-
2
-
-
27144507950
-
Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells
-
McMorrow T, Gaffney MM, Slattery C, et al Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells. Nephrol Dial Transplant. 2005; 20: 2215-25.
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 2215-2225
-
-
McMorrow, T.1
Gaffney, M.M.2
Slattery, C.3
-
3
-
-
0030419494
-
Molecular insights into renal interstitial fibrosis
-
Eddy AA. Molecular insights into renal interstitial fibrosis. J Am Soc Nephrol. 1996; 7: 2495-508.
-
(1996)
J Am Soc Nephrol
, vol.7
, pp. 2495-2508
-
-
Eddy, A.A.1
-
4
-
-
0032512094
-
Pathophysiology of progressive nephropathies
-
Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med. 1998; 339: 1448-56.
-
(1998)
N Engl J Med
, vol.339
, pp. 1448-1456
-
-
Remuzzi, G.1
Bertani, T.2
-
5
-
-
0034785407
-
Transforming growth factor-beta, basement membrane, and epithelial-mesenchymal transdifferentiation: implications for fibrosis in kidney disease
-
Stahl PJ, Felsen D. Transforming growth factor-beta, basement membrane, and epithelial-mesenchymal transdifferentiation: implications for fibrosis in kidney disease. Am J Pathol. 2001; 159: 1187-92.
-
(2001)
Am J Pathol
, vol.159
, pp. 1187-1192
-
-
Stahl, P.J.1
Felsen, D.2
-
6
-
-
0346727324
-
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
-
Sato M, Muragaki Y, Saika S, et al Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest. 2003; 112: 1486-94.
-
(2003)
J Clin Invest
, vol.112
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
-
7
-
-
1642336325
-
Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway
-
Li JH, Wang W, Huang XR, et al Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway. Am J Pathol. 2004; 164: 1389-97.
-
(2004)
Am J Pathol
, vol.164
, pp. 1389-1397
-
-
Li, J.H.1
Wang, W.2
Huang, X.R.3
-
8
-
-
10744229444
-
Transdifferentiation of cultured tubular cells induced by hypoxia
-
Manotham K, Tanaka T, Matsumoto M, et al Transdifferentiation of cultured tubular cells induced by hypoxia. Kidney Int. 2004; 65: 871-80.
-
(2004)
Kidney Int
, vol.65
, pp. 871-880
-
-
Manotham, K.1
Tanaka, T.2
Matsumoto, M.3
-
9
-
-
20544437490
-
Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells
-
Rhyu DY, Yang Y, Ha H, et al Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol. 2005; 16: 667-75.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 667-675
-
-
Rhyu, D.Y.1
Yang, Y.2
Ha, H.3
-
10
-
-
34548602977
-
Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin
-
Zhang A, Jia Z, Guo X, et al Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin. Am J Physiol Renal Physiol. 2007; 293: F723-31.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Zhang, A.1
Jia, Z.2
Guo, X.3
-
11
-
-
0036020210
-
Interleukin-1beta induces human proximal tubule cell injury, alpha-smooth muscle actin expression and fibronectin production
-
Vesey DA, Cheung CW, Cuttle L, et al Interleukin-1beta induces human proximal tubule cell injury, alpha-smooth muscle actin expression and fibronectin production. Kidney Int. 2002; 62: 31-40.
-
(2002)
Kidney Int
, vol.62
, pp. 31-40
-
-
Vesey, D.A.1
Cheung, C.W.2
Cuttle, L.3
-
12
-
-
0034799176
-
Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation
-
Zeisberg M, Bonner G, Maeshima Y, et al Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation. Am J Pathol. 2001; 159: 1313-21.
-
(2001)
Am J Pathol
, vol.159
, pp. 1313-1321
-
-
Zeisberg, M.1
Bonner, G.2
Maeshima, Y.3
-
13
-
-
33748309231
-
Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38
-
Aksoy P, Escande C, White TA, et al Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38. Biochem Biophys Res Commun. 2006; 349: 353-9.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 353-359
-
-
Aksoy, P.1
Escande, C.2
White, T.A.3
-
14
-
-
33744509311
-
Regulation of intracellular levels of NAD: a novel role for CD38
-
Aksoy P, White TA, Thompson M, et al Regulation of intracellular levels of NAD: a novel role for CD38. Biochem Biophys Res Commun. 2006; 345: 1386-92.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 1386-1392
-
-
Aksoy, P.1
White, T.A.2
Thompson, M.3
-
15
-
-
2442669051
-
Regulation and identity of intracellular calcium stores involved in membrane cross talk in the early distal tubule of the frog kidney
-
Fowler MR, Cooper GJ, Hunter M. Regulation and identity of intracellular calcium stores involved in membrane cross talk in the early distal tubule of the frog kidney. Am J Physiol Renal Physiol. 2004; 286: F1219-25.
