman A, Drexhage HA, et al. (2000) Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study. Clin Endocrinol (Oxf) 53: 733-737.
-
(2000)
Clin Endocrinol (Oxf)
, vol.53
, pp. 733-737
-
-
Kalmijn, S.1
Mehta, K.M.2
Pols, H.A.3
Hofman, A.4
Drexhage, H.A.5
-
73
-
-
0043127453
-
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
-
Schubert M, Brazil DP, Burks DJ, Kushner JA, Ye J, et al. (2003) Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation. J Neurosci 23: 7084-7092.
-
(2003)
J Neurosci
, vol.23
, pp. 7084-7092
-
-
Schubert, M.1
Brazil, D.P.2
Burks, D.J.3
Kushner, J.A.4
Ye, J.5
-
74
-
-
12144290448
-
Role for neuronal insulin resistance in neurodegenerative diseases
-
Schubert M, Gautam D, Surjo D, Ueki K, Baudler S, et al. (2004) Role for neuronal insulin resistance in neurodegenerative diseases. Proc Natl Acad Sci USA 101: 3100-3105.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3100-3105
-
-
Schubert, M.1
Gautam, D.2
Surjo, D.3
Ueki, K.4
Baudler, S.5
-
75
-
-
14244253319
-
Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies
-
Iqbal K, Grundke-Iqbal I (2005) Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies. Acta Neuropathol 109: 25-31.
-
(2005)
Acta Neuropathol
, vol.109
, pp. 25-31
-
-
Iqbal, K.1
Grundke-Iqbal, I.2
-
76
-
-
0031928535
-
Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis
-
Hoyer S (1998) Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis. J Neural Transm 105: 415-422.
-
(1998)
J Neural Transm
, vol.105
, pp. 415-422
-
-
Hoyer, S.1
-
77
-
-
0142026832
-
Potential roles of insulin and IGF-1 in Alzheimer's disease
-
Gasparini L, Xu H (2003) Potential roles of insulin and IGF-1 in Alzheimer's disease. Trends Neurosci 26: 404-406.
-
(2003)
Trends Neurosci
, vol.26
, pp. 404-406
-
-
Gasparini, L.1
Xu, H.2
-
78
-
-
33745562235
-
Increased glucose concentration in the hippocampus in early Alzheimer's disease following oral glucose ingestion
-
Haley AP, Knight-Scott J, Simnad VI, Manning CA (2006) Increased glucose concentration in the hippocampus in early Alzheimer's disease following oral glucose ingestion. Magn Reson Imaging 24: 715-720.
-
(2006)
Magn Reson Imaging
, vol.24
, pp. 715-720
-
-
Haley, A.P.1
Knight-Scott, J.2
Simnad, V.I.3
Manning, C.A.4
-
79
-
-
0034440140
-
A unifying hypothesis of Alzheimer's disease. IV. Causation and sequence of events
-
Heininger K (2000) A unifying hypothesis of Alzheimer's disease. IV. Causation and sequence of events. Rev Neurosci 11(Spec No): 213-328.
-
(2000)
Rev Neurosci
, vol.11
, Issue.SPEC NO
, pp. 213-328
-
-
Heininger, K.1
-
80
-
-
0032516493
-
Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution
-
Friedhoff P, Schneider A, Mandelkow EM, Mandelkow E (1998) Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution. Biochemistry 37: 10223-10230.
-
(1998)
Biochemistry
, vol.37
, pp. 10223-10230
-
-
Friedhoff, P.1
Schneider, A.2
Mandelkow, E.M.3
Mandelkow, E.4
-
81
-
-
0023707215
-
Neurofibrillary tangles and senile plaques in aged bears
-
Cork LC, Powers RE, Selkoe DJ, Davies P, Geyer JJ, et al. (1988) Neurofibrillary tangles and senile plaques in aged bears. J Neuropathol Exp Neurol 47: 629-641.
-
(1988)
J Neuropathol Exp Neurol
, vol.47
, pp. 629-641
-
-
Cork, L.C.1
Powers, R.E.2
Selkoe, D.J.3
Davies, P.4
Geyer, J.J.5
-
82
-
-
46449131504
-
Simultaneous Collection of Body Temperature and Activity Data in Burrowing Mammals: A New Technique
-
Long RA, Hut RA, Barnes BM (2007) Simultaneous Collection of Body Temperature and Activity Data in Burrowing Mammals: a New Technique. J Wildl Manage 71: 1375-1379.
-
(2007)
J Wildl Manage
, vol.71
, pp. 1375-1379
-
-
Long, R.A.1
Hut, R.A.2
Barnes, B.M.3
-
83
-
-
0028824741
-
An analysis of factors that induce hibernation in Syrian hamsters
-
Ueda S, Ibuka N (1995) An analysis of factors that induce hibernation in Syrian hamsters. Physiol Behav 58: 653-657.
-
(1995)
Physiol Behav
, vol.58
, pp. 653-657
-
-
Ueda, S.1
Ibuka, N.2
-
84
-
-
66149112547
-
Elevated expression of protein biosynthesis genes in liver and muscle of hibernating black bears (Ursus americanus)
-
Fedorov VB, Goropashnaya AV, Toien O, Stewart NC, Gracey AY, et al. (2009) Elevated expression of protein biosynthesis genes in liver and muscle of hibernating black bears (Ursus americanus). Physiol Genomics 37: 108-118.
-
(2009)
Physiol Genomics
, vol.37
, pp. 108-118
-
-
Fedorov, V.B.1
Goropashnaya, A.V.2
Toien, O.3
Stewart, N.C.4
Gracey, A.Y.5
-
85
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72: 248-254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
|