Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion

Cellular Physiology and Biochemistry

Volumn 34, Issue 3, 2014, Pages 829-841

  Xia, Min ^a   Conley, Sabena M ^a   Li, Guangbi ^a   Li, Pin Lan ^a   Boini, Krishna M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

End stage renal disease; Glomerulosclerosis; hHcys; Inflammasomes; NLRP3

Indexed keywords

ALBUMIN; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; CRYOPYRIN; DESMIN; FOLIC ACID; HOMOCYSTEINE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NEPHRIN; PODOCIN; PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; PRIMER DNA; SMALL INTERFERING RNA;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DELETION; GENETIC TRANSFECTION; GLOMERULOSCLEROSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERHOMOCYSTEINEMIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KIDNEY HYPERTROPHY; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN URINE LEVEL; PROTEINURIA; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URINALYSIS; URINARY EXCRETION; ANIMAL; C57BL MOUSE; COMPLICATION; GENE SILENCING; GENETICS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY;

MUS;

ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; DNA PRIMERS; GENE DELETION; GENE SILENCING; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HYPERHOMOCYSTEINEMIA; INFLAMMASOMES; MALE; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84906609451     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000363046     Document Type: Article

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