-
(2004)
Am J Physiol Renal Physiol
, vol.286
-
-
Fowler, M.R.1
Cooper, G.J.2
Hunter, M.3
-
16
-
-
35348884892
-
ADP-ribosyl cyclase and ryanodine receptor activity contribute to basal renal vasomotor tone and agonist-induced renal vasoconstriction in vivo
-
Thai TL, Fellner SK, Arendshorst WJ. ADP-ribosyl cyclase and ryanodine receptor activity contribute to basal renal vasomotor tone and agonist-induced renal vasoconstriction in vivo. Am J Physiol Renal Physiol. 2007; 293: F1107-14.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Thai, T.L.1
Fellner, S.K.2
Arendshorst, W.J.3
-
17
-
-
0034816834
-
cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells
-
Yusufi AN, Cheng J, Thompson MA, et al cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells. Am J Physiol Renal Physiol. 2001; 281: F91-F102.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Yusufi, A.N.1
Cheng, J.2
Thompson, M.A.3
-
18
-
-
0033593198
-
CD38 disruption impairs glucose-induced increases in cyclic ADP-ribose, [Ca2+]i, and insulin secretion
-
Kato I, Yamamoto Y, Fujimura M, et al CD38 disruption impairs glucose-induced increases in cyclic ADP-ribose, [Ca2+]i, and insulin secretion. J Biol Chem. 1999; 274: 1869-72.
-
(1999)
J Biol Chem
, vol.274
, pp. 1869-1872
-
-
Kato, I.1
Yamamoto, Y.2
Fujimura, M.3
-
19
-
-
0037336165
-
Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption
-
Sun L, Iqbal J, Dolgilevich S, et al Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption. FASEB J. 2003; 17: 369-75.
-
(2003)
FASEB J
, vol.17
, pp. 369-375
-
-
Sun, L.1
Iqbal, J.2
Dolgilevich, S.3
-
20
-
-
0035173647
-
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo
-
Partida-Sanchez S, Cockayne DA, Monard S, et al Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo. Nat Med. 2001; 7: 1209-16.
-
(2001)
Nat Med
, vol.7
, pp. 1209-1216
-
-
Partida-Sanchez, S.1
Cockayne, D.A.2
Monard, S.3
-
21
-
-
12144285678
-
Regulation of dendritic cell trafficking by the ADP-ribosyl cyclase CD38: impact on the development of humoral immunity
-
Partida-Sanchez S, Goodrich S, Kusser K, et al Regulation of dendritic cell trafficking by the ADP-ribosyl cyclase CD38: impact on the development of humoral immunity. Immunity. 2004; 20: 279-91.
-
(2004)
Immunity
, vol.20
, pp. 279-291
-
-
Partida-Sanchez, S.1
Goodrich, S.2
Kusser, K.3
-
22
-
-
43549118443
-
CD38 induces differentiation of immature transitional 2 B lymphocytes in the spleen
-
Rodriguez-Alba JC, Moreno-Garcia ME, Sandoval-Montes C, et al CD38 induces differentiation of immature transitional 2 B lymphocytes in the spleen. Blood. 2008; 111: 3644-52.
-
(2008)
Blood
, vol.111
, pp. 3644-3652
-
-
Rodriguez-Alba, J.C.1
Moreno-Garcia, M.E.2
Sandoval-Montes, C.3
-
23
-
-
2542494061
-
Signaling at the slit diaphragm
-
Benzing T. Signaling at the slit diaphragm. J Am Soc Nephrol. 2004; 15: 1382-91.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1382-1391
-
-
Benzing, T.1
-
24
-
-
39549098861
-
Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria
-
Li Y, Kang YS, Dai C, et al Epithelial-to-mesenchymal transition is a potential pathway leading to podocyte dysfunction and proteinuria. Am J Pathol. 2008; 172: 299-308.
-
(2008)
Am J Pathol
, vol.172
, pp. 299-308
-
-
Li, Y.1
Kang, Y.S.2
Dai, C.3
-
25
-
-
33745058119
-
The podocyte's response to injury: role in proteinuria and glomerulosclerosis
-
Shankland SJ. The podocyte's response to injury: role in proteinuria and glomerulosclerosis. Kidney Int. 2006; 69: 2131-47.
-
(2006)
Kidney Int
, vol.69
, pp. 2131-2147
-
-
Shankland, S.J.1
-
26
-
-
34250006557
-
The spectrum of podocytopathies: a unifying view of glomerular diseases
-
Wiggins RC. The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney Int. 2007; 71: 1205-14.
-
(2007)
Kidney Int
, vol.71
, pp. 1205-1214
-
-
Wiggins, R.C.1
-
27
-
-
30344450362
-
Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury
-
Macconi D, Bonomelli M, Benigni A, et al Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury. Am J Pathol. 2006; 168: 42-54.
-
(2006)
Am J Pathol
, vol.168
, pp. 42-54
-
-
Macconi, D.1
Bonomelli, M.2
Benigni, A.3
-
28
-
-
0034836835
-
Apoptosis in podocytes induced by TGF-beta and Smad7
-
Schiffer M, Bitzer M, Roberts IS, et al Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest. 2001; 108: 807-16.
-
(2001)
J Clin Invest
, vol.108
, pp. 807-816
-
-
Schiffer, M.1
Bitzer, M.2
Roberts, I.S.3
-
29
-
-
29144490392
-
Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene
-
Wharram BL, Goyal M, Wiggins JE, et al Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol. 2005; 16: 2941-52.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2941-2952
-
-
Wharram, B.L.1
Goyal, M.2
Wiggins, J.E.3
-
30
-
-
33845238078
-
Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors
-
Nagase M, Yoshida S, Shibata S, et al Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors. J Am Soc Nephrol. 2006; 17: 3438-46.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 3438-3446
-
-
Nagase, M.1
Yoshida, S.2
Shibata, S.3
-
31
-
-
33645577952
-
Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury
-
Zou J, Yaoita E, Watanabe Y, et al Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Virchows Arch. 2006; 448: 485-92.
-
(2006)
Virchows Arch
, vol.448
, pp. 485-492
-
-
Zou, J.1
Yaoita, E.2
Watanabe, Y.3
-
32
-
-
58149395046
-
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats
-
Yi F, Xia M, Li N, et al Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats. Hypertension. 2009; 53: 90-6.
-
(2009)
Hypertension
, vol.53
, pp. 90-96
-
-
Yi, F.1
Xia, M.2
Li, N.3
-
33
-
-
0021179653
-
Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats
-
Raij L, Azar S, Keane W. Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats. Kidney Int. 1984; 26: 137-43.
-
(1984)
Kidney Int
, vol.26
, pp. 137-143
-
-
Raij, L.1
Azar, S.2
Keane, W.3
-
34
-
-
77956234760
-
Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet
-
Boini KM, Zhang C, Xia M, et al Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet. J Pharmacol Exp Ther. 2010; 334: 839-46.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 839-846
-
-
Boini, K.M.1
Zhang, C.2
Xia, M.3
-
35
-
-
33745711919
-
Inhibition of ceramide-redox signaling pathway blocks glomerular injury in hyperhomocysteinemic rats
-
Yi F, Zhang AY, Li N, et al Inhibition of ceramide-redox signaling pathway blocks glomerular injury in hyperhomocysteinemic rats. Kidney Int. 2006; 70: 88-96.
-
(2006)
Kidney Int
, vol.70
, pp. 88-96
-
-
Yi, F.1
Zhang, A.Y.2
Li, N.3
-
36
-
-
43449128852
-
Salt-sensitive hypertension induced by decoy of transcription factor hypoxia-inducible factor-1alpha in the renal medulla
-
Li N, Chen L, Yi F, et al Salt-sensitive hypertension induced by decoy of transcription factor hypoxia-inducible factor-1alpha in the renal medulla. Circ Res. 2008; 102: 1101-8.
-
(2008)
Circ Res
, vol.102
, pp. 1101-1108
-
-
Li, N.1
Chen, L.2
Yi, F.3
-
37
-
-
34548695678
-
Quantitative colocalization analysis of multicolor confocal immunofluorescence microscopy images: pushing pixels to explore biological phenomena
-
Zinchuk V, Zinchuk O, Okada T. Quantitative colocalization analysis of multicolor confocal immunofluorescence microscopy images: pushing pixels to explore biological phenomena. Acta Histochem Cytochem. 2007; 40: 101-11.
-
(2007)
Acta Histochem Cytochem
, vol.40
, pp. 101-111
-
-
Zinchuk, V.1
Zinchuk, O.2
Okada, T.3
-
38
-
-
78751475177
-
Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin
-
Xia M, Zhang C, Boini KM, et al Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin. Cardiovasc Res. 2011; 89: 401-19.
-
(2011)
Cardiovasc Res
, vol.89
, pp. 401-419
-
-
Xia, M.1
Zhang, C.2
Boini, K.M.3
-
40
-
-
67650996280
-
Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease
-
Acloque H, Adams MS, Fishwick K, et al Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest. 2009; 119: 1438-49.
-
(2009)
J Clin Invest
, vol.119
, pp. 1438-1449
-
-
Acloque, H.1
Adams, M.S.2
Fishwick, K.3
-
41
-
-
60749137389
-
EMT and proteinuria as progression factors
-
Strutz FM. EMT and proteinuria as progression factors. Kidney Int. 2009; 75: 475-81.
-
(2009)
Kidney Int
, vol.75
, pp. 475-481
-
-
Strutz, F.M.1
-
42
-
-
33750712380
-
Renal fibroblasts and myofibroblasts in chronic kidney disease
-
Strutz F, Zeisberg M. Renal fibroblasts and myofibroblasts in chronic kidney disease. J Am Soc Nephrol. 2006; 17: 2992-8.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2992-2998
-
-
Strutz, F.1
Zeisberg, M.2
-
43
-
-
44249112353
-
CD2-associated protein is widely expressed and differentially regulated during embryonic development
-
Lehtonen S, Tienari J, Londesborough A, et al CD2-associated protein is widely expressed and differentially regulated during embryonic development. Differentiation. 2008; 76: 506-17.
-
(2008)
Differentiation
, vol.76
, pp. 506-517
-
-
Lehtonen, S.1
Tienari, J.2
Londesborough, A.3
-
44
-
-
0029091682
-
Identification and characterization of a fibroblast marker: FSP1
-
Strutz F, Okada H, Lo CW, et al Identification and characterization of a fibroblast marker: FSP1. J Cell Biol. 1995; 130: 393-405.
-
(1995)
J Cell Biol
, vol.130
, pp. 393-405
-
-
Strutz, F.1
Okada, H.2
Lo, C.W.3
-
45
-
-
70349263307
-
Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy
-
Yamaguchi Y, Iwano M, Suzuki D, et al Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy. Am J Kidney Dis. 2009; 54: 653-64.
-
(2009)
Am J Kidney Dis
, vol.54
, pp. 653-664
-
-
Yamaguchi, Y.1
Iwano, M.2
Suzuki, D.3
-
46
-
-
0036854980
-
Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy
-
Yang J, Shultz RW, Mars WM, et al Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy. J Clin Invest. 2002; 110: 1525-38.
-
(2002)
J Clin Invest
, vol.110
, pp. 1525-1538
-
-
Yang, J.1
Shultz, R.W.2
Mars, W.M.3
-
47
-
-
67650653239
-
Mice lacking the ADP ribosyl cyclase CD38 exhibit attenuated renal vasoconstriction to angiotensin II, endothelin-1, and norepinephrine
-
Thai TL, Arendshorst WJ. Mice lacking the ADP ribosyl cyclase CD38 exhibit attenuated renal vasoconstriction to angiotensin II, endothelin-1, and norepinephrine. Am J Physiol Renal Physiol. 2009; 297: F169-76.
-
(2009)
Am J Physiol Renal Physiol.
, vol.297
-
-
Thai, T.L.1
Arendshorst, W.J.2
-
48
-
-
34250799639
-
Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats
-
Yi F, dos Santos EA, Xia M, et al Podocyte injury and glomerulosclerosis in hyperhomocysteinemic rats. Am J Nephrol. 2007; 27: 262-8.
-
(2007)
Am J Nephrol
, vol.27
, pp. 262-268
-
-
Yi, F.1
dos Santos, E.A.2
Xia, M.3
-
49
-
-
14644431025
-
Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney
-
Hou CC, Wang W, Huang XR, et al Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney. Am J Pathol. 2005; 166: 761-71.
-
(2005)
Am J Pathol
, vol.166
, pp. 761-771
-
-
Hou, C.C.1
Wang, W.2
Huang, X.R.3
-
50
-
-
12744278106
-
An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney
-
Koike H, Tomita N, Azuma H, et al An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney. J Gene Med. 2005; 7: 108-16.
-
(2005)
J Gene Med
, vol.7
, pp. 108-116
-
-
Koike, H.1
Tomita, N.2
Azuma, H.3
-
51
-
-
0037498439
-
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
-
Lan HY, Mu W, Tomita N, et al Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol. 2003; 14: 1535-48.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1535-1548
-
-
Lan, H.Y.1
Mu, W.2
Tomita, N.3
-
52
-
-
38949193863
-
Ultrasound-based nonviral gene delivery induces bone formation in vivo
-
Sheyn D, Kimelman-Bleich N, Pelled G, et al Ultrasound-based nonviral gene delivery induces bone formation in vivo. Gene Ther. 2008; 15: 257-66.
-
(2008)
Gene Ther
, vol.15
, pp. 257-266
-
-
Sheyn, D.1
Kimelman-Bleich, N.2
Pelled, G.3
|